• Maxillofacial Plastic and Reconstructive Surgery
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• v.33 no.4
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• pp.308-313
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• 2011

Purpose: Beta-tricalcium phosphate (${\beta}$-TCP) is a synthetic calcium phosphate ceramic that has widely been used as a bone material to repair bone defects. Despite many clinical studies, the molecular mechanism whereby this biomaterial alters the gene expression in osteoblasts to promote bone formation is poorly understood. Thus, we attempted to address this question by using microarray techniques to identify the genes that are differentially regulated in osteoblasts exposed to ${\beta}$-TCP. Methods: By using DNA microarrays, we identified several genes whose expression levels were significantly up- or down-regulated in osteoblast-likeMG-63cells cultured with ${\beta}$-TCP at a concentration of 100 mg/10 ml for 24 hours. Results: The differentially expressed genes covered a broad range of functional activities: signal transduction, transcription, cell cycle regulation, vesicular transport, apoptosis, immunity, cytoskeletal elements and cell proliferation and differentiation. Conclusion: The gene expression changes related to cell proliferation and differentiation, vesicle transport, immunity and defense could affect the osteogenic activities of osteoblasts for bone regeneration. However, further studies will be required to verify the relative importance of these genes in bone formation, their temporal and spatial expression patterns and their interactions with each other.

• Conservation Science in Museum
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• v.14
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• pp.29-35
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• 2013

In cases, such as white porcelain with openwork lotus scroll design, where the ceramics has intricate form and decorations, we normally use casts to restore the work, in that current restoration materials have short molding time which causes difficulties in delicate work. However, since using a cast for restoration requires longer work-time and uses more materials, we decided to restore in direct. Since the molding time in the restoration material is closely related to the workability, restoration material which secures longer work hours is necessary when directly restoring a complex form of body. Therefore we experimented on the work-time, color variation and workability as time passes by making mixtures of Epoxy putty and Baked clay in different ratios. As a result of the experiment, the mixture ratio of OS8:RQ2 turned out to be the most effective ratio.

• Geomechanics and Engineering
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• v.35 no.5
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• pp.511-523
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• 2023

Canal-side roads frequently collapse due to an unexpectedly greater soft-clay thickness with a rapid drawdown situation. This causes annually increased repair and reconstruction costs. This paper aims to explore the effect of soft-clay thickness on the failure in the canal-side road in the case study of Phra Nakhon Si Ayutthaya rural road no. 1043 (AY. 1043). Before the actual construction, a field vane shear test was performed to determine the undrained shear strength and identify the thickness of the soft clay at the AY. 1043 area. After establishing the usability of AY. 1043, the resistivity survey method was used to evaluate the thickness of the soft clay layer at the failure zone. The screw driving sounding test was used to evaluate the undrained shear strength for the road structure with a medium-stiff clay layer at the failure zone for applying to the numerical model. This model was simulated to confirm the effect of soft-clay thickness on the failure of the canal-side road. The monitoring and testing results showed the tendency of rapid drawdown failure when the canal-side road was located on > 9 m thick of soft clay with a sensitivity > 4.5. The result indicates that the combination of resistivity survey and field vane shear test can be successfully used to inspect the soft-clay thickness and sensitivity before construction. The preliminary design for preventing failure or improving the stability of the canal-side road should be considered before construction under the critical thickness and sensitivity values of the soft clay.

• Korean Journal of Construction Engineering and Management
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• v.11 no.6
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• pp.111-121
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• 2010

As the customer's interest for sidewalk block in the street or apartment complex is increasing, the materials of block which had been a concrete block exclusively are varied to clay paver, native rock and wood etc. Especially, the sales volume of clay paver which is environment-friendly and ergonomic is dramatically increasing every year with two digits growth rate, however, many problems like "Edge Cracking" "Freezing Breakage" "Bending Breakage" "Joint Gap" are happening frequently within a couple of hours after installation due to the durabilities. Because of the characteristics of Ceramic products, clay pavers are very easy to be broken when they are bumped against each other. In addition, they are relatively fragile by a freezing expansion breakage when exposed to water due to hydrophilic property as well as the intensity and absorptance of the products are varied with small difference from the production process such as production equipment and process control. Therefore, it costs a lot of money to repair the breakdown unless production and installation is carried out according to the strict criteria of the quality control. In this study, the symptoms of breakdown frequently happened in clay paver are classified by each type and finally the solution for this problem in the production of brick, installation and criteria of quality control through compressive strength and absorptance test is suggested.