• Title/Summary/Keyword: Cas1-Cas2

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X-ray observation of the shocked red supergiant wind of Cassiopeia A

  • Lee, Jae-Joon;Park, Sang-Wook
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.104.2-104.2
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    • 2011
  • We study X-ray characteristics of shocked ambient gas of the Galactic core-collapse supernova remnant Cas A. Using 1 Msec observation with Chandra X-ray Observatory, we identify thermal emissions from the shocked ambient gas along the outer boundary of the remnant. Our results show that Cas A is expanding into a circumstellar wind with a wind density n ~ 1 $cm^{-3}$ at the current outer radius of the remnant (~ 3 pc). We suggest that the progenitor star of Cas A, which exploded as a Type~IIb SN, had an initial mass ~16 Msun, and have lost ~10 Msun as a RSG wind. We discuss the implications of our results for the mass loss of massive stars and the resulting supernova type.

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Sensitivity Analysis for CAS500-4 Atmospheric Correction Using Simulated Images and Suggestion of the Use of Geostationary Satellite-based Atmospheric Parameters (모의영상을 이용한 농림위성 대기보정의 주요 파라미터 민감도 분석 및 타위성 산출물 활용 가능성 제시)

  • Kang, Yoojin;Cho, Dongjin;Han, Daehyeon;Im, Jungho;Lim, Joongbin;Oh, Kum-hui;Kwon, Eonhye
    • Korean Journal of Remote Sensing
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    • v.37 no.5_1
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    • pp.1029-1042
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    • 2021
  • As part of the next-generation Compact Advanced Satellite 500 (CAS500) project, CAS500-4 is scheduled to be launched in 2025 focusing on the remote sensing of agriculture and forestry. To obtain quantitative information on vegetation from satellite images, it is necessary to acquire surface reflectance through atmospheric correction. Thus, it is essential to develop an atmospheric correction method suitable for CAS500-4. Since the absorption and scattering characteristics in the atmosphere vary depending on the wavelength, it is needed to analyze the sensitivity of atmospheric correction parameters such as aerosol optical depth (AOD) and water vapor (WV) considering the wavelengths of CAS500-4. In addition, as CAS500-4 has only five channels (blue, green, red, red edge, and near-infrared), making it difficult to directly calculate key parameters for atmospheric correction, external parameter data should be used. Therefore, thisstudy performed a sensitivity analysis of the key parameters (AOD, WV, and O3) using the simulated images based on Sentinel-2 satellite data, which has similar wavelength specifications to CAS500-4, and examined the possibility of using the products of GEO-KOMPSAT-2A (GK2A) as atmospheric parameters. The sensitivity analysisshowed that AOD wasthe most important parameter with greater sensitivity in visible channels than in the near-infrared region. In particular, since AOD change of 20% causes about a 100% error rate in the blue channel surface reflectance in forests, a highly reliable AOD is needed to obtain accurate surface reflectance. The atmospherically corrected surface reflectance based on the GK2A AOD and WV was compared with the Sentinel-2 L2A reflectance data through the separability index of the known land cover pixels. The result showed that two corrected surface reflectance had similar Seperability index (SI) values, the atmospheric corrected surface reflectance based on the GK2A AOD showed higher SI than the Sentinel-2 L2A reflectance data in short-wavelength channels. Thus, it is judged that the parameters provided by GK2A can be fully utilized for atmospheric correction of the CAS500-4. The research findings will provide a basis for atmospheric correction of the CAS500-4 in the future.

In vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wild-type animal

  • Chang, Yoo Jin;Bae, Jihyeon;Zhao, Yang;Lee, Geonseong;Han, Jeongpil;Lee, Yoon Hoo;Koo, Ok Jae;Seo, Sunmin;Choi, Yang-Kyu;Yeom, Su Cheong
    • Journal of Veterinary Science
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    • v.21 no.2
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    • pp.26.1-26.14
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    • 2020
  • Pancreatic ductal adenocarcinoma is a lethal cancer type that is associated with multiple gene mutations in somatic cells. Genetically engineered mouse is hardly applicable for developing a pancreatic cancer model, and the xenograft model poses a limitation in the reflection of early stage pancreatic cancer. Thus, in vivo somatic cell gene engineering with clustered regularly interspaced short palindromic repeats is drawing increasing attention for generating an animal model of pancreatic cancer. In this study, we selected Kras, Trp53, Ink4a, Smad4, and Brca2 as target genes, and applied Campylobacter jejuni Cas9 (CjCas9) and Streptococcus pyogens Cas9 (SpCas9) for developing pancreatic cancer using adeno associated virus (AAV) transduction. After confirming multifocal and diffuse transduction of AAV2, we generated SpCas9 overexpression mice, which exhibited high double-strand DNA breakage (DSB) in target genes and pancreatic intraepithelial neoplasia (PanIN) lesions with two AAV transductions; however, wild-type (WT) mice with three AAV transductions did not develop PanIN. Furthermore, small-sized Cjcas9 was applied to WT mice with two AAV system, which, in addition, developed high extensive DSB and PanIN lesions. Histological changes and expression of cancer markers such as Ki67, cytokeratin, Mucin5a, alpha smooth muscle actin in duct and islet cells were observed. In addition, the study revealed several findings such as 1) multiple DSB potential of AAV-CjCas9, 2) peri-ductal lymphocyte infiltration, 3) multi-focal cancer marker expression, and 4) requirement of > 12 months for initiation of PanIN in AAV mediated targeting. In this study, we present a useful tool for in vivo cancer modeling that would be applicable for other disease models as well.

A Study on Method of Automatic Geospatial Feature Extraction through Relative Radiometric Normalization of High-resolution Satellite Images (고해상도 위성영상의 상대방사보정을 통한 자동화 지향 공간객체추출 방안 연구)

  • Lee, Dong-Gook;Lee, Hyun-Jik
    • Korean Journal of Remote Sensing
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    • v.36 no.5_2
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    • pp.917-927
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    • 2020
  • The Ministry of Land, Infrastructure and Transport of Korea is developing a CAS 500-1/2 satellite capable of photographing a GSD 0.5 m level image, and is developing a technology to utilize this. Therefore, this study attempted to develop a geospatial feature extraction technique aimed at automation as a technique for utilizing CAS 500-1/2 satellite images. KOMPSAT-3A satellite images that are expected to be most similar to CAS 500-1/2 were used for research and the possibility of automation of geospatial feature extraction was analyzed through relative radiometric normalization. For this purpose, the parameters and thresholds were applied equally to the reference images and relative radiometric normalized images, and the geospatial feature were extracted. The qualitative analysis was conducted on whether the extracted geospatial feature is extracted in a similar form from the reference image and relative radiometric normalized image. It was also intended to analyze the possibility of automation of geospatial feature extraction by quantitative analysis of whether the classification accuracy satisfies the target accuracy of 90% or more set in this study. As a result, it was confirmed that shape of geospatial feature extracted from reference image and relative radiometric normalized image were similar, and the classification accuracy analysis results showed that both satisfies the target accuracy of 90% or more. Therefore, it is believed that automation will be possible when extracting spatial objects through relative radiometric normalization.

A Novel Collision Avoidance System to Prevent Navigator's Human Error - Development Concepts - (해기사 인적오류 예방이 가능한 새포운 선박충돌회피 시스템 개발 개념)

  • Yim, Jeong-Bin
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2019.11a
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    • pp.264-264
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    • 2019
  • The purpose of this paper is to establish development concepts for a novel collision avoidance system with preventing function of navigator's human error (Hu-CAS) in ship control behaviors. Hu-CAS consists of four modules: 1) collision risk assessment module to estimate collision priority between the ship and objects, 2) decision-making module to decide collision risk levels, 3) parameter estimation module needed in the ship control to avoid collisions and 4) control system to control the rudder angle and speed. Hu-CAS, proposed in this paper, can provide a novel system substitution current Autopilot and/or a CAS be teen manned vessel and Autonomous ship in a future.

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Photosensitization Effect and Structure-Activity on Mutagenic Potential by 4-(Nitrobenzyl)Pyridine (4-NBP) Test, of Epoxides, Olefins and Alkylating Agents (4-(Nitrobenzyl)Pyridine에 의한 에폭시드 및 알킬화합물의 변이원성 잠재력에 대한 구조활성 및 광화학효과의 연구)

  • 김재현;엄애선
    • Journal of Environmental Health Sciences
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    • v.27 no.2
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    • pp.43-50
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    • 2001
  • This paper reviews the results of a series of efforts to develop structure-activity models for slow-reacting chemicals and olefins whose toxicity may be enhanced by the ultraviolet radiation. Photoinduced toxicity of 14 compounds was found to be a different result of competing factors of structure, having carbon-carbon double bonds. To mimic the biological consequences of photooxidative damage in mammalian cells, the photochemical mutagenicith of 14 chemicals was tested in the CAS. Simple olefins were photochemically mutagenic or carcinogenic with irradiation, increasing the alkylating activity from zero level to 0.87(abs/gram) for styrene, 0.25 for 1-butene, 0.11 for 1-hexene, respectively, whereas no photochemical mutagenicity was observed with 1-octene in the absence of the CAS. Oxide compounds, however, showed a decreasing trend of photoalkylating activities in the presence or absence of the CAS. We found that the structure-activity relationship was not applicable to our data.

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Investigation on Preparation of Ge Quantum Dots in $SiO_2$ Thin Films

  • Chen, Jing;Wu, Xuemei;Jin, Zongming;Yao, Weiguo
    • Journal of the Korean Vacuum Society
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    • v.7 no.s1
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    • pp.197-201
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    • 1998
  • Ge quantum dots in $SiO_2$ thin films were prepared by r.f. magnetron co-sputtering using a Ge, $SiO_2$ composite target. The size of quantum dots was modulated by controlling of substrate temperature during depositing and annealing of samples deposited at certain substrate temperature. A series of work was done on the influence of preparing parameters on the growth of quantum dots, and a discussion on the formation and growth of quantum dots under different preparation parameters is given.

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Gel Properties of Mook Manufactured from Acorns Harvested in Various Countries according to Storage Period (수입 원산지별 도토리묵의 저장기간에 따른 겔화 특성)

  • Yang, Kee-Heun;Lee, Kun-Jong;Kim, Mee-Ree
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.8
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    • pp.1168-1175
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    • 2012
  • Gel properties of Mook manufactured from acorn harvested in various countries [domestic (KAS), Chinese (CAS), and North Korea (NAS)] were analyzed according to storage period. Gel properties included water binding, syneresis of gel, DSC (differential scanning calorimetry), X-ray diffraction, SEM (scanning electron microscopy), texture, Hunter's color value, and sensory value. Water binding of NAS, CAS, and KAS were 233.8%, 217.3%, and 215.0%, respectively. Syneresis of gel from KAS, CAS, and NAS were 2.06%, 1.85%, and 1.45%, respectively, after 1 day of storage. There were significant differences upon storage for 1~3 days (p<0.05), whereas were no significant differences upon storage for 4~10 days. Peak temperature of gelatinization property by DSC was $55.28^{\circ}C$ for KAS, $54.45^{\circ}C$ for CAS, and $54.12^{\circ}C$ for NAS after 1 day of storage. Hardness of texture in NAS, KAS, and CAS were 374.9, 357.4, and 348.9, respectively, after 1 day of storage. Hunter's color L value, and a value were highest in NAS, whereas b value was the lowest in CAS. There were no significant differences in any particular sensory values.

Direct numerical simulation of passive scalar in decaying compressible turbulence

  • Li Xinliang;Fu Dexun;Ma Yanwen
    • 한국전산유체공학회:학술대회논문집
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    • 2003.10a
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    • pp.39-41
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    • 2003
  • n this paper, direct numerical simulation of decaying compressible turbulence with passive scalar is performed by using 7th order upwind difference scheme or 8th order group velocity control scheme. The start Reynolds number (defined by Taylor scale) is 72 and turbulent Mach numbers are 0.2-0.9. The Schmidt numbers of passive scalar are 2-10. The Batchelor k-1 range are found in scalar spectra, and the high wavenumber spectra decays faster with increasing turbulent Mach number. The extend self-similarity (ESS) is found in the passive scalar in compressible turbulence.

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Factors of Food Adaptation and Changes of Food Habit on Koreans Residing in America (미국 거주 한국인의 식생활 적응에 영향을 미치는 요인 및 식습관 변화)

  • Park, Eun-Sook
    • Journal of the Korean Society of Food Culture
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    • v.12 no.5
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    • pp.519-529
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    • 1997
  • The purpose of this study was to investigate the factors of food adaptation and the changes of food habit on Koreans residing in America. The subject was 89 Koreans residing in Knoxville, TN. The survey was undertaken from October to December of 1995. Demographic characteristics, food behavior, composite adaptation score(CAS), composition of Korean and American foods in 1 day, and frequence and preference changes of foods was determined. The results were summarized as fellows : The mean CAS for all subjects was 17.6 with individual scores ranging from 9 to 23. The CAS were significantly different in residing age, American friends, English speaking ability, eat with Koreans, American food experience before, American food experience now, breakfast type in weekday, breakfast type in weekday, and self-food habits change at p<0.05. No significant differences in CAS could be attributed to sex, marital status, children, and job. Food consumption patterns for breakfast was Korean style 58%, American style 39.3%. For lunch both style was almost same, and for supper Korean style was 78.2%. The intake of food most frequent was rice, and then Kimchee. The preference of Korean foods was increased, though the frequence was decreased. The preference and frequence of American foods were increased respectively.

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