• 대한방사선기술학회지:방사선기술과학
• /
• 제45권6호
• /
• pp.553-560
• /
• 2022

The purpose of this study is to evaluate the clinical risk according to the applicator heterogeneity, mislocation, and tissue heterogeneity correction through a dose verification program during brachytherapy of cervical cancer. We performed image processing with MATLAB on images acquired with CT simulator. The source was modeled and stochiometric calibration and Monte-Carlo algorithm were applied based on dwell time and location to calculate the dose, and the secondary cancer risk was evaluated in the dose verification program. The result calculated by correcting for applicator and tissue heterogeneity showed a maximum dose of about 25% higher. In the bladder, the difference in excess absolute risk according to the heterogeneity correction was not significant. In the rectum, the difference in excess absolute risk was lower than that calculated by correcting applicator and tissue heterogeneity compared to the water-based calculation. In the femur, the water-based calculation result was the lowest, and the result calculated by correcting the applicator and tissue heterogeneity was 10% higher. A maximum of 14% dose difference occurred when the applicator mislocation was 20 mm in the Z-axis. In a future study, it is expected that a system that can independently verify the treatment plan can be developed by automating the interface between the treatment planning system and the dose verification program.

• 한국수자원학회:학술대회논문집
• /
• 한국수자원학회 2021년도 학술발표회
• /
• pp.268-268
• /
• 2021

Groundwater resource is mostly used in Abomey-calavi (southern region of Benin) as main source of water for domestic, industrial, and agricultural activities. Groundwater intake across the region is not perfectly controlled by a network due to the presence of many private boreholes and traditional wells used by the population. After some decades, this important resource is becoming more and more vulnerable and needs more attention. For a better groundwater management in the region of Abomey-calavi, the present study attempts to predict a future probable groundwater drought using Recurrent Neural Network (RNN) for future groundwater level prediction. The RNN model was created in python using jupyter library. Six years monthly groundwater level data was used for the model calibration, two years data for the model test and the model was finaly used to predict two years future groundwater level (years 2020 and 2021). GRI was calculated for 9 wells across the area from 2012 to 2021. The GRI value in dry season (by the end of March) showed groundwater drought for the first time during the study period in 2014 as severe and moderate; from 2015 to 2021 it shows only moderate drought. The rainy season in years 2020 and 2021 is relatively wet and near normal. GRI showed no drought in rainy season during the study period but an important diminution of groundwater level between 2012 and 2021. The Pearson's correlation coefficient calculated between GRI and rainfall from 2005 to 2020 (using only three wells with times series long period data) proved that the groundwater drought mostly observed in dry season is not mainly caused by rainfall scarcity (correlation values between -0.113 and -0.083), but this could be the consequence of an overexploitation of the resource which caused the important spatial and temporal diminution observed from 2012 to 2021.

• 한국산업보건학회지
• /
• 제33권4호
• /
• pp.439-446
• /
• 2023

Objectives: The aims of this study are to investigate how X-rays are emitted to surrounding parts during the ion implantation process, to analyze these emissions in relation to the properties of the ion implanter equipment, and to estimate the resulting exposure dose. Eight ion implanters equipped with high-voltage electrical systems were selected for this study. Methods: We monitored X-ray emissions at three locations outside of the ion implanters: the accelerator equipped with a high-voltage energy generator, the impurity ion source, and the beam line. We used a Personal Portable Dose Rate and Survey Meter to monitor real-time X-ray levels. The SX-2R probe, an X-ray Features probe designed for use with the Radiagem^TM meter, was also utilized to monitor lower ranges of X-ray emissions. The counts per second (CPS) measured by the meter were estimated and then converted to a radiation dose (𝜇Sv/hr) based on a validated calibration graph between CPS and μGy/hr. Results: X-rays from seven ion implanters were consistently detected in high-voltage accelerator gaps, regardless of their proximity. X-rays specifically emanated from three ion implanters situated in the ion box gap and were also found in the beam lines of two ion implanters. The intensity of these X-rays did not show a clear pattern relative to the devices' age and electric properties, and notably, it decreased as the distance from the device increased. Conclusions: In conclusion, every gap, in which three components of the ion implanter devices were divided, was found to be insufficiently shielded against X-ray emissions, even though the exposure levels were not estimated to be higher than the threshold.

• 한국근적외분광분석학회:학술대회논문집
• /
• 한국근적외분광분석학회 2001년도 NIR-2001
• /
• pp.3104-3104
• /
• 2001

The research described here was undertaken with the aim of monitoring, optimizing and ultimately controlling the production of heterofermentative microbes used as starters in the salami industry. The use of starter cultures in the fermented meats industry is a well-established technique used to shorten and standardize the ripening process, and to improve and control the organoleptic quality of the final product. Starter cultures are obtained by the submerged cultivation of suitable microorganisms in stirred, and sometimes aerated, fermenters where monitoring of key physiological parameters such as the concentration of biomass, substrates and metabolites suffers from the general lack of real-time measurement techniques applicable to aseptic processes. In this respect, the results of the present work are relevant to all submerged fermentation processes. Previous work on the application of on-line NIR spectroscopy to the lactic acid fermentation (Dosi et al. - Monreal NIR1995) had successfully used a system based on a measuring cell included in a circulation loop external to the fermenter. The fluid handling and sterility problems inherent in an external circulation system prompted us to explore the use of an in-line system where the NIR probe is immersed in the culture and is thus exposed to the hydrodynamic conditions of the stirred and aerated fluid. Aeration was expected to be a potential source of problems in view of the possible interference of air bubbles with the measurement device. The experimental set-up was based on an in-situ sterilizable NIR probe connected to the instrument by means of an optical fiber bundle. Preliminary work was carried out to identify and control potential interferences with the measurement, in particular the varying hydrodynamic conditions prevailing at the probe tip. We were successful in defining the operating conditions of the fermenter and the geometrical parameters of the probe (flow path, positioning, etc.) were the NIR readings were reliable and reproducible. The system thus defined was then used to construct and validate calibration curves for tile concentration of biomass, carbon source and major metabolites of two different microorganisms used as salami starters. Real-time measurement of such parameters coupled with the direct interfacing of the NIR instrument with the PC-based measurement and control system of the fermenter enabled the development of automated strategies for the interactive optimization of the starter production process.

• 분석과학
• /
• 제14권3호
• /
• pp.230-237
• /
• 2001

일반적인 pH의 측정은 유리전극을 사용한 pH 측정기를 pH 표준용액으로 검정한 다음, 시료용액의 pH를 측정하는 절차를 따른다. 일정 온도의 pH 측정에서 불확도에 영향을 미치는 인자는 pH 표준용액의 불확도와 유리전극의 정확도 및 재현성이라 할 수 있다. 본 연구에서는 실제로 동일한 시료에 대해 각 실험실에서 측정하고 있는 pH 측정값이 어떠한 분포를 보이며, 오차 발생 시 주된 요인이 무엇인지를 알기 위해 pH 표준용액 시료를 사용하여 자원하는 국내의 실험실을 대상으로 98, 99년에 걸쳐 숙련도 시험을 실시하였다. 숙련도 시험 시료는 $25^{\circ}C$에서 pH 6.860, 7.415의 값을 가지는 인산염 표준용액을 제조하여 사용하였고, 숙련도 시험 기간내의 안정도 여부를 확인하기 위해 안정도 시험을 실시하였다. 숙련도 시험 결과를 Youden plot하여 측정 결과의 오차가 우연효과에 의한 것인지 계통효과에 의한 것인지를 파악하였을 때, 두 해 모두 오차를 갖는 실험실들이 계통효과에 의한 오차만을 나타내었다. 이는 각 실험실에서 사용하고 있는 표준용액이 오차의 원인임을 말해 주고 있다.

• 한국환경농학회지
• /
• 제20권3호
• /
• pp.192-200
• /
• 2001

우리 나라의 농업지대 소유역에서 질소와 인의 부하에 대한 농업비점오염 모형 AGNPS의 적용 가능성을 검토하고자 경북 영천군 임고천 유역에서 조사된 실제 강우사상에 대하여 강우사상별로 실측치와 모형의 예측치를 비교하였다. CN 식에 대한 보정을 거친 모형을 적용한 결과, 첨두유량은 강우에 따라 다소 차이는 있었으나 예측치는 모형효율 0.97로 실측치와 거의 일치하였다. 이는 유역의 특성을 고려하여 CN 식을 수정하였고 유역의 동질성을 위해 격자망을 비교적 세분화하였기 때문으로 판단된다. 총 질소와 총인 농도의 경우의 실측치와 예측치를 비교하면 모형효율은 각각 0.93과 0.74였으며, 총인의 경우 총질소에 비해 결정계수가 비교적 낮은 것은 토지 이용에 따른 시비 및 생활 및 축산 오수 유입 등의 차이에 상대적으로 민감하게 영향을 받았기 때문으로 판단된다. 농업비점오염 부하를 예측하는 모형인 AGNPS는 적용 대상 유역의 특성을 잘 고려하여 매개변수들을 적절히 보정하고 정확한 입력자료를 확보하면 우리 나라 소규모 농업 유역에서도 활용될 수 있을 것으로 판단된다.

• Journal of Radiation Protection and Research
• /
• 제41권4호
• /
• pp.395-401
• /
• 2016

Background: Liquid scintillation counters (LSCs) are commonly used as an analytical method for detecting $^{222}Rn$ in groundwater because they involve a simple sample pretreatment and allow high throughout with an autosampler. The Quantulus 1220 is the best-selling LSC in Korea, but its production was stopped. Recently, a new type of LSC, the 300SL, was introduced. In this study, the 300SL was compared with the Quantulus 1220 in order to evaluate the ability of each apparatus to detect $^{222}Rn$ in groundwater. Materials and Methods: The Quantulus 1220 and 300SL were used to detect the presence of $^{222}Rn$. Radon gas was extracted from a groundwater sample using a water-immiscible cocktail in a LSC vial. The optimal analytical conditions for each LSC were determined using a $^{222}Rn$ calibration source prepared with a $^{226}Ra$ source. Results and Discussion: The optimal pulse shape analysis level for alpha and beta separation was 80 for the Quantulus 1220, and the corresponding pulse length index was 12 in the 300SL. The counting efficiency of the Quantulus 1220 for alpha emissions was similar to that of the 300SL, but the background count rate of the Quantulus 1220 was 10 times lower than that of the 300SL. The minimum detectable activity of the Quantulus 1220 was $0.08Bq{\cdot}L^{-1}$, while that of the 300SL was $0.20Bq{\cdot}L^{-1}$. The analytical results regarding $^{222}Rn$ in groundwater were less than 10% different between these LSCs. Conclusion: The 300SL is an LSC that is comparable to the Quantulus 1220 for detecting $^{222}Rn$ in groundwater. Both LSCs can be applied to determine the levels of $^{222}Rn$ in groundwater under the management of the Ministry of Environment.

• Restorative Dentistry and Endodontics
• /
• 제36권2호
• /
• pp.98-107
• /
• 2011

치아우식증은 현대 사회에서 여전히 유병률이 높으며, 치과 분야의 주요 상병으로 자리잡고 있다. 치아우식증에 대한 연구에 매우 다양한 방법들이 동원되고 있으나, 최근 미세전산화 단층촬영은 비파괴적인 3차원 분석 기술로서 인기를 얻어 왔으며, 기존의 방법들에 비해 다양한 장점들을 가지고 있다. 미세전산화 단층촬영술은 X선원의 종류에 따라, 모노크로매틱 혹은 폴리크로매틱으로 나뉘어지고, 전자의 경우 몇몇 장점에도 불구하고, 고가의 장비를 요구하므로 후자가 훨씬 널리 사용된다. 투과방사선량의 감소에 따라 결정되는 미네랄 밀도의 차이가 기본 원리이며, 보다 좋은 이미지와 재현 가능한 측정을 위해서는 장비의 교정과 이미지 보정 작업등이 요구된다. 또한, 미세전산화 단층촬영술을 이용하면, 치아우식 병소의 3차원적인 재건이 가능하며, 병소의 내부 구조를 가시화할 수 있다. 최근 컴퓨터 기술의 발전과 더불어 다양한 응용이 시도되고 있는데, 자동화된 충치의 정량적 분석 알고리즘 등이 그 예에 해당된다.

• 핵의학기술
• /
• 제22권2호
• /
• pp.105-111
• /
• 2018

Purpose Quality control of instrument takes up a large part in the Radioimmunoassays. The gamma-ray instrument, which is one of the important instruments in the laboratory, observes the condition and performance of instrument and performs quality control of the instrument by measuring the Normalization, Calibration, Background and etc. However, there are some automation instruments which can't measure the counting efficiency of gamma-ray meters, resulting in insufficient management in terms of performance evaluation of gamma-ray meters. Therefore, the purpose of this paper is to manage the quality control continuously and regularly by suggesting how to measure the counting efficiency of gamma-ray instruments. Materials and Methods In case of a comparative measurement method to a gamma-ray instrument dedicated to nuclear medical examination, the CPM and counting efficiency can be obtained after the measurement of normalization by inserting the I-125 $200{\mu}L$(CPM 50,000~500,000) into the test tube. With this CPM and counting efficiency values, it's possible to calculate the measurement of the DPM value and count the CPM from the automation instrument from the same source, and enter the DPM to calculate the counting efficiency using a comparative measurement method. Another method is to calculate the counting efficiency by estimating the half life using the radiation source information of the tracer in B test reagents of company A. Results According to the calculation formula using the DPM obtained by counting the normalization of gamma-ray meters, the detection efficiency was 75.16% for Detector 1, 76.88% for Detector 2, 77.13% for Detector 3, 75.36% for Detector 4 and 73.2% for Detector 5 respectively. Using another calculation formula estimated from the shelf life, the data of the detection efficiency from Detector 1 to Detector 5 were 74.9%, 75.1%, 76.5%, 74.9% and 73.2% respectively. Conclusion Although the accuracy of counting efficiencies of both methods are insufficient, this is considered to be useful for ongoing management of quality control if counting efficiency is managed after setting the acceptable ranges. For example, if the measurement efficiency is set to 70% or higher, the allowed %difference between measurements is within 3% and the %difference with the detector wall is set within 5%.

• 대한토목학회논문집
• /
• 제28권6B호
• /
• pp.653-663
• /
• 2008

본 연구에서는 안성천 공도수위관측소 상류유역을 대상으로 SWAT(Soil and Water Assessment Tool) 모형을 이용하여 현재의 유역 수문환경조건을 보다 현실적으로 분석하기 위해서 기상, 수문 자료와 점오염원 운영자료, 저수지의 방류량 자료 및 경작관리 형태의 자료를 구축하여 후속연구인 "미래 기후변화 및 토지이용 변화에 따른 안성천 유역 수문-수질 변화 분석 (II)"의 기본 자료로 활용하는데 목적이 있다. 유역 현실에 보다 가까운 분석을 위해 유역특성 자료인 점오염원 운영자료, 저수지의 방류량 자료 및 경작관리 형태의 자료를 구축, 분석한 후 모형의 검 보정을 실시하였다. 유역 특성 자료에 따른 분석 결과, 경작관리의 경우 농경지로 인한 수질 부하량의 경향과 흐름이 바뀌게 되며, 저수지 적용자료 적용시는 4-5월 시기의 관개를 위하여 방류를 시도한 패턴을 확인 할 수 있었다. 또한 환경기초시설, 경작관리를 미적용 및 적용시 약 10%의 하천수질 모의결과 차이가 발생하기 때문에 유역의 실제적인 상황에 근접하게 적용하기 위해서는 대상유역내의 정확한 자료의 구축과 적용이 중요하다고 판단되며, 유역 특성 자료를 통한 검보정 결과는 (II) 연구에서 기후변화와 토지이용에 따른 유역 수문-수질 변화 분석에 활용되어 보다 신뢰도 높은 결과를 도출 할 수 있을 것으로 판단된다.