• Clinical and Experimental Pediatrics
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• v.59 no.sup1
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• pp.116-120
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• 2016

Congenital hyperinsulinism (CHI) is a rare condition that can cause irreversible brain damage during the neonatal period owing to the associated hypoglycemia. Hypoglycemia in CHI occurs secondary to the dysregulation of insulin secretion. CHI has been established as a genetic disorder of islet-cell hyperplasia, associated with a mutation of the ABCC8 or KCNJ11 genes, which encode the sulfonylurea receptor 1 and the inward rectifying potassium channel (Kir6.2) subunit of the ATP-sensitive potassium channel, respectively. We report the case of a female newborn infant who presented with repetitive seizures and episodes of apnea after birth, because of hypoglycemia. Investigations revealed hypoglycemia with hyperinsulinemia, but no ketone bodies, and a low level of free fatty acids. High dose glucose infusion, enteral feeding, and medications could not maintain the patient's serum glucose level. Genetic testing revealed a new variation of ABCC8 mutation. Therefore, we report this case of CHI caused by a novel mutation of ABCC8 in a half-Korean newborn infant with diazoxide-unresponsive hyperinsulinemic hypoglycemia.

• Proceedings of the Materials Research Society of Korea Conference
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• 2010.05a
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• pp.31.1-31.1
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• 2010

Various ZnO nanostructures were synthesized and ZnO nanostructure-based self-assembled transistors were fabricated. Compared to spindle and flower like nanostructure, the ZnO nanorod (NR) structure showed much stronger gate controllability, and greatly enhanced device performance, demonstrating that this structural variation leads to significant differences of the nanostructure network-based device performance. Also, patterned dry transfer-printing technique that can generate monolayer-like percolating networks of ZnO NRs has been developed. The method exploits the contact area difference between NR-NR and NR-substrate, rather than elaborate tailoring of surface chemistry or energetic. The devices prepared by the transferring method exhibited on/off current ratio, and mobility of ${\sim}2.7{\times}10^4$ and ${\sim}1.03\;cm^2/V{\cdot}s$, respectively. Also, they exhibited showing lower off-current and stronger gate controllability due to defined-channel between electrodes and monolayer-like network channel configuration. With multilayer stacks of nanostructures on stamp, the monolayer-like printing can be repeated many times, possibly on large area substrate, due to self-regulating printing characteristics. The method may enable high-performance macroelectronics with materials that have high aspect ratio.

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.386-390
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• 2004

하천은 자연 상태에서 내부분 단일 하천이 아닌 몇 개의 지류가 본류와 만나는 복잡한 하천망을 구성하며 하류로 흘러간다. 이 때 본류와 지류가 만나는 합류부에서는 본류와 지류의 합류각도나 유량에 의해 수리학적인 특성이 매우 민감하게 변화한다. 수리학적 특성에서는 수심이나 유속 등의 흐름에 대한 분석이 있을 뿐 아니라, 유사이동에서의 침식이나 퇴적과 같은 하상변동도 중요하게 고려되어야 한다. 그러나, 지금까지 합류점에 내한 연구가 대부분 물의 흐름 해석에 관한 연구이며, 하상변화에 대한 연구가 상당히 부족하다. 본 실험 연구에서는 본류와 지류의 접근각도를 $60^{\circ},\;75^{\circ},\;90^{\circ}$로 변화시키면서 분석하였으며, 유량비는 1:0.2, 1:0.35, 1:0.5로 변화시키면서 분석하였다. 이때 사용한 모형수로는 본류와 지류의 폭을 1:0.8로 하였으며, 이동상 실험을 위해 입경 1mm인 균일 모래를 이용하여 실험하였다. 그 결과 침식되는 길이는 유량비 및 접근각도가 증가함에 따라 커지는 경향을 나타내고 있으며, 이는 합류부에서의 하상침식에 대한 개선방향으로 활용될 수 있을 것으로 판단되고 있으며, 또한 접근각도가 증가함에 따라서는 최심경사는 점차 증가하는 것으로 나타났으나, 유량비가 증가함에 따라 감소하는 것으로 나타났다.

• Journal of Korea Water Resources Association
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• v.31 no.5
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• pp.529-538
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• 1998

The flow configurations at open channel junctions are analyzed by 2-D depth averaged mathematical model. The governing factors of the flow at the junction are found to be discharge ratio between tributary flow and the post confluence combined flow, and confluence angle. Analyzed by these two factors are flow patterns and flow depth variation at the confluence, discharge ratio above which the flow upstresm from the junction is affected by the tributary flow and the geometries of a recirculation region. Further, the flow contraction in the downstream region and the deflection of the tributary flow in the main channel were investigated. The numerical results are compared with the existing experimental data fairly well.

• Water for future
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• v.23 no.4
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• pp.435-444
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• 1990

The flow characteristics varying with the rate of the radius of curvature to width (Rc/B) in open channel bends are investigated with a simplified numerical model, briefly. Secondary flow velocity and transverse bed slope are formulated from the equations of moment of momentum and force balance analysis, respectively. The conservation equations of mass and streamwise momentum are simplified by depth integration and its solution could be obtained form explicit finite difference method. Three sets of computer simulation are executed. The rates of Rc/B adopted in simulations are 2.7, 5.4, 8.1 , respectively. The terms analyzed in this paper are secondary flow velocity, streamwise velocity, the path of maximum streamwise velocity, deviation angle, and mass-shift velocity.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.38 no.2
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• pp.1-5
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• 2001

We propose an optical performance monitoring method for WDM optical transmission systems. By assigning a pair of AWG ports to each optical signal channel. the optical power, optical signal-to-noise ratio (OSNIO, and wavelength of all the signal channels are observed simultaneously. The output power ratio of the AWG port pair depended on the wavelength variation of the channel with sensitivity of 1dB/0.026nm. The OSNH results were deviated no more than 0.7dB from the results measured by optical signal analyzer (OSA).

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.10
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• pp.17-22
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• 2007

This paper presents a baseband complex bandpass filter for PHS applications with a new automatic tuning method. The full-CMOS PHS transceiver is implemented by adopting the Low-IF architecture to overcome the DCoffset problems. To meet the Adjacent Channel Selectivity (ACS) performance, the 3rd-order Chebyshev complex bandpass filter is designed as the baseband channel-select filter. The new corner frequency tuning method is proposed to compensate the process variation. This method can reduce the noise level due to MOS switches. The filter was fabricated using a 0.35{\mu}m$ CMOS process, and the power consumption is 12mW.

• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.2
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• pp.127-138
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• 2013

The impact of Empty Space layer in the channel region of a Double Gate (i.e. ESDG) MOSFET has been studied, by monitoring the DC, RF as well as the digital performance of the device using ATLAS 3D device simulator. The influence of temperature variation on different devices, i.e. Double Gate incorporating Empty Space (ESDG), Empty Space in Silicon (ESS), Double Gate (DG) and Bulk MOSFET has also been studied. The electrical performance of scaled ESDG MOSFET shows high immunity against Short Channel Effects (SCEs) and temperature variations. The present work also includes the linearity performance study in terms of $VIP_2$ and $VIP_3$. The proper bias point to get the higher linearity along with the higher transconductance and device gain has also been discussed.

• Water for future
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• v.29 no.3
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• pp.217-228
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• 1996

A new routing computer model for the symmetric compound channel called the ASFMCS (Apparent Shear Force Muskingum-Cung Method in Symmetry) is developed. The Muskingum-Cunge routing method is adapted. The Apparent Shear Force(ASF) between the deep main channel and shallow floodplain flow is introduced while the flow is routed. The nonlinear parameter method is applied. The temporal and spatial increments are varied according to the flow rate. The adaptation of above schemes is tested against the routed hydrographs using the DAMBRK model. The results of general routing practice of Muskingum-Cunge Method (GFMC) are also compared with those of the above two models. The results of the new model match remarkably well with those of DAMBRK. The routed hydrographs show smooth variation from the inflow boundary condition without any distortions caused by the difference of cross-section shape. However, the results of GPMC, showing earlier rising and falling of routed hydrograph, have considerable differences from those of the ASFMCS and DAMBRK.

• Journal of the Korean Society of Combustion
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• v.18 no.2
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• pp.1-7
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• 2013

Flame stabilization characteristics of premixed flames in narrow annular coaxial tubes (NACT) were investigated experimentally. The NACT burner was proposed as a model of a cylindrical refractory burner, and it was made of quartz tubes. Flame stabilization conditions affected by the characteristic length of the burner was investigated with the variation of the equivalence ratio and the flow rates. Flame behaviors in narrow spaces could be directly observed. Conclusively, more wide flame stabilization conditions could be obtained at the case of the decreased channel scale. A flame instability, such as combustion noise was detected concerned with the flame oscillation observed at the surface of multi channel stage. Some flame propagation characteristics had complicated tendencies that may exist in practical porous-media combustors. Therefore, this NACT burner can be a basic configuration for the development of flame stabilization model in porous media combustor, and it will enhance our understanding about the behavior of flames in meso-scale combustion spaces.