• Journal of the Korean GEO-environmental Society
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• v.13 no.4
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• pp.45-51
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• 2012

The shear strength of weathered granite soils under unsaturated condition was evaluated by $K_0$ consolidated triaxial tests. Various matric suctions in the unsaturated triaxial tests were applied using suction-controlled triaxial test apparatus for weathered granite soils obtained in Daegu. Soil water characteristic curve (SWCC) laboratory tests for drying and wetting procedure were performed and van Genuchten curves were fitted by experimental results. The contribution of matric suction in unsaturated soils is directly correlated to effective stress and evaluated from SWCCs. The effective stresses were estimated from these SWCCs and the relationship between effective stress and unsaturated shear strength was determined. In the effective stress description, the unsaturated shear strength with respect to various suctions indicates unique relationship and almost the same as that of the saturated envelope.

• Journal of the Korean GEO-environmental Society
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• v.9 no.3
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• pp.51-60
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• 2008

Soil nailing systems are generally many used to the temporary structure in underground excavations and reinforcements of slopes in Korea. However, large-scaled experimental studies related to soil nailing systems are mostly studies related to performance monitoring and field pullout tests. Specially, there are no researches related in the large scaled load tests of soil nailed walls in Korea. In this study, a case study on the large scaled load tests of soil nailed walls is introduced and the behavior characteristic of them is investigated. Also, they are proposed allowable deformation corresponding to the serviceability limit of soil nailed walls and ultimate deformation corresponding to the collapse state of the walls. These results can be applied to the maintenance management of soil nailed walls. And analysis on the required minimum factor of safety of soil nailed walls using the relation curve of load ratio and deformation ratio are carried out.

• Journal of Korean Association for Spatial Structures
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• v.12 no.1
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• pp.77-85
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• 2012

The membrane structure maintains stable form by giving initial tension to ductile membrane and increasing the stiffness of exterior that is much adopted in the large span spatial structure by making its thickness thin. This kind of membrane structure has characteristic that can express free-form curve, so the selection of structural form is very important. So, this paper proposes the expression of free-form surface based on NURBS basis function and the finite element method considering geometrical nonlinearity for the deduction of large deformation result. Also, for minimizing the approximation of the surface that is derived from the form-finding result, the interface method that change finite element mesh to NURBS is proposed. So, the optimum surface of free-form membrane is derived.

• Journal of the Korean Geotechnical Society
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• v.21 no.8
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• pp.45-53
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• 2005

Shallow slope failures in residual soil during periods of prolonged infiltration are common over the world. Therefore, this study examines an approximate method to estimate the influence of infiltration on surficial stability of slopes by one-dimensional infiltration model. Modified GAML model based on the Green-Ampt model was extended to predict the infiltration behavior of two-layered slope. Then, the model has been considered to evaluate the likelihood of shallow slope failure which is induced by a particular rainfall event that accounts for the rainfall intensity and duration for various return periods in two-layered soil profile. The results obtained from the approximate method were compared with those obtained from numerical analyses. According to the results, with the use of properly estimated input parameters, the proposed method was found to give good results that agree reasonably well to those of the more rigorous finite element analyses.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.933-943
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• 2009

Axial loads and shaft resistances can be calculated by load transfer analysis using strain data with load level. In load transfer analysis, the elastic modulus of concrete is a one of the most important parameters to consider. The elastic modulus, $E_{50}$, suggested by ACI (American Concrete Institute), has been commonly used. However, elastic modulus of concrete shows nonlinear stress-strain characteristic, so nonlinearity should be considered in load transfer analysis. In this paper, a load transfer analysis was performed by using data obtained from bi-directional pile load tests for four cases of drilled shafts. For consideration of nonlinearity, elastic modulus was calculated by both the Fellenius method and the nonlinear method, assuming the stress-strain relation of concrete to be a quadratic function, and then, the calculated elastic modulus was applied to the estimation of shaft resistance. The calculated shaft resistances were compared with the result obtained using the constant elastic modulus of ACI code. It was found that the f-w curves are similar to each method, and elastic modulus and shaft resistances decreased as strain increased. Moreover, shaft resistances estimated from elastic modulus considering nonlinearity were 5~15% different than those obtained using the constant elastic modulus.

• Genomics & Informatics
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• v.13 no.3
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• pp.70-75
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• 2015

MicroRNAs (miRNAs) have been demonstrated to play an important role in carcinogenesis. Previous studies revealed that miRNAs are present in human plasma in a remarkably stable form that is protected from endogenous RNase activity. In this study, we measured the plasma expression levels of three miRNAs (miR-21, miR-27a, and miR-155) to investigate the usefulness of miRNAs for gastric cancer detection. We initially examined plasma miRNA expression levels in a screening cohort consisting of 15 patients with gastric cancer and 15 healthy controls from Korean population, using TaqMan quantitative real-time polymerase chain reaction. We observed that the expression level of miR-27a was significantly higher in patients with gastric cancer than in healthy controls, whereas the miR-21 and miR-155a expression levels were not significantly higher in the patients with gastric cancer. Therefore, we further validated the miR-27a expression level in 73 paired gastric cancer tissues and in a validation plasma cohort from 35 patients with gastric cancer and 35 healthy controls. In both the gastric cancer tissues and the validation plasma cohort, the miR-27a expression levels were significantly higher in patients with gastric cancer. Receiver-operator characteristic (ROC) analysis of the validation cohort, revealed an area under the ROC curve value of 0.70 with 75% sensitivity and 56% specificity in discriminating gastric cancer. Thus, the miR-27a expression level in plasma could be a useful biomarker for the diagnosis and/or prognosis of gastric cancer.

• Journal of Haehwa Medicine
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• v.19 no.1
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• pp.87-98
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• 2010

There are four kinds of diagnosis methods in oriental medicine, and viewing diagnosis(望診) is the most important method among them. There are two ways in viewing diagnosis. These are viewing shape(觀形) and inspecting color(察色). Viewing shape diagnosis includes observation on geometric curve that is made by prominence of bones or lump of flesh, and examination on symmetric disparity and balance of vertical length among three vertical section of face. Inspecting color is literally inspecting several specified region of face. By Viewing shape, we can learn about characteristic physical mechanism of individuals, and basic disposition of reaction from inside and outside infinite stimulations. On the other hand, by inspecting color, we can estimate the very present pathologic and physiologic status of the patient. the estimation is based on principle that inside body changes reveal some reflections on facial skin surface. When you diagnosis patients with inspecting color method, It is important to distinguish color delicately, and to know where to see and what to know from it. The most important and frequently mentioned regions are myong-dang(明堂), eyes(眼) and In-dang(印堂). Myong-dang(明堂) indicates nose. In-dang(印堂) indicates the space between eyebrows. Unlike myong-dang(印堂) and eyes, In-dang(印堂) is occasionally treated as a trivial region then others. But, from research on classical books of facial examination and consideration of it's locational meanings, we've learned In-dang(印堂) is very important in viewing diagnosis, because this region is crossing of the other two regions and this fact means this region expresses the spiritual status as well as physical status in one region.

• Korean Journal of Biological Psychiatry
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• v.16 no.2
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• pp.112-120
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• 2009

Objectives : Depression is a common psychiatric disorder in cancer patients. The Brief Edinburgh Depression Scale(BEDS), which is an abbreviated version of the Edinburgh Depression Scale, may serve as a useful tool in screening for the depression in patients with the medical illnesses. This report investigated the reliability and validity of the Korean Version of the BEDS(K-BEDS) for the depression in cancer patients. Methods : One-hundred cancer patients were enrolled in this study. All subjects completed the K-BEDS, the Hospital Anxiety Depression Scale(HADS), and the Karnofsky Performance Status Scale(KPSS). Reliability, validity and Receiver Operating Characteristic(ROC) curve analysis measures were assessed. Results : The K-BEDS showed good internal consistency(Cronbach ${\alpha}$=0.77) and test-retest reliability(0.94, p<0.001). All item-total correlations were above 0.3. Also, it revealed moderate correlation with the depression subscale of the HADS(r=0.617), but no correlation with the KPSS. Exploratory factor analysis produced only one factor, accounting for 47.1% of the total variance. The most valid cutoff value to screen for depression was a total score of 5 on the K-BEDS, which showed sensitivity of 62.5% and specificity of 86.4% with a positive predictive value of 4.60 and a negative predictive value of 0.43.

• Investigative Magnetic Resonance Imaging
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• v.20 no.4
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• pp.231-240
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• 2016

Purpose: To determine whether liver stiffness (LS) measured by magnetic resonance elastography (MRE) can predict the outcome of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Materials and Methods: A total of 107 patients with Child-Pugh class A liver function who were treated with RFA for single HCC and who had undergone a gradient-echo MRE within 6 months before RFA were included. We evaluated the relationship between the LS values and the ablation volume, local tumor progression (LTP), and intrahepatic distant recurrence (IDR). We also constructed receiver operating characteristic (ROC) curves to examine the role of LS in predicting liver function deterioration, which was defined as an increase of Child-Pugh score by one point or more at 1 year after RFA. Results: There was no significant correlation between LS and ablation volume, and neither time to LTP nor IDR was associated with LS. Among the 66 patients who did not have recurrence 1 year after RFA, 5 patients (7.6%) developed liver function deterioration. A high LS value was significantly associated with development of liver function deterioration after RFA and the area under the ROC curve was 0.764 (95% CI 0.598-0.929, P = 0.003). Conclusion: LS measured by MRE could not predict ablation volume and tumor recurrence. However, high LS values were significantly associated with development of liver function deterioration.

• Journal of the Korea Society for Simulation
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• v.22 no.1
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• pp.1-8
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• 2013

A higher penetration of renewable energy sources and adoption of renewable portfolio standard(RPS), the penetration of distributed generators(DGs) into power distribution network is becoming a threat for the safe operation of distribution network. The ground fault current of DGs can cause parasitic trip and mal-trip of protective device in the power distribution network. KEPRI has developed a simulation program for current setting of protective devices in DGs connected distribution network. In this study, we analyzed fault currents of a sample network in two cases, i.e. case 1 is for no DG connection, case 2 for a DG connection. We performed protection coordination for relays installed in the network and analyzed the contribution of a DG.