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Development of Primary Standard Gas Mixtures for Monitoring Monoterpenes (α-pinene, 3-carene, R-(+)-limonene, 1,8-cineole) Ambient Levels (at 2 nmol/mol) (대기 중 모노테르펜 (α-피넨, 3-카렌, R-리모넨, 1,8-시네올) 측정을 위한 혼합표준가스개발)

  • Kang, Ji Hwan;Kim, Mi Eon;Kim, Young Doo;Rhee, Young Woo;Lee, Sangil
    • Journal of Korean Society for Atmospheric Environment
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    • v.32 no.3
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    • pp.320-328
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    • 2016
  • Among biogenic volatile organic compounds (BVOCs) in the natural ecosystem, monoterpenes, along with isoprene, play important roles in atmospheric chemistry and make significant impacts on air pollution and climate change, especially due to their contribution to secondary organic aerosol production and photochemical ozone formation. It is essential to measure monoterpene concentrations accurately for understanding their oxidation processes, emission processes and estimation, and interactions between biosphere and atmosphere. Thus, traceable calibration standards are crucial for the accurate measurement of monoterpenes at ambient levels. However, there are limited information about developing calibrations standards for monoterpenes in pressured cylinders. This study describes about developing primary standard gas mixtures (PSMs) for monoterpenes at about 2 nmol/mol, near ambient levels. The micro-gravimetric method was applied to prepare monoterpene (${\alpha}$-pinene, 3-carene, R-(+)-limonene, 1,8-cineole) PSMs at $10{\mu}mol/mol$ and then the PSMs were further diluted to 2 nmol/mol level. To select an optimal cylinder for the development of monoterpene PSMs, three different kinds of cylinders were used for the preparation and were evaluated for uncertainty sources including long-term stability. Results showed that aluminum cylinders with a special internal surface treatment (Experis) had little adsorption loss on the cylinder internal surface and good long-term stability compared to two other cylinder types with no treatment and a special treatment (Aculife). Results from uncertainty estimation suggested that monoterpene PSMs can be prepared in pressured cylinders with a special treatment (Experis) at 2 nmol/mol level with an uncertainty of less than 4%.

Assesment of the industrial Wood Waste Disposal Cost through Analysis of the Treatment Flow (사업장계 폐목재의 흐름 분석을 통한 처리비용영향 검토)

  • Kim, Jaenam;Kim, Sujin;Phae, Chaegun
    • Journal of the Korea Organic Resources Recycling Association
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    • v.20 no.3
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    • pp.34-40
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    • 2012
  • This research has looked into the treatment process of wood waste generated from industrial waste within the region and in order to modify the problem that may occurred during the mass balance were analyzed for development of suitable solid waste recycling network regionally. As as result, quite amount of wood waste are being transferred to another region, even though a treatment facility's capacity could bear the total amount of waste generated within the area. Although the wood waste could be treated locally, it is analyzed that amount of wood waste are being transferred due to inefficient and irrational processing system between regions. It is assumed that $CO_2$ generated and loss of unnecessary fuel cost from these inefficient system is quite a lot and in order to modify this disorganized system, it will not inevitable to treat the waste based on the characteristics of each regions. Also, the wood waste recycling system should be studied with the efficient, environmental friendly processing and delivering network by minimized transfer distance and local systemizing the waste treatment system.

Mixture of Extracts of Cynanchum wilfordii and Phlomis umbrosa Turcz. Does Not Have an Estrogenic Effect in Ovariectomized Rats (백수오와 한속단 추출물의 비에스트로젠 효과에 관한 연구)

  • Han, Song-Hee;Lee, Tae-Hee;Jang, Ja-Young;Song, Hyun-Kyung;Hong, Sang-Keun;Kim, Yu-Ri;Han, Beom-Seok
    • Korean Journal of Food Science and Technology
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    • v.47 no.5
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    • pp.667-672
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    • 2015
  • Cynanchum wilfordii and Phlomis umbrosa Turcz. are known to contain isoflavone, a representative phytoestrogen. This study was performed to determine whether the extract mixture of C. wilfordii and P. umbrosa Turcz. would induce an estrogenic effect in ovariectomized rats. The extracts were administered to the ovariectomized rats at 30, 60, 120 mg/kg per day for 4 weeks, respectively. They showed no estrogenic effect, which was indicated by the decrease in uterus wall thickness as well as the increase in body weight and the level of cholesterol and triglyceride. The extracts also had no effect on the concentrations of estrogen and growth hormone in the serum. However, the increase in alkaline phosphatase activity, which leads to protection against the bone loss caused by ovariectomy, was noted on administration of the extract. Therefore, it seemed that the extracts of C. wilfordii and P. umbrosa Turcz. had no estrogenic effect in rats.

Effects of Oral Intake of Gromwell Water Fraction on Ceramides Content and the Development of Atopic Dermatitis in NC/Nga Mice (자초 추출물 극성 성분의 피부 보습 증진 및 아토피 피부염 호전 효과)

  • Kim, Young-Ran;Cho, Si-Young;Seo, Dae-Bang;Kim, Sung-Han;Lee, Sang-Jun;Cho, Yun-Hi
    • Korean Journal of Food Science and Technology
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    • v.41 no.5
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    • pp.547-551
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    • 2009
  • Gromwell (LE, Lithospermum erythrorhizon), a perennial herbal plant, has been used for the treatment of various problems associated with atopic dermatitis of the skin, such as water loss, epidermal hyperproliferation, and severe inflammation. Previously, it was shown that oral supplementation with a 70% ethanol extract of gromwell prevented the development of atopic dermatitis in NC/Nga mice. In this study, in order to identify the fraction that mediates gromwell's efficacy, the dietary effects of water and ethyl acetate fractions from the ethanol extract of gromwell were assessed in the development of dermatitis using NC/Nga mice. Dietary supplementation of the hot water fraction significantly reduced scores for epidermal hyperproliferation in parallel with a marked increase of ceramides. Supplementation of the gromwell hot water fraction also decreased scratching behavior, which was accompanied by a decrease in plasma levels of IgE. These results showed that the hot water fraction of the gromwell ethanolic extract prevented the development of atopic dermatitis by increasing ceramides in NC/Nga mice.

Prediction and analysis of structural noise of a box girder using hybrid FE-SEA method

  • Luo, Wen-jun;Zhang, Zi-zheng;Wu, Bao-you;Xu, Chang-jie;Yang, Peng-qi
    • Structural Engineering and Mechanics
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    • v.75 no.4
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    • pp.507-518
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    • 2020
  • With the rapid development of rail transit, rail transit noise needs to be paid more and more attention. In order to accurately and effectively analyze the characteristics of low-frequency noise, a prediction model of vibration of box girder was established based on the hybrid FE-SEA method. When the train speed is 140 km/h, 200 km/h and 250 km/h, the vibration and noise of the box girder induced by the vertical wheel-rail interaction in the frequency range of 20-500 Hz are analyzed. Detailed analysis of the energy level, sound pressure contribution, modal analysis and vibration loss power of each slab at the operating speed of 140 km /h. The results show that: (1) When the train runs at a speed of 140km/h, the roof contributes more to the sound pressure at the far sound field point. Analyzing the frequency range from 20 to 500 Hz: The top plate plays a very important role in controlling sound pressure, contributing up to 70% of the sound pressure at peak frequencies. (2) When the train is traveling at various speeds, the maximum amplitude of structural vibration and noise generated by the viaduct occurs at 50 Hz. The vibration acceleration of the box beam at the far field point and near field point is mainly concentrated in the frequency range of 31.5-100 Hz, which is consistent with the dominant frequency band of wheel-rail force. Therefore, the main frequency of reducing the vibration and noise of the box beam is 31.5-100 Hz. (3) The vibration energy level and sound pressure level of the box bridge at different speeds are basically the same. The laws of vibration energy and sound pressure follow the rules below: web

Study on Digital Restoration by 3-dimensional Image for Gilt Bronze Cap Excavated from the Ancient Tomb of Andong, Goheung (고흥 안동고분 출토 금동관모의 3차원 디지털 복원연구)

  • Lee, Joo-Wan;Oh, Jung-Hyun;Kim, Sa-Dug
    • Journal of Conservation Science
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    • v.27 no.2
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    • pp.181-190
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    • 2011
  • A precision measurement and digital image restoration of the 5th century's gilt bronze cap of Baekje dynasty, excavated from the ancient tomb of Andong, Goheung in 2006, was undertaken. The objective of the scanning is to preserve precise feature of the artefact in the form of digital data by embodying it in 3 dimensional space. Acquirement of the data has been undertaken in the following process : 3D scanning to obtain 3D shape and color information(original data photographing)-3D modelling(joining original data and restoring non-photographed or damaged area)-CG image production. Production of restoration CG image was based on joined shape of original data and each part's measurement on CAD. Non-photographed part and area of loss was restored referring actual measurement and research result of excavated cap from the 5th to 8th century. 3D image restoration is one of artefact restoration methods which restores artefact without risk. It is also undertaken with historical research. As result, this method can enhance aesthetic and academic value of the artefact by successful restoration.

Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study

  • Lee, Dong Eun;Huh, Chul-Sung;Ra, Jehyeon;Choi, Il-Dong;Jeong, Ji-Woong;Kim, Sung-Hwan;Ryu, Ja Hyun;Seo, Young Kyoung;Koh, Jae Sook;Lee, Jung-Hee;Sim, Jae-Hun;Ahn, Young-Tae
    • Journal of Microbiology and Biotechnology
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    • v.25 no.12
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    • pp.2160-2168
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    • 2015
  • The beneficial effects of probiotics are now widely reported, although there are only a few studies on their anti-aging effects. We have found that Lactobacillus plantarum HY7714 (HY7714) improves skin hydration and has anti-photoaging effects, and in the present study, we have further evaluated the anti-aging effect of HY7714 via a randomized, double blind, placebo-controlled clinical trial. The trial included 110 volunteers aged 41 and 59 years who have dry skin and wrinkles. Participants took 1 × 1010 CFU/day of HY7714 (probiotic group) or a placebo (placebo group) for 12 weeks. Skin hydration, wrinkles, skin gloss, and skin elasticity were measured every 4 weeks during the study period. There were significant increases in the skin water content in the face (p < 0.01) and hands (p < 0.05) at week 12 in the probiotic group. Transepidermal water loss decreased significantly in both groups at weeks 4, 8, and 12 (p < 0.001 compared with baseline), and was suppressed to a greater extent in the face and forearm in the probiotic group at week 12. Volunteers in the probiotic group had a significant reduction in wrinkle depth at week 12, and skin gloss was also significantly improved by week 12. Finally, skin elasticity in the probiotic group improved by 13.17% (p < 0.05 vs. controls) after 4 weeks and by 21.73% (p < 0.01 vs. controls) after 12 weeks. These findings are preliminary confirmation of the anti-aging benefit to the skin of L. plantarum HY7714 as a nutricosmetic agent.

Effects of natural raw meal (NRM) on high-fat diet and dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6J mice

  • Shin, Sung-Ho;Song, Jia-Le;Park, Myoung-Gyu;Park, Mi-Hyun;Hwang, Sung-Joo;Park, Kun-Young
    • Nutrition Research and Practice
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    • v.9 no.6
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    • pp.619-627
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    • 2015
  • BACKGROUND/OBJECTIVES: Colitis is a serious health problem, and chronic obesity is associated with the progression of colitis. The aim of this study was to determine the effects of natural raw meal (NRM) on high-fat diet (HFD, 45%) and dextran sulfate sodium (DSS, 2% w/v)-induced colitis in C57BL/6J mice. MATERIALS/METHODS: Body weight, colon length, and colon weight-to-length ratio, were measured directly. Serum levels of obesity-related biomarkers, triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), insulin, leptin, and adiponectin were determined using commercial kits. Serum levels of pro-inflammatory cytokines including tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin (IL)-$1{\beta}$, and IL-6 were detected using a commercial ELISA kit. Histological study was performed using a hematoxylin and eosin (H&E) staining assay. Colonic mRNA expressions of TNF-${\alpha}$, IL-$1{\beta}$, IL-6, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) were determined by RT-PCR assay. RESULTS: Body weight and obesity-related biomarkers (TG, TC, LDL, HDL, insulin, leptin, and adiponectin) were regulated and obesity was prevented in NRM treated mice. NRM significantly suppressed colon shortening and reduced colon weight-to-length ratio in HFD+DSS induced colitis in C57BL/6J mice (P < 0.05). Histological observations suggested that NRM reduced edema, mucosal damage, and the loss of crypts induced by HFD and DSS. In addition, NRM decreased the serum levels of pro-inflammatory cytokines, TNF-${\alpha}$, IL-$1{\beta}$, and IL-6 and inhibited the mRNA expressions of these cytokines, and iNOS and COX-2 in colon mucosa (P < 0.05). CONCLUSION: The results suggest that NRM has an anti-inflammatory effect against HFD and DSS-induced colitis in mice, and that these effects are due to the amelioration of HFD and/or DSS-induced inflammatory reactions.

An Efficient Correction Process of CT-Simulator Couch with Current Diagnostic CT Scanners (진단용 CT-모의치료기 테이블의 효율적인 교정 방법)

  • Goo, Eun-Hoe;Lee, Jae-Seung;Cho, Jung-Keun;Moon, Seong-Kwon
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.254-261
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    • 2009
  • This study suggested that the table of CT-simulator and the laser alignment system using diagnostic CT scanner have an efficient method for improvement in alignment between the planned target center of traverse image with CT scanner. It was conducted on the daily QA when presented in the AAPM TG66 with correcting the laser alignment system using geometric trigonometric functions and investigated the effectiveness of correction methods as compared with those before and after correction. Before correction error was 3.82mm between the planned target center of image, the table longitudinal axis was twisted with 0.436o. The laser alignment system using geometric trigonometric functions in after correction was satisfied with tolerance limits of ${\pm}2mm$ when occurred about 0.7mm in errors between the planned target center. The table correction to satisfy the geometric accuracy is very inefficient over against the time and economic loss as well as technical limits in the case of application as only radiation therapy associated with CT-simulator with diagnostic CT scanner in use. But, the method which corrects the laser alignment system is economic and relatively simple with possibility of getting well geometric accuracy and we suppose that it is efficient method for applying in the clinic.

Cosmetical Properties of Polysccharides from the Root Bark of Ulmus davidiana var. Japonica (유근피로부터 추출한 다당류의 화장료적 특성)

  • Kim Young Sil;Kim Jong Heon;Kim Ki Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.4 s.48
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    • pp.509-514
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    • 2004
  • The fruit or root of Ulmus davidiana var. Japonica and its extract has traditionally been used as anti inflammatation medicines as well as a remedy of the digestive ulcer for a long time. Ulmus davidiana var. Japonica has also been used to cure palliative and diuresis, because it contains lot of mucus and tannin. In this study, we examined the moisturizing effect and anti-inflammation effect of polysaccharides extracted from Ulmus davidiana var. Japonica to investigated whether it can be used as a cosmetic ingredient or not. The polysaccharides were extracted from Ulmus davidiana var. Japonica. Then the hydrolyzed was obtained through the hydrolysis. It has been ascertained that the polysaccharides we mainly composed of rhamnose, galactose, and glucose through HPLC experiments, and it has 20,000 of the molecular weight and 89.3 dL/g of intrinsic viscosity In a moisturizing test of measuring water loss in a desiccator and moisture content by Comeometer CM820, Ulmus davidiana root extract showed a similar moisturizing effect as hyaluronic acid. And its anti-inflammation effect on carrageenin-induced edema evaluated by measuring the thickness of swelling over paw induced by carrageenin (25 uL of $2\%$ carrageenin saline injection), the $\%$ swelling over paw treated with Ulmus davidiana root extract was much less than that of paw treated with carrageenin only. The anti-inflammatory effect of Ulmus davidiana root extract was almost similar to that of ketoprofen. These results can say that Ulmus davidiana root extract can be effectively used as a cosmetic ingredient.