• 제목/요약/키워드: Causal association

검색결과 978건 처리시간 0.026초

Chronic Infections of the Urinary Tract and Bladder Cancer Risk: a Systematic Review

  • Anderson-Otunu, Oghenetejiri;Akhtar, Saeed
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권8호
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    • pp.3805-3807
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    • 2016
  • Literature on the relationship between recurrent urinary tract infections and urinary bladder carcinoma risk has been inconsistent. Therefore, we carried out this systematic review of observational studies to ascertain if there is any association between chronic urinary tract infection and urinary bladder carcinoma. A total of 10 databases were searched using Boolean: CINAHL, PUBMED, Google Scholar, Medline, Science Direct, SCIRUS, Cochrane, UK PubMed central, NHS evidence and WHO-website. The search yielded an initial hit of 3,518 articles and after screening and critical appraisal, seven studies were included for this review. Four articles reported an association between chronic urinary tract infections and bladder cancer while three concluded a weak or no association at least in one gender. Main findings in this review were that most of the studies reported an association between chronic urinary tract infections and bladder cancer risk. However, inferences about the causal association between chronic urinary tract infections and bladder cancer risk should be drawn cautiously considering the methodological limitations of case-control studies included in this review. Therefore, more empirical evidence is needed to determine the causal nature of relationships between chronic urinary tract infections and bladder cancer risk.

시간 속성을 갖는 이벤트의 의미있는 희소 관계에 기반한 연관 규칙 탐사 (Finding Association Rules based on the Significant Rare Relation of Events with Time Attribute)

  • 한대영;김대인;김재인;송명진;황부현
    • 정보처리학회논문지D
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    • 제16D권5호
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    • pp.691-700
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    • 2009
  • 이벤트는 환자의 증상과 같이 시간 속성을 갖는 하나의 흐름을 의미하며 인터벌 이벤트는 시작과 종료 시점에 대한 시간 간격을 갖는다. 그리고 시간 데이터마이닝에 대한 많은 연구가 있었지만 환자 이력, 구매자 이력, 로그 이력과 같은 인터벌 이벤트에 대한 지식 탐사 방법에 대한 연구는 미흡하다. 이 논문에서는 이벤트들의 인과 관계에 대한 연관 규칙을 탐사하고 이 규칙에 기반하여 결과 이벤트 발생을 예측하는 시간 데이터마이닝 방법을 제안한다. 제안 방법은 이벤트 시간 속성을 사용하여 인터벌 이벤트로 요약하고 이벤트들의 인과 관계를 탐사하여 이벤트 발생을 예측한다. 성능평가를 통하여 제안 방법은 다양한 지지도를 적용하여 발생 빈도에 상관없이 이벤트 발생에 높은 영향을 주는 의미있는 희소 관계를 발견함으로써 기존의 데이터마이닝 기법에 비하여 보다 우수한 정보를 탐사할 수 있다.

Detection of QTL on Bovine X Chromosome by Exploiting Linkage Disequilibrium

  • Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • 제21권5호
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    • pp.617-623
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    • 2008
  • A fine-mapping method exploiting linkage disequilibrium was used to detect quantitative trait loci (QTL) on the X chromosome affecting milk production, body conformation and productivity traits. The pedigree comprised 22 paternal half-sib families of Black-and-White Holstein bulls in the Netherlands in a grand-daughter design for a total of 955 sons. Twenty-five microsatellite markers were genotyped to construct a linkage map on the chromosome X spanning 170 Haldane cM with an average inter-marker distance of 7.1 cM. A covariance matrix including elements about identical-by-descent probabilities between haplotypes regarding QTL allele effects was incorporated into the animal model, and a restricted maximum-likelihood method was applied for the presence of QTL using the LDVCM program. Significance thresholds were obtained by permuting haplotypes to phenotypes and by using a false discovery rate procedure. Seven QTL responsible for conformation types (teat length, rump width, rear leg set, angularity and fore udder attachment), behavior (temperament) and a mixture of production and health (durable prestation) were detected at the suggestive level. Some QTL affecting teat length, rump width, durable prestation and rear leg set had small numbers of haplotype clusters, which may indicate good classification of alleles for causal genes or markers that are tightly associated with the causal mutation. However, higher maker density is required to better refine the QTL position and to better characterize functionally distinct haplotypes which will provide information to find causal genes for the traits.

은퇴태도와 은퇴계획수준의 인과관계에 관한 연구 (Causal Effects on Attitude toward Retirement and the Level of Retirement Planning)

  • 홍성희;곽인숙
    • 가정과삶의질연구
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    • 제25권2호
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    • pp.89-104
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    • 2007
  • The purpose of this study was to analyze the affecting factors on male salary workers' level of retirement planning. The focus was on the causal effects on salary workers' attitude toward retirement and their level of retirement planning. The major findings were as follows.: First, the salary worker's attitude toward retirement was neutral, neither positive nor negative, and they estimated their level of retirement planning relatively high. Second, the major factors affecting on attitude toward retirement were salary workers' age, their current economic status, and future perspectives for the post-retirement life. Third, the major affecting factors on level of retirement planning were salary workers' age, health status, and level of self-esteem, household net asset, savings and investment for elderly life, and attitude toward retirement. forth, the causal effects on the level of retirement planning was verified, and attitude toward retirement had direct effect as well as indirect effect on the level of retirement planning. From the findings, it can be concluded that the salary workers' attitude toward retirement played a important role in the process of retirement planning.

Strategic Intuition Capability toward Performance of Entrepreneurs: Evidence from Thailand

  • AUJIRAPONGPAN, Somnuk;RU-ZHE, Jintanee;JUTIDHARABONGSE, Jaturon
    • The Journal of Asian Finance, Economics and Business
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    • 제7권6호
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    • pp.465-473
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    • 2020
  • The objective of this research is to study the confirmative components of strategic intuition capability and the study of causal influence between strategic intuition capability and firm performance of SMEs in Thailand. The consistency method, structural equation models and empirical data were used to test the influential factors on firm performance. Models were then proposed for the development of the strategic intuition capability of entrepreneurs in Thailand. The research sample consisted of 342 SME provincial champion entrepreneurs listed with Thailand's Office of Small and Medium Enterprises. The research results reveal that the model of strategic intuition capability responded well to the empirical data. Additionally, a relationship was identified between firm performance and the causal influence of the strategic intuition capability of entrepreneurs. In accordance with the empirical data, the strategic intuition capability of entrepreneurs had a significant causal influence on firm performance (Chi-square = 35.71, df = 25, P-value = 0.07615, GFI = 0.98, AGFI = 0.96, RMSEA = 0.033, RMR = 0.027). Furthermore, with respect to the development of strategic intuition capability, the development of genuine wisdom based on systematic knowledge management achieved via conscious mental concentration may lead to the next stage of strategic intuition.

육류에 대한 쾌락적 신념, 양면가치, 주관적 규범, 태도와 육류 소비행동의 인과관계 평가 (Assessing the Causal Relationships among Hedonic belief, Ambivalence, Subjective norm, Attitude and Meat Consumption Behavior)

  • 강종헌;정항진
    • 한국생활과학회지
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    • 제17권1호
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    • pp.141-150
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    • 2008
  • The purpose of this study was to assess the causal relationships among hedonic belief, ambivalence, subjective norm, attitude and meat consumption behavior. A total of 318 questionnaires were completed. Structural equation model was used to measure the causal effects of constructs. Results of the study demonstrated that fit of the restricted baseline model is significantly worse than that of the unrestricted proposed model, in which more parameters are estimated. The effects of hedonic belief, ambivalence and subjective norm on attitude were statistically significant. The effects of hedonic belief, subjective norm and attitude on meat consumption were statistically significant. The effect of attitude on intention was statistically significant. Moreover, attitude played a mediating role in the relationships between hedonic belief and meat consumption, between ambivalence and meat consumption, and between subjective norm and intention. This study suggested that the consumer decision-making process for eating meat products is best modeled as a complex system that incorporates both direct and indirect effects on meat consumption. This study believed the evidence presented supports this position. Moreover, this study appeared to be a worthy area of pursuit.

김세화 교수의 반론과 활성 경로 이론의 제한 및 확장 (The Active-Route Account Restricted and Expanded: A Reply to Seahwa Kim's Criticisms)

  • 김성수
    • 논리연구
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    • 제18권2호
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    • pp.265-289
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    • 2015
  • 인과 관계가 결과와 원인 간의 반사실적 의존 관계로 분석될 수 있다는 직관은 설득력이 있다. 활성 경로 이론은 단순한 형태의 반사실적 인과 이론의 문제점을 피하면서도 이 직관을 유지하기 위해 제안된 이론이다. 하지만 이 이론 역시 심각한 반례에 직면한다. 김세화 교수는 최근의 논문에서 이러한 반례를 반박하고자 제시된 기존의 해결책이 갖는 문제점을 설득력 있게 비판하였다. 이 논문은 김세화 교수의 비판을 논의하고 더 나아가 활성 경로 이론에 대한 반례를 극복할 수 있는 또 다른 해결책을 논의한다. 특히 활성 경로 이론의 적용 범위를 제한하고 이렇게 제한된 이론을 다시 확장하는 방식을 제시함으로써 활성 경로 이론을 그 반례로부터 방어하는 방법을 제안한다.

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시스템 다이내믹스의 정책지렛대를 활용한 RTE 핵심성공요인 도출에 관한 연구 (Critical Success Factors of RTE Based on Policy Leverage of System Dynamics)

  • 정재운;김현수;최형림;홍순구
    • 한국정보시스템학회지:정보시스템연구
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    • 제16권4호
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    • pp.177-194
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    • 2007
  • This study is intended to identify critical success factors(CSF) of real-time enterprises(RTE) by using a policy leverage method of system dynamics. Since RTE is a new theoretical system that unifies existing theories or concepts in business management and information technology, it is not proper to employee a traditional statistical method. To obtain our research goal, causal maps of system dynamics are employed to abstract and arrange RTE information from previous studies. By using the commonness of policy leverage and critical success factors, CSFs for the RTE are deduced by substituting the leverage points on causal maps with necessary success factors to solve the problems. Since this is a new approach to identify success factors. it has some restrictions. Unlike the statistical methods, this approach explains only the directions of causalities and correlations. For the future research, a simulation tool of system dynamics can be employed to discover how each CSF is correlated to the successful implementation of RTE.

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외국인투자가 탄소배출량에 미치는 영향분석: 패널 VAR 모형을 이용한 분석 (Analysis of the Influence of Foreign Direct Investment on Carbon Emissions: Analysis Using Panel VAR Model)

  • 류승우;이양기;김능우
    • 무역학회지
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    • 제44권1호
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    • pp.45-56
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    • 2019
  • The purpose of this study is to investigate the relationship between foreign investment and carbon emissions in the Korean electricity sector, the causal relationship between the foreign investment invested in the electric power sector in the 16 regional regions and the carbon emissions in the region, The purpose of this study is to analyze the effects of foreign investment on these sectors and the carbon footprint of these sectors using Panel Random Effect Analysis, Panel VAR and OLS models. A panel analysis of foreign investment and regional carbon emissions showed that there was a causal relationship. Based on this analysis, OLS analysis showed that 7 out of 16 metropolitan areas were foreign investment And carbon emissions were significant. In the remaining six regions except Gwangju, there was a causal relationship between foreign investment in the local power sector and the reduction of carbon emissions. After categorizing the electric power industry by device, process, purpose and number of employees, causality also appeared in relation to foreign investment in these sectors and their carbon emissions. Through this study, the authors suggest that foreign investment can be a way to solve not only the financial burden of carbon emission problem, but also the development of national economy and industry through the inflow of capital and advanced new technology.

Exploration of errors in variance caused by using the first-order approximation in Mendelian randomization

  • Kim, Hakin;Kim, Kunhee;Han, Buhm
    • Genomics & Informatics
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    • 제20권1호
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    • pp.9.1-9.6
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    • 2022
  • Mendelian randomization (MR) uses genetic variation as a natural experiment to investigate the causal effects of modifiable risk factors (exposures) on outcomes. Two-sample Mendelian randomization (2SMR) is widely used to measure causal effects between exposures and outcomes via genome-wide association studies. 2SMR can increase statistical power by utilizing summary statistics from large consortia such as the UK Biobank. However, the first-order term approximation of standard error is commonly used when applying 2SMR. This approximation can underestimate the variance of causal effects in MR, which can lead to an increased false-positive rate. An alternative is to use the second-order approximation of the standard error, which can considerably correct for the deviation of the first-order approximation. In this study, we simulated MR to show the degree to which the first-order approximation underestimates the variance. We show that depending on the specific situation, the first-order approximation can underestimate the variance almost by half when compared to the true variance, whereas the second-order approximation is robust and accurate.