• Journal of Ginseng Research
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• v.34 no.4
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• pp.314-320
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• 2010

The previous reports have showed that ginseng saponins, which are the active ingredients of Panax ginseng, cause the relaxation of artery that are contracted due to a various of hormones or potassium ($K^+$). Recently, we also showed that ginsenosides differentially regulate channel activity. The purpose of this study was to examine whether ginseng saponins affect contraction induced by $K^+$, serotonin (5-HT), or acetylcholine (Ach) in porcine coronary vessel. Treatment with concentrations of ginseng saponins caused a relaxation of 25 mM KCl-induced porcine coronary artery contraction. Also, ginseng saponin induced a significant dose-dependent relaxation of $3\;{\mu}M$ 5-HT-induced porcine coronary artery with the endothelium. In the porcine artery with the endothelium, ginseng saponins induced a relaxation by $3\;{\mu}M$ 5-HT in a concentration-dependent pattern. Ginseng saponins induced relaxation of both 25 mM KCl- and $3\;{\mu}M$ 5-HT-induced coronary artery contraction in the absence and presence of the endothelium. In contrast, treatment with $100\;{\mu}g/mL$ ginseng saponin did not induce relaxation in coronary artery contraction induced by Ach ($0.01\;{\mu}M$ to $30\;{\mu}M$) in the presence of the endothelium, but did cause significant relaxation of coronary artery contractions by Ach ($0.01\;{\mu}M$ to $30\;{\mu}M$) in the absence of the endothelium. These findings indicate that ginseng saponin (> $100\;{\mu}g/mL$) significantly inhibits porcine coronary artery contractions caused by $K^+$, 5-HT, and Ach. Therefore, in this study, we demonstrated that ginseng saponin may show beneficial roles on abnormal coronary contraction.

• Journal of Nutrition and Health
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• v.4 no.1
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• pp.29-40
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• 1971

For the measurement on the fat content if University Students, an intensive examination was conducted on a total of 3,030 students(male 2,577, female 453), from 16 to 25 years of age. The subjects were all students who had passed the written entrance examination for Seoul National University. Total Body Fat amount was measurement by skin-fold thickness with a skin-fold caliper(Manufactured by Cambridge Scientific Industrial Inc. U.S.A.) at four sites of the body, and it was calculated by Kim's and Lee's regression equation. As a result of this survey, the following conclusions were obtained; 1. Physical Measurements: i) The average of body height by anthropometric was male $167.95{\pm}4.85cm$ and female $156.03{\pm}4.56cm$. ii) The average body weight by anthropometric was male $56.42{\pm}5.65kg$ and female $51.29{\pm}5.34kg$. iii) The average of chest-girth by anthropometric was male $89.95{\pm}5.33cm$ and female $81.36{\pm}4.89cm$. iv) The average of sitting-height by anthropometric was male $91.23{\pm}4.98cm$ and female $86.18{\pm}4.15cm$. v) The average of arm circumference by anthropometric was male $23.76{\pm}2.17cm$ and female $22.39{\pm}1.79cm$. In all cases the male measurements were higher than the female. 2. The mean skin-fold thickness measured with a large skin-fold caliper was; At the sub-scapular: male $11.54{\pm}4.84mm$ and female $14.07{\pm}4.49mm$, Abdominal: male $10.36{\pm}7.09mm$ and female $14.95{\pm}5.47mm$, Lumbar; male $12.55{\pm}6.44mm$ and female $17.02{\pm}6.57mm$, Upper arm: male $6.28{\pm}3.71mm$ and female $11.62{\pm}3.99mm$, Total average: male $10.18{\pm}5.52mm$ and female $14.41{\pm}5.13mm$, in all cases the female measurements were higher than the male. 3. Data on body fat amounts according to body fat weight regression equation were: in male: Fat weight=10.56kg, Fat free weight=45.86kg, Fat weight/Total body mass(%)=18.71%, (Body fat amount %), Fat weight/Fat free weight(%)=23.02%, Fat free weight/Total body mass(%)=81.29%. in female: Fat weight=12.23kg, Fat free weight=39.06kg, Fat weight/Total body mass(%)=23.85%, Fat weight/Fat free weight(%)=31.31%, Fat free weight/Total body mass(%)=76.15%. The females value was higher than the males.

• Journal of The Geomorphological Association of Korea
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• v.25 no.3
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• pp.1-18
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• 2018

In Korea, 64% of the land is known as mountain area, but the definition and classification standard of mountain are not clear. Demand for utilization and development of mountain area is increasing. In this situation, the unclear definition and scope of the mountain area can lead to the destruction of the mountain and the increase of disasters due to indiscreet permission of forestland use conversion. Therefore, this study analyzed the variables and criteria that can extract the mountain boundaries through the questionnaire survey and the terrain analysis. We developed a mountain boundary extraction algorithm that can classify topographic mountain by using selected variables. As a result, 72.1% of the total land was analyzed as mountain area. For the three catchment areas with different mountain area ratio, we compared the results with the existing data such as forestland map and cadastral map. We confirmed the differences in boundary and distribution of mountain. In a catchment area with predominantly mountainous area, the algorithmbased mountain classification results were judged to be wider than the mountain or forest of the two maps. On the other hand, in the basin where the non-mountainous region predominated, algorithm-based results yielded a lower mountain area ratio than the other two maps. In the two maps, we was able to confirm the distribution of fragmented mountains. However, these areas were classified as non-mountain areas in algorithm-based results. We concluded that this result occurred because of the algorithm, so it is necessary to refine and elaborate the algorithm afterward. Nevertheless, this algorithm can analyze the topographic variables and the optimal value by watershed that can distinguish the mountain area. The results of this study are significant in that the mountain boundaries were extracted considering the characteristics of different mountain topography by region. This study will help establish policies for stable mountain management.

• Journal of Science Education
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• v.38 no.2
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• pp.344-355
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• 2014

The 2009 revised curriculum emphasizes science writing as a way to foster scientific thinking, creative thinking and communicative abilities. This research attempted to find out the aspects of science writing in science textbooks by analyzing seven versions of the 2009 revised science textbooks. The results of the analysis are as follows. First, it was found that the proportion of science writing pages is small and the amount of science writing differs a lot depending on the kind of textbook. Also, science writing is generally located in the wrap-up part of each unit, and the amount and the number of science writing vary substantially from unit to unit depending on the textbook. Second, it was found that 'scientific knowledge-explanation' statements have the largest proportion and 'STS-assertion' statements have the second largest proportion in terms of topics and styles of science writing in science textbooks. Some 'scientific knowledge-explanation' statements are not appropriate to foster scientific ability because they evaluate reading comprehension of the suggested passage as nonliterary writing, not the writing itself as a method to learn science. Third, it was found that there are many predicates that do not indicate a clear purpose of the science writing contained in science textbooks.

• Journal of Korean Tunnelling and Underground Space Association
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• v.18 no.3
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• pp.257-272
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• 2016

It is usually not an easy task to counter-measure on time and appropriately when confronting with troubles in mechanized tunnelling job-sites because of the limitation of available spaces to perform those actions with the existence of disk cutter, cutter head, chamber and other various apparatus in Tunnel Boring Machine (TBM). So, it is important to predict the ground condition ahead of a tunnel face during tunnel excavation. Efforts have been made to utilize geophysical methods such as elastic wave survey, electromagnetic wave survey, electrical resistivity survey, etc for predicting the ground condition ahead of the TBM tunnel face. Each prediction method among these geophysical methods has its own advantage and disadvantage. Therefore, it might be needed to apply several geophysical methods rather than just one to predict the ground condition ahead of the tunnel face in the complex and/or mixed grounds since those methods will compensate among others. The problem is that each prediction method will give us different answer on the predicted ground condition; how to combine different solutions into a most reasonable and representative predicted value might be important. Therefore, in this study, we proposed a methodology how to systematically combine each prediction method utilizing probabilistic analysis as well as analytic hierarchy process. The proposed methods is applied to a virtual job site to confirm the applicability of the model to predict the ground condition ahead of the tunnel face in the mechanized tunnelling.

• Journal of Microbiology
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• v.40 no.3
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• pp.183-192
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• 2002

Cells infected With equine herpesvirus type-1 (EHV-1) Produced both infectious and non-infectious Virus-related particles. Compared to the whole virion, non-infectious particles termed L-particles were deter-mined to lack 150 kDa protein, commonly known as nucleocapsid protein. The potential of L-particles to induce immune responses was studied in mice and foals. Intranasal immunization with L-particles or whole virions induced poor IgG antibody responses in mice. Interestingly, despite the poor antibody response, the conferred immunity protected the host from challenge infections. This was indicated by a significant reduction in virus titers in line with recovery towards normal body weight. Subsequently, the test on the usefulness of L-particles as immunizing agents was extended to foals. Immunization of specific-pathogen-free (SPF) foals resulted in similar results. As determined by a complement-fixing-antibody test (CFT), foals seroconverted when they were immunized either with inactivated L-particles or whole virions via intramuscular (i.m.) injections. The presence of the antibody correlated with the degree of protection. Beyond day 1 post challenge infection (p.i.), there was no virus shedding in the nasal mucus of foals immunized with whole EHV-1 virions. Virus shedding was observed in foals Immunized with L-particles but limited to days 6 to 8 p.i. only. In contrast, extended vim shedding was observed in non-immunized foals and it was well beyond day 14 p.i. Viremia was not detected for more than four days except in non-immunized foals. Immunization in mice via intranasal (i.n.) conferred good protection. However, compared to the i.n. route, a greater degree of protection was obtained in foals following immunization via i.m. route. Despite variation in the degree of protection due to different routes of immunization in the two animal species, our results have established significant evidence that immunization with L-particles confers protection in the natural host. It is suggested that non-infectious L-particles should be used as immunizing agents for vaccination of horses against EHV-1 infection.

• Sleep Medicine and Psychophysiology
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• v.26 no.1
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• pp.16-22
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• 2019

Objectives: The objective of this study was to investigate the correlation between insufficient sleep and visuospatial memory in adolescents using a computerized neurocognitive function test. Methods: A total of 103 high school students (26 males and 77 females; mean age $17.11{\pm}8.50years$) without a serious psychiatric problem was recruited. All subjects were requested to complete a self-report questionnaire about weekday total sleep time and weekend total sleep time. The epworth sleepiness scale (ESS) and the beck depression inventory (BDI) were administered to measure daytime sleepiness and symptoms of depression. Seven subsets of the Cambridge Neuropsychological test automated battery were examined to assess visuospatial memory. Results: After controlling for age, sex, ESS, and BDI, longer weekend total sleep time was correlated with poor performance on delayed matching to sample (r = -0.312, p = 0.002) and immediate recall on pattern recognition memory (r = -0.225, p = 0.025). Increased weekend catch-up sleep time was correlated with poor performance of delayed matching to sample (r = -0.236, p = 0.018), immediate recall on pattern recognition memory (r = -0.220, p = 0.029), and delayed recall on pattern recognition memory (r = -0.211, p = 0.036) after controlling for age, sex, ESS, and BDI. Conclusion: This study showed that increased weekend catch-up sleep time reflecting insufficient weekday sleep were associated with poor performance in delayed recall tasks of visual memory. This finding suggests that insufficient sleep during adolescence might produce a decline of visuospatial memory.

• Journal of Korean Home Economics Education Association
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• v.35 no.4
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• pp.117-133
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• 2023

The purpose of this study is to develop and evaluate a MAKEathon programme designed to address climate change and dietary concerns, and to enhance competencies related to entrepreneurship and sustainable development. The programme was developed as a voluntary-based extracurriculum for the middle and high school students in South Korea. In order to verify the effectiveness, surveys were conducted before and after the program, focusing on the measures of the three competencies i.e. sustainable development competencies, creativity, and entrepreneurship, as well as the programme satisfaction and demographic background. Paired t-tests of pre-/post-tests were conducted on the responses of 29 participants and the results indicate significant improvement in the three competencies and high programme satisfaction. These findings underscore the value of incorporating extracurricular programmes related to sustainability in home economics education, suggesting potential for broader application in topics like clothing, food, and housing. Such programmes are poised to enhance educational effectiveness in teaching problem-solving for sustainable development.

• Korean journal of applied entomology
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• v.56 no.2
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• pp.213-222
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• 2017

Among flies inside mushroom growing rooms in three farms, Lycoriella ingenua and Megaselia tamilnaduensis were the most common and dominant species during Pleurotus ostreatus cultivation in Korea. In the past, generally, during the incubation period, a low density of mushroom flies was observed in all farms. After the first harvest, mushroom flies density tended to increase sharply. However, many mushroom flies were observed in the summer, despite that season corresponds to the incubation period. This is because annual cultivation systems provide a safe overwintering place compared to seasonal selective ones. The ecology of mushroom flies varies greatly according to the cultivation system. We confirmed that a fallow period reduced the density of mushroom flies. From a survey of the three dimensional distribution of mushroom flies in a growing room, we observed that M. tamilnaduensis showed more positive phototaxis and a higher variation per point of capture than that by L. ingenua. Through this study, two mushroom fly species were identified in the survey farms, with markedly different three dimensional distribution patterns.

• Journal of the Korean Chemical Society
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• v.63 no.4
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• pp.289-306
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• 2019

The purpose of this study is to compare the contents of chemistry textbooks developed according to the 2015 revised curriculum with the contents of the 2009 revised curriculum to research the change in "the development and use of models". To do this, we analyzed 8 kinds of Chemistry I textbooks and 6 kinds of Chemistry II textbooks from the 2015 revised curriculum and compared them with 4 kinds of Chemistry I textbooks and 4 kinds of Chemistry II textbooks from the 2009 revised curriculum. The scope of the analysis was the explanations of the textbooks related to aqueous electrolysis experiments. In order to compare the contents regarding electrolytes when the same experiments are interpreted with different models, we analyzed contents of 4 kinds of middle school science textbooks from the 2015 revised curriculum and 9 kinds of middle school science textbooks from the 2009 revised curriculum. As a result of the analysis, the same experiment was explained by different models according to the grade level and unit, and all explanations were limited to a single model. Also, the tendency to limit the kinds of electrolytes for controlled experimental results is more pronounced in the 2015 revised curriculum than in the 2009 revised curriculum. From this results, we suggest that efforts are needed to reflect the "development and use of models" in chemistry textbooks developed according to the 2015 revised curriculum.