• 제목/요약/키워드: Causal knowledge

검색결과 307건 처리시간 0.029초

First Report of Cucumber mosaic virus Infecting Pinewood Coneflower (Rudbeckia bicolor) in Korea

  • Kim, Mi-Kyeong;Kwak, Hae-Ryun;Ko, Sug-Ju;Lee, Su-Heon;Kim, Jeong-Soo;Kim, Kook-Hyung;Cha, Byeong-Jin;Choi, Hong-Soo
    • The Plant Pathology Journal
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    • 제26권1호
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    • pp.93-98
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    • 2010
  • A virus isolate causing symptoms of yellow mosaic, fern leaves, malformation and plant necrosis on Rudbeckia bicolor was prevalent around Pyeongchang area in Korea. The causal virus was identified as Cucumber mosaic virus (CMV) using characteristics from biological, serological and molecular analyses and named as CMV-Rb. CMV-Rb caused mosaic on Nicotiana benthamiana, N. tabacum, Capsicum annuum, and Lycopersicon esculentum. However, typical local lesions did not develop on inoculated Pisum sativum, Cucurbita moschata, Datura stramonium and Tetragonia expansa plants. Full-length genome sequences of CMV-Rb RNAs 1, 2 and 3 were obtained using 12 primer pairs by RT-PCR analysis. The genome of CMV-Rb RNA segments 1, 2, and 3 consists of 3363nt, 3049nt, and 2214nt in length, respectively. In order to ascertain their taxonomic identity, nucleotide and the deduced amino acid sequence analyses RNAs 1, 2 and 3 of CMV-Rb isolates were conducted with previously reported sequences of CMV strains and/or isolates. CMV-Rb RNAs showed about 90 to 99% sequence identity to those of subgroup I strains suggesting that CMV-Rb is more closely related to CMV isolates belong to subgroup I. To our knowledge, this is the first report of CMV on Rudbeckia bicolor in Korea.

국내에서 보고된 한약 및 민간요법, 건강식품 관련 약인성간손상에 대한 체계적 고찰 (Hepatotoxic Events Associated with Herbal Medicinal Products, Folk Remedies and Food Supplements in Korea)

  • 박해모;장인수;이선동
    • 대한한의학회지
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    • 제26권2호
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    • pp.152-165
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    • 2005
  • Background: The use of herbal preparations as remedies for various medical conditions has continuously increased in Korea Large proportions of Korean patients use herbal medicinal products, folk remedies, and food supplements. However, studies on the safety of herbal products arc conducted on a less than sufficient basis even in the countries like Korea where herbal medicine is being used extensively. Some of the reports on the safety of herbs were done by the doctors of western medicine but lack of knowledge and misclassification led to misunderstandings. Objecitves: This study aims to review the recent evidences on hepatotoxic events associated with the use of herbal medicinal products, folk remedy, and food supplements. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. Methods: Systematic literature searches were performed on MedRic and MEDLIS in Korea. Screening and selection of the articles and the extraction of data were performed independently by two of authors. There were no restrictions regarding the published date. In order to avoid bias, the articles written by medical doctors, not by oriental doctors were selected. 43 journals were chosen for the review. Results: Analyzing the number of journals, studies on the drug-induced liver injury were increased after the year 2000. The proportion of herbal and folk remedy associated hepatotoxic injuries in all drug-induced liver injury was $21.0\%-30.0\%$. But criterion for herbal medicine is rather vague and limited objective data hindered objectiveness. Few of single medicinal herbs and combination preparations were associated with hepatotoxic injuries. But because of lack of objectivity, further researches must be conducted to yield more concrete results. Conclusions: yield more concrete results. Incidence figures are largely unknown, and in most cases a causal attribution is not established. The challenge for the future is to systematically research this area, educate all parties involved, and minimize patient risks.

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First Report of Potato Stem-End Rot Caused by Fusarium oxysporum in Korea

  • Aktaruzzaman, Md.;Xu, Sheng-Jun;Kim, Joon-Young;Woo, Jae-Hyoun;Hahm, Young-Il;Kim, Byung-Sup
    • Mycobiology
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    • 제42권2호
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    • pp.206-209
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    • 2014
  • In this study, we identified the causative agent of stem-end rot in potatoes that were grown in Gangwon alpine areas of Korea in 2013. The disease symptoms included appearance of slightly sunken circular lesion with corky rot on the potato surface at the stem-end portion. The fungal species isolated from the infected potatoes were grown on potato dextrose agar and produced white aerial mycelia with dark violet pigments. The conidiophores were branched and monophialidic. The microconidia had ellipsoidal to cylindrical shapes and ranged from $2.6{\sim}11.4{\times}1.9{\sim}3.5{\mu}m$ in size. The macroconidia ranged from $12.7{\sim}24.7{\times}2.7{\sim}3.6{\mu}m$ in size and had slightly curved or fusiform shape with 2 to 5 septate. Chlamydospores ranged from $6.1{\sim}8.1{\times}5.7{\sim}8.3{\mu}m$ in size and were present singly or in pairs. The causal agent of potato stem-end rot was identified as Fusarium oxysporum by morphological characterization and by sequencing the internal transcribed spacer (ITS1 and ITS4) regions of rRNA. Artificial inoculation of the pathogen resulted in development of disease symptoms and the re-isolated pathogen showed characteristics of F. oxysporum. To the best of our knowledge, this is the first study to report that potato stem-end rot is caused by F. oxysporum in Korea.

자가간호에 관한 연구동향 및 명제분석 (An Analyses of Research Trend and Proposition Related to Self-care)

  • 강현숙;김원옥;현경선;조현숙;김정화;왕명자;백승남;원정숙;정연;석소현;이은미;장정미
    • 대한간호학회지
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    • 제28권4호
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    • pp.1013-1026
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    • 1998
  • This study was performed to analyse the tendency of the self-care studies, to investigate the variables related to self-care, which could be applied for the data establishing the theory of self-care. To accomplish the objectives of this study, the researchers analyzed 83 studies available that contained the area of self-care, which was published in local and foreign areas between 1981 and Feb. 1997. The findings of this study are as follows : 1) Studies published in Korea were about twice more than foreign studies. According to the statistics, the number of studies in this study tended to increase year by year. Between 1991 and 1995 were most. Analysis on the subject of those studies showed, that they were most dealt with chronic diseases an adaults. 2) The theoretical definition of self-care were most referred to Orem's self-care. For the main concept of studies, self care performance was the most. 3) The correlational study was most often used design and experimental study is tended to increase. The questionnares were the most often used data collection method. There was lots of different variable measuring technique to evaluate main concepts. 4) In the results of analysis on the propositions related to the self-care performance, a client's education, social support, self-efficacy, and level of knowledge as a causal variable were found. Also, the physiological index improved and quality of life were found to be significant effective variables.

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뇌 기반 진화적 접근법을 적용한 초등학교 학생의 과학 자유탐구에서 인지적 영역 분석 (Analyses on Elementary Students' Cognitive Domain in Free Science Inquiry Activities Applying a Brain-Based Evolutionary Approach)

  • 백자연;임채성;김재영
    • 한국초등과학교육학회지:초등과학교육
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    • 제33권4호
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    • pp.773-783
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    • 2014
  • In National Curriculum of Science revised in 2007, the Free Inquiry was newly introduced to increase students' interest in science and to foster creativity by having students make their own question and find answer by themselves. The purpose of the study was to analyze characteristics, in cognitive domain, appeared in the processes of performing the Free Inquiry activities applying a brain-based evolutionary science teaching and learning principles. For this study, 106 fifth grade students participated, and they performed individually Free Inquiry activities. In order to characterize of the diversifying, estimating-evaluating-executing, and extending-applying activities in cognitive domain (C-DEF), the Free Inquiry diary constructed by the students, observations by a researcher, and interviews with the students were analyzed both quantitatively and qualitatively. The major results of this study were as follows: First, at C-D step, many students (71.5%) had difficulty in searching the meanings of their results and the contents of interpretations were at the level of simple description of their results. A few students (15.2%) derived interpretations based on causal relationships between specific variable and result. Also, the tendency that the numbers of interpretation about meaning of their results were increased as the scores of science attitude and achievement was appeared. Second, at C-E step, the students showed tendency of considering facts exactly explaining inquiry topic and being appliable to daily life rather than objectivity or accuracy of scientific knowledge. Third, at C-F step, there were three types of extension and application: simple repetition (8.2%), extension (64.0%), and upward application (17.6%) types. Based on these findings, implications for supporting appropriate interpretation, evaluation, and application of inquiry results are discussed.

The Roles of Two hfq Genes in the Virulence and Stress Resistance of Burkholderia glumae

  • Kim, Jieun;Mannaa, Mohamed;Kim, Namgyu;Lee, Chaeyeong;Kim, Juyun;Park, Jungwook;Lee, Hyun-Hee;Seo, Young-Su
    • The Plant Pathology Journal
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    • 제34권5호
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    • pp.412-425
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    • 2018
  • The Hfq protein is a global small RNA chaperone that interacts with regulatory bacterial small RNAs (sRNA) and plays a role in the post-transcriptional regulation of gene expression. The roles of Hfq in the virulence and pathogenicity of several infectious bacteria have been reported. This study was conducted to elucidate the functions of two hfq genes in Burkholderia glumae, a causal agent of rice grain rot. Therefore, mutant strains of the rice-pathogenic B. glumae BGR1, targeting each of the two hfq genes, as well as the double defective mutant were constructed and tested for several phenotypic characteristics. Bacterial swarming motility, toxoflavin production, virulence in rice, siderophore production, sensitivity to $H_2O_2$, and lipase production assays were conducted to compare the mutant strains with the wild-type B. glumae BGR1 and complementation strains. The hfq1 gene showed more influence on bacterial motility and toxoflavin production than the hfq2 gene. Both genes were involved in the full virulence of B. glumae in rice plants. Other biochemical characteristics such as siderophore production and sensitivity to $H_2O_2$ induced oxidative stress were also found to be regulated by the hfq1 gene. However, lipase activity was shown to be unassociated with both tested genes. To the best of our knowledge, this is the first study to elucidate the functions of two hfq genes in B. glumae. Identification of virulence-related factors in B. glumae will facilitate the development of efficient control measures.

조직 구성원의 흡수능력, 조직 시민 행동, SCM 성과 및 혁신의도 간 연관관계 연구 (A Study on the Relationships Among Absorptive Capacity of Employees, Organizational Citizenship, SCM performance, and Intention to Innovate)

  • 김태웅;김경희;김재현
    • 인터넷정보학회논문지
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    • 제13권5호
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    • pp.65-75
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    • 2012
  • 조직시민행동이란 조직내의 공식적 역할이나 기능을 넘어서는 구성원들의 재량적 행동을 의미하며, 조직의 성과 제고에 상당한 기여를 하는 것으로 알려져 있다. 공급망관리(SCM) 시스템이 도입되면, 글로벌 표준, 프로세스 혁신, 핵심성과지표 등에 관한 정보가 여러 부서에 폭넓게 전달되어 구성원들의 흡수 및 혁신능력을 제고할 수 있다. 구성원들의 조직시민행동은 이런 과정을 활성화시켜 SCM 성과를 증진시키며 결과적으로 조직 혁신에 기여할 수 있다. 본 논문은 국내에서 비즈니스를 전개하고 있는 글로벌 제조 기업에 근무하고 있는 조직구성원의 흡수능력과 조직시민행동의식, SCM의 성과 및 혁신의도 간 인과관계 분석에 초점을 둔다. 122명으로부터 수집한 설문자료를 통계적으로 분석한 결과, 조직시민행동은 SCM 성과와 흡수능력에 긍정적 영향을 미치며, 흡수능력 또한 SCM 성과에 직접적 영향을 미치는 것으로 나타났다. 기대한 바와 같이 SCM 성과는 혁신의도의 유의한 선행요인으로 분석되었지만, 조직구성원의 흡수능력은 별다른 영향을 미치지 못하는 것으로 나타났다. 그 외 본 연구결과의 학술적, 실무적 시사점도 함께 제시하였다.

달 크레이터 생성에 대한 대학생들의 정신모형 분석 (An Analysis of Undergraduate Students' Mental Models on the Mechanism of the Moon Craters Formation)

  • 이호;조현준;이효녕
    • 한국지구과학회지
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    • 제28권6호
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    • pp.655-672
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    • 2007
  • 이 연구의 목적은 천문학을 전공하지 않은 대학생들의 달 크레이터 생성에 대한 정신모형 형성과정에 활용되는 정보 출처의 종류와 추론의 유형을 알아보는데 있다. 연구 목적을 달성하기 위해, 개별 심층 면담 방법이 설계되었으며, 면담 내용은 분석적 귀납에 의해 생성되었다. 면담은 4명의 대학생들과 개별적으로 이뤄졌으며, 면담 과정은 Seidman의 단계를 따랐다. 연구 결과, 이들은 달 크레이터 생성에 관하여 비과학적이긴 하지만 일관성 있는 설명체계를 형성하고 있었다. 이들은 대체로 운석 충돌에 의해 구덩이가 생성된다고 설명하였으며, 생성된 크레이터의 모양과 관련된 변인으로는 개인마다 차이가 있었으나 운석의 모양을 공통적으로 제시하였다. 이들의 설명체계에 활용된 정보원으로는 일상에서의 경험과 교과지식, 직관이 활용되고 있었고, 인과적 추론, 직관적 추론, 지식기반추론, 비유적 추론을 활용하고 있었다.

매체 풍요도, 사회적 존재감 및 생활 만족도가 상대적 박탈감을 통해 SNS 이용자의 이용 지속 의도 또는 이탈 의도에 미치는 영향 (The Effect of Media Richness, Social Presence, and Life Satisfaction on Continuance Usage Intention or Withdrawal Intention of SNS Users via Relative Deprivation)

  • 이은곤
    • 유통과학연구
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    • 제14권10호
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    • pp.165-178
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    • 2016
  • Purpose - This study aims to empirically verify the impact of media richness, social presence, and prior life satisfaction on various continual usage or withdrawal behaviors of SNS users via both a positive path of satisfaction and a negative path of relative deprivation. By identifying these causal paths, we observe dynamic interactions of SNS user psychology in a balanced view, and provide some implications about design principles for SNS providers. Research design, data, and methodology - We developed 16 hypothesis based on media richness theory, social presence theory, social comparison theory, the literature about relative deprivation, and the literature about the various reactions of IS users. The rich SNS media, social presence recognition among peer SNS users, and prior life satisfaction could generate positive experience, attitude, and virtuous behavioral intentions among SNS users. At the same time, rich media, low social presence, and low prior life satisfaction could generate relative deprivation and could increase withdrawal behavioral intentions such as refusal to provide information, misrepresentation of information, and removal of uploaded information in SNS. Scenario surveys were conducted to collect data from potential SNS users. Data from 357 surveys were collected and analyzed through a PLS algorithm to test the hypotheses. Results - Media richness, social presence, and prior life satisfaction could significantly increase perceived enjoyment, satisfaction, and behavioral intention of continual usage and knowledge sharing. They also could significantly decrease refusal and misrepresentation intention. Relative deprivation is significantly decreased only by prior life satisfaction. Relative deprivation could not significantly decrease satisfaction, but it could significantly increase misrepresentation and removal intention, which could be regarded as information distortion intention. Conclusions - SNS providers should focus on developing rich media and social presence support because these two variables could impact the positive experiences of SNS users. Moreover, the positive experiences could heavily influence SNS user behavior. Some management is needed to prevent relative deprivation and its consequences of misrepresentation and removal intention. SNS providers should prevent SNS users from excessive image misrepresentation and removal as this information distortion could be the source of relative deprivation.

건설 근로자의 개인특성 및 안전행동 간의 경로모형 구축 (Developing the Path Model defining the Relationship between Construction Worker's Personal Characteristics and Safety Behaviors)

  • 진형성;이동은
    • 한국건축시공학회지
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    • 제13권2호
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    • pp.169-180
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    • 2013
  • 본 논문은 건설현장에서 사고의 주체인 근로자의 개인적 특성과 안전행동에 대한 인과관계 규명 및 직 간접적인 영향력을 분석하는 것에 목적이 있다. 이를 위해 선행연구를 통해 개인적 특성 관련 변인들을 선출하고 '개인적 특성-안전행동'에 대한 이론 모형을 구안하였다. 모형 검증을 위해 대구 경북 건설현장의 근로자 399명을 대상으로 설문조사를 실행하고, SPSS 18.0과 AMOS 18.0을 활용하여 탐색적 요인분석, 신뢰도분석, 구조분석을 실시하였다. 직 간접효과를 분석하기 위해 적합도 지수와 매개효과 검증을 실시하였다. 본 연구의 결과는 개인성격 중 '성실성'과 '개방성 및 외향성'이 안전행동에 직접적인 영향을 미치면서 동시에 '스트레스반응', '안전동기', '안전지식'을 매개로 안전행동에 간접적인 영향을 미친다는 것을 확인하였다.