• 센서학회지
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• 제32권3호
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• pp.131-139
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• 2023

Ascorbic acid plays a crucial role in the regulation of neurotransmitters and enzymes in the central nervous system. Maintaining an optimal level of ascorbic acid, which is between 0.6-2 mg/dL, is vital for preventing oxidative stress and associated health conditions, such as cancer, diabetes, and liver disease. Therefore, the detection of ascorbic acid is of the utmost importance. Electrochemical sensing has gained significant attention among the various detection methods, owing to its simplicity, speed, affordability, high selectivity, and real-time analysis capabilities. However, conventional electrodes have poor signal response, which has led to the development of modified electrodes with better signal response and selectivity. Carbon nanotubes (CNTs) and their composites have emerged as promising materials for the electrochemical detection of ascorbic acid. CNTs possess unique mechanical, electrical, and chemical properties that depend on their structure, and their large surface area and excellent electron transport properties make them ideal candidates for electrochemical sensing. Recently, various CNT composites with different materials and nanoparticles have been studied to enhance the electrochemical detection of ascorbic acid. Therefore, this review aims to highlight the significance of CNTs and their composites for improving the sensitivity and selectivity of ascorbic acid detection. Specifically, it focuses on the use of CNTs and their composites in electrochemical sensing to revolutionize the detection of ascorbic acid and contribute to the prevention of oxidative stress-related health conditions. The potential benefits of this technology make it a promising area for future research and development.

• 한국전기전자재료학회논문지
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• 제31권4호
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• pp.231-237
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• 2018

In this study, two important requirements for the home production of a robot to detect and remove improvised explosive devices (IEDs) are presented in terms of the total cost for robot system development and the performance improvement of the mine detection technology. Firstly, cost analyses were performed in order to provide a reasonable solution following an engineering estimate method. As a result, the total cost for a mass production system without the mine detection system was estimated to be approximately 396 million won. For the case including the mine detection system, the total cost was estimated to be approximately 411 million won, in which labor costs and overhead charges were slightly increased and the material costs for the mine detection system were negligible. Secondly, a method for fabricating the carbon nanotube (CNT) based gas detection sensor was studied. The detection electrodes were formed by a photolithography process using a photosensitive CNT paste. As a result, this method was shown to be a scalable and expandable technology for producing excellent mine detection sensors. In particular, it was found that surface treatments by using adhesive taping or ion beam bombardment methods are effective for exposing the CNTs to the ambient air environment. Fowler-Nordheim (F-N) plots were obtained from the electron-emission characteristics of the surface treated CNT paste. The F-N plot suggests that sufficient electrons are available for transport between CNT surfaces and chemical molecules, which will make an effective chemiresistive sensor for the advanced IED detection system.

• 센서학회지
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• 제32권1호
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• pp.44-50
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• 2023

In this study, a polydimethylsiloxane (PDMS)-based drag force-type flowmeter was fabricated using a graphite-carbon nanotube (CNT) composite as a piezoresistive material and evaluated. The device was in the form of a cantilever, which was composed of the soft material, PDMS, and fabricated using a mold manufactured by a three-dimensional printer. The cost-effective graphite was mixed with CNTs to serve as a piezoresistive material. The optimal mixing ratio was investigated, and the piezoresistive material formed using a graphite:PDMS:CNT ratio of 1.5:1:0.01 was adopted, which showed a stable output and a high sensitivity. Various forward and backward air flows in the range of 0-10 m/s were measured using the fabricated flowmeter, and both tensile and compression characteristics were evaluated. The measured results showed a stable output, with the resistance change gradually increasing with the air flow rate. Repeatability characteristics were also tested at a repeated air flow of 10 m/s, and the flowmeter responded to the applied air flow well. Consequently, the fabricated device has a high sensitivity and can be used as a flowmeter.

• 대한전자공학회논문지SD
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• 제48권9호
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• pp.31-39
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• 2011

본 논문에서는 Carbon Nanotube(CNT) 센서 어레이를 위한 저 전력, 소 면적의 신호 검출 시스템을 제안한다. 제안된 시스템은 신호 검출회로, 디지털 제어기, UART I/O로 구성된다. 신호 검출회로는 VGA를 공유하는 64개의 transimpedance amplifier(TIA)와 11비트 해상도의 successive approximation register-ADC(SAR-ADC)를 사용하였다. TIA는 센서의 전압 바이어스 및 전류를 증폭하기 위한 active input current mirror(AICM)와 증폭된 전류를 전압으로 변환하는 저항 피드백 방식의 VGA(Variable Gain Amplifier)로 구성되어있다. 이러한 구조는 큰 면적과 많은 전력을 필요로 하는 VGA를 공유하기 때문에 다수의 센서 어레이에 대해 검출 속도의 저하 없이 저 전력, 소 면적으로 신호 검출이 가능하게 한다. SAR-ADC는 저 전력을 위하여 입력 전압 level에 따라 하위 bit의 동작을 생략하는 수정된 알고리즘을 사용하였다. ADC 및 센서의 선택은 UART Protocol 기반의 디지털 제어기에 의해 선택되며, ADC의 data는 UART I/O를 통해 컴퓨터와 같은 단말기를 통해 모니터링 할 수 있다. 신호 검출회로는 0.13${\mu}m$ CMOS 공정으로 설계되었으며 면적은 0.173 $mm^2$이며 640 sample/s의 속도에서 77.06${\mu}W$의 전력을 소모한다. 측정 결과 10nA - 10${\mu}A$의 전류 범위에서 5.3%의 선형성 오차를 가진다. 또한 UART I/O, 디지털 제어기는 0.18${\mu}m$ CMOS 공정을 이용하여 제작하였으며 총면적은 0.251 $mm^2$ 이다.

• 디지털융복합연구
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• 제15권11호
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• pp.231-243
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• 2017

본 논문은 전기적 감지 방식 바이오센서의 개념을 리뷰하고, 의류 및 텍스트 기반의 바이오센서의 연구 사례를 조사하였다. 생체 신호를 측정 할 수 있는 바이오센서는 생물학적 감지 물질을 이용하여 생물학적 물질의 물리적, 화학적 특성을 감지하는 장치이다. 따라서 바이오센서를 사용하여 생체신호를 측정할 수 있는 웰니스 의류는 U-Health 서비스를 제공하는데 중요한 역할을 한다. 기존 센서와 다르게 바이오센서의 차별화된 특징은 선택적 반응과 생물학적 물질의 결합을 사용한다는 점이다. 이러한 바이오센서 중 전기적 감지 바이오센서는 전기 신호의 처리로 인해 크기가 매우 작아 유비쿼터스 환경을 조성하는데 이용될 수 있다. 따라서 웰니스 의류를 개발하기 위해 소형화가 쉬운 전기적 감지 바이오센서를 연구할 필요가 있다. 본 논문에서는 전기적 감지 바이오센서(전기화학적 방식, 나노와이어/탄소나노튜브 기반 FET 방식)에 대해 자세히 기술하였다. 마지막으로, 이러한 고찰을 통해 향후 웰니스 의류에 적용 가능할 바이오센서의 기술개발 방향을 제언하였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.549-549
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• 2012

Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.