• Title/Summary/Keyword: Cell imaging

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Brain Magnetic Resolution Imaging to Diagnose Bing-Neel Syndrome

  • Kim, Ho-Jung;Suh, Sang-Il;Kim, Joo-Han;Kim, Byung-Jo
    • Journal of Korean Neurosurgical Society
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    • v.46 no.6
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    • pp.588-591
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    • 2009
  • Radiologic findings of Bing-Neel syndrome, which is an extremely uncommon complication resulting from malignant lymphocyte infiltration into the central nervous system (CNS) in patients with Waldenstr$\ddot{o}$m's macroglobulinemia (WM), have been infrequently reported due to extreme rarity of the case. A 75-year-old man with WM presented at a neurology clinic with progressive gait and memory disturbances, and dysarthria of 2 months duration. Cerebrospinal fluid and serum protein electrophoresis and immunofixation electrophoresis showed IgM kappa-type monoclonal gammopathy. Brain magnetic resonance imaging revealed multifocal, hyperintense lesions on T2 weighted-images. Brain diffusion-weighted imaging (DWI) demonstrated hyperintensities in cerebral and cerebellar lesions that appeared isointense on apparent diffusion coefficient maps, which were compatible with vasogenic edema. Although histologic analysis is a confirmative study to prove direct cell infiltration into the brain, brain MRI with DWI may be a good supportive study to diagnose Bing-Neel syndrome.

A Performance Evaluation of a Heat Dissipation Design for a Lithium-Ion Energy Storage System Using Infrared Thermal Imaging (적외선 열화상을 활용한 리튬 이온 ESS의 방열설계 성능평가에 관한 연구)

  • Kim, Eun-Ji;Lee, Gyung-Il;Kim, Jae-Yeol
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.19 no.5
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    • pp.105-110
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    • 2020
  • The global battery market is rapidly growing due to the development of vehicles(EV) and wireless electronic products. In particular logistics robots, which hielp to produce EVs, have attracted much interest in research in Korea Because logistics sites and factories operate continuously for 24 hours, the technology that can dramatically increase the operation time of the logistics equipment is rapidly developing, and various high-level technologies are required for the batteries used in. for example, logistics robots. These required technologies include those that enable rapid battery charging as well wireless charging to charge batteries while moving. The development of these technologies, however, result in increasing explosions and topical accidents involving rapid charging batteries These accidents due to the thermal shock caused by the heat generated during the charging of the battery cell. In this study, a performance evaluation of a heat dissipation design using infrared thermal imaging was performed on an energy storage systrm(Ess) applied with an internal heat conduction cooling method using a heating plate.

A Comparison of System Performances Between Rectangular and Polar Exponential Grid Imaging System (POLAR EXPONENTIAL GRID와 장방형격자 영상시스템의 영상분해도 및 영상처리능력 비교)

  • Jae Kwon Eem
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.31B no.2
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    • pp.69-79
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    • 1994
  • The conventional machine vision system which has uniform rectangular grid requires tremendous amount of computation for processing and analysing an image especially in 2-D image transfermations such as scaling, rotation and 3-D reconvery problem typical in robot application environment. In this study, the imaging system with nonuiformly distributed image sensors simulating human visual system, referred to as Ploar Exponential Grid(PEG), is compared with the existing conventional uniform rectangular grid system in terms of image resolution and computational complexity. By mimicking the geometric structure of the PEG sensor cell, we obtained PEG-like images using computer simulation. With the images obtained from the simulation, image resolution of the two systems are compared and some basic image processing tasks such as image scaling and rotation are implemented based on the PEG sensor system to examine its performance. Furthermore Fourier transform of PEG image is described and implemented in image analysis point of view. Also, the range and heading-angle measurement errors usually encountered in 3-D coordinates recovery with stereo camera system are claculated based on the PEG sensor system and compared with those obtained from the uniform rectangular grid system. In fact, the PEC imaging system not only reduces the computational requirements but also has scale and rotational invariance property in Fourier spectrum. Hence the PEG system has more suitable image coordinate system for image scaling, rotation, and image recognition problem. The range and heading-angle measurement errors with PEG system are less than those of uniform rectangular rectangular grid system in practical measurement range.

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Analysis of the Bird-cage Receiver Coil of a MRI System Employing a Equivalent Circuit Model Based on a Transmission Matrix (전송행렬 기반 등가 회로 모델을 이용한 자기공명영상 장치용 새장형 수신 코일 해석)

  • Kim, Hyun Deok
    • Journal of Korea Multimedia Society
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    • v.20 no.7
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    • pp.1024-1029
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    • 2017
  • A novel analytic solution has been derived for the bird-cage receiver coil of a magnetic resonance imaging (MRI) system, which is widely used in 3-dimensional medical imaging, by transforming the coil into an equivalent circuit model by using a transmission matrix-based circuit analysis. The bird-cage coil composed of N legs is divided into a cell for which input impedance is to be analyzed and the remaining N-1 cells, and then a transmission matrix corresponding to the N-1 cells is converted into a circuit to transform the 3-dimensional bird-cage coil into the 2-dimensional equivalent circuit model, which is suitable to derive the analytic solution for the input impedance. The proposed method derives directly the analytic solution for the input impedance at an arbitrary point of the coil unlike the conventional analytic solution of a bird-cage coil, so that it can be used not only for resonance frequency calculations but also for various coil characteristics analyses. Since the analytic solution agreed well with the results of computational simulations, it can be useful for the impedance matching of a coil and the analysis and the design of a multi-tune bird-cage coil.

Digital Infrared Thermal Imaging of Crape Myrtle Leaves Infested with Sooty Mold

  • Kim, Jiyeon;Kweon, Si-Gyun;Park, Junhyung;Lee, Harim;Kim, Ki Woo
    • The Plant Pathology Journal
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    • v.32 no.6
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    • pp.563-569
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    • 2016
  • The spatial patterns for temperature distribution on crape myrtle leaves infested with sooty mold were investigated using a digital infrared thermal imaging camera. The mean temperatures of the control and sooty regions were $26.98^{\circ}C$ and $28.44^{\circ}C$, respectively. In the thermal images, the sooty regions appeared as distinct spots, indicating that the temperatures in these areas were higher than those in the control regions on the same leaves. This suggests that the sooty regions became warmer than their control regions on the adaxial leaf surface. Neither epidermal penetration nor cell wall dissolution by the fungus was observed on the adaxial leaf surface. It is likely that the high temperature of black leaves have an increased cooling load. To our knowledge, this is the first report on elevated temperatures in sooty regions, and the results show spatial heterogeneity in temperature distribution across the leaf surface.

Synthesis of 18F Labelled Isoquinoline Salt for PET Imaging (PET 영상용 18F 표지 Isoquinolinium Salt의 합성)

  • Kim, Hee Jung;Kim, Dong Yeon;Kim, In Jong;Park, Jeong Hoon;Lee, Heung Nae;Kim, Sang Wook;Hur, Min Goo;Choi, Sang Moo;Yang, Seung Dae;Yu, Kook Hyun
    • Journal of Radiation Industry
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    • v.4 no.1
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    • pp.1-6
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    • 2010
  • The purpose of this study is to synthesize the radio fluorine labelled isoquinoline salt derivative as new radiopharmaceutical for imaging tumors using positron emission tomography (PET). The planarity of isoquinoline allows to inhibit topoisomerase or intercalate between adjacent DNA base pairs, which result in producing double strand breaks in the DNA and a cell death. Therefore, the isoquinoline has seemed to have a potential anticancer activity. In order to obtain 2-(5-[$^{18}F$]fluoropentylisoquinolinium salt with good radiochemical yield, tosylated precursors have been synthesized. The labelling reaction was carried out for 30 minute in HMPA at $120^{\circ}C$. The radiochemical yield was about 50~60%.

FAP Inhibitors as Novel Small Molecules for Cancer Imaging using Radionuclide

  • Anvar Mirzaei;Jung-Joon Min;Dong-Yeon Kim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.9 no.1
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    • pp.49-55
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    • 2023
  • Tumors are encircled by various non-cancerous cell types in the extracellular matrix, including fibroblasts, endothelial cells, immune cells, and cytokines. Fibroblasts are the most critical cells in the tumor stroma and play an important role in tumor development, which has been highlighted in some epithelial cancers. Many studies have shown a tight connection between cancerous cells and fibroblasts in the last decade. Regulatory factors secreted into the tumor environment by special fibroblast cells, cancer-associated fibroblasts (CAFs), play an important role in tumor and vessel development, metastasis, and therapy resistance. This review addresses the development of FAP inhibitors, emphasizing the first, second, and latest generations. First-generation inhibitors exhibit low selectivity and chemical stability, encouraging researchers to develop new scaffolds based on preclinical and clinical data. Second-generation enzymes such as UAMC-1110 demonstrated enhanced FAP binding and better selectivity. Targeted treatment and diagnostic imaging have become possible by further developing radionuclide-labeled fibroblast activation protein inhibitors (FAPIs). Although all three FAPIs (01, 02, and 04) showed excellent preclinical and clinical findings. The final optimization of these FAPI scaffolds resulted in FAPI-46 with the highest tumor-to-background ratio and better binding affinity.

Intracranial Plasma Cell Granuloma - A Case Report - (두개강 내에서 발견된 형질 세포 육아종 - 증례보고 -)

  • Lyo, In Uk;Suh, Jae Hee;Kwon, Yang
    • Journal of Korean Neurosurgical Society
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    • v.30 no.6
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    • pp.774-776
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    • 2001
  • We report a 35-year old female patient with history of seizure and mass which was confirmed as a plasma cell granuloma, arising in the left parietal area. The mass appeared on magnetic resonance imaging as well circumscribed area of decreased signal that markedly enhanced with administration of the contrast. Pathologically, biopsy showed a mixed cellular population with considerable numbers of plasma cells along with eosinophils and lymphocytes and the tumors was characterized immunohistochemically by polyclonal population of lymphoid cells.

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Radiographic features of plasma cell leukemia in the maxilla: A case report

  • Wong, Phillip;Kashtwari, Deeba;Nair, Madhu K.
    • Imaging Science in Dentistry
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    • v.46 no.4
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    • pp.273-278
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    • 2016
  • Plasma cell leukemia (PCL) is an aggressive form of multiple myeloma where there is hematogenous spread of abnormal plasma cells into the periphery. This is opposed to multiple myeloma, where the abnormal plasma cells stay in the bone marrow. PCL is more common in males than females, and is also more common in African-Americans than Caucasians. Signs and symptoms of PCL include, but are not limited to, renal insufficiency, hypercalcemia, anemia, lytic bone lesions, thrombocytopenia, hepatomegaly, and splenomegaly. Here, we discussed a case of a 71-year-old Caucasian female recently diagnosed with primary PCL with radiographic features of this disease throughout the body, with an emphasis on the maxillofacial skeleton and relevance from a dental standpoint.

Akashiwo sanguinea (Dinophyceae) extruding mucous from pores on the cell surface

  • Badylak, Susan;Phlips, Edward J.;Mathews, A. Loren;Kelley, Karen
    • ALGAE
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    • v.29 no.3
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    • pp.197-201
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    • 2014
  • This is the first recorded observation of Akashiwo sanguinea excreting mucilaginous substances from pores on the cell surface. Observations were from samples collected in the Caloosahatchee Estuary, Florida, USA during a bloom event, with densities of 672 cells $mL^{-1}$ of A. sanguinea, including 51 cells surrounded by mucous. Scanning electron microscopy observations revealed that the mucous was secreted from thecal pores on the cell surface. The potential significance of mucous production is discussed.