• Tunnel and Underground Space
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• v.16 no.3 s.62
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• pp.218-231
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• 2006

Anisotropic/heterogeneous rock mass shows various deformation behavior types due to tunnelling because deformation behavior is largely controlled by the spacial characteristics of geological factors such as faults, joints and fractured zone in rock mass. In this paper 2-dimensional numerical analysis on the several influencing factors is performed considering fractured zone located near tunnel. This numerical analysis shows that deformation behavior of tunnel are very different according to the width and the location of fractured zone and supper method. However, 3-dimensional analysis is necessary to consider 3-dimensional geometrical characteristics sufficiently since discontinuity and fractured zone have 3-dimensional geometry. Also flexible design/construction guidelines for tunnelling are required to cope with uncertain ground condition and circumstance for technically safe and economic tunnel construction.

• Toxicological Research
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• v.30 no.4
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• pp.267-276
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• 2014

Exposures to lead (Pb) are associated with neurological problems including psychiatric disorders and impaired learning and memory. Pb can be absorbed by iron transporters, which are up-regulated in hereditary hemochromatosis, an iron overload disorder in which increased iron deposition in various parenchymal organs promote metal-induced oxidative damage. While dysfunction in HFE (High Fe) gene is the major cause of hemochromatosis, the transport and toxicity of Pb in Hfe-related hemochromatosis are largely unknown. To elucidate the relationship between HFE gene dysfunction and Pb absorption, H67D knock-in Hfe-mutant and wild-type mice were given drinking water containing Pb 1.6 mg/ml ad libitum for 6 weeks and examined for behavioral phenotypes using the nestlet-shredding and marble-burying tests. Latency to nestlet-shredding in Pb-treated wild-type mice was prolonged compared with non-exposed wild-types (p < 0.001), whereas Pb exposure did not alter shredding latency in Hfe-mutant mice. In the marble-burying test, Hfe-mutant mice showed an increased number of marbles buried compared with wild-type mice (p = 0.002), indicating more repetitive behavior upon Hfe mutation. Importantly, Pb-exposed wild-type mice buried more marbles than non-exposed wild-types, whereas the number of marbles buried by Hfe-mutant mice did not change whether or not exposed to Pb. These results suggest that Hfe mutation could normalize Pb-induced behavioral alteration. To explore the mechanism of repetitive behavior caused by Pb, western blot analysis was conducted for proteins involved in brain dopamine metabolism. The levels of tyrosine hydroxylase and dopamine transporter increased upon Pb exposure in both genotypes, whereas Hfe-mutant mice displayed down-regulation of the dopamine transporter and dopamine D1 receptor with D2 receptor elevated. Taken together, our data support the idea that both Pb exposure and Hfe mutation increase repetitive behavior in mice and further suggest that these behavioral changes could be associated with altered dopaminergic neurotransmission, providing a therapeutic basis for psychiatric disorders caused by Pb toxicity.

• Journal of the Korean Institute of Gas
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• v.27 no.4
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• pp.27-33
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• 2023

In a petrochemical plant, various mechanical equipments and structures are interconnected to ensure operability. Since the production activities of petrochemical plants have a great impact on the national economy, it is very important to maintain not only structural safety but also the operability of the facilities. However, the current seismic design standards present the design requirements of facilities mainly aimed at preventing collapse, and do not provide the requirements for securing operability of facilities. Depending on the behavioral characteristics of the facility, operability of the facility can be secured by seismic performance levels other than the collapse prevention level, so it is necessary to present seismic design methods that can apply various seismic performance levels. Spherical (ball) storage tanks are supported by columns and braces and exhibit complex nonlinear behavior because of buckling and yielding of support members. In this study, nonlinear seismic behavior characteristics were statistically analyzed and a new performance-based seismic design method was proposed based on them.

• Journal of Computing Science and Engineering
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• v.2 no.2
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• pp.200-219
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• 2008

The effective management of uncertainty is one of the most fundamental problems in medical decision making. According to the literatures review, most medical decision models rely on point estimates for input parameters. However, it is natural that they should be interested in the relationship between changes in those values and subsequent changes in model output. Therefore, the purpose of this study is to identify the ranges of numerical values for which each option will be most efficient with respect to the input parameters. The Nonhomogeneous Poisson Process(NHPP) was used for describing the behavior of aging chronic diseases. Three kind of failure models (linear, exponential, and power law) were considered, and each of these failure models was studied under the assumptions of unknown scale factor and known aging rate, known scale factor and unknown aging rate, and unknown scale factor and unknown aging rate, respectively. In addition, this study illustrated developed method with an analysis of data from a trial of immunotherapy in the treatment of chronic Granulomatous disease. Finally, the proposed design of Bayesian value of information analysis facilitates the effective use of the computing capability of computers and provides a systematic way to integrate the expert's opinions and the sampling information which will furnish decision makers with valuable support for quality medical decision making.

• Journal of the Ergonomics Society of Korea
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• v.18 no.3
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• pp.141-152
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• 1999

In this paper, We performed the human body dynamic modelling for the realistic animation based on the dynamical behavior of human body, and designed controller for the effective control of complicate human dynamic model. The human body was simplified as a rigid body which consists of 18 actuated degrees of freedom for the real time computation. Complex human kinematic mechanism was regarded as a composition of 6 serial kinematic chains : left arm, right arm, support leg, free leg, body, and head. Based on the this kinematic analysis, dynamic model of human body was determined using Newton-Euler formulation recursively. The balance controller was designed in order to control the nonlinear dynamics model of human body. The effectiveness of designed controller was examined by the graphical simulation of human walking motion. The simulation results were compared with the model base control results. And it was demonstrated that, the balance controller showed better performance in mimicking the dynamic motion of human walking.

• Journal of Korean Institute of Industrial Engineers
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• v.31 no.2
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• pp.173-179
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• 2005

This paper presents an extended EMQ model which determines an optimal production quantity for a single stage production system when defective items are stochastically produced in the production process and they are re-processed in the rework process to convert them into non-defectives. Through the mathematical modeling, an optimal solution minimizing the average cost per unit time and minimum average cost as well as some properties are derived. It can be shown that each of the existing models is a special case of the proposed model under some conditions. Numerical experiment is carried out to examine the behavior of the proposed model and support properties derived.

• Nuclear Engineering and Technology
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• v.41 no.6
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• pp.831-840
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• 2009

In order to evaluate the start-up behavior and to identify, through abnormal operation occurrences, the transient behaviors of the Sulfur Iodine(SI) process, which is a nuclear hydrogen process that is coupled to a Very High Temperature Gas Cooled Reactor (VHTR) through an Intermediate Heat Exchanger (IHX), a dynamic simulation of the process is necessary. Perturbation of the flow rate or temperature in the inlet streams may result in various transient states. An understanding of the dynamic behavior due to these factors is able to support the conceptual design of the secondary helium loop system associated with a hydrogen production plant. Based on the mass and energy balance sheets of an electrodialysis-embedded SI process equivalent to a 200 $MW_{th}$ VHTR and a considerable thermal pathway between the SI process and the VHTR system, a dynamic simulation of the SI process was carried out for a sulfuric acid decomposition process (Second Section) that is composed of a sulfuric acid vaporizer, a sulfuric acid decomposer, and a sulfur trioxide decomposer. The dynamic behaviors of these integrated reactors according to several anticipated scenarios are evaluated and the dominant and mild factors are observed. As for the results of the simulation, all the reactors in the sulfuric acid decomposition process approach a steady state at the same time. Temperature control of the inlet helium is strictly required rather than the flow rate control of the inlet helium to keep the steady state condition in the Second Section. On the other hand, it was revealed that the changes of the inlet helium operation conditions make a great impact on the performances of $SO_3$ and $H_2SO_4$ decomposers, but no effect on the performance of the $H_2SO_4$ vaporizer.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.12 no.4
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• pp.121-131
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• 2017

The most important points in the field of entrepreneurship research are new venture creation and behaviors for start-up venture. Most of past researches are limited to the formation of entrepreneurial intention, and researches on entrepreneurial activities, specifically nascent entrepreneurial behavior, have not been studied well. In this study, we view entrepreneurial process as gestation process from entrepreneurial intention to nascent entrepreneurial activities, and identify the moderating effects of cognitive style, which is the way of thinking about the information in entrepreneurial process. In addition, we find the moderating effects of cognitive style on the relationships between perceived barriers and support in environmental factors and nascent entrepreneurial activities. Subjects of this study are potential entrepreneurs. So we selected university students who are taking venture start-up course, conducted a survey, collected 367 questionnaires. In statistical test, we applied PLS-SEM for testing hypotheses because CB-SEM is too sensitive to test more than two moderating effects in th research model. As a result of the analysis, it was found that entrepreneurial intention, cognitive planning style, cognitive creative style, perceived support had a significant effect on nascent entrepreneurial behavior. The results of the analysis of the moderating effects of cognitive style which are the hypotheses in the research are as follows. First, the cognitive planning style did not have a significant moderating effect on the relationship between entrepreneurial intention and nascent entrepreneurial activities. Second, in the relationship between perceived barriers and nascent entrepreneurial activity, cognitive planning style did not have significant moderating effect, and cognitive creating style had significant negative moderating effect. Third, in the relationship between perceive support and nascent entrepreneurial activity, cognitive planning style had significant positive moderating effect, and cognitive creating style did not have significant moderating effect.

• The Journal of the Korea Contents Association
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• v.10 no.3
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• pp.271-281
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• 2010

Background: This research has been carried out to analyze presupposition factors which influence factors on Rehabilitation Exercise practice in Elderly limited Activities of Daily-Living an Anlaysis based on Theory of Planned Behavior to support to induce Rehabilitation Exercise behavior. Method: From the geriatric hospitals in Pusan and Kyungnam, 316 elderly who has ADL Disability participated in the study. We did 1st questionnaire investigation. We provided them 4 weeks of Rehabilitation Exercise training, and 2 weeks later we collected 2nd questionnaire sheet to confirm their Rehabilitation Exercise behavior practice and analysed. Results: In this research relative influence to behavioral intention for Rehabilitation Exercise headed by attitude toward the behavior(.61), perceived behavior control(-.56) and subjective norm(.27)these results were slightly different from other research, in case of perceived behavior control was low but on attitude toward the behavior it showed high in results. It's older have strong subjectivities and has not change their mind, the old's behavioral intention is expressed as an attitude toward the behavior. Rehabilitation Exercise Practice of Elder should prioritize to have the health belief which is positive, As a result it will be regarded to expect the maximum effect.

• Korean Journal of School Psychology
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• v.15 no.3
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• pp.399-431
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• 2018

The purpose of this study was to summarize the empirical literature on implementation of positive behavior support (PBS) within a multi-tiered system of supports in American and Korean schools and to compare its key features and outcomes in an attempt to suggest future directions for development of a Korean school-wide PBS model and implementation manuals as well as directions for future research. Twenty-four American articles and 11 Korean articles (total 35 articles) that reported the outcomes of implementation of PBS at a tier 1 and/or tier 2, or tier 3 level and that met established inclusion criteria were analyzed using systematic procedures. Comparisons were made in the areas of key features and outcomes of PBS in addition to general methodology (e.g., participants, design, implementation duration, dependent measures) at each tier of PBS. The results indicated that positive outcomes for student behavior and other areas were reported across tiers in all American and Korean studies. At the tier 1 level, teaching expectations and rules were the primary focus of PBS in American and Korean schools. However, Korean schools focused on modifying the school and classroom environments and teaching social skills whereas American schools focused on teacher training on standardized interventions or curricular by experts and teacher support during implementation of PBS. At the tier 2 level, more American studies reported implementation of tier 2 interventions within school-wide PBS, and Check/In Check/Out (CICO) was found to be the most commonly used tier 2 intervention. The results also indicated that in comparison to Korean schools, American schools were more likely to use systematic screening tools or procedures to identify students who need tier 2 interventions and more likely to promote parental involvement with implementing interventions. At the tier 3 level, more Korean studies reported the outcomes of individualized interventions, but more American studies reported that designing individualized intervention plans based on comprehensive functional behavior assessment results and establishment of systematic screening systems were focused when implementing individualized interventions. Furthermore, few Korean studies reported the assessment of procedural integrity, social validity, and contextual fit in implementing PBS across tiers, indicating the need for development of valid instruments that could be used in assessing these areas. Based on these results, limitations of the study and suggestions for future research are discussed.