• Journal of Astronomy and Space Sciences
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• v.12 no.2
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• pp.179-195
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• 1995

RT Per has been known as a close binary of which the orbital period has unpredictably varied so far. Although there are no agreements with the working mechanism for the changes of the period, two interpretations have been suggested and waiting for to be tested: 1) light-time effects due to the unseen 3rd and 4rd bodies (Panchatsaram 1981), 2) Abrupt period-changes, due to internal variations of the system (e.g. mass transfer or mass loss) superimposing to the light-time effect by a 3rd body (Frieboes-Conde & Herczeg 1973). In the point of view that the former interprepation models could predict the behavior of the changes of the orbital period theoretically, we checked whether the recent observed times of minimum lights follow the perdictions by the first model or not. We confirmed that the observed times of minimum lights have followed the variations calculated by the light-times effects due to the 3rd and 4rd bodies suggested by Panchatsatam. In this paper a total of 626 times of minimum lights were reanalyzed in terms of the light-time effects by the 3rd and 4rd bodies. We concluded that the eclipsing pair in SVCam system moves in an elliptic orbit about center of mass of the triple system with a period of about $42.^y2$, while the mass center of the triplet is in light-time orbit about the center of mass of the quadruple system with a period of $120^y$. The mean masses deduced for the 3rd and 4rd bodies were $0.89m_\odot$ and $0.82m_\odot$, respectively.

• Wind and Structures
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• v.21 no.6
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• pp.727-753
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• 2015

A double-skinned composite tubular (DSCT) wind power tower was suggested and automatic section design software was developed. The developed software adopted the nonlinear material model and the nonlinear column model. If the outer diameter, material properties and design capacities of a DSCT wind power tower are given, the developed software performs axial force-bending moment interaction analyses for hundreds of sections of the tower and suggests ten optimized cross-sectional designs. In this study, 80 sections of DSCT wind power towers were designed for 3.6 MW and 5.0 MW turbines. Moreover, the performances of the 80 designed sections were analyzed with and without considerations of large displacement effect. In designing and analyzing them, the material nonlinearity and the confining effect of concrete were considered. The comparison of the analysis results showed the moment capacity loss of the wind power tower by the mass of the turbine is significant and the large displacement effect should be considered for the safe design of the wind power tower.

• Journal of Microbiology and Biotechnology
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• v.25 no.10
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• pp.1702-1708
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• 2015

We have developed a new shuttle plasmid, designated as pLK1-MCS that can replicate in both Clostridium acetobutylicum and Escherichia coli, by combining the pUB110 and pUC19 plasmids. Plasmid pLK1-MCS replicated more stably than previously reported plasmids containing either the pIM13 or the pAMβ1 replicon in the absence of antibiotic selective pressure. The transfer frequency of pLK1-MCS into C. acetobutylicum was similar to the transfer frequency of other shuttle plasmids. We complemented C. acetobutylicum ML1 (that does not produce solvents such as acetone, butanol, and ethanol owing to loss of the megaplasmid pSOL1 harboring the adhE1-ctfAB-adc operon) by introducing pLK1-MCS carrying the adhE1-ctfAB-adc operon into C. acetobutylicum ML1. The transformed cells were able to resume anaerobic solvent production, indicating that the new shuttle plasmid has the potential for practical use in microbial biotechnology.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.27 no.11
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• pp.37-46
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• 2013

This paper proposes the boost type bidirectional zero current switching(ZCS) DC/DC converter of transformer series construction for electric vehicle operation using low voltage battery. This converter can high boost through the double voltage circuit and series construction of output part using two converters. This converter system has the advantages that bidirectional power transfer is excellent, size and making of transformer because of this converter keeps the transformation ratio to 1:1. Proposed DC/DC converter uses the ZCS method to decrease the switching loss. By replacing reactance ingredients of L-C resonance circuit for ZCS with leakage inductance ingredients of high frequency transformer and half-bridge capacitor it reduces system size and expense because of not add special reactor. It can confirm to output of high voltage to operate the electric vehicle with low voltage of input and operation of ZCS in all load region through the result of PSIM simulation and experiment.

• The Korean Journal of Physiology and Pharmacology
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• v.2 no.5
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• pp.565-572
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• 1998

The present study was to evaluate the protective effects of bromocriptine, which is known as $D_2$ dopamine receptor agonist and used for the treatment of patients with Parkinson's disease (PD), on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in vitro and in vivo. Lipid peroxidation product (malondialdehyde; MDA) produced by the administration of 6-OHDA was profoundly reduced following the treatment of bromocriptine in a dose-dependent manner in rabbit brain homogenate. Quinone formation by 6-OHDA autoxidation was also attenuated, and its effect was as potent as other antioxidants. Pretreatment of bromocriptine reduced the cytotoxicity of 6-OHDA on SH-SY5Y neuroblastoma cell lines dose-dependently. The loss of striatal dopamine and its metabolite, DOPAC (dihydroxyphenylacetic acid) as well as increase of MDA production caused by intrastriatal injection of 6-OHDA was significantly recovered following the treatment of bromocriptine. The present study clearly showed that bromocriptine had a protective action against 6-OHDA-induced neurotoxicity. These results suggest that bromocriptine has the antioxidant properties, which could be another advantage for delaying the progress of Parkinson's disease.

• The Transactions of the Korean Institute of Power Electronics
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• v.23 no.3
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• pp.208-216
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• 2018

In this paper, an LLC resonant converter employing two coupled inductors on the secondary side of the converter is proposed. The conventional LLC converter exhibits serious power loss during secondary winding of the transformer because of generation of tremendous output current ripples. To overcome this problem, an LLC resonant converter with a current doubler as a rectifying circuit was recently proposed. However, the current-doubler rectifying circuit requires coupled inductors with a high coupling ratio to retain the designed resonance characteristics. Therefore, an additional hardware filter is required at the output stage to address large output current ripples. Additional design procedures are also necessary because the inductance component of the added filter affects the designed resonant network. To solve this issue, an LLC resonant converter employing two coupled inductors is proposed in this paper. Mathematical analysis shows that the proposed secondary-side current-doubler circuit does not affect the designed resonance characteristics. The operating principles and theoretical analyses are proven through a simulation and experiments with a 54 V/28 A prototype.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.4
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• pp.9-17
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• 1998

BiNbO$_{4}$ ceramics with 0.07wt% V$_{2}$O$_{5}$ and 0.03wt% CuO (BNC3V7) sintered at 900 .deg. C where it is possible for these to be co-fired with ag electronde. Dielectric constant of 44.3 TCF (Thermal Coefficient of resonance Frequency) of 2 ppm/.deg. C and Qxf value 22,000 GHz can be obtained from BNC3V7. the laminatedchip LC filter is indispensible to the minimaturization of PCS (Personal Communication System) terminals. Therefore, multilayer type BPF has been fabricated by screen-printing with silver electrode after tape casting. The simulated characteristics of the fabricated filters sintered at 900.deg. C werecomparedwith the designed ones. for Band Pass Filter widths was similar that ofdesigned ones. For Low Pass Filter (LPF), insertion loss value of band pass widths (2.4 dB) which is a few higher than that of designed (1dB), but characteristization of band pass widths was similar that of designed ones.s.of designed ones.s.

• BMB Reports
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• v.33 no.3
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• pp.234-241
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• 2000

A new type of the human TSA homologous gene was cloned from a HeLa cell cDNA and characterized. The gene product consists of 161 amino acids with a molecular mass of 16,900. The TSA homologous protein, as a new 6th member of the human TSA (hTSA VI), exerted a thioldependent peroxidase activity with the use of thioredoxin system as a physiological electron donor. The values of $V_{max}/K_m$ of hTSA VI for $H_2O_2$ and t-butyl hydroperoxide (t-BOOH) were calculated as $5.53{\times}10^{-2}$ and $3.70{\times}10^{-2}$, respectively. This implies that hTSA VI is a peroxidase, which reduces $H_2O_2$ and t-BOOH. The mutation of $Cys^{47}$ to serine resulted in a complete loss of the peroxidase activity. This suggests that $Cys^{47}$ acts as a primary site of catalysis. The analysis of the tryptic digest derived from hTSA VI revealed that the $Cys^{47}$ exists as a free thiol form. Taken together, these results suggest that the TSA homologous protein is a new type of the human family, which exerts thioredoxin-linked peroxidase activity toward $H_2O_2$ and alkyl hydroperoxide.

• Biomedical Science Letters
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• v.15 no.3
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• pp.241-247
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• 2009

Wound healing is a complex and highly organized biological response to injury that results in the loss of tissue integrity. Our particular interest was propolis, traditional used as an antimicrobial and an anti-inflammatory agent. The purpose of this study was to see the effects of propolis on healing of the laser induced wounds and the level of collagen formation. 808 nm laser (20 J) was irradiated on the back of rats. Irradiated wounds were divided into gel control and 6 experimental groups (3 and 5% of different three kinds of propolis). Gel type of propolis (supplied by Seoul Propolis Co., Daejeon, Korea) in water based were applied on the laser wound once daily for 14 days. One fourth of rats were sacrificed on $3^{rd}$, $7^{th}$, $10^{th}$, and $14^{th}$ day and each wound was evaluated for degree of wound healing and the level of collagen formation. Healing of wound was evaluated by measuring and comparing the width and depth of the wounds. The levels of collagen were increased in 3 and 5% gel groups comparing to control on $3^{rd}$ day and the collagen level were increased more on $7^{th}$ day. Wounds of the experimental groups showed better healing in width comparing to the healing of the control. The results of this study demonstrated that propolis accelerated healing of wounds induced by laser irradiation and good collagen formation.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.4
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• pp.264-270
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• 2018

Purpose: The aim of this study was to describe functional gastrointestinal disorders (FGID) presented in a tertiary medical center, characteristics of patients and results of the diagnostic work-up together with an outcome during the follow up. Methods: This was a retrospective, single center, observational study including all patients who were diagnosed with FGID based on Rome III criteria from January to December 2015 in tertiary medical center. Results: Overall 294 children were included (mean age, 8.9 years [range, 1-18 years]; 165 females). Majority had functional constipation (35.4%), followed by functional abdominal pain (30.6%), irritable bowel syndrome (17.0%), functional dyspepsia (12.6%), functional nausea (3.4%) and abdominal migraine (1.0%). Regression model found that only significant factor associated with improvement of symptoms is the establishment of the functional diagnosis at the first visit (hazard ratio, 2.163; 95% confidence inverval, 1.029-4.544). There was no association between improvement of symptoms and presence of alarm signs/symptoms (weight loss, nocturnal symptoms and severe vomiting) at diagnosis. Furthermore, in pain symptoms (functional abdominal pain, irritable bowel syndrome, dyspepsia) no treatment positively correlated with pain improvement. Conclusion: Regardless of the initial diagnosis of FGID, positive diagnosis at the first visit increases a chance for resolution of symptoms.