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A Study of Gamma-ray Irradiation Effects on Commercially Available Single-mode Optical Fiber (국내외 상용 단일모드 광섬유의 감마선 영향 분석 연구)

  • Kim, Jong-Yeol;Lee, Nam-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.05a
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    • pp.564-567
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    • 2012
  • Optical fibers are going to be used for telecommunication, image fibers, sensors under irradiation in nuclear power plants and various irradiation facilities. Especially, Temperature detection sensors using Raman light scattering, temperature or strain sensors using fiber gratings, magnet-optical sensors using photo-magnetic effect, are already commercialized. However, When fibers are exposed to ionizing radiation, color centers are formed in fibers which reduces their light transmission, and it is limited in applying under radiation environments. In this study, $Co^{60}$ gamma-ray induced optical attenuation on Ge-doped single mode(SM) fiber has been measured. Gamma-ray is irradiated for 4hours at the dose rate of 0.5kGy/hr, 2kGy/hr, 8kGy/hr. Consequently, gamma-ray induced loss based on radiation effects in Ge-doped SM fiber occur precisely. Furthermore, dose rate effect that the higher dose rate in the same total dose, the more increase loss of optical fiber and annealing effect that the higher the loss after irradiation, the more increase the recovery rate of the loss are observed in the fiber. This results plan to make use of bases in the study of the radiation-hardened optical fiber.

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Sex-related Differences in DNA Copy Number Alterations in Hepatitis B Virus-Associated Hepatocellular Carcinoma

  • Zhu, Zhong-Zheng;Wang, Dong;Cong, Wen-Ming;Jiang, Hongmei;Yu, Yue;Wen, Bing-Ji;Dong, Hui;Zhang, Xiao;Liu, Shu-Fang;Wang, Ai-Zhong;Zhu, Guanshan;Hou, Lifang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.225-229
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    • 2012
  • Background: Males have a higher prevalence of hepatocellular carcinoma (HCC) than females in general, but the reasons for the sex disparity are still obscure. DNA copy number alteration (CNA) is a major feature of solid tumors including HCC, but whether CNA plays a role in sex-related differences in HCC development has never been evaluated. Methods: High-resolution array comparative genomic hybridization (CGH) was used to examine 17 female and 46 male HCC patients with chronic hepatitis B virus (HBV) infection in Shanghai, China. Two-tailed Fisher's exact or ${\chi}^2$ tests was used to compare CNAs between females and males. Results: The overall frequencies and patterns of CNAs in female and male cases were similar. However, female HCC tumors presented more copy number gains compared to those in males on 1q21.3-q22 (76.5% vs. 37.0%, P = 0.009), 11q11 (35.3% vs. 0.0%, P = 0.0002) and 19q13.31-q13.32 (23.5% vs. 0.0%, P = 0.004), and loss on 16p11.2 (35.3% vs. 6.5%, P = 0.009). Relative to females, male cases had greater copy number loss on 11q11 (63.0% vs. 17.6%, P = 0.002). Further analyses showed that 11q11 gain correlated with 19q13.31-q13.32 gain (P = 0.042), 11q11 loss (P = 0.011) and 16p11.2 loss (P = 0.033), while 1q21.3-q22 gain correlated with 19q13.31-q13.32 gain (P = 0.046). Conclusions: These findings suggest that CNAs may play a role in sex-related differences in HBVassociated HCC development.

Retrospective long-term analysis of bone level changes after horizontal alveolar crest reconstruction with autologous bone grafts harvested from the posterior region of the mandible

  • Voss, Jan Oliver;Dieke, Tobias;Doll, Christian;Sachse, Claudia;Nelson, Katja;Raguse, Jan-Dirk;Nahles, Susanne
    • Journal of Periodontal and Implant Science
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    • v.46 no.2
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    • pp.72-83
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    • 2016
  • Purpose: The goal of this study was to evaluate the long-term success of horizontal alveolar crest augmentation of the retromolar region of the mandible with particulated bone, as well as factors affecting subsequent peri-implant bone loss. Methods: A total of 109 patients (68 female, 41 male) suffering from alveolar ridge deficiencies of the maxilla and mandible were included in this study. All patients were treated with particulated retromolar bone grafts from the mandible prior to the insertion of endosseous dental implants. Mesial and distal peri-implant crestal bone changes were assessed at six time points. Several parameters, including implant survival and the influence of age, gender, localisation of the implant, diameter, covering procedures, and time points of implant placement, were analysed to identify associations with bone level changes using the Mann-Whitney U-test, the Kruskal-Wallis test, and Spearman's rank-order correlation coefficient. Results: A total of 164 dental implants were placed in the maxilla (n=97) and in the mandible (n=67). The mean observation period was $105.26{\pm}21.58$ months after implantation. The overall survival rate was 97.6% after 10 years. Overall, peri-implant bone loss was highest during the first year, but decreased over time. The mean amount of bone loss after 10 years was 2.47 mm mesially and 2.50 mm distally. Bone loss was significantly influenced by implant type and primary stability. Conclusions: The use of particulated autologous retromolar bone grafts is a reliable technique for the horizontal reconstruction of local alveolar ridge deficiencies. Our results demonstrate that implants placed in augmented bone demonstrated similar bone level changes compared to implants inserted in non-augmented regions.

Effects of cooking method and final core-temperature on cooking loss, lipid oxidation, nucleotide-related compounds and aroma volatiles of Hanwoo brisket

  • Utama, Dicky Tri;Baek, Ki Ho;Jeong, Hae Seong;Yoon, Seok Ki;Joo, Seon-Tea;Lee, Sung Ki
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.2
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    • pp.293-300
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    • 2018
  • Objective: This study observed the effects of cooking method and final core temperature on cooking loss, lipid oxidation, aroma volatiles, nucleotide-related compounds and aroma volatiles of Hanwoo brisket (deep pectoralis). Methods: Deep pectoralis muscles (8.65% of crude fat) were obtained from three Hanwoo steer carcasses with $1^+$ quality grade. Samples were either oven-roasted at $180^{\circ}C$ (dry heat) or cooked in boiling water (moist heat) to final core temperature of $70^{\circ}C$ (medium) or $77^{\circ}C$ (well-done). Results: Boiling method reduced more fat but retained more moisture than did the oven roasting method (p<0.001), thus no significant differences were found on cooking loss. However, samples lost more weight as final core temperature increased (p<0.01). Further, total saturated fatty acid increased (p = 0.02) while total monounsaturated fatty acid decreased (p = 0.03) as final core temperature increased. Regardless the method used for cooking, malondialdehyde (p<0.01) and free iron contents (p<0.001) were observed higher in samples cooked to $77^{\circ}C$. Oven roasting retained more inosinic acid, inosine and hypoxanthine in samples than did the boiling method (p<0.001), of which the concentration decreased as final core temperature increased except for hypoxanthine. Samples cooked to $77^{\circ}C$ using oven roasting method released more intense aroma than did the others and the aroma pattern was discriminated based on the intensity. Most of aldehydes and pyrazines were more abundant in oven-roasted samples than in boiled samples. Among identified volatiles, hexanal had the highest area unit in both boiled and oven-roasted samples, of which the abundance increased as the final core temperature increased. Conclusion: The boiling method extracted inosinic acid and rendered fat from beef brisket, whereas oven roasting intensified aroma derived from aldehydes and pyrazines and prevented the extreme loss of inosinic acid.

Temperature Compensation of 8 Channel DWDM Multiplexer Using All Optical fiber Mach-Zehnder Structure (전광섬유형 8채널 DWDM용 광다중화기의 온도보상 특성)

  • Chang, Jin-Hyeon;Jung, Jin-Ho;Kim, Young-Kwon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.8A
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    • pp.697-704
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    • 2005
  • In this paper, Passive Temperature Compensation Technology is apply to 8-channel Optical multiplexer with 1000Hz channel spacing. The 8-channel multiplexer is fabricated by connecting three cascaded Mach Zehnder Interferometer(MZI) of optical fiber type, and each interferometer has the wavelength interval of 100GHz, 2000Hz and 4000Hz, respectively. Furthermore, to acquire uniform insertion loss, it is fabricated by using Wavelength Flatten Coupler(WFC) in which the variation of insertion loss is low. $CO_2$ laser to adjust precisely the wavelength. The optical fiber is very sensitive in the thermal variation around. Thus, When fabrication the prototype, it is applied a technique to compensate the optical thermal effect because the center wavelength at the output is shifted according to the thermal variation around. In summary, The prototype composed by eight cascaded MZI has an insertion loss of 5.5 dB, the bandwidth of 0.8nm at 0.5 dB point, and channel crosstalk of 25 dB. Furthermore, the loss dependent on polarization is measured as 0.06dB. Consequently, the output wavelength is shifted within 0.05 m when the surrounding temperature varies until $60^{\circ}C$

Evaluation of factors affecting sensory neural hearing loss (감각신경성 청력손실에 영향을 미치는 제 요인에 관한 연구)

  • Hong, Seong-Chul;Bae, Seong-Wook;Lee, Jong-Young
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.2 s.61
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    • pp.249-264
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    • 1998
  • Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. first, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.

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Characteristics study on fire-resistant paint used by TGA-IR (TGA-IR을 사용한 내화 도료의 특성에 관한 연구)

  • Cho, Nam-Wook;Shin, Hyun-Jun;Cho, Won-Bo;Lee, Seong-Hun;Rie, Dong-Ho;Kim, Hyo-Jin
    • Analytical Science and Technology
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    • v.24 no.3
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    • pp.168-172
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    • 2011
  • The iron frame of building could be collapsed or bent at $500^{\circ}C$. Therefore the fire-resistant paint should be applied for safety. This study performed the comparative analysis to show the characteristics of fireresistant paint. And then 12 products of fire resistant paint and 6 products of paints were used as samples. And the samples were analyzed by TGA (Thermogravimetric Analyzer) as analyzer for measuring the variation of weight on temper of weight by heating. When TGA analyzer could measure the variatiature, and FT-IR was measured for analyze gas components on variation on of weight by heating on 12 products of fire resistance, the samples showed to decrease 40% of weight to $800^{\circ}C$, and because paints had 50% to 40% of loss weight, it showed to be equal with loss weight of fire resistance paint on high temperature or was lower loss weight than it of fire resistance paints. However number 6 sample of fire resistance paints could show to decrease 20% of total weight on $800^{\circ}C$. And then in the case of FT-IR, fire resistance paints could show to have the high intensity of $CO_2$ spectrum as complete combustion. However paints could show to have the lower intensity of $CO_2$ spectrum, have the higher intensity of water spectrum. Therefore the TGA graph of result could be much different until $250^{\circ}C$. When it was burned, FT-IR spectrum could show to confirm the characteristics of fire resistance paints, and the characteristic could be confirmed on inorganic paint of fire resistance by weight loss of TGA.

Study on the Validity of Electromyography(EMG) And Early-performed Electroneurography(ENoG) as Predicting Factor for Facial Palsy - based on Collaborative Treatment between Korean and Western Medicine (안면신경마비 예후인자로서 근전도검사(EMG)와 조기 시행한 신경전도검사(ENoG)의 유용성에 대한 연구: 한양방 협진치료 기반으로)

  • Sung, Won Suk;Kim, Pil Kun;Goo, Bon Hyuk;Ryu, Hee Kyoung;Suk, Kyung Hwan;Lee, Ju Hyeon;Kim, Min Jeong;Park, Yeon Cheol;Seo, Byung Kwan;Park, Dong Suk;Baek, Yong Hyeon
    • Journal of Acupuncture Research
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    • v.30 no.4
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    • pp.115-123
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    • 2013
  • Objectives : This study was performed to confirm the usefulness of EMG and early-performed ENoG as predicting factor for facial palsy by clinical outcome. Methods : We gathered patients who visited the Facial Palsy Center in Kyung Hee University Hospital at Gangdong between January 2010 and September 2012. We used inclusion/exclusion criteria and reviewed 231 patients' medical records including gender, age, HB grade and EMG & ENoG axonal loss. We compared the relation between EMG axonal loss and improvement degree at 4 & 6 weeks after treatment, and between ENoG axonal loss at 3-5 & 6-8 days after onset and EMG axnoal loss using regression analysis. Results : Each analysis had statistical significance, but EMG & improvement degree at 6 weeks after treatment showed statistically higher correlation than that at 4 weeks after treatment, and ENoG at 6~8 days after onset & EMG showed statistically higher correlation than that at 3~5 day after onset. Conclusions : We could get the evidence of the validity of EMG and early-performed ENoG as predicting factor for facial palsy based on collaborative treatment between Korean and western medicine.

Effect of Functional Beverage on Weight Control and Body Fat Mass in Overweight Women

  • Chae, Jey-Sook;Lee, Jong-Ho;Koh, Soo-Jeong;Jang, Yong-Soo;Lee, Jin-Hee
    • Biomolecules & Therapeutics
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    • v.11 no.4
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    • pp.257-264
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    • 2003
  • Carnitine, hydroxycitric acid, and soy peptide have been known to be anti-obesity agents. The purpose of this study was to evaluate the combined effects of carnitine, hydroxycitric acid, and soy peptide mixture as a potential anti-obesity supplement in overweight women. Overweight premenopausal women (n=33; PIBW>110; 20 to 39 years) were randomized into two groups: the placebo group and the functional beverage group (the test group). Functional beverage was composed of 2000 mg soy peptide, 20 mg L-carnitine and 300 mg garcinia(40% hydroxycitric acid). Body weight and 3 day food dimes, biochemical measurements and computerized tomography were measured at baseline and 8-week. After 8-week consumption of functional beverage with usual diet and exercise, body weight fell an average of 1.4 kg (2.1%). Visceral fat area reduced an average of 7.8% at L1($69.6{\pm}8.7\;vs\;64.2{\pm}7.5\;\textrm{cm}^2$) and 5.1% ($60.7{\pm}4.9\;vs\;57.6{\pm}4.8\;\textrm{cm}^2$, p<0.05) at L4level after weight loss in the test group. Calf fat area in the test group showed about 10% reduction ($31.0{\pm}2.7\;vs=\;27.7{\pm}1.7\;\textrm{cm}^2$, p<0.05) after weight loss. These reductions in fat areas were not shown in the placebo group. There were tendencies of increase in serum levels of $\beta-hydroxybutyrate$, acetoacetate, and total ketones in the test group. There were 7% and 17% insignificant increase in fasting free fatty acid (FFA) and response area of FFA during oral glucose tolerance test(OGTT), respectively, in this group. ill addition, little weight loss in the test group showed 8% but not significant reduction in insulin response area during OGTT. In conclusion, this study shows that taking a mixture of carnitine, hydroxycitric acid, and soy peptide as a potential anti-obesity supplement for 8-week produced advantageous changes in the weight and visceral fat accumulation of overweight women.

Propagation Characteristics and Tolerance Analysis of Optical Wires in Flexible Optical PCB by Ray Tracing (연성 광 PCB용 광 배선의 손실특성 및 제작 공차 분석)

  • Yeom, Jun-Cheol;Park, Dae-Seo;Kim, Young-Seok;Kim, Dae-Chan;Park, Se-Geun;O, Beom-Hoan;Lee, El-Hang;Lee, Seung-Gol;Jeon, Keum-Soo
    • Korean Journal of Optics and Photonics
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    • v.19 no.4
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    • pp.255-261
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    • 2008
  • In this study, the propagation characteristics and the fabrication tolerance of an optical wire in a flexible optical PCB were analyzed by using a ray-tracing method. It is found from the analysis that the sidewall angle of a core should be controlled within $1^{\circ}$ in order to maintain the propagation loss to less than -1 dB/mm, and that the bending radius of the optical wire should be larger than 5 mm in order to suppress the bending loss below -1 dB. In addition, it is confirmed that the lateral misalignment of ${\pm}15\;{\mu}m$, and the angular tilting of VCSEL of $6^{\circ}$ are allowable for the coupling loss of -1 dB.