• Title/Summary/Keyword: Calibration process

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Determination of Ceftiofur Residues by Simple Solid Phase Extraction Coupled with Liquid Chromatography-Tandem Mass Spectrometry in Eel, Flatfish, and Shrimp

  • Kim, Joohye;Shin, Dasom;Kang, Hui-Seung;Lee, Eunhye;Choi, Soo Yeon;Lee, Hee-Seok;Cho, Byung-Hoon;Lee, Kang-Bong;Jeong, Jiyoon
    • Mass Spectrometry Letters
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    • v.10 no.2
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    • pp.43-49
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    • 2019
  • The aim of this study was conducted to develop an analytical method to determine the concentration of ceftiofur residue in eel, flatfish, and shrimp. For derivatization and extraction, the sample was hydrolyzed with dithioerythritol to produce desfuroylceftiofur, which was then derivatized by iodoacetamide to obtain desfuroylceftiofur acetamide. For purification, the process of solid phase extraction (Oasis HLB) was used. The target analytes were confirmed and quantified in $C_{18}$ column using liquid chromatography-tandem mass spectrometry with 0.1% formic acid in water (A) and 0.1% formic acid in acetonitrile (B) as the mobile phase. The linearity of the standard calibration curve was confirmed by a correlation coefficient, $r^2>0.99$. The limit of quantification for ceftiofur was 0.002 mg/kg; the accuracy (expressed as the average recoveries) was 80.6-105%; the precision (expressed as the coefficient of variation) was below 6.3% at 0.015, 0.03, and 0.06 mg/kg. The validated method demonstrated high accuracy and acceptable sensitivity to meet the Codex guideline requirements. The developed method was tested using market samples. As a results, ceftiofur was detected in one sample. Therefore, it can be applied to the analysis of ceftiofur residues in fishery products.

Start Point Detection Method for Tracing the Injection Path of Steel Rebars (철근 사출 궤적 추적을 위한 시작지점 검출 방법)

  • Lee, Jun-Mock;Kang, Dae-Seong
    • The Journal of Korean Institute of Information Technology
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    • v.17 no.6
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    • pp.9-16
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    • 2019
  • Companies that want to improve their manufacturing processes have recently introduced the smart factory, which is particularly noticeable. The ultimate goal is to maximize the area of the smart factory that performs the process of the production facility completely with minimal manual control and to minimize errors of reasoning. This research is a part of a project for unmanned production, management, packaging, and delivery management and the detection of the start point of rebars to perform the automatic calibration of the rollers through the tracking of the automated facilities of unmanned production. It must meet the requirement to accurately track the position from the start point to the end point. In order to improve the tracking performance, it is important to set the accurate start point. However, the probability of tracking errors is high depending on environments such as illumination and dust through the conventional time-based detection method. In this paper, we propose a starting point detection method using the average brightness change of high speed IR camera to reduce the errors according to the environments, As a result, its performance is improved by more than 15%.

A Study on the Construction of MVCT Dose Calculation Model by Using Dosimetry Check™ (Dosimetry Check™를 이용한 MVCT 선량계산 모델 구축에 관한 연구)

  • Um, Ki-Cheon;Kim, Chang-Hwan;Jeon, Soo-Dong;Back, Geum-Mun
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.431-441
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    • 2020
  • The purpose of this study was to construct a model of MVCT(Megavoltage Computed Tomography) dose calculation by using Dosimetry Check™, a program that radiation treatment dose verification, and establish a protocol that can be accumulated to the radiation treatment dose distribution. We acquired sinogram of MVCT after air scan in Fine, Normal, Coarse mode. Dosimetry Check™(DC) program can analyze only DICOM(Digital Imaging Communications in Medicine) format, however acquired sinogram is dat format. Thus, we made MVCT RC-DICOM format by using acquired sinogram. In addition, we made MVCT RP-DICOM by using principle of generating MLC(Multi-leaf Collimator) control points at half location of pitch in treatment RP-DICOM. The MVCT imaging dose in fine mode was measured by using ionization chamber, and normalized to the MVCT dose calculation model, the MVCT imaging dose of Normal, Coarse mode was calculated by using DC program. As a results, 2.08 cGy was measured by using ionization chamber in Fine mode and normalized based on the measured dose in DC program. After normalization, the result of MVCT dose calculation in Normal, Coarse mode, each mode was calculated 0.957, 0.621 cGy. Finally, the dose resulting from the process for acquisition of MVCT can be accumulated to the treatment dose distribution for dose evaluation. It is believed that this could be contribute clinically to a more realistic dose evaluation. From now on, it is considered that it will be able to provide more accurate and realistic dose information in radiation therapy planning evaluation by using Tomotherapy.

Current Status of Application of KOMPSAT Series (최근 다목적실용위성 시리즈 활용 현황)

  • Lee, Kwang-Jae;Oh, Kwan-Young;Lee, Won-Jin
    • Korean Journal of Remote Sensing
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    • v.36 no.6_2
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    • pp.1485-1492
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    • 2020
  • It has been more than 20 years since the launch of KOMPSAT-1, and so far, a total of 5 satellites have been successfully launched. Until now, KOMPSAT has been used in various fields, including the production of various thematic maps, land change, environmental analysis, and marine monitoring. Many researchers have conducted research to process, analyze, and utilize KOMPSAT images. According to the national space development plan, the KOMPSAT series will be continuously developed to meet the demand for satellite images at the national level. If the ultimate purpose of satellite development is to utilize acquired images, systematic research to effectively utilize the developed satellites should be followed. This special issue introduces the recently conducted research on the use of KOMPSAT images.

Methodology of Correcting Barometer Using Moving Drone and RTK Receiver (동적 드론과 RTK 수신기를 이용한 기압계 보정정보 생성 방법론)

  • Kim, Suyeol;Yun, Jeonghyeon;Park, Byungwoon
    • Journal of Advanced Navigation Technology
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    • v.26 no.2
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    • pp.63-71
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    • 2022
  • Barometers have been used to calculate altitude, and with the development of technology, barometer which had a large volume have now been reduced to about centimeter-level. The altitude calculation using barometer is proceeded using the relationship between reference sea level pressure and the pressure obtained by barometer, and for this, pre-calibration of the barometer is essential. In addition, the barometer has a certain level of bias from actual pressure due to production, and many smartphone manufacturers correct it during the manufacturing process, but it is difficult to correct errors caused by environmental variables. In this paper, we extended methodology of correcting barometer using static reference station to moving drone, and it was possible to calculate the altitude more accurately.

Surface Modification of Gold Electrode Using Nafion Polymer and Its Application as an Impedance Sensor for Measuring Osmotic Pressure (나피온 폴리머를 이용한 금 전극의 표면 개질 및 이의 삼투압 측정용 임피던스 센서 응용)

  • Min Sik, Kil;Min Jae, Kim;Jo Hee, Yoon;Jinwu, Jang;Kyoung G., Lee;Bong Gill, Choi
    • Applied Chemistry for Engineering
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    • v.34 no.1
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    • pp.9-14
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    • 2023
  • In this work, we developed a Nafion polymer-coated impedance sensor with two gold electrode configurations to measure the ion concentration in solution samples. The gold electrodes were fabricated through the sputtering process, followed by surface modification using Nafion polymer. The resulting sensors enable the prevention of the polarization phenomenon on the electrode surface, resulting in stable measurement of electrochemical signals. Spectroscopy and scanning electron microscopy measurements revealed that the thin film of Nafion was coated uniformly onto the surface of the gold electrode. The Nafion-coated sensor exhibited more stable impedance signals than the conventional gold electrode. It showed a highly reliable calibration curve (R2 = 0.983) of the impedance sensor using a standard sodium chloride solution. In addition, a comparison experiment between the impedance sensor and a commercial conductivity sensor was performed to measure the ion concentration of artificial tears, showing similar results for the two sensors.

Calibration of cylindrical NaI(Tl) gamma-ray detector intended for truncated conical radioactive source

  • Badawi, Mohamed S.;Thabet, Abouzeid A.
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1421-1430
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    • 2022
  • The computation of the solid angle and the detector efficiency is considering to be one of the most important factors during the measuring process for the radioactivity, especially the cylindrical γ-ray NaI(Tl) detectors nowadays have applications in several fields such as industry, hazardous for health, the gamma-ray radiation detectors grow to be the main essential instruments in radiation protection sector. In the present work, a generic numerical simulation method (NSM) for calculating the efficiency of the γ-ray spectrometry setup is established. The formulas are suitable for any type of source-to-detector shape and can be valuable to determine the full-energy peak and the total efficiencies and P/T ratio of cylindrical γ-ray NaI(Tl) detector setup concerning the truncated conical radioactive source. This methodology is based on estimate the path length of γ-ray radiation inside the detector active medium, inside the source itself, and the self-attenuation correction factors, which typically use to correct the sample attenuation of the original geometry source. The calculations can be completed in general by using extra reasonable and complicate analytical and numerical techniques than the standard models; especially the effective solid angle, and the detector efficiency have to be calculated in case of the truncated conical radioactive source studied condition. Moreover, the (NSM) can be used for the straight calculations of the γ-ray detector efficiency after the computation of improvement that need in the case of γ-γ coincidence summing (CS). The (NSM) confirmation of the development created by the efficiency transfer method has been achieved by comparing the results of the measuring truncated conical radioactive source with certified nuclide activities with the γ-ray NaI(Tl) detector, and a good agreement was obtained after corrections of (CS). The methodology can be unlimited to find the theoretical efficiencies and modifications equivalent to any geometry by essential sufficiently the physical selective considered situation.

Monitoring of heavy metals, bisphenol A and phenol migrated from food packages for delivery

  • Cho, Hyunnho;Yun, Ho Cheol;Lee, Ji Yoon;Kwon, Hyeon Jeong;Jeong, Eun Jung;Kim, Da Young;Lee, Seong Ju;Kang, Jung Mi
    • Analytical Science and Technology
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    • v.35 no.1
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    • pp.15-23
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    • 2022
  • Food delivery is gaining popularity due to changes in lifestyle and dietary patterns. However, packages used to delivery food may contain contaminants including heavy metals, or additives added during manufacturing process which may migrate into food during processing and transportation. In this study, a total of 58 food packages for delivery were collected and tested for migration of heavy metals (lead, cadmium and arsenic), bisphenol A and phenol into food simulants. The method was validated by evaluating linearity of calibration curve, limit of detection, limit of quantification, recovery and precision. Result of heavy metal migration showed that lead was the most frequently migrated metal and the highest concentration was detected in a polypropylene sample. Although there are no specific migration limits for bisphenol A and phenol in packaging materials tested in this study, migrations of bisphenol A and phenol were detected in some packages. This may due to contamination or additives added during manufacture of packages. Risk (%) was calculated to analyze the risk associated with the migration of heavy metals, bisphenol A and phenol, and was always below 1 %. These results showed that food packages for delivery are safe in terms of heavy metals, bisphenol A and phenol migration.

Design and Fabrication of Rogowski-type Partial Discharge Sensor for Insulation Diagnosis of Cast-Resin Transformers (몰드 변압기의 절연 진단을 위한 로고우스키형 부분방전 센서의 설계 및 제작)

  • Lee, Gyeong-Yeol;Kim, Sung-Wook;Kil, Gyung-Suk
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.6
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    • pp.594-602
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    • 2022
  • Cast-resin transformers are widely installed in various electrical power systems because of their low operating cost and low influence on external environmental factors. However, when they have an internal defect during the manufacturing process or operation, a partial discharge (PD) occurs, and eventually destroys the insulation. In this paper, a Rogowski-type PD sensor was studied to replace commercial PD sensors used for the insulation diagnosis of power apparatus. The proposed PD sensor was manufactured with four different types of PCB-based winding structures, and it was analyzed in terms of the detection characteristics for standard calibration pulses and the changes of the output voltage according to the distance. The output increased linearly in accordance with the applied discharge amount. It was confirmed that the hexagon structure sensor had the highest sensitivity, because the winding cross-sectional area of the sensor was larger than others. In addition, as the distance from the defect increased, the output voltage of the sensors decreased by 7.32% on average. It was also confirmed that the attenuation rate according to the distance decreased as the input discharge amount increased. For the application of this new type sensor, PD electrode system was designed to simulate the void defect. Waveforms and PRPD patterns measured by the proposed PD sensors at DIV and 120% of DIV were the same as the results measured by MPD 600 based on IEC 60270. The proposed PD sensors can be installed on the inner wall of the transformer tank by coating its surfaces with a non-conductive material; therefore, it is possible to detect internal defects more effectively at a closer distance from the defect than the conventional sensors.

A Study on Predictive Modeling of I-131 Radioactivity Based on Machine Learning (머신러닝 기반 고용량 I-131의 용량 예측 모델에 관한 연구)

  • Yeon-Wook You;Chung-Wun Lee;Jung-Soo Kim
    • Journal of radiological science and technology
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    • v.46 no.2
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    • pp.131-139
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    • 2023
  • High-dose I-131 used for the treatment of thyroid cancer causes localized exposure among radiology technologists handling it. There is a delay between the calibration date and when the dose of I-131 is administered to a patient. Therefore, it is necessary to directly measure the radioactivity of the administered dose using a dose calibrator. In this study, we attempted to apply machine learning modeling to measured external dose rates from shielded I-131 in order to predict their radioactivity. External dose rates were measured at 1 m, 0.3 m, and 0.1 m distances from a shielded container with the I-131, with a total of 868 sets of measurements taken. For the modeling process, we utilized the hold-out method to partition the data with a 7:3 ratio (609 for the training set:259 for the test set). For the machine learning algorithms, we chose linear regression, decision tree, random forest and XGBoost. To evaluate the models, we calculated root mean square error (RMSE), mean square error (MSE), and mean absolute error (MAE) to evaluate accuracy and R2 to evaluate explanatory power. Evaluation results are as follows. Linear regression (RMSE 268.15, MSE 71901.87, MAE 231.68, R2 0.92), decision tree (RMSE 108.89, MSE 11856.92, MAE 19.24, R2 0.99), random forest (RMSE 8.89, MSE 79.10, MAE 6.55, R2 0.99), XGBoost (RMSE 10.21, MSE 104.22, MAE 7.68, R2 0.99). The random forest model achieved the highest predictive ability. Improving the model's performance in the future is expected to contribute to lowering exposure among radiology technologists.