• Journal of Food Hygiene and Safety
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• v.15 no.2
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• pp.151-166
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• 2000

The subacute toxicity of xylooligosaccharide (XO) was evaluated in SD rats. Groups of 60 male and 60 female rats were orally administered with 0, 333, 1000 or 3000 mg/kg of XO for 13 weeks. The changes of body weight, food and water consumption were investigated for 17 weeks, while heamatological values and histopathological findings were investigated at the end of the 13 weeks and 17 weeks including 4 weeks of recovery periods. No death and toxic effects were observed during the test periods. There were statistically significant changes in several parameters, but these change had no direct relationship to dosage. Clinical changes were general occurrence and no specific toxicity was related to XO. Gross necropsy and histopathology revealed that no target organs were found in the treated mouse with XO. According to the results, no-observed effect level of XO is estimated to be above 3000 mg/kg.

• Tunnel and Underground Space
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• v.21 no.5
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• pp.370-376
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• 2011

To design the drainage system of a mine, it is very important to evaluate the groundwater inflow to the mine workings. In this study, continuous steady state flow through rock mass around mine openings developed in Sungok area of Gagok Mine was analyzed. Saturated only model and Saturated/unsaturated model were used as material models of rock mass. Groundwater quantities flowing into Sungok 160 level which is 1216 m long are computed as 1450 $m^3$/day in case of a saturated model and as 1071 $m^3$/day in case of a saturated/unsaturated model. An effect that hydraulic conductivity has on inflow turned out be greater than precipitation and inflow increased linearly with increase of hydraulic conductivity. It was found that change of hydraulic conductivity ratio and orientation have an impact on the variation of inflow and water table.

• Journal of the Korean Association of Geographic Information Studies
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• v.8 no.2
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• pp.136-144
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• 2005

GIS analyzes various topographic feature in three dimensions using triangulated irregular network (TIN). This paper proposed a method that can analyze topographic features effectively in three dimensions. Method developed in this study can calculate earth-volume, the inundation volume, storage volume etc, effectively. We could reduce error than existing volume calculation methods in computing volume in addition to water level's change about each. Also, the develop method can improve accuracy in measuring the storage of reservoirs. Main result of this paper id to develop a efficient calculation method using contour and elevation data on digital map.

• Journal of Biomedical Engineering Research
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• v.41 no.6
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• pp.228-234
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• 2020

Superparamagnetic iron oxide nanoparticles (SPIONs) are approved by the Food and Drug Administration (FDA) in the United States. SPIONs are used in magnetic resonance imaging (MRI) as contrast agents and targeted delivery in nanomedicine using external magnet sources. SPIONs act as an artificial peroxidase (i.e., nanozyme), and these reactions were highly stable in various pH conditions and temperatures. In this study, we report a nanozyme ability of the clustered SPIONs (CSPIONs) synthesized by the oil-in-water (O/W) method and coated with biocompatible poly(lactic-co-glycolic acid) (PLGA). We hypothesize that the CSPIONs can have high sensitivity toward H2O2 derived from the reaction between a fixed amount of glucose and glucose oxidase (GOX). As a result, CSPIONs oxidized a 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS) commonly used as a substrate for hydrogen peroxidase in the presence of H2O2, leading to a change in the color of the substrate. We also utilized a colorimetric assay at 417 nm using various glucose concentrations from 5 mM to 1.25 μM to validate β-D-glucose detection. This study demonstrated that the absorbance value increases along with increasing the glucose level. The results were highly repeated at concentrations below 5 mM (all standard deviations < 0.03). Moreover, the sensitivity and limit of detection were 1.50 and 5.44 μM, respectively, in which CSPIONs are more responsive to glucose than SPIONs. In conclusion, this study suggests that CSPIONs have the potential to be used for glucose detection in diabetic patients using a physiological fluid such as ocular, saliva, and urine.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.302-307
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• 2017

Draft ice in polar regions is formed due to sea level changes and various environmental factors cause damage due to collision with offshore plants and ships for resource development. Drift ice in polar regions is a potential source of accidents for offshore plants that perform long-term operations in one place, as well as on the ship. To prevent accidents with drift ice, offshore plants and ships in polar regions use satellite image information and detection radar to detect drift ice. However, the inability to use visible satellite images at night significantly lowers the detection probability by radar for small drift ice. In this study, we used a thermal imaging system which can be operated day and night for the detection of drift ice, and carried out an experimental study on the detection characteristics of drift ice. To examine the night operation of the thermal imaging system, the experimental condition was set and the thermal image was measured according to the measurement angle change. Under this condition, the correlation was analyzed by theoretical calculating the radiant energy of the drift ice and the sea water.

• Spatial Information Research
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• v.19 no.1
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• pp.61-72
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• 2011

Greenhouses gas emission due to usage of fossil fuel has been known as one of the main causes of global warming. Fundamentally, greenhouse gas is a by-product of economic activity. Since majority of economic activity happens in an urban setting, a countermeasure in an urban setting is needed. Therefore, an analysis of relationship between carbon dioxide emission and urban form will be investigated for urban planning and management in the future. The purpose of this study is to analyze the relationship between carbon dioxide emission and urban spatial patterns, and suggesting an urban form with low carbon dioxide emission. In order to achieve this, first theoretical analysis was carried out on urban spatial patterns related to physical size, usage rate, and activity level. Secondly, Seoul's dam on electricity, natural gas, local heating, petroleum, and water usage and mapping a carbon dioxide emission map. Thirdly, relationship between carbon dioxide emission and urban spatial patterns are analyzed and urban spatial patterns that affects energy usage in urban setting was elucidated, and elicited implications on future directions on urban planning based on our analyses above.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.5
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• pp.1192-1200
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• 2007

A general rainfall outflow in urban drainage has early time of concentration because urban drainage areas are most paved area. In general, rainfall outflow is flowed in drainage pump station and is discharged to rivers in urban areas. However it is excluded through drainage pumps about a heavy rainfall which exceed the design rainfall and the rainfall outflows increase the urban inundation risk. A current pump operation is control according to water level of collecting well or reservoir in drain pump station. But recently, the localized downpours are happened frequently in urban drainage and the current pump stations are frequently incapable of the heavy rainfall outflows. In this study, a real urban inundation was simulated and the drain capacity of drain pump station was evaluated by analysis about flood-factor in urban underground passage. Then the analysis about the inundation was done by the simulation about the real rainfall which cause the inundation. Also, in the simulation the inundation risk and the evaluation of flood-factor were analyzed according to change of the pump operation rule.

• Journal of Wetlands Research
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• v.8 no.4
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• pp.41-47
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• 2006

Global climatic changes are expected to influence various biogeochemical processes in wetland ecosystems. In particular, coastal mud flat is anticipated to be affected directly by temperature increase as well as indirectly by a sea level rise and changes in precipitation. This study aimed to determine changes in methane production under different temperature and salinity by employing a laboratory-scale manipulation experiment. Soil samples were collected from a mud flat in Dong-Gum Kang-Hwa island in winter and two types of experiments were conducted. In the first experiment soil samples at 0-5 cm, 5-10 cm depth were incubated under same salinity with pore water and diluted salinity to 50 % of natural condition for 20 days and methane production was measured every other days. In the second experiment, soil samples at 5-10 cm depth were incubated in different temperature, $5^{\circ}C$ and $15^{\circ}C$, under same salinity conditions with first experiment for 31 days and methane production was measured. Results of the first experiment revealed that higher amount of methane was produced at 5-10 cm depth, and salinity effect was predominant at the end of the experiment. The second experiment showed that methane production was higher in $15^{\circ}C$ than $5^{\circ}C$. In addition, methane production was higher when sea water diluted to 50 % compared to control. Global climatic changes are expected to influence various biogeochemical processes in wetland ecosystems. In particular, coastal mud flat is anticipated to be affected directly by temperature increase as well as indirectly by a sea level rise and changes in precipitation. This study aimed to determine changes in methane production under different temperature and salinity by employing a laboratory-scale manipulation experiment. Soil samples were collected from a mud flat in Dong-Gum Kang-Hwa island in winter and two types of experiments were conducted. In the first experiment soil samples at 0-5 cm, 5-10 cm depth were incubated under same salinity with pore water and diluted salinity to 50 % of natural condition for 20 days and methane production was measured every other days. In the second experiment, soil samples at 5-10 cm depth were incubated in different temperature, $5^{\circ}C$ and $15^{\circ}C$, under same salinity conditions with first experiment for 31 days and methane production was measured. Results of the first experiment revealed that higher amount of methane was produced at 5-10 cm depth, and salinity effect was predominant at the end of the experiment. The second experiment showed that methane production was higher in $15^{\circ}C$ than $5^{\circ}C$. In addition, methane production was higher when sea water diluted to 50 % compared to control. These results suggest that methane production is highly influenced by changes in temperature and salinity in coastal mud flat. And that global climatic change may induce biological feedback by affecting production of another greenhouse gas, namely methane from coastal mud flat.

• Journal of Korea Multimedia Society
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• v.12 no.11
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• pp.1629-1639
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• 2009

This paper describes the environmental monitoring system for supporting comfortable subways based on USN. Our development system includes the sensor field based on integrated sensor, monitoring system for supporting the local and remote monitoring and middle-ware performs the collecting, analyzing, and storing the data. In this paper, we installed the temperature, humidity, micro-dust sensor and water-level sensor for supporting the rail-roads and make up the integrated sensor enables to reuse the analog device from 4~20mA output with connection of wireless sensor device. Middleware includes the modules of collecting, analysis, and storing the data and monitoring system supports the local for administrator and remote monitoring for citizen services based on web. The middleware and monitoring in this paper is comprised of some components can reuse and support the change of application and sensors. Our development system supports the mobility of sensor devices and distributes system. Data collection and management function supported by middleware will use assessment.

• Journal of Korean Society on Water Environment
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• v.31 no.6
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• pp.599-609
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• 2015

In order to investigate why OSA (oxic-settling-anaerobic) process produces less sludge than CAS (conventional activated sludge) process, sequential cultivation through 1^st aerobic-anaerobic-2^nd aerobic conditions, were carried out. Then, the intracellular concentrations of adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD and NADH), and nicotinamide adenine dinucleotide phosphate (NADP and NADPH) were monitored for these three stages. Results showed that the concentrations of these energy substances rapidly decreased through time in both aerobic and anaerobic conditions but the anaerobic culture contained the lower energy level than aerobic culture. The 2^nd aerobic culture that experienced anaerobic condition showed lower concentration of these energy substances than those of the 1^st aerobic culture. Meanwhile, the anaerobic culture corresponding to the sludge holding stage of OSA was subjected to different soluble chemical oxygen demand (SCOD) levels, detention time, and temperature to evaluate the effects of these variations on the energy level difference between the 1^st and 2^nd aerobic stages. The lower the SCOD concentration, the longer detention time; and the higher temperature in the anaerobic stage tended to further reduce the intracellular level of the 2^nd aerobic culture. On the average, the intracellular energy level of the anaerobic and 2^nd aerobic stage were 57.73% and 39.12% of the 1st aerobic culture, respectively. These indicated that the insertion of an anaerobic stage between two aerobic stages could lower the intracellular energy levels, hence the lower the sludge in OSA than CAS process. Moreover, manipulation of the operating conditions of the intervening anaerobic stage can change intracellular energy levels thereby controlling sludge production.