• Title/Summary/Keyword: Caps

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Comprehensive comparative analysis of chloroplast genomes from seven Panax species and development of an authentication system based on species-unique single nucleotide polymorphism markers

  • Nguyen, Van Binh;Giang, Vo Ngoc Linh;Waminal, Nomar Espinosa;Park, Hyun-Seung;Kim, Nam-Hoon;Jang, Woojong;Lee, Junki;Yang, Tae-Jin
    • Journal of Ginseng Research
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    • v.44 no.1
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    • pp.135-144
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    • 2020
  • Background: Panax species are important herbal medicinal plants in the Araliaceae family. Recently, we reported the complete chloroplast genomes and 45S nuclear ribosomal DNA sequences from seven Panax species, two (P. quinquefolius and P. trifolius) from North America and five (P. ginseng, P. notoginseng, P. japonicus, P. vietnamensis, and P. stipuleanatus) from Asia. Methods: We conducted phylogenetic analysis of these chloroplast sequences with 12 other Araliaceae species and comprehensive comparative analysis among the seven Panax whole chloroplast genomes. Results: We identified 1,128 single nucleotide polymorphisms (SNP) in coding gene sequences, distributed among 72 of the 79 protein-coding genes in the chloroplast genomes of the seven Panax species. The other seven genes (including psaJ, psbN, rpl23, psbF, psbL, rps18, and rps7) were identical among the Panax species. We also discovered that 12 large chloroplast genome fragments were transferred into the mitochondrial genome based on sharing of more than 90% sequence similarity. The total size of transferred fragments was 60,331 bp, corresponding to approximately 38.6% of chloroplast genome. We developed 18 SNP markers from the chloroplast genic coding sequence regions that were not similar to regions in the mitochondrial genome. These markers included two or three species-specific markers for each species and can be used to authenticate all the seven Panax species from the others. Conclusion: The comparative analysis of chloroplast genomes from seven Panax species elucidated their genetic diversity and evolutionary relationships, and 18 species-specific markers were able to discriminate among these species, thereby furthering efforts to protect the ginseng industry from economically motivated adulteration.

Development of a Korean Type Totally Implantable TAH (한국형 완전이식 인공심장의 개발)

  • Min, B.G.;Choi, W.W.;Ahn, J.M.;Park, S.K.;Park, C.Y.;Chang, J.K.;Kim, J.W.;Kim, H.C.;Kim, W.K.;Roh, R.J.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.199-202
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    • 1996
  • Artificial hearts are intended for use in patients with severe forms of heart disease for which no surgical repair is possible. The moving-actuator pump was developed to decrease the overall volume size of the electromechanical total artificial heart (TAH) by eliminating the occupied space of the fixed-actuator in the conventional pusher-plate type pump. In our pump, the actuator moves back and forth for alternative ejections of left and right ventricles. The problem of fitting the TAH to atrial remnants and arterial vessels could also be improved by circular or penduluous mot ion of the actuator instead of linear mot ion of the pusher-plate in the conventional pumps. We have evaluated two types of moving- actuator pump; one is a rolling cylinder type, and the other a pendulum type pump. In the rolling cylinder pump, frictional energy loss exists between the pump housing's guide bars and the actuator's end caps, while the bottom rack under the cylindrical actuator increases the height of the pump, the pump is therefor not implantable inside the small chest of human-sized animals with a body weight of less than 70kg. The new human type pump has a penduluous mot ion actuator to correct the above problems while maintaining the advantage of the moving- actuator's small total volume. The totally implantable TAH is composed of a blood pump, a control system and pheriperal equipments. The blood pump, which is constructed by a moving actuator, a right and left blood sac, and four artificial valves, is implanted in the thoracic. In 1988, the first implantation of the rolling cylinder TAH was performed into a female calf weighing 100kg, and the cal f recovered to the degree of voluntary standing and eat ing and survived to 100 hrs. We then survived two female sheep weighing about 63kg with the new human type TAH for three days.

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The Reclamation of Tidal Land and the Making-Group of Landscape in Naepo Area, Korea" - Centering around the Garorim Bay from the $19^{th}C$ to 1960s - (내포지역 해만개척의 전개와 경관변화의 사회적 주체 -조선후기~1960년대 가로림만 일대를 중심으로 -)

  • 전종한
    • Journal of the Korean Geographical Society
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    • v.38 no.2
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    • pp.206-223
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    • 2003
  • Bays and caps represent the physical characteristics of Naepo area in Korea. And reclamation of tidal land presents a clue toward the understanding of regional identities and landscape changes in this area. Reclamation of tidal land in the Garorim bay that is representative of the physical geographies of Naepo area had trended toward 'the diffusion of salt ponds' during Joseon dynasty. Hereafter the Japanese imperialism, the reclamation had tumed to 'the reclamation of arable lands' by drainage. But, at the same time the land use of salt pond that had been the most appropriate strategy of adaptation for the ecological environments of this area has showed a sort of the geographical long-term durability. And the great landlords that had emerged during Japanese imperialism were the Yeom-han(鹽漢, laborers who engaged in salt production) in former times. They as a new local elites have played a leading role in the reclamation of tidal land and the making of regional landscape.

Application of Landsat TM/ETM+ Images to Snow Variations Detection by Volcanic Activities at Southern Volcanic Zone, Chile (Landsat TM/ETM+ 위성영상을 활용한 칠레 Southern Volcanic Zone의 화산과 적설변화와의 상관성 연구)

  • Kim, Jeong-Cheol;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
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    • v.33 no.3
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    • pp.287-299
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    • 2017
  • The Southern Volcanic Zone (SVZ) of Chile consists of many volcanoes, including the Mt.Villarrica and Mt.Llaima, and the two volcanoes are covered with snow at the top of Mountain. The purpose of this study is to analyze the relationship between the ice caps and the volcanic activity of the two volcanoes for 25 years by using the satellite image data are available in a time series. A total of 60 Landsat-5 TM and Landsat-7 ETM + data were used for the study from September 1986 to February 2011. Using NDSI (Normalized Difference Snow Index) algorithm and SRTM DEM, snow cover and snowline were extracted. Finally, the snow cover area, lower-snowline, and upper-snowline, which are quantitative indicators of snow cover change, were directly or indirectly affected by volcanic activity, were extracted from the satellite images. The results show that the volcanic activity of Villarrica volcano is more than 55% when the snow cover is less than 20 and the lower-snowline is 1,880 m in Llaima volcano. In addition, when the upper-snowline of the two volcanoes is below -170m, it can be confirmed that the volcano is differentiated with a probability of about 90%. Therefore, the changes in volcanic snowfall are closely correlated with volcanic activity, and it is possible to indirectly deduce volcanic activity by monitoring the snow.

Dynamic Priority Search Algorithm Of Multi-Agent (멀티에이전트의 동적우선순위 탐색 알고리즘)

  • Jin-Soo Kim
    • The Journal of Engineering Research
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    • v.6 no.2
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    • pp.11-22
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    • 2004
  • A distributed constraint satisfaction problem (distributed CSP) is a constraint satisfaction problem(CSP) in which variables and constraints are distributed among multiple automated agents. ACSP is a problem to find a consistent assignment of values to variables. Even though the definition of a CSP is very simple, a surprisingly wide variety of AI problems can be formalized as CSPs. Similarly, various application problems in DAI (Distributed AI) that are concerned with finding a consistent combination of agent actions can be formalized as distributed CAPs. In recent years, many new backtracking algorithms for solving distributed CSPs have been proposed. But most of all, they have common drawbacks that the algorithm assumes the priority of agents is static. In this thesis, we establish a basic algorithm for solving distributed CSPs called dynamic priority search algorithm that is more efficient than common backtracking algorithms in which the priority order is static. In this algorithm, agents act asynchronously and concurrently based on their local knowledge without any global control, and have a flexible organization, in which the hierarchical order is changed dynamically, while the completeness of the algorithm is guaranteed. And we showed that the dynamic priority search algorithm can solve various problems, such as the distributed 200-queens problem, the distributed graph-coloring problem that common backtracking algorithm fails to solve within a reasonable amount of time. The experimental results on example problems show that this algorithm is by far more efficient than the backtracking algorithm, in which the priority order is static. The priority order represents a hierarchy of agent authority, i.e., the priority of decision-making. Therefore, these results imply that a flexible agent organization, in which the hierarchical order is changed dynamically, actually performs better than an organization in which the hierarchical order is static and rigid. Furthermore, we describe that the agent can be available to hold multiple variables in the searching scheme.

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Breeding and cultural characteristics of a newly bred Lentinula edodes strain, 'Bambithyang' (표고 신품종 '밤빛향'의 육성 및 특성)

  • Park, Youngae;Jang, Yeongseon;Ryoo, Rhim;Ka, Kang-Hyeon
    • Journal of Mushroom
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    • v.18 no.2
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    • pp.145-150
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    • 2020
  • A new cultivar, 'Bambithyang', was bred from monokaryotic strains of Sanbaekhyang and SANJO 707ho using the mono-mono hybridization method. Its incubation period was determined to be 100 days and its optimum temperature for fruit body flushing, 11-20℃. The mushrooms had a convex cap (diameter, 69.6 mm; thickness, 15.2 mm) and stipes in their center. The color of their upper sides was chestnut brown; their gills were arranged in a ripple style and had medium density. Their scales were cream-colored and fully distributed; the stipes were cream-colored and cylindrical (thick upper part). They also had cream colored fluffs and sporadic fruiting bodies. Zone lines were present when they were cultivated with mother and father varieties. Their stipe lengths and caps were 9% shorter and 16.9% thicker, respectively, than those of Sanbaekhyang.

The Relationship between Somatic Symptoms and the Trauma-Related Characteristics of Patients with PTSD : A Korean Multicenter Study (다기관 모집 외상 후 스트레스장애 환자에서 외상의 특성과 신체적 증상과의 관계)

  • Shin, Jae-Ho;Choi, Kyeong-Sook;Chae, Jeong-Ho;Woo, Jong-Min;Chee, Ik-Seung;Kim, Jung-Bum;Jeong, Mun-Yong
    • Anxiety and mood
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    • v.4 no.1
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    • pp.34-41
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    • 2008
  • Objective : The aim of this study is to examine the characteristics of somatic symptoms in patients with PTSD according to trauma type. Methods : The subjects of this study were 84 patients diagnosed with PTSD according to the DSM-IVTR and CAPS criteria. The subjects ranged in age from 18 to 76 years, and they were recruited from 18 hospitals across the nation. All participants were asked about their trauma history, and they all completed the Davidson Trauma Scale (DTS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Impact of Event Scale-Revised (IES-R) and Korean-Physical Somatic Symptom Inventory (K-PSI). The items of the K-PSI were categorized into 5 groups according to organ system, and the participants were classified into 6 groups according to trauma type. We compared the results of the social demographical scale, DTS, BDI, STAI, IES-R and each recategorized subscale of the K-PSI among the six groups. Results : There were significant differences between the 6 groups in terms of the Korean-Physical Somatic Symptom Inventory scores for each organ system, except for the cardiopulmonary system, as well as the BDI scores. Post hoc analysis revealed differences between the combat-related trauma group and all other groups but not among any of the other groups. Conclusion : Our result showed that there were significant differences in the somatic symptom scores among the 6 trauma groups. However, patient age and the time elapsed since the traumatic event may have hada crucial influence on the result of this study.

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The Effect of Macroeconomic and Real Estate Policies on Seoul's Apartment Prices (거시경제와 부동산정책이 서울 아파트가격에 미치는 영향 연구)

  • Bae, Jong-Chan;Chung, Jae-Ho
    • Land and Housing Review
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    • v.12 no.4
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    • pp.41-59
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    • 2021
  • This study reviews theoretical considerations and past studies about real estate prices, macroeconomic variables, and real estate policies. Monthly data from January 2003 to June 2021 are used, and a VEC model, the most widely used multivariate time series analysis method, is employed for analysis. Through the model, the effects of macroeconomic variables and real estate regulatory policies on real estate prices in Seoul are analyzed. Findings are summarized as follows. First, macroeconomic variables such as money supply and interest rates do not have a significant impact on Seoul's apartment prices. Due to the high demand for housing and insufficient supply, there is a demand for buying a home regardless of macroeconomic booms or recessions. Second, tax and financial regulatory policies have an initial impact on the rise in apartment prices in Seoul, and their influence diminishes over time. Third, anti-speculation zones are expected to decrease apartment prices through the suppression of demand. However, these zones cause a rise in apartment prices. This could be understood as a lock-in effect due to the strengthening of capital gains tax. Fourth, the price ceiling did not decrease apartment prices. These findings propose that, in Seoul, where demand is high and supply is insufficient, the supply of high-quality and sufficient housing should be prioritized over various regulations such as tax regulations, financial regulations, anti-speculation zones, and price caps. Moreover, the findings provide an implication that city-specific real estate policies should be implemented for Seoul rather than regulation-oriented approaches in public policy.

Characteristics of the Perception of the Somatic Symptoms and the Cognitive Emotion Regulation Strategies in Patients With Posttraumatic Stress Disorder (외상후스트레스장애 환자의 신체증상 지각 특성과 인지적 정서조절전략)

  • Kwon, Joo-Han;Park, Jong-Il;Sakong, Jeong-Kyu;Yang, Jong-Chul
    • Korean Journal of Psychosomatic Medicine
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    • v.29 no.2
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    • pp.102-110
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    • 2021
  • Objectives : The purpose of this study is to investigate the characteristics of the perception of the somatic symptoms and the cognitive emotion regulation strategies in patients with posttraumatic stress disorder (PTSD). Methods : A total of 48 patients meeting DSM-5 criteria for PTSD and 48 normal controls were recruited for participation in this study. We evaluated subjects using Clinician-Administered PTSD Scale (CAPS), Somato-Sensory Amplification Scale (SSAS), Hamilton Anxiety Scale (HAM-A) and Cognitive Emotion Regulation Questionnaire (CERQ). We analyzed data using an independent t-test and Pearson's correlation analysis. Results : In terms of SSAS, PTSD patients presented higher average SSAS scores than normal controls but the result is not statistically significant. In PTSD patients, the severity of PTSD is significantly correlated with CERQ-rumination and CERQ-catastrophizing. The SSAS scores of PTSD patients show the significant positive correlation with PTSD hyperarousal symptoms, CERQ-catastrophizing and CERQ-blaming others. Conclusions : These results reveal that patients with PTSD have maladaptive cognitive emotion regulation strategies such as rumination and catastrophizing. Somato-sensory amplification seems to be related with PTSD hyperarousal, CERQ-catastrophizing and CERQ-blaming others. Therefore, reducing somato-sensory amplification, rumination and catastrophizing can be helpful to reduce PTSD symptoms and somatic symptoms in PTSD patients.

Identification of new Breeding Lines by Prunus Persica Cultivar-Specific SCAR Primers (SCAR 마커 개발 및 이를 활용한 국내 육성 복숭아 품종 판별)

  • Han, Sang Eun;Cho, Kang-Hee;Nam, Eun Young;Shin, Il-Sheob;Kim, Chung Hee;Kim, Hyun Ran;Kim, Dae-Hyun
    • Korean Journal of Breeding Science
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    • v.42 no.5
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    • pp.495-501
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    • 2010
  • Peaches (Prunus persica) are less popular than the fresh fruits, because their flesh gets soft faster. So many breeders focused on their aim to firmness. Other breeders focused on juiciness, flavor and aroma. Breeding requires much labor, time and money. To reduce these requirements, many scientists develop many SSR, CAPS and SCAR makers. New peach varieties bred in our National Institute of Horticultural & Herbal Science (NIHHS) such as, Cheonhong, Suhong and Harhong are yellow flesh cultivars and Yumyeong, Baekmijosaeng, Baekhyang, Jinmi, Soomee, Mihong, Misshong and Yumee are white flesh cultivars. These peach cultivars are planted in orchard of Korea. To assert breeding cultivar patents and prevent patent disputes, we detected cultivar-specific DNA fragment using 235 sets of Operon RAPD primers, analyzed 134 DNA sequences and constructed SCAR primers. To confirm the cultivar-specific SCAR markers, we applied candidate SCAR primers to 30 peach cultivars widely cultivated in Korea. These selected lines are included father and mother lines that were used to develop new varieties in NIHHS. Using fourteen SCAR primer sets, we characterized thirty cultivars selected. The SCAR marker is expected to serve as molecular evidence distinguishing different peach varieties.