• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.11A
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• pp.1946-1956
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• 2001

In this paper, we propose a novel 2-D partial matching algorithm based on model-based stochastic analysis of feature correspondences in a relation vector space, which is quite robust to shape variations as well as invariant to geometric transformations. We represent an object using the ARG (Attributed Relational Graph) model with features of a set of relation vectors. In addition, we statistically model the partial occlusion or noise as the distortion of the relation vector distribution in the relation vector space. Our partial matching algorithm consists of two-phases. First, a finite number of candidate sets areselected by using logical constraint embedding local and structural consistency Second, the feature loss detection is done iteratively by error detection and voting scheme thorough the error analysis of relation vector space. Experimental results on real images demonstrate that the proposed algorithm is quite robust to noise and localize target objects correctly even inseverely noisy and occluded scenes.

• Journal of KIISE:Software and Applications
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• v.30 no.12
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• pp.1247-1254
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• 2003

Currently. the north american symptomatic carotid endarterectomy trial, european carotid surgery trial, and common carotid method are used to measure the carotid stenosis for determining candidate for carotid endarterectomy using the projection angiography from different modalities such as digital subtraction angiography. rotational angiography, computed tomography angiography and magnetic resonance angiography. A new computerized carotid stenosis measuring system was developed using MR angiography axial image to overcome the drawbacks of conventional carotid stenosis measuring methods, to reduce the variability of inter-observer and intra-observer. The gray-level thresholding is one of the most popular and efficient method for image segmentation. We segmented the carotid artery and lumen from three-dimensional time-of-flight MRA axial image using gray-level thresholding technique. Using the measured intima-media thickness value of common carotid artery for each cases, we separated carotid artery wall from the segmented carotid artery region. After that, the regions of segmented carotid without artery wall were divided into region of blood flow and plaque. The calculation of carotid stenosis degree was performed as the following; carotid stenosis grading is(area measure of plaque/area measure of blood flow region and plaque) * 100%.

• The KIPS Transactions:PartB
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• v.9B no.5
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• pp.681-688
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• 2002

This paper proposes a system detecting the area of traffic sign, which uses color rate as the information of colors, and corner point and distance rate as the information of morphology. In this system, a candidate area is extracted by performing dilation operation on the binary image made by the color rate of R, G, B components and by detecting corner point and center point through mask. The area of traffic sign with varied shapes is extracted by calculating the distance rate from center point, which is the information of morphology. The results of this experiment demonstrate that in this system which is invariable regardless of its size and location, it is possible to extract the exact area from varied traffic signs such as the shapes of triangle, circle, inverse triangle, and square as well as from the images at both day and night when brightness value is greatly different. Moreover, it demonstrates great accuracy and speed in processing.

• Journal of radiological science and technology
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• v.36 no.2
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• pp.141-148
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• 2013

The CT examination sometimes fail to localize the cerebral hemorrhage part depending on the seriousness and may embarrass the pathologist if he/she is not trained enough for emergencies. Therefore, an assisting role is necessary for examination, automatic and quick detection of the cerebral hemorrhage part, and supply of the quantitative information in emergencies. the computer based automatic detection and recognition system may be of a great service to the bleeding part detection. As a result of this research, we succeeded not only in automatic detection of the cerebral hemorrhage part by grafting threshold value handling, morphological operation, and roundness calculation onto the bleeding part but also in development of the PCA based classifier to screen any wrong choice in the detection candidate group. We think if we apply the new developed system to the cerebral hemorrhage patient in his critical condition, it will be very valuable data to the medical team for operation planning.

• Journal of Korea Multimedia Society
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• v.5 no.4
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• pp.415-425
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• 2002

In this paper, we present a content-based image retrieval method which is based on the feature extraction in the wavelet transform domain. In order to overcome the drawbacks of the feature vector making up methods which use the global wavelet coefficients in subbands, we utilize the energy value of wavelet coefficients, and the shape-based retrieval of objects is processed by moment which is invariant in translation, scaling, rotation of the objects The proposed methods reduce feature vector size, and make progress performance of classification retrieval which provides fast retrievals times. To offer the abilities of region-based image retrieval, we discussed the image segmentation method which can reduce the effect of an irregular light sources. The image segmentation method uses a region-merging, and candidate regions which are merged were selected by the energy values of high frequency bands in discrete wavelet transform. The region-based image retrieval is executed by using the segmented region information, and the images are retrieved by a color, texture, shape feature vector.

• KSCI Review
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• v.14 no.1
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• pp.265-271
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• 2006

In this paper, we propose a new automatic fingerprint identification system that identifies individuals in large databases. The algorithm consists of three steps: preprocessing, classification, and matching, in the classification, we present a new classification technique based on the statistical approach for directional image distribution. In matching, we also describe improved minutiae candidate pair extraction algorithm that is faster and more accurate than existing algorithm. In matching stage, we extract fingerprint minutiaes from its thinned image for accuracy, and introduce matching process using minutiae linking information. Introduction of linking information into the minutiae matching process is a simple but accurate way, which solves the problem of reference minutiae pair selection in comparison stage of two fingerprints quickly. This algorithm is invariant to translation and rotation of fingerprint. The proposed system was tested on 1000 fingerprint images from the semiconductor chip style scanner. Experimental results reveal false acceptance rate is decreased and genuine acceptance rate is increased than existing method.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.1
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• pp.47-54
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• 2019

Estrogen withdrawal in post-menopausal women leads to overactivation of osteoclasts, which contributes to the development of osteoporosis. Inflammatory cytokines are known as one of mechanisms of osteoclast activation after estrogen deficiency. SPA0355 is a thiourea derivative that has been investigated for its antioxidant and anti-inflammatory activities. However, its efficacy in bone resorption has not been previously investigated. The aim of this study was to investigate the impact of SPA0355 on the development of osteoporosis and to explore its mode of action. In vitro experiments showed that SPA0355 inhibited receptor activator of $NF-{\kappa}B$ ligand (RANKL)-induced osteoclastogenesis in primary bone marrow-derived macrophages. This effect appears to be independent of estrogen receptor activation as ICI 180,782 failed to abrogate its effects on osteoclasts. Further signaling studies revealed that SPA0355 suppressed activation of the MAPKs, Akt, and $NF-{\kappa}B$ pathways. SPA0355 also increased osteoblastic differentiation, as evidenced by its effects on alkaline phosphatase activity and mineralization nodule formation. Intraperitoneal administration of SPA0355 to ovariectomized mice prevented bone loss, as verified by three-dimensional images and bone morphometric parameters derived from ${\mu}CT$ analysis. Noticeably, SPA0355 did not show hepatotoxicity and nephrotoxicity and also had little effect on hematological parameters. Taken together, the results indicate that SPA0355 may protect against bone loss in ovariectomized mice by stimulation of osteoblast differentiation and by inhibition of osteoclast resorption. Therefore, SPA0355 is a safe and potential candidate for management of postmenopausal osteoporosis.

• Journal of IKEEE
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• v.23 no.2
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• pp.642-651
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• 2019

One of the most important research topics on intelligent transportation systems in recent years is detecting and recognizing a license plate. The license plate has a unique identification data on vehicle information. The existing vehicle traffic control system is based on a stop and uses a loop coil as a method of vehicle entrance/exit recognition. The method has the disadvantage of causing traffic jams and rising maintenance costs. We propose to exploit differential image of camera background instead of loop coil as an entrance/exit recognition method of vehicles. After entrance/exit recognition, we detect the candidate images of license plate using the morphological characteristics. The license plate can finally be detected using SVM(Support Vector Machine). Letter and numbers of the detected license plate are recognized using CNN(Convolutional Neural Network). The experimental results show that the proposed algorithm has a higher recognition rate than the existing license plate recognition algorithm.

• Journal of Microbiology and Biotechnology
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• v.32 no.12
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• pp.1589-1598
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• 2022

Microfibrillated cellulose (MFC) is a valuable material with wide industrial applications, particularly for the food and cosmetics industries, owing to its excellent physiochemical properties. Here, we prepared high-solid microfibrillated cellulose (HMFC) from the centrifugation of Gelidium amansiiderived MFC right after fibrillation. Dispersion properties, morphology, and structural changes were monitored during processing. HMFC has a five-fold higher solid concentration than MFC without significant changes to dispersion properties. SEM images and FTIR spectra of HMFC revealed a stable surface and structure against centrifugal forces. HMFC exhibited 2,2'-azino-bis (3-ethylbenzothiazoline6-sulfonic acid) (ABTS) radical scavenging activity, although it could not scavenge 2,2-diphenyl-1- picrylhydrazyl (DPPH). Moreover, HMFC inhibited the generation of LPS-induced excessive nitrite and radial oxygen species in murine macrophage RAW264.7 cells. Additionally, HMFC suppressed LPS-induced Keap-1 expression in the cytosol but did not alter iNOS expression. HMFC also attenuated the UVB-induced phosphorylation of p38, c-Jun N-terminal kinase (JNK) 1/2, and extracellular-signal-regulated kinase (ERK) 1/2, as well as the phosphorylation of c-Jun in the immortalized human skin keratinocyte HaCaT cells. Therefore, the application of centrifugation is suitable for producing high-solid MFC as a candidate material for anti-inflammatory and antioxidative marine cosmeceuticals.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.77-85
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• 2022

The Td05 and Sgc8c, DNA-based aptamers, are well-known to target internalized surface markers (IGHM and PTK7) of Burkitt's lymphoma and acute lymphoblastic leukemia (ALL). Thus, Td05 and Sgc8c labeled with metallic radioisotope ⁶⁴Cu can be evaluated as potential diagnostic PET imaging agents. In this study, we modified the carbon chain length of the last adenosine of aptamer (n = 3, 6, 12) to increase tumor cell uptake and select the best candidate among six types of aptamer analogues and one adenosine of aptamer. After labeling of ⁶⁴Cu, [⁶⁴Cu]Cu-DOTA-aptamer analogues were evaluated in vitro studies (serum stability, Log P values, cell uptake, biodistribution). Then, we evaluate in vivo PET imaging study for two candidates (⁶⁴Cu-DOTA-C12-Sgc8c, ⁶⁴Cu-DOTA-C6-Td05). PET images clearly visualize tumors at 24 h post-injection rather than at an early time point and the tumor-to-background ratio also increases at the delay time point. ⁶⁴Cu-DOTA-C12-Sgc8c and ⁶⁴Cu-DOTA-C6-Td05 could be used as potential radiotracers for lymphoma.