• Journal of the East Asian Society of Dietary Life
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• v.22 no.6
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• pp.772-781
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• 2012

This study was conducted to examine the development of a new anti-inflammatory substance with potent anti-inflammatory activities that was derived from the Platycodi Radix butanol fraction. To accomplish this, the chemical structures and anti-inflammatory activities of the components were elucidated. Upon column chromatography of the tertiary subfraction, fractions 8-4-1 and 8-4-2 were identified as platycodin D and D3, respectively, following recrystallization, based on melting point (MP), infrared (IR), and positive fast atom bombardment (FAB)-mass and nuclear magnetic resonance (NMR) spectral data. Platycodin D and D3 exhibited strong anti-inflammatory activities in rats when administerd at oral doses of 12 mg/kg and 36 mg/kg, p.o., respectively. Platycodin D and D3 induced inhibitory effects on capillary vascular permeability in rats at oral doses of 16 mg/kg and 24 mg/kg, p.o., respectively, and potent inhibition of leukocyte emigration in a carboxymethyl cellulose (CMC)-pouch when administered at doses of 3 mg/rat and 7 mg/rat, s.c., respectively. These results verified the high antiinflammatory potency of the platycodin D and D3 components in Platycodi Radix.

• Journal of the Korean Society of Mechanical Technology
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• v.13 no.4
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• pp.1-7
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• 2011

The paper concerns numerical study of fully developed laminar flow of a Newtonian water and non-Newtonian fluids, 0.2% aqueous of sodium carboxymethyl cellulose(CMC) solution in eccentric annuli with combined bulk axial flow and inner cylinder rotation. Pressure losses and skin friction coefficients have been measured when the inner cylinder rotates at the speed of 0~200 rpm. A numerical analysis considered mainly the effects of annular eccentricity and inner cylinder rotation. The present analysis has demonstrated the importance of the drill pipe rotation and eccentricity. In eccentricity of 0.7 of a Newtonian water, the flow field is recirculation dominated and unexpected behavior is observed. it generates a strong rotation directed layer, that two opposing effects act to create two local peaks of the axial velocity. The influences of rotation, radius ratio and working fluid on the annular flow field are investigated.

• Journal of Electrochemical Science and Technology
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• v.12 no.1
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• pp.74-81
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• 2021

Silicon (Si) is recognized as a promising anode material for high-energy-density lithium-ion batteries. However, under a condition of electrode comparable to commercial graphite anodes with low binder content and a high electrode density, the practical use of Si is limited due to the huge volume change associated with Si-Li alloying/de-alloying. Here, we report a novel core-shell composite, having a reversible capacity of ~ 500 mAh g-1, by forming a shell composed of a mixture of nano-Si, graphite nanosheets and a pitch carbon on a spherical natural graphite particle. The electrochemical measurements are performed using electrodes with 2 wt % styrene butadiene rubber (SBR) and 2 wt.% carboxymethyl cellulose (CMC) binder in an electrode density of ~ 1.6 g cm-3. The core-shell composites having the reversible capacity of 478 mAh g-1 shows the outstanding capacity retention of 99% after 100 cycles with the initial coulombic efficiency of 90%. The heterostructure of core-shell composites appears to be very effective in buffering the volume change of Si during cycling.

• Journal of the Korean Society of Industry Convergence
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• v.24 no.6_2
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• pp.737-744
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• 2021

An investigation is conducted to study a solid-liquid mixture vertically upward hydraulic transport of solid particles by non-Newtonian fluids in the Mud system. Rheology of particulate suspensions in viscoelastic fluids is of importance in many applications such as particle removal from surfaces, transport of proppants in fractured reservoir and cleaning of drilling holes, etc. In this study a clear acrylic pipe was used in order to observe the movement of solid particles. Annular velocities varied from 0.4 m/s to 1.2 m/s. The mud systems which were utilized included aqueous solution of sodium carboxymethyl cellulose (CMC) solutions. Main parameters considered in the study were inner-pipe rotary speed, fluid flow regime and particle injection rate. Solid volumetric concentration and pressure drops were measured for the various parameters such as inclination angle, flow rate, and rotational speed of inner cylinder.

• Korean Journal of Medicinal Crop Science
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• v.14 no.3
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• pp.130-133
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• 2006

This study was conducted to select Codonopsis lanceolata seed's new pelleting particulate materials and adhesives. Different adhesives (Polyvinyl alcohol (PVA), Carboxymethyl cellulose (CMC), Polyvinyl pyrrolidone (PVP), Xanthan gum (XG), Arabic gum (AG)) and particulate materials (Illite, Diatomite, Pyrophyllite + Illite + Diatomite (PID), Pyrophyllite + Illite + Talc (PIT), Bentonite + Talc (BT)) were tested for seed pelleting. PID for Codonopsis lanceolata seed pelleting appeared to be the best particulate material. Among the pelleting adhesives, PVP was the best adhesive for seed pelleting, and the optimum concentration for germination of pelleting seed was 1 %. Germination rate of the pelleted seeds treated with PID particulate material and PVP adhesive was higher (86.8%) than those of raw seeds (85.5%). $T_{50}$ and MDG of pelleted Codonopsis lanceolata seed required five and eight days at soil moisture content of 50%, respectively.

• Journal of Microbiology and Biotechnology
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• v.30 no.10
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• pp.1559-1566
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• 2020

Compound K (C-K) is one of the most pharmaceutically effective ginsenosides, but it is absent in natural ginseng. However, C-K can be obtained through the hydrolysis of protopanaxadiol-type ginsenosides (PPDGs) in natural ginseng. The aim of this study was to obtain the high concentration of food-available C-K using PPDGs in Korean ginseng extract by an extracellular enzyme from Aspergillus niger KACC 46495. A. niger was cultivated in the culture medium containing the inducer carboxymethyl cellulose (CMC) for 6 days. The extracellular enzyme extracted from A. niger was prepared from the culture broth by filtration, ammonium sulfate, and dialysis. The extracellular enzyme was used for C-K production using PPDGs. The glycoside-hydrolyzing pathways for converting PPDGs into C-K by the extracellular enzyme were Rb1 → Rd → F2 → C-K, Rb2 → Rd or compound O → F2 or compound Y → C-K, and Rc → Rd or compound Mc1 → F2 or compound Mc → C-K. The extracellular enzyme from A. niger at 8.0 mg/ml, which was obtained by the induction of CMC during the cultivation, converted 6.0 mg/ml (5.6 mM) PPDGs in Korean ginseng extract into 2.8 mg/ml (4.5 mM) food-available C-K in 9 h, with a productivity of 313 mg/l/h and a molar conversion of 80%. To the best of our knowledge, the productivity and concentration of C-K of the extracellular enzyme are the highest among those by crude enzymes from wild-type microorganisms.

• Korean Journal of Agricultural Science
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• v.25 no.1
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• pp.124-130
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• 1998

An alkalophilic bacterium, the strain AC-711 as a potent producer of alkaline cellulase, was selected among many isolates from soil environments. Morphological, physiological and chemical characteristics of the strain AC-711 suggested that it belongs to the genus Pseudomonas according to the Bergey's Manual of Systematic Bacteriology, however the G+C mol% (54.43) of its chromosomal DNA is lower than the normal values of the genus. The major cell wall fatty acids were determined as 15:0 and 17:0 anteiso. The production of alkaline CMCase by the strain was maximal when grown on the mediun containing 1% carboxymethyl cellulose, 0.1% $KH_2PO_4$, 0.02% $CoCl_2$, 0.02% Tween 80, 0.5% $Na_2CO_3$, 0.8% yeast extract, pH 10.3 at $30^{\circ}C$ for 3 days, and the most of enzyme was excreted into culture mediun.

• Journal of Applied Biological Chemistry
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• v.60 no.3
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• pp.257-263
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• 2017

A cellulolytic strain Y2 was isolated from soil obtained in the Canadian Alpine region. The isolate was identified as Paenibacillus sp. Y2 by 16S rRNA sequencing. When grown in LB medium supplemented with carboxymethyl-cellulose (CMC), CMCase production increased to 122.0% of that observed in LB without CMC. Culture supernatant was concentrated by ultrafiltration and 80% ammonium sulfate precipitates were separated by Hi-Trap Q and CHT-II chromatography. The purified enzyme (EG-PY2) showed a homogeneous single band and the molecular mass was estimated to be 38 kDa by SDS-PAGE. Optimum pH and temperature of the enzyme were 4.5 and $30^{\circ}C$, respectively. The half-life of enzyme activity at 50 was 140.7 min, but the enzyme was drastically inactivated within 5 min at $55^{\circ}C$. The enzyme was highly activated to 135.7 and 126.7% by 5.0 mM of $Cu^{2+}$ or $Mg^{2+}$ ions, respectively, and moderately activated by $Ba^{2+}$ and $Ca^{2+}$ ions, whereas it was inhibited to 76.8% by $Fe^{2+}$, and to ${\leq}50%$ by $Mn^{2+}$, $Co^{2+}$, $Zn^{2+}$, and EDTA. The enzyme was activated to 211.5% in the presence of 0.5 M of NaCl and greatly tolerant to 3.15M of NaCl. The enzyme showed 2.98 times higher ${\beta}$-glucanase activity than CMCase activity. Based on these results, it can be concluded that EG-PY2 is an acidophilic, cold-active, and halotolerant endoglucanase. The authors suggest it is considered to be useful for various industrial applications, such as, fruit juice clarification, acidic deinking processes, high-salt food processing, textile and pulp industries, and for biofuel production from seaweeds.

• Korean Journal of Food Science and Technology
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• v.27 no.6
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• pp.928-933
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• 1995

Sensory and instrumental characteristics of mixed starch gels of defatted corn starch and mung bean starch were examined in terms of the effects of various additives such as textured soy protein(TSP), soybean oil(S0), carboxymethyl cellulose(CMC) and pectin(PC). Gels were prepared by storing the paste at room temperature for 24 hrs and 72 hrs. The additives were used 1% or 2% on the starch basis. The ratio of defatted corn starch and mung bean starch was selected 60 : 40(to, w/w), where the acceptability was the highest. The cohesiveness and springiness of the mixed starch gels stored 24 hrs increased, but the brittleness and acceptability decreased with all the additives. Textural characteristics of the mixed gels stored 72 hrs were different according to the type and content of additives, whereas hardness and cohesiveness increased in all case. Unlike the sensory evaluation, the textural properties of mixed gels tested by a Instron Universal Testing Machine showed no difference in hardness, but the cohesiveness and springiness increased.

• KSBB Journal
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• v.7 no.1
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• pp.59-65
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• 1992

Hydrodynamics and mixing characteristics such as circulation time, mixing time, circulation velocity and axial dispersion coefficient were investigated using highly viscous pseudoplastic solutions of carboxymethyl cellulose(CMC) in an external circulation loop air-lift reactor with 13$\ell$ working volume. The superficial gas velocity was changed from 1.9 to 6.2cm/s and CMC concentration from 0 to 1.0wt%. The theoretical model based on the pressure balance is developed mathematically to predict liquid circulation velocity. Gas hold-up, circulation velocity and axial dispersion coefficient of liquid phase increased with increasing gas velocity and decreased slightly with increasing liquid viscosity. Mixing time and circulation time decreased with increasing gas velocity and increased with increasing liquid viscosity. Experimental data on liquid circulation velocity were in good agreement with the predicted values.