• Title/Summary/Keyword: Chain safety

Search Result 622, Processing Time 0.041 seconds

A Study on the Improvement of Competitive Power of Small and Medium Export Business through using the BPO and SCF (BPO·공급망금융의 이용을 통한 중소수출기업의 경쟁력 제고방안에 관한 연구)

  • Jang, Eun-Hee;Hwang, Jee-Hyon
    • Korea Trade Review
    • /
    • v.42 no.5
    • /
    • pp.233-252
    • /
    • 2017
  • The fast changes of global financial environment in recent years increase the risk of trade settlement. This means are required to minimize risk of non payment and to maximize secure payment. Open Account trade accounts for 90% of global trade flows. The O/A system means that the goods, along with all the necessary documents, are shipped and delivered before payment is due, usually within a time frame from 30 to 90 days. Meanwhile, Korean small and medium-sized export enterprises are compelled to globalize their activities owing to limitation and competitiveness of domestic marketplace. To keep face with the global trade settlement system and to support globalization of small and medium-sized export firms, the BPO together with Supply Chain Finance will be solutions. The introduction of the BPO system will allow banks to broaden O/A offerings to their client base and due to secure safety, sellers could ship the goods without delay according to orders and buyers could settle promptly by payment undertaking of correspondent banks. Therefore, it is more effective for companies which have sustainable customers and stable transaction. This study take a look at the trend of the global payment systems and suggested limitation of existed payment in order to derive improvement measures of electronic payment for small and medium-sized export enterprises.

  • PDF

Characterization of Thermal Degradation of Polymide 66 Composite: Relationship between Lifetime Prediction and Activation Energy (폴리아미드 66 복합소재의 열 열화 특성: 수명 예측과 활성화 에너지의 상관관계)

  • Jung, Won-Young;Weon, Jong-Il
    • Polymer(Korea)
    • /
    • v.36 no.6
    • /
    • pp.712-720
    • /
    • 2012
  • Thermal degradation for glass fiber-reinforced polyamide 66 composite (PA 66) with respect of thermal exposure time has been investigated using optical microscopy, scanning electron microscopy and Fourier transform infrared spectroscopy. As the thermal exposure time was prolonged, a slight increase in tensile strength for only initial stage and afterward, a proportional decrease of tensile strength was observed. These results can be explained by the increase of crystallinity, followed by the increase of crosslinking density, chain scission and the decrease in chain mobility, due to thermal oxidation with the exposure time. Fourier transform infrared spectroscopy results showed the increase of ketone peak and silica peak on the surface of thermally exposed PA 66. In addition, the thermal decomposition kinetics of PA 66 was analyzed using thermogravimetric analysis at three different heating rates. The relationship between activation energy and lifetime-prediction of PA 66 was investigated by several methodologies, such as statistical tool, UL 746B, Ozawa and Kissinger. The activation energy determined by thermogravimetric analysis had a relatively large value compared with that from the accelerated test. This may result in over-estimating the lifetime of PA 66. In this study, a master curve of exponential fitting has been developed to extrapolate the activation energy at various service temperatures.

Effect of all-trans retinoic acid on casein and fatty acid synthesis in MAC-T cells

  • Liao, Xian-Dong;Zhou, Chang-Hai;Zhang, Jing;Shen, Jing-Lin;Wang, Ya-Jing;Jin, Yong-Cheng;Li, Sheng-Li
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.33 no.6
    • /
    • pp.1012-1022
    • /
    • 2020
  • Objective: Caseins and fatty acids of milk are synthesized and secreted by the epithelial cells of the mammary gland. All-trans retinoic acid (ATRA), an active metabolite of vitamin A, has been shown to promote mammary development. This study was conducted to determine the effect of ATRA on casein synthesis and fatty acid composition in MAC-T cells. Methods: MAC-T cells were allowed to differentiate for 4 d, treated with ATRA (0, 1.0, 1.5, and 2.0 μM), and incubated for 3 d. We analyzed the fatty acid composition, the mRNA expression of casein and fatty acid synthesis-related genes, and the phosphorylation of casein synthesis-related proteins of MAC-T cells by gas chromatography, quantitative polymerase chain reaction, and western blotting, respectively. Results: In MAC-T cells, ATRA increased the mRNA levels of αS1-casein and β-casein, janus kinase 2 (JAK2) and E74-like factor 5 of the signal transducer and activator of transcription 5 β (STAT5-β) pathway, ribosomal protein S6 kinase beta-1 (S6K1) and eukaryotic translation initiation factor 4E binding protein 1 of the mammalian target of rapamycin (mTOR) pathway, inhibited the mRNA expression of phosphoinositide 3-kinase and eukaryotic initiation factor 4E of the mTOR pathway, and promoted the phosphorylation of STAT5-β and S6K1 proteins. Additionally, ATRA increased the de novo synthesis of fatty acids, reduced the content of long-chain fatty acids, the ratio of monounsaturated fatty acids to saturated fatty acids (SFA), the ratio of polyunsaturated fatty acids (PUFA) to SFA, and the ratio of ω-6 to ω-3 PUFA. The mRNA levels of acetyl-CoA carboxylase 1, fatty acid synthase, lipoprotein lipase, stearoyl-CoA desaturase, peroxisome proliferator-activated receptor gamma, and sterol regulatory element-binding protein 1 (SREBP1) were enhanced by ATRA. Conclusion: ATRA promotes the synthesis of casein by regulating JAK2/STAT5 pathway and downstream mTOR signaling pathway, and it improves the fatty acid composition of MAC-T cells by regulating SREBP1-related genes.

Estimating the compound risk integrated hydrological / hydraulic / geotechnical uncertainty of levee systems (수문·수리학적 / 지반공학적 불확실성을 고려한 제방의 복합위험도 산정)

  • Nam, Myeong Jun;Lee, Jae Young;Lee, Cheol Woo;Kim, Ki Young
    • Journal of Korea Water Resources Association
    • /
    • v.50 no.4
    • /
    • pp.277-288
    • /
    • 2017
  • A probabilistic risk analysis of levee system estimates the overall level of flood risk associated with the levee system, according to a series of possible flood scenarios. It requires the uncertainty analysis of all the risk components, including hydrological, hydraulic and geotechnical parts computed by employing MCMC (Markov Chain Monte Carlo), MCS (Monte Carlo Simulation) and FOSM (First-Order Second Moment), presents a joint probability combined each probability. The methodology was applied to a 12.5 km reach from upstream to downstream of the Gangjeong-Goryeong weir, including 6 levee reaches, in Nakdong river. Overtopping risks were estimated by computing flood stage corresponding to 100/200 year high quantile (97.5%) design flood causing levee overflow. Geotechnical risks were evaluated by considering seepage, slope stability, and rapid drawdown along the levee reach without overflow. A probability-based compound risk will contribute to rising effect of safety and economic aspects for levee design, then expect to use the index for riverside structure design in the future.

Development and Validation of an Analytical Method for Determination of Fungicide Benzovindiflupyr in Agricultural Commodities Using LC-MS/MS (LC-MS/MS를 이용한 농산물 중 살균제 벤조빈디플루피르의 잔류시험법 개발 및 검증)

  • Lim, Seung-Hee;Do, Jung-Ah;Park, Shin-Min;Pak, Won-Min;Yoon, Ji Hye;Kim, Ji Young;Chang, Moon-Ik
    • Journal of Food Hygiene and Safety
    • /
    • v.32 no.4
    • /
    • pp.298-305
    • /
    • 2017
  • Benzovindiflupyr is a new pyrazole carboxamide fungicide that inhibits succinate dehydrogenase of mitochondrial respiratory chain. This study was carried out to develop an analytical method for the determination of benzovindiflupyr residues in agricultural commodities using LC-MS/MS. The benzovindiflupyr residues in samples were extracted by using acetonitrile, partitioned with dichloromethane, and then purified with silica solid phase extraction (SPE) cartridge. Correlation coefficient ($r^2$) of benzovindiflupyr standard solution was 0.99 over the calibration ranges ($0.001{\sim}0.5{\mu}g/mL$). Recovery tests were conducted on 5 representative agricultural commodities (mandarin, green pepper, potato, soybean, and hulled rice) to validate the analytical method. The recoveries ranged from 79.3% to 110.0% and then relative standard deviation (RSD) was less than 9.1%. Also the limit of detection (LOD) and limit of quantification (LOQ) were 0.0005 and 0.005 mg/kg, respectively. The recoveries of interlaboratory validation ranged from 83.4% to 117.3% and the coefficient of variation (CV) was 9.0%. All results were followed with Codex guideline (CAC/GL 40) and Ministry of Food and Safety guideline (MFDS, 2016). The proposed new analytical method proved to be accurate, effective, and sensitive for benzovindiflupyr determination and would be used as an official analytical method.

Performance-based wind design of tall buildings: concepts, frameworks, and opportunities

  • Bezabeh, Matiyas A.;Bitsuamlak, Girma T.;Tesfamariam, Solomon
    • Wind and Structures
    • /
    • v.31 no.2
    • /
    • pp.103-142
    • /
    • 2020
  • One of the next frontiers in structural wind engineering is the design of tall buildings using performance-based approaches. Currently, tall buildings are being designed using provisions in the building codes and standards to meet an acceptable level of public safety and serviceability. However, recent studies in wind and earthquake engineering have highlighted the conceptual and practical limitations of the code-oriented design methods. Performance-based wind design (PBWD) is the logical extension of the current wind design approaches to overcome these limitations. Towards the development of PBWD, in this paper, we systematically review the advances made in this field, highlight the research gaps, and provide a basis for future research. Initially, the anatomy of the Wind Loading Chain is presented, in which emphasis was given to the early works of Alan G. Davenport. Next, the current state of practice to design tall buildings for wind load is presented, and its limitations are highlighted. Following this, we critically review the state of development of PBWD. Our review on PBWD covers the existing design frameworks and studies conducted on the nonlinear response of structures under wind loads. Thereafter, to provide a basis for future research, the nonlinear response of simple yielding systems under long-duration turbulent wind loads is studied in two phases. The first phase investigates the issue of damage accumulation in conventional structural systems characterized by elastic-plastic, bilinear, pinching, degrading, and deteriorating hysteretic models. The second phase introduces methods to develop new performance objectives for PBWD based on joint peak and residual deformation demands. In this context, the utility of multi-variate demand modeling using copulas and kernel density estimation techniques is presented. This paper also presents joined fragility curves based on the results of incremental dynamic analysis. Subsequently, the efficiency of tuned mass dampers and self-centering systems in controlling the accumulation of damage in wind-excited structural systems are investigated. The role and the need for explicit modeling of uncertainties in PBWD are also discussed with a case study example. Lastly, two unified PBWD frameworks are proposed by adapting and revisiting the Wind Loading Chain. This paper concludes with a summary and a proposal for future research.

Seismic Reliability Analysis of Offshore Wind Turbine with Twisted Tripod Support using Subset Simulation Method (부분집합 시뮬레이션 방법을 이용한 꼬인 삼각대 지지구조를 갖는 해상풍력발전기의 지진 신뢰성 해석)

  • Park, Kwang-Yeun;Park, Wonsuk
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • v.32 no.2
    • /
    • pp.125-132
    • /
    • 2019
  • This paper presents a seismic reliability analysis method for an offshore wind turbine with a twisted tripod support structure under earthquake loading. A three dimensional dynamic finite element model is proposed to consider the nonlinearity of the ground-pile interactions and the geometrical characteristics of the twisted tripod support structure where out-of-plane displacement occurs even under in-plane lateral loadings. For the evaluation of seismic reliability, the failure probability was calculated for the maximum horizontal displacement of the pile head, which is calculated from time history analysis using artificial earthquakes for the design return periods. The application of the subset simulation method using the Markov Chain Monte Carlo(MCMC) sampling is proposed for efficient reliability analysis considering the limit state equation evaluation by the nonlinear time history analysis. The proposed method can be applied to the reliability evaluation and design criteria development of the offshore wind turbine with twisted tripod support structure in which two dimensional models and static analysis can not produce accurate results.

Designing an evaluation model for cyber security management system implementation for companies participating in the automobile supply chain (based on ISO/SAE 21434 standard and TISAX assessment requirements) (자동차 공급망 참여기업 대상 사이버보안 관리체계 구현 평가모델설계 (ISO/SAE 21434 표준 및 TISAX 평가 요구사항을 기반으로))

  • Baek Eun Ho
    • Convergence Security Journal
    • /
    • v.22 no.5
    • /
    • pp.49-59
    • /
    • 2022
  • Cyber security in the automobile sector is a key factor in the life cycle of automobiles, and cyber security evaluation standards are being strengthened worldwide. In addition, not only manufacturers who design and produce automobiles, but also due to the nature of automobiles consisting of complex components and various parts, the safety of cybersecurity can be secured only when the implementation level of the cybersecurity management system of companies participating in the entire supply chain is evaluated and managed. In this study, I analyzed the requirements of ISO/SAE 21434 and TISAX, which are representative standards for evaluating automotive cybersecurity. Through a survey conducted on domestic/overseas company security officers and related experts, suitability and feasibility were reviewed according to priorities and industries, so 6 areas and 45 evaluation criteria were derived and presented as final evaluation items. This study is meaningful as a study in that it presented a model that allows companies participating in the automotive supply chain to evaluate the current cybersecurity management level of the company by first applying ISO/SAE 21434 and TISAX overall control processes before uniformly introducing them.

Evaluation of a PCR Assay for the Rapid Detection of Staphylococcus aureus in Milk and Meat Products (유제품과 육제품에서 황색포도상구균 신속검출을 위한 PCR법의 비교검증)

  • Kim, Hong-Seok;Chon, Jung-Whan;Kim, Dong-Hyeon;Song, Kwang-Young;Seo, Kun-Ho
    • Korean Journal of Food Science and Technology
    • /
    • v.45 no.6
    • /
    • pp.791-795
    • /
    • 2013
  • The aim of this study was to compare the performance of a standard culture method and polymerase chain reaction (PCR) for the detection of Staphylococcus aureus (S. aureus) in milk and meat products. Milk, dried infant formula, sausage and ground beef that had been artificially inoculated with S. aureus were enriched in tryptic soy broth. After the enrichment, a loopful was inoculated onto Baird-Parker agar with egg-yolk-tellurite. In parallel, 23S rRNA was amplified by PCR from samples of the enriched broth. Suspected S. aureus colonies grown on selective agars were finally confirmed by a coagulase test and colony PCR. No significant statistical differences were observed between the incidence of S. aureus detected by the culture method and the incidence detected by PCR, in milk or dried infant formula. However, in sausage and ground beef, the number of positives detected by PCR was significantly higher than by the culture method (p<0.05). Our findings suggest that PCR could be an effective screening tool for the detection of S. aureus compared to the standard culture method.

Enhancement of Immune Response by New Herb Mixture, APA-01, in Mice (한방혼합액 APA-01의 면역 증강 효과)

  • Lee Young Sun;Han Ok Kyung;Park Chan Woo;Jeon Tae Won;Lee Eun Sil;Shin Sang Woo;Kim Kwang Joong;Kim Hyo Jung
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.16 no.3
    • /
    • pp.483-489
    • /
    • 2002
  • APA-01, which is an aqueous extract of five Chinese herbs, is a modified formula of Huoxiang-Zhengqi-San. The effect of new herb extract on immune response was investigated. The parameter examined to assess apparent immune response of APA-01 in mice included changes of body weight, relative weight of immune organs, cell proliferation and cytokine gene expression. The body weight and relative weight of immune organs were not significantly changed among the tested groups. In the spleen cell prolijeration assay, APA-01 increased the cell proliferation in a dose-dependent manner. Methotrexate (MTX), an agent of immune suppression, inhibited the spleen cell proliferation (IC/sub 50/: 800㎍/㎖). However, APA-01 significantly inhibited the suppression of mouse spleen cell proliferation. Therefore, it seems that APA-01 has a reducing effect of immune suppression. Immunomodulatory effect of APA-01 was further investigated using reverse transcription polymerase chain reaction (RT-PCR) in mouse spleen cells. In RT-PCR test, APA-01 enhanced the expression of cyclooxygenase-2 (COX-2) mRNA in a dose-dependent manner. In spite of immune suppression by MTX, COX-2 mRNA was induced by co-treatment with APA-01. These results suggest that APA-01 stimulates the proliferation of spleen cells, regulates the expression of COX-2 mRNA, and accelerates the recovery of inhibition of spleen cell proliferation induced by MTX, thus providing the immunological basis for clinical benefit of APA-01.