• Title/Summary/Keyword: Center Loss

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Clinical Research of Atopic Dermatitis Treated by Hwangryeonhaedok-Tang in Cosmetics (아토피 피부염 환자에서 황연해독탕(黃連解毒湯)이 함유된 한방화장품에 대한 임상 연구)

  • Yun, Dae-Chul;Kim, Hee-Taek;Kim, Ee-Hwa;Ho, Dong-Su
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.6
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    • pp.1611-1620
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    • 2008
  • This clinical research was conducted to test patients with Atopic Dermatitis by external application with Hwangryeonhaedok-Tang in cosmetics. We gave scores to 31 patients who visited the Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology of Semyung University Jecheon Oriental Medical Hospital from May 15th, 2008 to June 26th. Fifteen patients were treated with the ointment that contain Hwangryeonhaedok-Tang (experimental group) and sixteen patients were treated with normal ointment that doesn't have Hwangryeonhaedok-Tang (control group) for 4 weeks. We observed change of total IgE, eosinophil count, Skin Temperature, Transepidermal Water Loss(TEWL), Skin Hydration and Skin pH. Also Clinical Index of Atopic Dermatitis(SCORAD Index) and global assesment of efficacy were used to evaluate the effects of Hwangryeonhaedok-Tang. Statistical analysis was performed by using frequency analysis and descriptive analysis. Statistical significance was achieved if the probability was less than 5%(p<0.05). After 4 weeks of external application treatment, SCORAD Index in experimental group was significant statistically decreased compared with control group. After 4 weeks of external application treatment, total IgE of both groups were decreased and eosinophil count in control group was decreased but experimental group was unstatistically decreased. Unstatistically, both groups didn't showed significant effect on Skin Temperature. Transepidermal Water Loss(TEWL) in both groups were increased but experimental group was significant decreased compared with control group. Skin Hydration in experimental group was significant statistically increased compared with control group. Statistically, both groups didn't showed significant effect on Skin pH. Only experimental group showed little increase. After 4 weeks of external application treatment, experimental group showed significant effect on global assesment of efficacy. Considering the above results, we can speculate that cosmetics with Hwangryeonhaedok-Tang has some therapeutical effects in mitigating the symptoms of Atopic Dermatitis.

An Analysis in Optimum Coupling Method of Cylindrical Dielectric Resonator Filter Designed by Non-decaying Mode Analysis (Non-decaying 모드 해석을 이용해서 설계한 원통형 유전체 공진기 여파기의 최적 결합 방법에 대한 분석)

  • Lee, Won-Hui;Park, Chang-Won;Kim, Tai-Shin;Hur, Jung;Lee, Sang-Young
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.38 no.7
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    • pp.14-21
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    • 2001
  • In this paper, we designed and fabricated C-band bandpass filter using dielectric resonators. From waveguide cutoff frequency which applied the region between adjacent dielectric resonators, the height of cavity is determined. The cavity's diameter is determined to the twice of dielectric resonator? diameter considering the conductor loss. The resonant frequency of the DR cavity is calculated with non decaying mode analysis. Conventionally, cylindrical dielectric resonator is analysed by Cohn's model which use the decaying mode in the region between dielectric resonator wall and circular cavity wall, which is an approximated method. The external quality factor, $Q_{ex}$ has found with simulation result using Ansoft's Maxwell simulation tool. The designed filter using dielectric resonators with dielectric constant of 45 has the passband center at 5.065GHz. The bandpass filter using dielectric resonators has about 1dB insertion loss, 20MHz bandwidth and more than 30dB attenuation at $f_0+15MHz$.

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THE THREE DIMENSIONAL FINITE ELEMENT ANALYSIS OF THE STRESS DISTRIBUTION ACCORDING TO THE THREAD DESIGNS AND THE MARGINAL BONE LOSS OF THE IMPLANTS (임프란트 나사형태와 치조골 흡수에 따른 응력분산의 3차원 유한요소법적 분석)

  • Kim, Il-Kyu;Son, Choong-Yul;Jang, Keum-Soo;Cho, Hyun-Young;Baek, Min-Kyu;Park, Sheung-Hoon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.1
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    • pp.60-71
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    • 2008
  • The objective of this study is to evaluate the stress distribution according to the thread design and the marginal bone loss of a single unit dental implant under the axial and offset-axial loading by three dimensional finite element analysis. The implants used had the diameter of 5mm and 4mm with 13mm in length and prosthesis with a conical type which is 6mm in height and 12mm in diameter. The thread designs were triangular, square and buttress. In the three dimensional finite element model with $15\times15\times20mm$ hexahedron and 2mm cortical thickness, implants were placed with crown to root ratio 7:12, 10:9, 13:6 and 16:3. And additionally the axial force of 100N were applied into 0mm, 2mm and 4mm away from the center of the implants. The results were as follows 1. The maximum von-Mises stress in cortical bone was concentrated to cervical area of implant, and in cancellous bone, apical portion. 2. Comparing the von-Mises stresses in cortical bone of 2mm and 4mm offset loading with central axial loading, it were increased to 3 and 5 times in diameter 4mm implant, and 2 and 4 times, in diameter 5mm implant. 3. The square threads were more effective than the triangular and butress as the longer diameter, the offset loading, and the worse crown to root ratio. 4. The von-Mises stresses were relatively stable until crown to root ratio 13:6, but it was suddenly increased at 16:3. From the results of this study, minimum requirement of crown to root ratio of implant is 2:1, and in the respect of crown to root ratio, diameter and offset loading, square threads are more effective than triangular and buttress threads.

Combustive Properties of Medium Density Fibreboard (MDF) Specimens Treated with Alkylenediaminoalkyl-Bis-Phosphonic Acid Derivatives (알킬렌디아미노알킬-비스-포스폰산 유도체에 의해 처리된 중밀도섬유판의 연소성)

  • Jin, Eui;Chung, Yeong-Jin
    • Fire Science and Engineering
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    • v.28 no.4
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    • pp.57-63
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    • 2014
  • This study was performed to test the combustive properties of Medium Density Fibreboard (MDF) specimens treated with piperazinomethyl-bis-phosphonic acid (PIPEABP), methylpiperazinomethyl-bis-phosphonic acid (MPIPEABP), and N,N-dimethylethylenediaminomethyl-bis-phosphonic acid (MDEDAP). MDF Plates were painted in three times with 15 wt% solution of the alkylenediaminoalkyl-bis-phosphonic acids at the room temperature, respectively. After drying specimen treated with chemicals, combustive properties were examined by the cone calorimeter (ISO 5660-1). It was indicated that the specimens treated with chemicals showed the later time to peak mass loss rate ($TMLR_{peak}$) = (340475) s than that of virgin plate by reducing the burning rate. In adition, the specimens treated with chemicals showed the higher $CO_{mean}$ production (0.0883~0.0963) kg/kg than that of virgin plate. Especially, the specimens treated with chemicals showed the higher mean smoke extinction area ($SEA_{mean}$) ($5m^2/kg{\sim}21.5m^2/kg$) than that of virgin plate. Thus, It is supposed that the combustion-retardation properties were improved by the partial due to the treated alkylenediaminoalkyl-bis-phosphonic acids in the virgin MDF Plate. However, It gave a negative effect on smoke reduction.

Fiber-optic Goniometer to Measure Knee Joint Angle for the Diagnosis of Gait Disturbance (보행장애 진단을 위한 무릎관절 각도 측정용 광섬유 각도센서)

  • Kim, S.G.;Shin, S.H.;Jeon, D.;Hong, S.H.;Sim, H.I.;Jang, K.W.;Yoo, W.J.;Lee, B.
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.7
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    • pp.1009-1013
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    • 2013
  • In this study, we developed a fiber-optic goniometer for the continuous measurement of knee joint angle which provides important medical information on Alzheimer's disease. The fiber-optic goniometer is composed of a light-emitting diode (LED), a plastic optical fiber (POF), and a voltage output photodiode (PD). As a sensing part of the fiber-optic goniometer, a unclad fiber with regular intervals of 1 mm was fabricated to improve efficiency of bending loss according to the angle variation of knee joint. The emitting light with a center wavelength of 470 nm from a LED is guided by a POF to the PD, the transmitted light is then attenuated by the bending loss inside the bent POF. The intensity variation of the light transmitted from the POF gives rise to a change in output voltage in the fiber-optic goniometer. Therefore, we measured the real-time output voltage of the proposed fiber-optic goniometer using the unclad fiber according to the knee joint angle. Through the repeated experiments, the fiber-optic goniometer shows that it has a reversibility and a wide measurable angle range.

A Genome-Wide Study of Moyamoya-Type Cerebrovascular Disease in the Korean Population

  • Joo, Sung-Pil;Kim, Tae-Sun;Lee, Il-Kwon;Kim, Joon-Tae;Park, Man-Seok;Cho, Ki-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.50 no.6
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    • pp.486-491
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    • 2011
  • Objective : Structural genetic variation, including copy-number variation (CNV), constitutes a substantial fraction of total genetic variability, and the importance of structural variants in modulating susceptibility is increasingly being recognized. CNV can change biological function and contribute to pathophysiological conditions of human disease. Its relationship with common, complex human disease in particular is not fully understood. Here, we searched the human genome to identify copy number variants that predispose to moya-moya type cerebrovascular disease. Methods : We retrospectively analyzed patients who had unilateral or bilateral steno-occlusive lesions at the cerebral artery from March, 2007, to September, 2009. For the 20 subjects, including patients with moyamoya type pathologies and three normal healthy controls, we divided the subjects into 4 groups : typical moyamoya (n=6), unilateral moyamoya (n=9), progression unilateral to typical moyamoya (n=2) and non-moyamoya (n=3). Fragmented DNA was hybridized on Human610Quad v1.0 DNA analysis BeadChips (Illumina). Data analysis was performed with GenomeStudio v2009.1, Genotyping 1.1.9, cnvPartition_v2.3.4 software. Overall call rates were more than 99.8%. Results : In total, 1258 CNVs were identified across the whole genome. The average number of CNV was 45.55 per subject (CNV region was 45.4). The gain/loss of CNV was 52/249, having 4.7 fold higher frequencies in loss calls. The total CNV size was 904,657,868, and average size was 993,038. The largest portion of CNVs (613 calls) were 1M-10M in length. Interestingly, significant association between unilateral moyamoya disease (MMD) and progression of unilateral to typical moyamoya was observed. Conclusion : Significant association between unilateral MMD and progression of unilateral to typical moyamoya was observed. The finding was confirmed again with clustering analysis. These data demonstrate that certain CNV associate with moyamoya-type cerebrovascular disease.

The Prevalence Subjective Symptom of Cumulative Trauma Disorders and Related Risk Factors among Workers in Automobile Assembly Plant (자동차 조립공장 근로자의 누적외상성질환 자각증상 호소율과 관련 위험요인)

  • Kim, Chang-Sun;Kim, Kwang-Jong;Choi, Jae-wook;Yoon, Soo-Jong
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.11 no.1
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    • pp.85-91
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    • 2001
  • Background : It goes without saying that cumulative trauma disorders is spreading to various types of occupation in many advanced countries including America, and it forms considerable rate of total occupational disorders already. and as the result of it, the seriousness of worker health problem and economic loss owing to production loss, recuperation expense, etc. are on the increasing trend through whole society. In case of Korea, the related measures as well as accurate fact-finding survey data on cumulative trauma disorders aren't prepared in detail, so it implies forward problem would be serious. Purpose : The purpose of this study is to draw the risk factor of cumulative trauma disorders in production factory, to forecast the rate of occurrence of cumulative trauma disorders on the basis of subjective symptoms, and to present forward realistic and effective prevention measures by showing the risk of cumulative trauma disorders, objecting the production factory of a domestic riding automobile assembly shop, by estimating in the aspect of human-engineering through the analysis of risk factor being a cause of cumulative trauma disorders. Methods : For this study, I investigated work type and on-duty hours, breathing time, and subjective symptoms of cumulative trauma disorders through questionnaire, objecting the workers in press. car body, coating, and outfit factory. Results : As a result of research, 81.2% of workers were in the physical burden due to present working, and the highest prevalence by part of body is an waist. The higher a rule score, The higher the number of workers complaind for working intensity, and the higher age work duration, tool used time, the higher prevalence of subjective symptoms by part of body. The number of workers complaind subjective symptom for treatment is the highest in drugstore.

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Grid Cell Analysis using Species Diversity Index of Birds in the Northern Area of Yeongjong Island, Incheon, Korea (영종도 북부지역의 조류 종다양도를 이용한 격자별 공간 분석)

  • Kang, Jong-Hyun;Cho, Hang-Soo;Lee, Yun-Kyoung;Kim, Dong-Won;Kim, Chang-Hoe;Kim, Myungjin;Bae, Yang-Seop
    • Journal of Environmental Impact Assessment
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    • v.21 no.5
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    • pp.649-664
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    • 2012
  • The grid cell analysis is used to select good sites as habitats at the region. The northern area of Yeongjong Island, Incheon has been disturbing by habitat loss due to human activities such as residential development, deforestation. In order to determine significant places as bird habitats and to select conservation areas at this island, the study area was divided into 70 grid cells($500{\times}500m$ each grid) and then each grid was ranked by spatial analysis using the species diversity index. Fieldwork was carried out in Spring and Autumn of 2010. To examine grid cells which were ranked high in both seasons in common, we used the average ranking value, combined data from two seasons. This area consists of mainly agricultural areas and forests(more than 68%) among eight habitat types: the agricultural land, forest, coast, lake, meadow, stream, city and other things. A total of 110 species was recorded: 4,183 birds of 102 species in Spring and 3,326 birds of 58 species in Autumn. In other words, the number of individuals and species was higher in Spring than in Autumn. Species diversity index presented the highest value at M8 grid cell in Spring(3.380) and at A4 gird cell in Autumn(2.736). In 18 of 22 grid cells where the average ranking value was higher than 3, the forest was distributed and in 4 grid cells, the coast and wetland were widely distributed, in which theses were located apart from human-associated disturbances such as construction works for a leisure complex. Our results present a new estimate method not only to minimize loss of bird habitats but also to conserve important habitats when the large-scale development takes place at particular region.

Corona Discharge Characteristics and Particle Losses in a Unipolar Corona-needle Charger Obtained through Numerical and Experimental Studies

  • Intra, Panich;Yawootti, Artit;Rattanadecho, Phadungsak
    • Journal of Electrical Engineering and Technology
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    • v.12 no.5
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    • pp.2021-2030
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    • 2017
  • In this paper, the unipolar corona-needle charger was developed and its capabilities were both numerically and experimentally investigated. The experimental corona discharges and particle losses in the charger were obtained at different corona voltage, aerosol flow rate and particle diameter for positive and negative coronas. Inside the charger, the electric field and charge distribution and the transport behavior of the charged particle were predicted by a numerical simulation. The experimental results yielded the highest ion number concentrations of about $1.087{\times}10^{15}ions/m^3$ for a positive corona voltage of about 3.2 kV, and $1.247{\times}10^{16}ions/m^3$ for a negative corona voltage of about 2.9 kV, and the highest $N_it$ product for positive and negative coronas was found to about $7.53{\times}10^{13}$ and $8.65{\times}10^{14}ions/m^3$ s was occurred at the positive and negative corona voltages of about 3.2 and 2.9 kV, respectively, and the flow rate of 0.3 L/min. The highest diffusion loss was found to occur at particles with diameter of 30 nm to be about 62.50 and 19.33 % for the aerosol flow rate of 0.3 and 1.5 L/min, respectively, and the highest electrostatic loss was found to occur at particles with diameters of 75 and 50 nm to be about 86.29 and 72.92 % for positive and negative corona voltages of about 2.9 and 2.5 kV, respectively. The numerical results for the electric field distribution and the charged particles migration inside the charger were used to guide the description of the electric field and the behavior of charged particle trajectories to improve the design and refinement of a unipolar corona-needle charger that otherwise could not be seen from the experimental data.

Lightweight Authentication Scheme for Secure Data Transmission in Terrestrial CNPC Links (지상 CNPC 링크에서 안전한 데이터 전송을 위한 경량화된 인증기법)

  • Kim, Man Sik;Jun, Moon-Seog;Kang, Jung Ho
    • KIPS Transactions on Software and Data Engineering
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    • v.6 no.9
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    • pp.429-436
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    • 2017
  • Unmanned Aerial Vehicles (UAV) that are piloted without human pilots can be commanded remotely via frequencies or perform pre-inputted missions. UAVs have been mainly used for military purposes, but due to the development of ICT technology, they are now widely used in the private sector. Teal Group's 2014 World UAV Forecast predicts that the UAV market will grow by 10% annually over the next decade, reaching $ 12.5 billion by 2023. However, because UAVs are primarily remotely controlled, if a malicious user accesses a remotely controlled UAV, it could seriously infringe privacy and cause financial loss or even loss of life. To solve this problem, a secure channel must be established through mutual authentication between the UAV and the control center. However, existing security techniques require a lot of computing resources and power, and because communication distances, infrastructure, and data flow are different from UAV networks, it is unsuitable for application in UAV environments. To resolve this problem, the study presents a lightweight UAV authentication method based on Physical Unclonable Functions (PUFs) that requires less computing resources in the ground Control and Non-Payload Communication (CNPC) environment, where recently, technology standardization is actively under progress.