• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.3
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• pp.789-791
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• 2004

We study on the video-capillaroscopy system for look a.t the nail fold capillary by the computer. This system is composed of the luminous source-producer, image-input, phase microscope. The method and contents of observation on this system are seperated from the image-analysis of nail fold capillary form-patterns and the currents of hematocytes. Therefore we think this system is possible to the practical clinic use for the basic model on the cardiac failure and the deficiency(血虛), stagnant(血瘀) of blood in human.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.6
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• pp.242-248
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• 2021

This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.

• Journal of Sasang Constitutional Medicine
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• v.25 no.4
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• pp.306-319
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• 2013

Objectives The purpose of this study was to find correlations between gastrointestinal disorders, pain, sleep disorder, fatigue, and to figure out characteristics of fatigue in Sasang Constitution using medical devices data. Methods Sixty three subjects were divided into fatigue group and non-fatigue group, both groups had to undergo blood tests, questionnaire, Sasang constitutional analysis tool (SCAT), pulse wave analyzer examination, heart rate variability examination, nail fold capillary microscopic examination. Results 1) The results of questionnaire about fatigue, gastrointestinal disorder, pain, sleep disorder, quality of life had significant differences between fatigue and non-fatigue groups. 2) Soeumin had more serious gastrointestinal problem and Soyangin had more serious sleep disorder in fatigue groups than non-fatigue groups. 3) According to blood test results, there was no difference between fatigue and non-fatigue groups. 4) Elastic parameter of pulse wave analyzer and nail fold capillary microscopic examination showed significant differences between fatigue and non-fatigue groups in Soyangin. Conclusions We reach the conclusion that fatigue is usually accompanied by gastrointestinal disorder, pain, sleep disorder, deterioration in the quality of life. In Soeumin, treating gastrointestinal disorders can be helpful for treatment of fatigue. In Soyangin, improving sleep disorder may be more effective way to treat fatigue.

• Journal of Periodontal and Implant Science
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• v.52 no.1
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• pp.65-76
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• 2022

Purpose: The present study measured changes in arteriolar and venular capillary flow and structure in the gingival tissues during the development of plaque-induced gingival inflammation by combining dynamic optical coherence tomography (OCT), laser perfusion, and capillaroscopic video imaging. Methods: Gingival inflammation was induced in 21 healthy volunteers over a 3-week period. Gingival blood flow and capillary morphology were measured by dynamic OCT, laser perfusion imaging, and capillaroscopy, including a baseline assessment of capillary glycocalyx thickness. Venular capillary flow was estimated by analysis of the perfusion images and mean blood velocity/acceleration in the capillaroscopic images. Readings were recorded at baseline and weekly over the 3 weeks of plaque accumulation and 2 weeks after brushing was resumed. Results: Perfusion imaging demonstrated a significant reduction of gingival blood flow after 1 and 2 weeks of plaque accumulation (P<0.05), but by 3 weeks of plaque accumulation there was a more mixed picture, with reduced flow in some participants and increased flow in others. Participants with reduced flux at 3 weeks also demonstrated venular-type flow as determined by perfusion images and evidence of the development of venular capillaries as assessed by the velocity/acceleration ratio in capillaroscopic images. After brushing resumed, these venular capillaries were broken down and replaced by arteriolar capillaries. Conclusions: After 3 weeks of plaque accumulation, there was wide variation in microvascular reactions between the participants. Reduced capillary flow was associated with the development of venular capillaries in some individuals. This is noteworthy, as an early increase in venous capillaries is a key vascular feature of cardiovascular disease, psoriasis, Sjögren syndrome, and rheumatoid arthritis-diseases with a significant association with the development of severe gingival inflammation, which leads to periodontitis. Future investigations of microvascular changes in gingival inflammation might benefit from accurate capillary flow velocity measurements to assess the development of venular capillaries.