• Applied Biological Chemistry
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• v.49 no.1
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• pp.65-69
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• 2006

With extracted Aloe vera and Aloe arborescens, anti-inflammatory effect was examined in phosphatidic acid-stimulated Raw 264.7 cells. Phosphatidic acid $(50\;{\mu}g/ml)$ treatment increased inflammation related 264.7 cells. The extracts of $80\;{\mu}g/ml$ concentration from Aloe arborescens reduced the expression of iNOS. Aloe vera and Aloe arborescens also reduced the expression of COX-2, it seems that anti-inflammatory effects of Aloe extracts is partly due to the inhibition of COX-2 expression by inhibiting in Raw 264.7 cells.

• Journal of Pharmaceutical Investigation
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• v.35 no.5
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• pp.343-348
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• 2005

Recently, siRNA has been emerging as new therapeutic agents for various diseases such as cancers and infectious diseases. However, the evaluation for delivery systems for siRNA has not been fully done. In this study, we designed and delivered siRNA of oncogenic E6 and E7 proteins to several cell lines and tested the delivery efficiencies of various cationic nonviral delivery vectors. Of cationic delivery systems tested in this study, lipid-based Lipofectamine revealed higher delivery efficiency of siRNA to cervical cancer cell line, SiHa, compared to other delivery systems. Notably, the polyethylenimine, which showed the comparable delivery efficiencies in plasmid DNA, did not show significant delivery of siRNA in cervical cancer cells. These results indicate that the mechanisms involved in siRNA delivery might be different from those in plasmid DNA delivery, and that cationic lipid-based delivery vehicles deliver siRNA with higher efficiency to intracellular target sites.

• Journal of The Korean Society of Agricultural Engineers
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• v.51 no.6
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• pp.69-76
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• 2009

Soils exhibit creep behavior in which deformation and movement proceed under a state of constant stress or load. In Korea, weathered soil is abundant and occupies around one-third of the country. Weathered soil is visually described as a sandy or gravelley soil, but the behavior is quite different from the behavior of usual sand and gravel. In particular, the permeability of weathered soil is similar to sand, but the durability of settlement is similar to clay. Therefore analysis of time-dependent behavior of weathered soil is very important. In this study, Creep tests with weathered soils were carried out under constant principal stress differences of various stress levels which were experimentally obtained by triaxial compression test. The results of these tests showed the creep behavior for which the deformation increased with time, and the results are consistent with phenomenological model by creep equation of Singh-Mitchell.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.8B
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• pp.624-629
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• 2008

Many routing protocols have been proposed for sensor networks where energy awareness and reliability are essential design issues. This paper proposes an Energy-aware Tree Routing Protocol (ETRP) for Wireless Sensor Networks. The proposed scheme relates to reliable and energy efficient data routing by selecting a data transmission path in consideration of residual energy at each node to disperse energy consumption across the networks and reliably transmit the data through a detour path when there is link or node failure. Simulation results show that the proposed method outperformed traditional Tree Routing (TR) by 23.5% in network lifetime.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.05a
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• pp.151-151
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• 2007

• Journal of Chest Surgery
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• v.42 no.4
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• pp.528-531
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• 2009

Transesophageal echocardiography (TEE) is widely used to evaluate the heart function and the result of surgery during a cardiac operation. The incidence of complications associated with TEE is low, yet critical complications such as lower pharyngeal injury and esophageal perforation may happen. We report hereon a case of 77-year old male patient who suffered from injury to the pyriform sinus and concurrent deep neck infection after off pump coronary artery bypass surgery and intraoperative TEE.

• Journal of The Korean Astronomical Society
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• v.44 no.3
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• pp.81-87
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• 2011

We carry out 100-GHz band test observations with the newly-constructed KVN 21-m radio telescopes in order to evaluate their performance. The three telescopes have similar performance parameters. The pointing accuracies are about 4" rms for the entire sky. The main beam sizes are about 30" (FWHMs), which is nearly the diffraction limit of the telescopes at the observing frequency (97 GHz). The measured aperture and main-beam efficiencies are about 52% and 46%, respectively, for all three telescopes. The estimated moon efficiency is ~84% for the KVN Tamna telescope. The first sidelobes appear 50" (~1.6${\times}$FWHM) from the main beam centers and the levels are on average -14 dB.

• Journal of The Korean Astronomical Society
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• v.47 no.6
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• pp.255-258
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• 2014

Using sunspot number data from 270 historical stations for the period 1981-2013, we investigate their personal reduction coefficients (k) statistically. Chang & Oh (2012) perform a simulation showing that the k varies with the solar cycle. We try to verify their results using observational data. For this, a weighted mean and weighted standard deviation of monthly sunspot number are used to estimate the error from observed data. We find that the observed error (noise) is much smaller than that used in the simulation. Thus no distinct k-variation with the solar cycle is observed contrary to the simulation. In addition, the probability distribution of k is determined to be non-Gaussian with a fat-tail on the right side. This result implies that the relative sunspot number after 1981 might be overestimated since the mean value of k is less than that of the Gaussian distribution.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.1 s.256
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• pp.70-76
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• 2007

Elastic-plastic fracture mechanics is popularly used for integrity evaluation of major components, however, it is not easy to extract standard specimens from operating facility. This paper examines how ductile fracture toughness is characterized by a small punch testing technique in conjunction with finite element analyses incorporating a damage model. At first, micro-mechanical parameters constituting Rousselier model are calibrated for typical nuclear materials using both estimated and experimental load-displacement (P-$\delta$) curves of miniaturized specimens. Then, fracture resistance (J-R) curves of relatively larger standard CT specimens are predicted by finite element analyses employing the calibrated parameters and compared with corresponding experimental ones. It was proven that estimated results by the proposed method using small punch specimen is promising and might be used as a useful tool for ductile crack growth evaluation.

• Clean Technology
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• v.23 no.3
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• pp.314-324
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• 2017

To verify the viability of Co, Ru and Zr-based catalyst for $CO_2$ (dry) reforming reaction, catalysts were fabricated using cordierite, silicon carbide and rota monolithic substrates, and they were compared with the conventional $Co-Ru-Zr/SiO_2$ catalyst in terms of performance and durability. Cordierite monolith was showed high activity with the least amount of active component. In addition, when Cordierite monolith was coated with Co-Ru-Zr in various ways, most excellent performance was showed at a precursor solution coating method. In particular, when 0.9 wt% Co-Ru-Zr/Cordierite was used for reaction, it was observed that 95% $CO_2$ conversion was maintained for 300 h at $900^{\circ}C$.