• Title/Summary/Keyword: Cell-Based

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Research trends and development direction in cell-based seafood (배양수산물의 연구현황 및 발전방향)

  • Jung, Jin-Kyoung;Park, Young-Min;Kim, Sang-Gu;Lee, Sang-Yoon
    • Food Science and Industry
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    • v.55 no.1
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    • pp.95-104
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    • 2022
  • Climate change due to global warming is affecting the global environment. The fishery industry is highly dependent on the natural environment, so the fishery industry is increasingly volatile due to the rapidly changing climate change. At the same time, consumers' anxiety due to marine pollution such as microplastics, radioactivity, and heavy metals are increasing. Accordingly, cell-based seafood are being proposed as an alternative for the sustainable use of seafood resources. Cell-based seafood manufactured through a process of differentiation and proliferation using cells isolated from actual seafood and cell, scaffold, media, and bioreactor technologies are organically connected to each other. This review summarizes the latest research status of cell-based seafood. Based on this, suggests a development direction for cell-based seafood to properly settle in the future market.

Performance Evaluation of Distance-based Registration Considering Cell-by-Cell Location Area (셀 단위로 증가하는 위치영역을 고려한 거리기준 위치등록의 성능 평가)

  • Baek, Jang-Hyun;Park, Jin-Won
    • Journal of Korean Institute of Industrial Engineers
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    • v.34 no.2
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    • pp.151-159
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    • 2008
  • An efficient location registration scheme is essential to accommodate continuously increasing mobile subscribers and to offer a variety of multimedia services with good quality. In this study, we consider a distance-based registration scheme where the number of location areas varies on the basis of cell-by-cell, not of ring-by-ring, to analyze the optimal size of the location area. Using our proposed cell-by-cell distance-based registration scheme with random walk mobility model, we analyze a variety of circumstances to obtain the optimal number of cells for location area that minimizes total signaling traffic on radio channels. From our analysis results, we show that the optimal number of cells for location area is between 4 and 6 in most cases, and our cell-by-cell distance-based location registration scheme has less signaling traffic than optimal ring-by-ring distance-based location registration scheme where optimal distance threshold is 2 (thus the optimal number of cells for location area is 7).

Parallel Scrambling Techniques for SDH and ATM Transmissions (SDH와 ATM 전송을 위한 병렬혼화 기법)

  • 김석창;이병기
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.18 no.8
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    • pp.1146-1158
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    • 1993
  • In this paper, parallel scrambling techniques are considered for practical use in the SDH transmission and the ATM transmission. In the ATM transmission, there are two ways of transmitting ATM cells - the SDH-based and the cell-based - and the corresponding scrambling techniques differ accordingly. For the SDH transmission and the SDH-based ATM transmission, the FSS (frame synchronous scrambling) is applied to the STM frames : while for the cell-based ATM trans-mission, the DSS(distributed sample scrambling) is used on the ATM cell stream. The parallel scrambling techniques are examined for the FSS and the DSS, and applied to achieve the parallel FSSs for use in the SDH and the SDH-based ATM transmission along with the parallel DSS applicable to the cell-based ATM transmission. The resulting(8, 4) PSRG(parallel shift resister generator) and (8, 16) PSRG based parallel scramblings are directly applicable for the STM-1 rate processing of the STM-4 and STM-16 scramblings, respectively. Likewise, the resulting (1, 8)PSRG and double-sampling-double-correction based parallel scrambling techniques can be practically used for a low-rate processing of the SDH-based and the cell-based ATM signal scrambling respectively.

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Microscopic Image-based Cancer Cell Viability-related Phenotype Extraction (현미경 영상 기반 암세포 생존력 관련 표현형 추출)

  • Misun Kang
    • Journal of Biomedical Engineering Research
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    • v.44 no.3
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    • pp.176-181
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    • 2023
  • During cancer treatment, the patient's response to drugs appears differently at the cellular level. In this paper, an image-based cell phenotypic feature quantification and key feature selection method are presented to predict the response of patient-derived cancer cells to a specific drug. In order to analyze the viability characteristics of cancer cells, high-definition microscope images in which cell nuclei are fluorescently stained are used, and individual-level cell analysis is performed. To this end, first, image stitching is performed for analysis of the same environment in units of the well plates, and uneven brightness due to the effects of illumination is adjusted based on the histogram. In order to automatically segment only the cell nucleus region, which is the region of interest, from the improved image, a superpixel-based segmentation technique is applied using the fluorescence expression level and morphological information. After extracting 242 types of features from the image through the segmented cell region information, only the features related to cell viability are selected through the ReliefF algorithm. The proposed method can be applied to cell image-based phenotypic screening to determine a patient's response to a drug.

Influence of the Thickness and Doping Concentration in p- and n-Type Poly-Si Layers on the Efficiency of a Solar Cell Based on a Carbon Fiber

  • Yoon, Min-Seok;Shim, Young Bo;Han, Young-Geun
    • Journal of the Optical Society of Korea
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    • v.19 no.2
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    • pp.199-205
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    • 2015
  • We investigated the effects of the thickness and doping concentration in p- and n-type poly-Si layers on the performance of a solar cell based on a carbon fiber in order to improve the energy conversion efficiency of the cell. The short-circuit current density and open-circuit voltage of the carbon fiber-based solar cell were significantly influenced by the thickness and doping concentration in the p- and n-type poly-Si layers. The solar cell efficiency was successfully enhanced to ~10.5%.

The Impedance Properties of Poly(p-phenylene)-based Carbon/Li cell (PPP-based Carbon/Li cell의 임피던스 특성)

  • 류현옥;홍성문;김주승;구할본
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1997.11a
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    • pp.283-285
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    • 1997
  • We have obtained disordered carbon by pyrolyzing PPP in a nitrogen atmosphere for 8 hour at 700$^{\circ}C$. AC impedance property was measured with the PPP-based carbon/EC-DEC/Li cell. The impedance spectra of the cell were measured during the 1st discharge proceed. As the result of measurement the cell resistance decreased in intial discharge, but increase in final discharge.

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Novel Cell-based Protease Assay System for Molecular Cell Biology and Drug Discovery

  • Hwang, Hyun-Jin;Kim, Jeong-Hee;Park, Joon-Woo;Kim, Sung-Hee;Lee, Min-Jeon;Jeong, Han-Seung;Hwang, In-Hwan
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.169.1-169.1
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    • 2003
  • Recently development of cell-based assay systems which are useful in molecular cell biology and drug discovery attracts significant attention. Here, we introduce a new technologies for monitoring enzyme activity and its inhibition inside living cells. Among various enzymes, proteases are important targets for studying various biological and disease-related processes such as viral infections, apoptosis and Alzheimer's disease. In this study, a sensitive cell-based protease detection system that enables direct fluorescence detection of a target protease and its inhibition inside living cells is introduced. (omitted)

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Analytical comparison of structural changes of plastic cell-based therapeutic drug storage containers when exposed to cryogenic environments (플라스틱 세포치료제 보관용기의 극저온 환경 노출 시 구조적 변화에 대한 해석적 비교)

  • Park, Jeong-Yeon;Lee, Dong-Mok;Lee, Jienny;Lee, Sun-ray;Yoon, Gil-Sang
    • Design & Manufacturing
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    • v.14 no.2
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    • pp.1-6
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    • 2020
  • Recently, research and commercialization related to the field of cell-based therapeutic drug development has been actively conducted. In order to maintain cell viability and prevent contamination, refrigeration preservation devices, such as CRF (controlled rate freezer) or vapor type LN2 tanks have been developed. On the other hand, the storage container for liquid nitrogen tanks currently on sale minimizes the flow structure to prevent structural defects when stored in a liquid nitrogen tank having a high thermal conductivity than vapor nitrogen. If the cell-based treatment drug is stored in the gaseous LN2 tank as it is, the cell survival after thawing is greatly reduced. It was estimated that the existing storage container structure was a factor that prevented the rapid entry and circulation of gaseous nitrogen into the container. Therefore, this study intends to propose a new supercellular storage container model that can maintain the mechanical strength while maximizing the fluid flow structure. To this end, we estimated that the structural change of the storage container effects on the equivalent stress formed around the through-holes of them when exposed to a cryogenic environment using thermal-structural coupled field analysis. As a result of storage experiments in the gas phase tank of the cell-based therapeutic agent using the developed storage container, it was confirmed that the cell growth rate was improved from 66% to 77%, which satisfied the transportation standards of the FDA(Food and Drug Administration) cell-based therapeutic agent.

A study on the measurement method of raw laver weight using load cell (로드셀을 이용한 생김 중량측정 방법에 관한 연구)

  • Eun-Bi MIN;Tae-Jong KANG;Eun-A YOON;Ok-Sam KIM;Doo-Jin HWANG
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.59 no.3
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    • pp.215-220
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    • 2023
  • This study developed and evaluated a load cell-based automatic weighing system for the automated harvesting of laver (Porphyra tenera) in seaweed aquaculture. The current manual harvesting process was compared with the load cell-based automated system, and quantitative measurements of time, distance, and weight were conducted. The results demonstrated that the load cell-based system reduced the unloading time and increased the throughput compared to the manual method. In addition, statistical analysis confirmed that there was no significant difference from the mean in the weight measurement obtained using the load cell-based system. Based on these findings, the load cell-based automatic weighing system holds potential for efficient production and transactions in laver cultivation, contributing to cost reduction and improving the quality of life for aquaculture workers.

Minimization of Cell-based Handoff Delays to Balance the Load in Fiber Optic Micro-cellular Systems (광마이크로셀 이동통신 시스템의 균등부하를 위한 셀단위 핸드오프 순서결정)

  • 이채영;장세헌
    • Journal of the Korean Operations Research and Management Science Society
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    • v.26 no.2
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    • pp.1-11
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    • 2001
  • This paper considers the scheduling of cell-based handoffs to balance the traffic in a fiber-optic microcelluar system. In the system depending on the order of cell based handoff, periodical balancing of the traffic among microcells can be achieved. The cell based handoff problem is formulated as a dynamic programming and the computational complexity is analyzed. Since the scheduling problem requires real time solution, heuristic algorithms are proposed and the computational results are discussed.

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