• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.52.1-52.1
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• 2011

In this work, the effect of the addition of bioactive glass in the biocompatibility and mechanical behavior of conventional TTCP/DCPA based bone cement were investigated. The cement was initially modified with chitosan and HPMC which cross-linked with citric acid to improved mechanical properties.The injectable bone substitutes were further modified by adding varying amounts of bioactive glass (0%, 10%, 20% and 30%) and its effects on the biocompatibility of the material were studied. Afterbio-glass powders were mixed with the optimized composition for HPMC and citric acid content,the IBS was incubated at $37^{\circ}C$ at different time intervals and showed progressive formation of HAp with increasing time. Mechanical properties like Vickers hardness and compressive strength were found to increase with the increasing amount of bioactive glass addition and that setting time was shortened. The fabricated IBS morphologies were further characterized using SEM. MTT assay was performed to check the cell cytotoxicity and cell proliferation for 1, 3 and 5 days. Cell morphology, adhesion and proliferation behavior of cell in the IBS by culturing MG-63 cells on the IBS for 20, 60 and 90 mins and 1, 3 and 5 days was also investigated. All the results showed increasing biocompatibility as the bioglass content increased. MTT results found the materials to be cytocompatible and SEM images showed that cells attached and proliferated successfully.

• Journal of muscle and joint health
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• v.27 no.2
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• pp.153-159
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• 2020

Purpose: This study aims to identify the effect of university students' intention to donate hematopoietic stem cells based on the theory of planned behavior. Methods: The subjects include university students who visited the campaign for the registration of hematopoietic stem cell donation held at H university on September 28, 2019 and October 2, 2019. Results: The intention to register for hematopoietic stem cell donation and empirical attitude (r=.72, p<.001), instrumental attitude (r=.64, p<.001), directive norm (r=.53, p<.001), technical norms (r=.55, p<.001) and self-efficacy (r=.86, p<.001) showed a significant positive correlation. The multiple regression analysis revealed that self-efficacy (β=.66) and empirical attitude (β=.23) were the most influential factors. Conclusion: Educational and promotional programs to increase the intention to register for hematopoietic stem cell donation need to be developed to help increase students' self-efficacy and help them develop a positive experiential attitude. In addition, further research is needed to determine whether the intention to register in hematopoietic stem cell donation among university students can lead to actual registration and donation after registration.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.15 no.3
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• pp.179-184
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• 1982

The behavior of continuous flow culture of Lartobacillus bulgricus was investigated by application of Monod's kinetic model. The parameters obtained from Monod's chemostat theory successfully predicted the behavior of the chemostat. Then, it was found that Monod's kinetics were applicable to the growth rate dependence on glucose concentration. Under steady-state condition, the maximum growth rate, saturation constant, and wash out were found to be 0.62/hr, 7.69 g/1, 0.51/hr of continuous culture. And the optimum condition for the highest cell production was 0.41/hr in dilution rate, and at that point the cell production rate was 0.178g/1 hr.

• Journal of Power Electronics
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• v.13 no.1
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• pp.122-138
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• 2013

Adaptive control of a peak current mode controlled (PCM) boost converter supplied by a PEM fuel cell is described in this paper. The adaptive controller with reference model and signal adaptation is developed in order to compensate the deviation of the response during the change of the operating point. The procedure for determining the adaptive algorithm's weighting coefficients, based on a combination of the pole-zero placement method and an optimization method is proposed. After applying the proposed procedure, the optimal adaptive algorithm's weighting coefficients can be determined in just a few iterations, without the use of a computer, thus greatly facilitating the application of the algorithm in real systems. Simulation and experimental results show that the dynamic behavior of a highly nonlinear control system with a fuel cell and a PCM boost converter, can fairly accurately be described by the dynamic behavior of the reference model, i.e., a linear system with constant parameters.

• Journal of Hydrogen and New Energy
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• v.25 no.4
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• pp.386-392
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• 2014

The effective water management in a polymer electrolyte membrane fuel cell (PEMFC) is one of the key strategies for improving cell performance and durability. In this work, an ex situ measurement was carried out to understand the water droplet behavior on the surface of gas diffusion layer (GDL) as a fundamental study for establishing novel water management. For that purpose, simplified cell including one rib and two flow channels was designed and fabricated. Using this ex situ device, the water droplet emergence through the GDL of the PEMFC was emulated to understand liquid water transport through the porous diffusion medium. Through the visualization experiment, the emergence and growth of water droplets at the channel/GDL interface are mainly observed with the surface characteristics of GDL (SGL 10BA, 24BA) and rib when the liquid water passes through the GDL and is expelled to the flow channel. It is expected that the results obtained from this study can contribute to the better understanding on the water droplet behavior (emergence and removal) in the flow channels of PEMFC.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.7
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• pp.785-792
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• 2012

Foam structure is usually hard to model due to the complexity of the geometry of cells. So, many simplified models to represent complicated foam structures have been proposed, but most of them are not actually describe the random feature of the cell structure well. So, in this study, two dimensional isotropic and anisotropic closed cell structures of the foam were modeled using the concept of Voronoi cells. The elasto-plastic deformation behavior under compressive loads was investigated by finitie element analysis, and the results were compared with ideal honeycomb structure. In addition, the effect of anisotropy of Voronoi cell structures of the foam on Young's modulus and yield stress under compressive loads was studied.

• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.80-80
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• 2003

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by marked cell death in the striatum and cortex. Stereotaxic injection of quinolinic acid (QA) into striatum results in a degeneration of GABAergic neurons and exhibits abnormal motor behaviors typical of the illness. The objective of this study was carried out to obtain basic information about whether parthenogenetic mouse embryonic stem (PmES) cells are suitable for cell replacement therapy of HD. To establish PmES cell lines, hybrid F1 (C57BL/6xCBA/N) mouse oocytes were treated with 7% ethanol for 5 min and cytochalasin-B for 4 hr to initiate spontaneous cleavage. Thus established PmES cells were induced to differentiate using bFGF (20ng/ml) followed by selection of neuronal precursor cells for 8 days in N2 medium. After selection, cells were expanded at the presence of bFGF (20 ng/ml) for another 6 days, then a final differentiation step in N2 medium for 7 days. To establish recipient animal models of HD, young adult mice (7 weeks age ICR mice) were lesioned unilaterally with a stereotaxic injection of QA (60 nM) into the striatum and the rotational behavior of the animals was tested using apomorphine (0.1mg/kg, IP) 7 days after the induction of lesion. Animals rotating more than 120 turns per hour were selected and the differentiated PmES cells (1$\times$10$^4$cells/ul) were implanted into striatum. Four weeks after the graft, immunohistochemical studies revealed the presence of cells reactive to anti-NeuN antibody. However, only a slight improvement of motor behavior was observed. By Nissl staining, cell mass resembling tumor was found at the graft site and near cortex which may explain the slight behavioral improvement. Detailed experiment on cell viability, differentiation and migration explanted in vivo is currently being studied.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.890-893
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• 2002

This study is focused to predict the behavior of Al foam with closed-cell structure during the 3 point bending test and the upsetting test according to aspect ratio. We calculated characters of aluminum foams with closed-cell structure and took the simulation. The effects on the aspect ratio of the cell was investigated parametrically. The analysis was carried out on two models, First, the bending test in elasticity of the rectangular beam, and Second, the upsetting test in plasticity of the circular cylinder. In the analysis, the deformation of the beam and the cylinder was influenced by the aspect ratio of the cell. Further, We assumed that the geometry of feared aluminum cell change the stress and strain in the test.

• Journal of the Korean Ceramic Society
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• v.34 no.11
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• pp.1139-1150
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• 1997

A model for predicting the relative density and the compressive strength of open-cell ceramics with three-dimensional network structure was proposed through the interpretation of their macrostructure and fracture mechanics. The equation predicting the relative density was derived under the assumption that the open-cell structure was a periodic array of the tetrakaidecahedron unit cell consisting of cylindrical struts containing the internal hollow with the shape of a triangular prism. The model for compressive strength of open-cell ceramics with the hollow strut was also developed by modifying conventional model which based on fracture behavior of them subjected to the compressive stress. Both the relative density and the compressive strength were expressed in terms of the ratio of the strut diameter to the length together with the ratio of the hollow size to the strut diameter. The proposed model for the relative density and the compressive strength of the alumina-zirconia composite with open-cell structure were accorded well with the experimental values, whereas Gibson-Ashby and Zhang's model did not show such a good agreement.

• Journal of the Korea Society for Simulation
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• v.8 no.4
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• pp.1-8
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• 1999

This paper proposes an ATM switch architecture called Output Queued Batcher-Banyan switch (OQBBS). It consists of a Sorting Module, Expanding Module, and Output Queueing Modules. The principles of channel grouping and output queueing are used to increase the maximum throughput of an ATM switch. One distinctive feature of the OQBBS is that multiple cells can be simultaneously delivered to their desired output. The switch architecture is shown to be modular and easily expandable. The performance of the OQBBS in terms of throughput, cell delays, and cell loss rate under uniform random traffic condition is evaluated by computer simulation. The throughput and the average cell delay are close to the ideal performance behavior of a fully connected output queued crossbar switch. It is also shown that the OQBBS meets the cell loss probability requirement of $10^{-6}$.