• Proceedings of the Korean Operations and Management Science Society Conference
• /
• 1994.04a
• /
• pp.291-300
• /
• 1994

In this paper we consider the frequency assignment problem (FAP) in a cellular mobile communication system which has a maximal distance of channel interference. This special structure is observed in most cellular systems. To handle the considered FAP, we use the pattern approach which fits naturally to the problem. Based on this approach, we are able to formulate the considered FAP into a manageable optimization problem and propose a two phase heuristic algorithm for the problem. Computational experiments show that our algorithm performs much better in both solution quality and computational time than the recently developed algorithms for FAP. Since the considered FAP well reflects most cellular systems, our algorithm can be applied to many practical situations.

• Journal of Mechanical Science and Technology
• /
• v.16 no.1
• /
• pp.94-101
• /
• 2002

Convection-dominated melting in a rectangular cavity is analyzed numerically with particular attention to the multi-cellular flows in the melt. At the earlier stage of the melting, the melt region is quite similar to a cavity with high aspect rati71, where the multi-cellular natural convection appears. Numerical results show that the formation and evolution of the multiple flow cells in the melt region is approximately similar to t]tat of a single-phase flow in a tall cavity with the same aspect ratio; however, the continuous change of the melt region due to the melting affects the detailed process. Also, numerical aspects for the prediction of the detailed flow structure in the melt are discussed.

• Steel and Composite Structures
• /
• v.49 no.4
• /
• pp.393-405
• /
• 2023

In this paper, the energy absorption capability of a novel cruciform composite lattice structure was evaluated through the simulation of compression tests. For this purpose, several test samples of Polylactic acid cellular reinforced with continuous glass fibers were prepared for compression testing using the additive manufacturing method of material extrusion. Using a conventional path design for material extrusion, multiple debonding is probable to be occurred at the joint regions of adjacent cells. Therefore, an innovative printing path design was proposed for the cruciform lattice structure. Afterwards, quasistatic compression tests were performed to evaluate the energy absorption behaviour of this structure. A finite element model based on local material property degradation was then developed to verify the experimental test and extend the virtual test method. Accordingly, different combinations of unit cells' dimensions using the design of the experiment were numerically proposed to obtain the optimal configuration in terms of the total absorbed energy. Having brilliant energy absorption properties, the studied cruciform lattice with its optimized unit cell dimensions can be used as an energy absorber in crashworthiness applications. Finally, a cellular structure will be suitable with optimal behavior in crush load efficiency and high energy absorption.

• BMB Reports
• /
• v.34 no.4
• /
• pp.355-364
• /
• 2001

Major human Nucleoside diphosphate kinases (NDPKs) exist as hetero-oligomers, consisting of NDPK-A and NDPK-B, rather than homo-oligomer. To investigate their biological function depending on the oligomeric structure in vivo, we characterized the biochemical properties of cellular NDPK. Cellular NDPKs, which are made up of a unique combination of isoforms, were purified from human erythrocyte and placenta. We found that cellular NDPK and recombinant isoforms NDPKs have their own distinct biochemical properties in autophosphorylation, stability toward heat or urea, and DNA binding. Cellular NDPK was found to have unique characteristics rather than the expected additive properties of recombinant isoforms. The mutations in the dimeric interface of NDPK-B (R34G, N69H or K135L) caused defective DNA binding and simultaneously reduced the enzymatic stability These results suggest that the oligomeric interaction could play a major role in the stability of catalytic domain and might be related to the regulation of various cellular functions of NDPK.

• Molecules and Cells
• /
• v.43 no.3
• /
• pp.222-227
• /
• 2020

Inositol polyphosphate multikinase (IPMK) is required for the biosynthesis of inositol phosphates (IPs) through the phosphorylation of multiple IP metabolites such as IP3 and IP4. The biological significance of IPMK's catalytic actions to regulate cellular signaling events such as growth and metabolism has been studied extensively. However, pharmacological reagents that inhibit IPMK have not yet been identified. We employed a structure-based virtual screening of publicly available U.S. Food and Drug Administration-approved drugs and chemicals that identified the antidepressant, vilazodone, as an IPMK inhibitor. Docking simulations and pharmacophore analyses showed that vilazodone has a higher affinity for the ATP-binding catalytic region of IPMK than ATP and we validated that vilazodone inhibits IPMK's IP kinase activities in vitro. The incubation of vilazodone with NIH3T3-L1 fibroblasts reduced cellular levels of IP5 and other highly phosphorylated IPs without influencing IP4 levels. We further found decreased Akt phosphorylation in vilazodone-treated HCT116 cancer cells. These data clearly indicate selective cellular actions of vilazodone against IPMK-dependent catalytic steps in IP metabolism and Akt activation. Collectively, our data demonstrate vilazodone as a method to inhibit cellular IPMK, providing a valuable pharmacological agent to study and target the biological and pathological processes governed by IPMK.

• Molecules and Cells
• /
• v.45 no.8
• /
• pp.534-536
• /
• 2022

• Molecules and Cells
• /
• v.46 no.6
• /
• pp.345-347
• /
• 2023

• Journal of KIISE:Information Networking
• /
• v.29 no.3
• /
• pp.299-313
• /
• 2002

Recently, the demand for mobile communications and multimedia services has rapidly increased so that conventional cellular system cannot fulfill the requirement of users (capacity and QoS) any more. Therefore, the hierarchical cellular system has been suggested in order to guarantee the QoS and to admit large population of users. IMT-2000 adopts the hierarchical cellular structure, which requires a call control algorithm capable of manipulating and utilizing the complicated structure of hierarchical cellular structure with handiness and efficiency. In this thesis, as an improvement of conventional combined algorithm, a new call control algorithm considering the moving speed of terminal and bandwidth is suggested. This algorithm employs buffers and guard channels to reduce the failure rate. Also, this algorithm considers the moving speed of terminal and bandwidth to elevate the efficiency. Furthermore, calls are handled separately according to the moving speeds of terminal and bandwidths to improve the QoS and reduce the handover rate. As an evaluation of the suggested algorithm, a model hierarchical cellular system is constructed and simulations are conducted with various types of traffic. As the result of the simulations, such indices as block rate, drop rate, channel utilization, and the number of inter layer handovers are examined to demonstrate the excellency fo the suggested algorithm.

• Journal of Environmental Health Sciences
• /
• v.38 no.3
• /
• pp.213-222
• /
• 2012

Objectives: This study was undertaken in order to evaluate by work space zoning and structure the concentrations of biological contaminants in the indoor air of domestic office buildings. Methods: Air samples were collected in the office spaces of 15 office buildings in Seoul from June 28 to July 28, 2011. Prior to the sampling, each office was classified into 'open-plan office', 'cellular office' and 'mixed office' according to the work space zoning. To evaluate the biological contamination of indoor air, total suspended bacteria (TSB), Gram positive bacteria (GPB), Staphylococcus aureus (S.A), Methicillin-resistant Staphylococcus aureus (MRSA), Gram negative bacteria (GNB) and fungi were investigated. During the sampling, temperature, relative humidity and carbon dioxide ($CO_2$) were measured. Results: The TSB concentrations ($GM{\pm}GSD$) were $452({\pm}1.3)cfu/m^3$ in open-plan offices, $366({\pm}1.3)cfu/m^3$ in cellular offices and $287({\pm}1.5)cfu/m^3$ in mixed offices, and there were significant differences between the three groups (p<0.05). The highest concentrations ($GM{\pm}GSD$) of fungi were found in the indoor air of cellular offices $128({\pm}1.0)cfu/m^3$, which was at least three times higher than the concentrations in mixed offices $43({\pm}1.0)cfu/m^3$ (p<0.05). Conclusions: Microbiological contamination in the indoor air of office buildings by work space structure was the highest with the open-plan office layout which includes no high walls or doors separating the occupants.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.18 no.7
• /
• pp.774-783
• /
• 2007

This paper presents an integrated packaging antenna-diplexer module for wireless communication systems in the Cellular and SDMB band. The design and the realization of the proposed one are experimentally analyzed and discussed. It consists of a dual-resonance antenna and a diplexer with a multi-layer LTCC(${\varepsilon}_r=7.8,\;tan\;{\delta}=0.0043$) technology with integration capability and low loss. The dual-resonance antenna of the proposed module has the meander line structure for size reduction and has the shorting structure of an inverted F antenna to achieve good impedance matching. The diplexer of the proposed module was designed with the combination of low pass filter(LPF) and high pass filter(HPF). Decreasing the mutual interference between them provides a high isolation characteristic. The proposed antenna-diplexer module with dimensions of $27.5{\times}12.0{\times}2.2mm$ operates within a range from 813 MHz to 902 MHz for the cellular band and from 2,586 MHz to 2,655 MHz for the SDMB band. And the measured gain of the fabricated module is -1.96 dBi for Cellular band and -5.43 dBi for SDMB band. The parameters for the antenna-diplexer module are investigated and the several performances are discussed.