• 한국자원리싸이클링학회:학술대회논문집
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• 한국자원리싸이클링학회 1993년도 EARTH 발표논문초록
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• pp.25.2-25
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• 1993

• 노동경제논집
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• 제29권2호
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• pp.117-143
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• 2006

본 논문은 1963년부터 2003년까지의 40년간의 국내의 금속, 화학, 금융, 자동차 운수부문(sector)의 조합원 수가 시기별로 어떤 증가나 감소 패턴을 보이는가를 규명한다. 또한 이 4개 부문에 속한 산업(industry)인 금속부문의 자동차 조립, 자동차 부품, 조선산업, 화학부문의 시멘트, 석유정제, 제약산업, 금융부문의 민간은행업, 그리고 자동차 운수부문의 시내버스업에서 노조 조직률을 추정하여 산업별로 상대적 노조규모의 차이를 보여준다. 이러한 노조규모의 절대적인 혹은 상대적인 규모의 시기별 변화나 산업별 차이가 각 부문이나 산업이 처한 경제적 환경(성장 단계나 경로)과 제도적 환경(정부개입의 유형이나 정도) 및 사회적 환경(근로자들의 학력, 성별, 연령 혹은 회사의 규모 등의 산업구조)에 영향을 받는 사용자들이나 노조의 태도나 선택에 의해 설명된다. 부문이나 산업수준의 다양성을 고려한 본 논문의 미시적인 사회 경제적 이론들은 선진국의 국제비교 노사관계의 최근 연구들에서 나타나는 미시적인 연구의 필요성의 증가와 맥을 같이한다.

• Bulletin of the Korean Chemical Society
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• 제34권5호
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• pp.1541-1542
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• 2013

• 한국균학회소식:학술대회논문집
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• 한국균학회 2009년도 춘계학술대회 및 임시총회
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• pp.41-47
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• 2009

• Bulletin of the Korean Chemical Society
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• 제34권8호
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• pp.2297-2304
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• 2013

A series of novel benzimidazole derivatives bearing a heterocyclic ring as oxadiazole (21-32), thiadiazole (33-34), triazole (35-36) were synthesized and evaluated for their activities against Coxsackie virus B3 and B6 in Vero cells. Compounds 21-26, 31-36 with moieties of 2'-pyridyl, 3'-pyridyl and 4'-pyridyl at the 2-position and oxadiazoles, thiadiazole, or triazole substituent at the 4- or 5-position generally displayed activities against CVB3 and CVB6. Especially compound 24 ($IC_{50}=1.08{\mu}g/mL$, SI = 61.7 against CVB3) was the promising candidate as lead compound for anti-enteroviral drug. It was observed in the incorporation of heterocyclic rings in benzimidazole at the 5-position could enhance their biological activities.

• Journal of Microbiology and Biotechnology
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• 제21권6호
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• pp.599-603
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• 2011

A new geldanamycin (GDM) derivative was discovered and isolated from the fermentation broth of Streptomyces hygroscopicus 17997. Its chemical structure was elucidated as thiazinogeldanamycin by LC-MS, sulfur analysis, and NMR. The addition of cysteine to the fermentation medium significantly stimulated the production level of thiazinogeldanamycin, suggesting cysteine as a precursor of thiazinogeldanamycin production. Although showing a decreased cytotoxicity against HepG2 cancer cells, thiazinogeldanamycin exhibited an improved water solubility and photostability. Thiazinogeldanamycin may represent the first natural GDM derivative characterized so far that uses GDM as its precursor. Its appearance also clearly indicates that an appropriate end-point of fermentation is of critical importance for the maximal production of GDM by Streptomyces hygroscopicus 17997.

• 한국염색가공학회지
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• 제16권1호
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• pp.26-33
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• 2004

Two reactive disperse dyes having $\alpha$-bromoacrylamide or acrylamide group were synthesized and their dyeing properties were compared with a disperse dye. Dyeing properties of reactive disperse dyes were strongly influenced by the chemical structure of reactive group. The amount of absorbed reactive disperse dye containing $\alpha$-bromoacrylamide group on polyester fiber was less than the disperse dye, and that on nylon fiber was much higher. When polyester and nylon fiber were simultaneously dyed in a dye pot, nylon fiber absorbed the reactive disperse dye more than polyester fiber. The reactive disperse dye having acrylamide group could reduces difference in color depth to a large extent, but the application of carrier or variation of dyebath pH were not sufficient for giving the same color depth to both fibers. The N/P union fabric could be dyed with the reactive disperse dye and its wash fastness were good to excellent.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제38권4호
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• pp.195-203
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• 2012

Dental implants using titanium have greatly advanced through the improvement of designs and surface treatments. Nonetheless, the anatomical limits and physiological changes of the patient are still regarded as obstacles in increasing the success rate of implants further, even with the enhancement of implant products. So there have been many efforts to overcome these limits. The intrinsic potential for bone regeneration can be stimulated through adjuvant treatments with the continuous improvement of implant properties, and this can play an important role in achieving optimum osseointegration toward peripheral bone tissue and securing ultimate long-term implant stability in standard surgical procedures. For this purpose, various chemical, biological, or biophysical measures were developed such as bone grafts, materials, pharmacological agents, growth factors, and bone formation proteins. The biophysical stimulation of bone union includes non-invasive and safe methods. In the beginning, it was developed as a method to enhance the healing of fractures, but later evolved into Pulsed Electromagnetic Field, Low-Intensity Pulsed Ultrasound, and Low-Level Laser Therapy. Their beneficial effects were confirmed in many studies. This study sought to examine bone-implant union and its latest trend as well as the biophysical stimulation method to enhance the union. In particular, this study suggested the enhancement of the function of cells and tissues under a disadvantageous bone metabolism environment through such adjunctive stimulation. This study is expected to serve as a treatment guideline for implant-bone union under unfavorable circumstances caused by systemic diseases hampering bone metabolism or the host environment.

• BMB Reports
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• 제40권2호
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• pp.196-204
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• 2007

Our previous study has shown that sodium selenite can cause apoptosis in acute promyelocytic leukemia-derived NB4 cells in a caspase-dependent manner, but the detailed mechanism is unknown. Here we demonstrate a requirement for extracellular signal-regulated protein kinase (ERK) in mediating sodium selenite -induced apoptosis in NB4 cell. Though no apparent elevation of ERK activity was observed during the apoptosis in NB4 cells caused by 20 μM sodium selenite treatment, PD98059 and U0126, specific chemical inhibitors of the MEK/ERK signaling pathway, were shown to strongly prevent the apoptosis process, while ERK activator TPA enhanced the process. It is also known that p38 MAPK inhibitor SB203580 and JNK inhibitor SP600125 had slight effects on apoptosis. Further study indicated that ERK exerted its proapoptotic effect only at the early stage of apoptosis and played an antiapoptotic role at the later stages. Taken together, our findings suggest that ERK plays an active role in mediating sodium seleniteinduced apoptosis in NB4 cells .

• The Korean Journal of Pain
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• 제34권3호
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• pp.271-287
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• 2021

Background: Postoperative pain management is crucial for patients undergoing total knee arthroplasty (TKA). There have been many recent clinical trials on post-TKA peripheral nerve block; however, they have reported inconsistent findings. In this meta-analysis, we aimed to comprehensively analyze studies on post-TKA analgesia to provide evidence-based clinical suggestions. Methods: We performed a computer-based query of PubMed, Embase, the Cochrane Library, and the Web of Science to retrieve related articles using neurothe following search terms: nerve block, nerve blockade, chemodenervation, chemical neurolysis, peridural block, epidural anesthesia, extradural anesthesia, total knee arthroplasty, total knee replacement, partial knee replacement, and others. After quality evaluation and data extraction, we analyzed the complications, visual analogue scale (VAS) score, patient satisfaction, perioperative opioid dosage, and rehabilitation indices. Evidence was rated using the Grading of Recommendations Assessment, Development, and Evaluation approach. Results: We included 16 randomized controlled trials involving 981 patients (511 receiving peripheral nerve block and 470 receiving epidural block) in the final analysis. Compared with an epidural block, a peripheral nerve block significantly reduced complications. There were no significant between-group differences in the postoperative VAS score, patient satisfaction, perioperative opioid dosage, and rehabilitation indices. Conclusions: Our findings demonstrate that the peripheral nerve block is superior to the epidural block in reducing complications without compromising the analgesic effect and patient satisfaction. Therefore, a peripheral nerve block is a safe and effective postoperative analgesic method with encouraging clinical prospects.