• 한국산업보건학회지
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• 제17권3호
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• pp.235-244
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• 2007

By comparing the proteins from the workers exposed to styrene with the ones from controls, it may be possible to identify proteins that play a role in the occurrence and progress of occupational disease and thus to study the molecular mechanisms of occupational disease. In order to find the biomarkers for assessing the styrene effects early, before clinical symptoms develop and to understand the mechanisms of adverse health effects, we surveyed 134 employees, among whom 52 workers(30 male and 22 female) were chronically exposed to styrene in 10 glass-reinforced plastic boat manufacturing factories in Korea and 82 controls had never been occupationally exposed to hazardous chemicals including styrene. The age and drinking habits and serum biochemistry such as total protein, BUN and serum creatinine in both groups were significantly different. Exposed workers were divided into three groups according to exposure levels of styrene(G1, below 1/2 TLV; G2, 1/2 TLV to TLV; G3, above TLV). The mean concentration of airborne styrene in G1 group was $10.93{\pm}11.33ppm$, and those of urinary mandelic acid(MA) and phenylglyoxylic acid(PGA) were $0.17{\pm}0.21$ and $0.13{\pm}0.11g/g$ creatinine, respectively. The mean concentration of airborne styrene in G2 and G3 groups were $47.54{\pm}22.43$ and $65.33{\pm}33.47ppm$, respectively, and levels of urinary metabolites such as MA and PGA increased considerably as expected with the increase in exposure level of styrene. The airborne styrene concentration were significantly correlated to the urinary concentration of MA(r=0.784, p=0.000) and PGA(r=0.626, p<0.001). In the 2D electrophoresis, the concentration of five proteins including complement C3 precursor, alpha-1-antitrypsin(AAT), vitamin D binding protein precursor(DBP), alpha-1-B-glycoprotein(A1BG) and inter alpha trypsin inhibitor(ITI) heavy chain-related protein were significantly altered in workers exposed to styrene compared with controls. While expression of complement C3 precursor and AAT increased by exposure to styrene, expression of DBP, A1BG and ITI heavy chain-related protein decreased. These results suggest that the exposure of styrene might affects levels of plasma proteinase, carriers of endogenous substances and immune system. In particular, increasing of AAT with the increase in exposure level of styrene can explain the tissue damage and inflammation by the imbalance of proteinase/antiproteinase and decrease of DBP, A1BG and ITI heavy chain-related protein in workers exposed to styrene is associated with dysfunction and/or declination in immune system and signal transduction

• 한국산학기술학회논문지
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• 제21권10호
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• pp.159-165
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• 2020

식품에 대한 안전성 요구는 사회가 선진화되고 식품산업의 발달과 함께 식생활 양식 변화와 소비자의 인식변화로 인해 사회적 문제로 크게 대두되었다. 소비자들은 자신이 소비하는 식품에 대하여 더 많은 정보를 요구하고 있으며, 유통체계에서 발생하는 식품 스캔들에 민감하게 반응한다. 이와 같은 식품안전에 대한 관심 속에 블록체인 기술은 식품사기나 유통 중의 잘못된 식품 관리에 효과적으로 대응하는 수단으로서 주목을 받고 있다. 이는 식품의 공급망에서 이력추적의 정확성과 믿음을 담보함으로써 거래자 간 신뢰를 구축하고 안전한 식품 유통을 보장할 수 있기 때문이다. 본 연구에서는 농식품의 이력, 유통, 안전, 품질과 신선도 등 농식품이 갖고 있는 각종 정보를 공급자와 소비자 및 유통관계자에게 제공하고 관리할 수 있는 차세대 농식품 유통시스템을 제안한다. 생산, 가공, 유통, 판매, 소비 전 과정에서의 제품 상태 및 유통 상황 정보를 언제 어디서나 실시간으로 모니터링하고 제어할 수 있으며, 사용자는 사용자가 앱(App)을 통하여 각 식품의 안전 수준을 실시간으로 확인할 수 있다.

• International Journal of Internet, Broadcasting and Communication
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• 제13권4호
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• pp.103-111
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• 2021

In modern society, digital lifestyles are spreading to minimize contact with people and to receive contactless information. The spread trend has established an unmanned distribution system in which transactions through contactless technologies such as kiosks and chatbots are activated in face-to-face transactions with sellers and consumers. In order to streamline logistics supply worldwide, digital new deal based joint logistics hubs, unmanned courier storage platforms, and fresh logistics based last mile services have been developed into unmanned logistics systems, focusing on the intelligent logistics system automation process. Unmanned courier storage system installed in urban areas and home to daily logistics where volume is concentrated are provided with fresh logistics services through cold chain and receiving freights in contactless environments. Development is also underway to minimize safety accidents caused by courier services, such as managing various information based on the integrated control system. This paper defines the concept of integrated operation for the development of a platform for contactless unmanned courier storage device developed into next-generation logistics system. In addition, we intend to develop systems engineering-based output for deriving safety requirements and specifications by identifying risk sources that may occur in the operational scenario. Therefore, the goal is to establish a foundation for safety and reliability between interfaces of logistics systems to be installed in apartment and subway station environments that want to provide unmanned logistics services to various consumers.

• 한국콘텐츠학회논문지
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• 제15권8호
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• pp.46-52
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• 2015

공연장의 거대한 무대 세트나 장치에 움직임이 부여되면, 다양한 극적 효과를 연출할 수 있다. 본 논문에서 제안하는 프로그래밍 가능한 다축 체인 호이스트 서버 시스템은 이러한 연출의 자동화를 가능하게 한다. 본 시스템에는 PTP 기반의 임의 궤적 생성 방법, 다축 실시간 통신 제어 방법, 그리고 4 단계의 순차적인 안전 진단 알고리즘이 적용 되었으며, 호이스트들은 콘솔의 동기 제어에 의하여 시나리오의 연출 순서에 따라 자동적으로 움직인다. 12대 체인호이스트로 구성된 멀티 체인 호이스트 서버 시스템에 대한 1 ton 부하 및 대칭-비대칭 배치 부하에 대한 실험을 통해서 우수성을 검증하였다. 아울러 K-POP 공연에서 극적효과를 연출하는데 성공적으로 적용되었다.

• Nuclear Engineering and Technology
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• 제34권3호
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• pp.218-231
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• 2002

Using a three-dimensional numerical code, B3R developed for nuclide transport of an arbitrary length of decay chain in the buffer between the canister and adjacent rock in a high- level radioactive waste repository by adopting a finite difference method utilizing the control- volume scheme, some illustrative calculations have been done. A linear sorption isotherm, nuclide transport due to diffusion in the buffer and the rock matrix, and advection and dispersion along thin rigid parallel fractures existing in a saturated porous rock matrix as well as diffusion through the fracture wall into the matrix is assumed. In such kind of repository, buffer and rock matrix are known to be important physico-chemical harriers in nuclide retardation. To show effects of buffer and rock matrix on nuclide transport in HLW repository and also to demonstrate usefulness of B3R, several cases of breakthrough curves as well as three- dimensional plots of concentration isopleths associated with these two barriers are introduced for a typical case of decay chain of $^{234}$ Ulongrightarrow$^{230}$ Thlongrightarrow$^{226}$ Ra, which is the most important chain as far as the human environment is concerned.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2010년도 추계학술대회
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• pp.357-364
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• 2010

동아시아의 경제발전을 위한 공급망 경제의 발전모델을 수립하는데 연구의 목적이 있다. 한국, 일본, 중국, 러시아 그리고 북한을 포함한 동아시아 경제발전의 현황을 파악하고 주요 문제점을 중심으로 하여 해결방안을 제시하고, 수년 내에 도래할 새로운 동아시아의 새로운 공급망 경제의 통합시대를 준비하고자 한다. 무게중심점기법으로 동아시아의 무게중심점을 찾고 시나리오 기법으로 공급망 경제의 발전전략과 방안을 연구하고자 한다.

• 대한안전경영과학회지
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• 제8권6호
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• pp.149-157
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• 2006

This paper suggests the design and operation of value stream mapping(VSM) applied to project management, such as R&D, IT Investment. First this study represents design methodology of VSM process using SIPOC(Supplier, Input, Process, Output, Costumer). Second, this paper considers the identification and improvement plan about non-added value time for VSM using FPC(Flow Process Chart) and PERT/CPM. Last, this paper proposes VSM scheduling method using PERT/CPM and CCPM(Critical Chain Project Management)

• 한국안전학회지
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• 제9권1호
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• pp.140-145
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• 1994

Contributions of global warming potentials on CFC(Chlorofluorocarbon) and Ozone were calculated by Stefan-Boltzmann's law and environmental effects of its were discussed. As the greenhouse effect on the unit volume of CFC is the most strong in the infrared gases and the destruction of Ozone in stratosphere is also depends on CFC, therefore release of CFC should be prohibited. But the effect of restriction on CFC will be appeared more than 10 years later. Eventhough the Ozone layer is related to global warming, It should be protected because of maitaining food chain mode of life, preventing human disease, for example, cataract, dermatics etc.

• 대한안전경영과학회지
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• 제10권3호
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• pp.217-225
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• 2008

The inventory routing problem (IRP) is an important area of Supply Chain Management. The objective function of IRP is the sum of transportation cost and inventory cost. We propose an Artificial Immune System(AIS) to solve the IRP. AIS is one of natural computing algorithm. An hyper mutation and an vaccine operator are introduced in our research. Computation results show that the hyper mutation is useful to improve the solution quality and the vaccine is useful to reduce the calculation time.

• 한국안전학회지
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• 제13권1호
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• pp.64-69
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• 1998

Three kinds of N-fluoroacyl carboxy pyridinium chlorides were synthesized by the reaction of pyridine-carboxylic acid such as pyridine-2-carboxylic, pyridine-3-carboxylic and pyridine-4-carboxylic acid with long chain perfluoroacyl chloride. The surface chemical properties including surface tension, foaming power, foam stability, effectiveness of wettability and solubilizing effect were measured. These compounds showed good surface activities as emulsifying agent, solubilizing agent and fire-fighting agent.