• 센서학회지
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• 제18권4호
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• pp.251-262
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• 2009

Biosensors exploit the specific binding between recognition molecule on the biosensor surface and target molecule in analyte and are used in the detection of specific biomolecules such as protein, DNA, cell, virus, etc., with a view towards developing analytical devices. Recently, application field of biosensors have been expanding from diagnosis to biodefense because they can basically serve as high performance devices. This review describes the basic information of biosensors including definition, classification, and operational principle. Moreover, we introduce micro/nano technology-based biosensors with better detection performance than traditional method and their application examples.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제51권6호
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• pp.240-245
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• 2002

In this paper, a novel optical measuring system for the measurement of nonuniform electric field was proposed. The electric field distorted by the discharges was detected through proposed optical measuring system based on the Pockets effect and Mach-Zehnder interferometer. In order to produce distorted electric field, corona discharge was generated from needle-plane electrode in air and detected by optical measuring system. This optical measuring system is constructed by He-Ne laser, single mode optical fiber, $2{\times}2$ 50/50 beam splitter, $LiNbO_3$ Pockets cell, photo detector and PC. In this system, output signal of Pockels sensor is measured by digital oscilloscope and transferred to the PC for recording and statistical processing. Through this paper, a promising possibilities of proto-type optical measuring system were evinced.

• 한국식품저장유통학회지
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• 제1권1호
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• pp.37-43
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• 1994

A microcomputer system consisting of 16-bit microcomputer, PCL-711S interface board, censors, and converters have been set up in order to automatically measure temperature, humidity and weight loss which are major variables of storage of apple. This system was operated by PC-LabDAS software. It has been possible to measure continuously the weight loss of Fuji apple stored in CA with the weight converter made by a miniature load cell and a strain amplifier. The temperature was checked by a k-type thermocouple and Pt 100 $\Omega$ RTD, and humidity by PQ653JAl humidity sensor. It has been possible to set up a linear equation which showers high correlationship between the estimate of temperature, weight humidity and the output of the converter in that r2 is more than 0.99. Transpiration rate, a significant factor of quality deterioration for CA storage of apple, can be estimated with these values.

• 한국전자통신학회논문지
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• 제8권8호
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• pp.1247-1255
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• 2013

본 논문에서는 기존에 매설된 기준점의 문제점을 분석 및 보완하기 위해서 경관 조명, 실시간 데이터 수집, 주변 지각변동의 모니터링이 가능한 LED 및 자이로센서 기반의 다기능 전자측량기준점 프로토타입 시스템을 제안한다. 제안하는 시스템의 H/W는 지각변동 감지를 위해서 자이로센서모듈을 탑재하고, 위치정보를 처리하기 위한 GPS모듈, 전자측량기준점의 주변 환경 데이터를 처리하기 위한 환경 센서 모듈을 이용하여 센서값을 데이터화하고 수집된 데이터를 CDMA 무선 통신으로 서버로 전송이 가능하도록 하였다. 아울러 전자측량 기준점의 H/W 활용을 높이기 위해 전자측량기준점 H/W의 외관에 LED 및 QR코드, RFID, 태양광모듈을 적용시켜 시스템 관리 및 사후 활용성 높이고자 한다. 마지막으로 본 논문에서 제안한 다기능 전자측량기준점에 다양한 기능이 포함되어 있어 안정적인 전력 공급을 위한 전류량 평가를 실시하였고, 측정 결과 전력 소실률이 2.29%로 비교적 안정적인 운영이 가능한 결과를 확인하였다. 그리고 제안된 전자측량기준점의 우수성을 평가하기 위해 기존에 연구된 전자측량기준점 시스템과의 정성적인 비교평가를 실시하였다.

• 대한전자공학회논문지SP
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• 제44권5호
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• pp.103-111
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• 2007

본 논문에서는 single-chip CMOS Image Sensor(CIS)용 고화질 image signal processor(ISP)에 최적화된 하드웨어 구조를 제안한다. Single-chip CIS는 CIS와 ISP가 하나의 칩으로 구현된 것으로, 다양한 휴대기기에 사용된다. 휴대기기의 특성상, single-chip CIS용 ISP는 고화질이면서도 저전력을 위해 하드웨어 복잡도를 최소화해야 한다. 영상의 품질 향상을 위해서 다양한 영상 처리 블록들이 ISP에 적용되지만, 그 중에 핵심이면서 하드웨어 복잡도가 가장 큰 블록은 컬러 영상을 만들기 위한 색 보간 블록과 영상을 선명하게 하기 위한 화질 개선 필터 블록이다. 이들 블록은 데이터 처리를 위한 로직 외에도 라인 메모리를 필요로 하기 때문에 ISP의 하드웨어 복잡도의 대부분을 차지한다. 기존 ISP에서는 색 보간과 화질 개선 필터를 독립적으로 수행하였기 때문에 많은 수의 라인 메모리가 필요하였다. 따라서 하드웨어 복잡도를 낮추기 위해서는 낮은 성능의 색보간 알고리즘을 적용하거나, 화질 개선 필터를 사용하지 않아야 했다. 본 논문에서는 화질 개선을 위해 경계 적응적이면서 채널간 상관관계를 고려하는 고화질 색 보간 알고리즘을 적용하였다. 또한 채널 간 상관관계를 고려하는 색 보간 알고리즘의 특성을 이용하여 색 보간 블록과 화질 개선 필터 블록이 라인 메모리를 공유하도록 설계함으로써, 전체 라인 메모리 수를 최소화하는 새로운 구조를 제안한다. 제안된 방법을 적용하면 화질 개선 필터 블록을 위한 추가적인 라인 메모리가 불필요하기 때문에, 고화질과 낮은 복잡도 모두를 만족시킬 수 있다. 제안 방식과 기존 방식의 MSE(Mean Square Error)는 0.37로, 메모리 공유로 인한 화질의 저하는 거의 없었고, 고화질 색 보간 알고리즘을 적용했기 때문에 전체적인 화질은 향상되었다. 제안된 ISP 구조는 Verilog HDL 및 FPGA를 이용하여 실시간으로 구현 검증되었다. 0.25um CMOS 표준 셀 라이브러리를 이용하여 합성하였을 때, 총 게이트 수는 37K개였으며 7.5개의 라인 메모리가 사용되었다.

• Nuclear Engineering and Technology
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• 제52권9호
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• pp.2025-2033
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• 2020

Signature-based safeguards (SBS) is being developed to assist tradition nuclear material accountancy methods in tracking material in pyroprocessing facilities. SBS involves identifying off-normal scenarios that would result in improper movement of material in a pyroprocessing facilities and determining associated sensor response signatures. SBS investigations are undertaken in the computational space utilizing an electrochemical transport code known as enhanced REFIN with anodic dissolution (ERAD) to calculate the affect of off-normal conditions in the electrorefiner (ER) on material movement. Work is undertaken to experimentally validate the predictions and assumptions made by ERAD for off-normal occurrences. These experiments were undertaken on a benchtop scale and involved operating an electrochemical cell at 10 separate current densities for constant current operations to deposit U and Gd at a W cathode. These experiments were then modeled using ERAD to compare calculated predictions versus analytical experimental results it was found. It was discovered both the experimental and calculated results reflect a trend of increased codeposition of U and Gd with increasing current density. ERAD was thus demonstrated to be useful for predicting trends from anomalous operation but will require further optimization to be utilized as a quantitative design tool.

• Journal of Astronomy and Space Sciences
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• 제32권4호
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• pp.419-425
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• 2015

In this study, a new idea for developing a space scale for measuring mass in a microgravity environment was proposed by using the inertial force properties of an object to measure its mass. The space scale detected the momentum change of the specimen and reference masses by using a load-cell sensor as the force transducer based on Newton's laws of motion. In addition, the space scale calculated the specimen mass by comparing the inertial forces of the specimen and reference masses in the same acceleration field. By using this concept, a space scale with a capacity of 3 kg based on the law of momentum conservation was implemented and demonstrated under microgravity conditions onboard International Space Station (ISS) with an accuracy of ${\pm}1g$. By the performance analysis on the space scale, it was verified that an instrument with a compact size could be implemented and be quickly measured with a reasonable accuracy under microgravity conditions.

• 센서학회지
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• 제29권2호
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• pp.100-104
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• 2020

Thus far, several in vivo biosensing platforms have been proposed to measure the mechanical contractility of cultured cardiomyocytes. However, the low sensitivity and screening rate of the developed sensors severely limit their practical applications. In addition, intensive research and development in cardiovascular disease demand a high-throughput drug-screening platform based on biomimetic engineering. To overcome the drawbacks of the current state-of-the-art methods, we propose a high-throughput drug-screening platform based on 16 functional high-sensitivity well plates. The proposed system simulates the physiological accuracy of the heart function in an in vitro environment. We fabricated 64 cantilevers using highly flexible and optically transparent silicone rubber and placed in 16 independent wells. Nanogrooves were imprinted on the surface of the cantilever to promote cell alignment and maturation. The adverse effects of the cardiovascular drugs on the cultured cardiomyocytes were systematically investigated. The 64 cantilevers demonstrated a highly reliable and reproducible mechanical contractility of the drug-treated cardiomyocytes. Real-time high-throughput screening and simultaneous evaluation of the cardiomyocyte mechanical contractility under multiple drugs verified that the proposed system could be used as an efficient drugtoxicity test platform.

• 자동차안전학회지
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• 제9권2호
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• pp.6-12
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• 2017

An autonomous driving system based on a precise digital map is developed. The system is implemented to the Hyundai's Tucsan fuel cell car, which has a camera, smart cruise control (SCC) and Blind spot detection (BSD) radars, 4-Layer LiDARs, and a standard GPS module. The precise digital map has various information such as lanes, speed bumps, crosswalks and land marks, etc. They can be distinguished as lane-level. The system fuses sensed data around the vehicle for localization and estimates the vehicle's location in the precise map. Objects around the vehicle are detected by the sensor fusion system. Collision threat assessment is performed by detecting dangerous vehicles on the precise map. When an obstacle is on the driving path, the system estimates time to collision and slow down the speed. The vehicle has driven autonomously in the Hyundai-Kia Namyang Research Center.

• The Korean Journal of Physiology and Pharmacology
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• 제23권4호
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• pp.237-249
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• 2019

Confirming the direct link between neural circuit activity and animal behavior has been a principal aim of neuroscience. The genetically encoded calcium indicator (GECI), which binds to calcium ions and emits fluorescence visualizing intracellular calcium concentration, enables detection of in vivo neuronal firing activity. Various GECIs have been developed and can be chosen for diverse purposes. These GECI-based signals can be acquired by several tools including two-photon microscopy and microendoscopy for precise or wide imaging at cellular to synaptic levels. In addition, the images from GECI signals can be analyzed with open source codes including constrained non-negative matrix factorization for endoscopy data (CNMF_E) and miniscope 1-photon-based calcium imaging signal extraction pipeline (MIN1PIPE), and considering parameters of the imaged brain regions (e.g., diameter or shape of soma or the resolution of recorded images), the real-time activity of each cell can be acquired and linked with animal behaviors. As a result, GECI signal analysis can be a powerful tool for revealing the functions of neuronal circuits related to specific behaviors.