• Title/Summary/Keyword: Ca addition

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Vasodilatory Effects of Samhwangsasim-tang on Vascular Smooth Muscle (삼황사심탕의 혈관이완 효능과 기전)

  • Kim Jong Bong;Kwon Oh Kui;Son Chang Woo;Shin Heung Mook
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.5
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    • pp.1382-1386
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    • 2004
  • This study was performed for the investigation of vasodilatory efficacy and its underlying mechanisms of Samhwangsasim-tang(SST), herbal remedy. SST relaxed vascular strips precontracted with phenylephrine or KCI(51 mM), but the magnitude of relaxation was greater in phenylephrine(PE) induced contraction. The relaxation effects of SST was endothelium-independent. L-NAME, iNOS inhibitor, and methyl en blue(MB), cGMP inhibitor, did not attenuate the relaxation responses of SST. In the absence of extracellular Ca2+, pre-incubation of the aortic rings with SST significantly reduced the contraction by PE, suggesting that the relaxant action of the SST includes inhibition of Ca/sup 2+/ influx and release of Ca/sup 2+/ from intracellular stores (SR). In addition, the cell death was induced by SST in human aortic smooth muscle cells but not that of human umbilical vein endothelial cells. We conclude that in rat thoracic aorta, SST may induce in part vasodilation through inhibition of Ca/sup 2+/ influx and release of Ca/sup 2+/ from intracellular stores.

Phorbol Ester-Induced Periodic Contraction in Isolated Rabbit Jugular Vein

  • Ryu, Jae-Cheol;Jung, Dong-Keun;Lee, Sang-Ho
    • The Korean Journal of Physiology
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    • v.29 no.2
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    • pp.225-232
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    • 1995
  • The present study was conducted to evaluate the effect of phorbol 12,13-dibutyrate (PDBu) on the contraction of rabbit jugular vein in vitro. PDBu concentrations of greater than 10 nM induced a periodic contraction which was composed of rapid contraction, plateau and slow relaxation. The frequency of periodic contraction increased as PDBu concentration increased. The PDBu-induced contraction was inhibited by staurosporine (100 nM), it was not changed by tetrodotoxin $(1\;{\mu}M).$ In $Ca^{2+}$-free medium, PDBu induced a sustaining contraction, but not periodic contraction. Addition of $Ca^{2+}$ to medium evoked periodic contraction which was inhibited by nifedipine, PDBu concentrations of greater than $0.1\;{\mu}M$ increased ^{45}Ca^{2+}$ uptake without changing $^{45}Ca^{2+}$ efflux. Charybdotoxin and apamin, $Ca^{2+}$-activated K^{+}$ channel blockers, did not affect the PDBu-induced periodic contraction, whereas tetraethylammonium (TEA) abolished the periodicity. Pinacidil $(10\;{\mu}M).$, a potassium channel activator, blocked PDBu induced periodic contraction, which was recovered by glybenclamide $(10\;{\mu}M).$. In high potassium solution, PDBu did not produce the periodic contraction. These results suggest that the PDBu-induced periodicity of contraction is modulated by voltage dependent $Ca^{2+}$ channel and ATP-sensitive $K^{+}$ channel.

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Nitro oxide in human cytomegalovirus replication and gene expression

  • Lee, Jee-Yeon;Lee, Chan-Hee
    • Journal of Microbiology
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    • v.35 no.2
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    • pp.152-157
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    • 1997
  • Infection of human fibroblast (HF) cells with human cytomegalovirus (HCMV) result in changes in the intracellular level of second messengers. Since nitric oxide (NO) production has been known to be related with other second messengers, it is probable that HCMV infection of HF cells may involve NO. To test this possibility, the amount of NO was measured following ogenous addition of NO generators such as sodium nitroprusside (SNP) or S-nitroso-N-a-cetylpenicillamine (SNAP) immediately after HCMV infection, however, inhibited virus multiplication. Furthermore, immunoblot experiment using monoclonal antibody to HCMV major immediate early (MIE) proteins or CAT assay using pCMVIE/CAT (plasmid containing CAT gene driven by HCMV MIE promoter) revealed that SNP or SNAP blocked the MIE gene expression. SNP was more effective than SNAP in hibiting HCMV multiplication or MIE gene expression. SNP produced more NO than SNAP in inhibiting HCMV multiplication or MIE gene expression. SNP produced more NO than SNAP. Although the mechanism for the inhibition of HCMV multiplication and MIE gene expression by NO is still elusive some correlation with NO-mediated inhibition of HCMV-induced increase in cytosolic free Ca$\^$2+/ concentration ([Ca$\^$2+/]) was observed. The increase of [Ca$\^$2+/] following HCMV infection was inhibited by SNP, and less effectively by SNAP. Raising [Ca$\^$2+/ with bromo-A23187 partially reversed the SNP block of MIE gene expression. Thus, there appear to e some relationships among NO. [Ca$\^$2+/], and HCMV MIE gene expression.

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Effect of Pb($Fe_{2/3}W_{1/3}$)$O_{3}$ on the sintering and dielectric characteristics of ($Pb_{x}Ca_{1-x}$)$ZrO_{3}$ (Pb($Fe_{2/3}W_{1/3}$)$O_{3}$가 ($Pb_{x}Ca_{1-x}$)$ZrO_{3}$의 소결과 마이크로파 유전 특성에 미치는 영향)

  • Lim, Sang-Kyu;Kim, Duck-Whan;An, Chul
    • Proceedings of the IEEK Conference
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    • 1998.06a
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    • pp.379-382
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    • 1998
  • In this paper, the microwave dielectric properties of the yPb($Fe_{2/3}W_{1/3}$)$O_{3}$ - (1-y)($Pb_{x}Ca_{1-x}$)$ZrO_{3}$ system were investigated. It was found that an addition of Pb($Fe_{2/3}W_{1/3}$)$O_{3}$ promotes the grain growth, the solid solution between the Pb-based perovskite and the Ca-based perovskite and the decreasing of the sintering temperature. Especially, we found that 0.05Pb($Fe_{2/3}W_{1/3}$)$O_{3}$-0.95($Pb_{x}Ca_{1-x}$)$ZrO_{3}$ ceramic has not only lower sintering temperature but also better dielectric properties than those of the (Pb, Ca)$ZrO_{3}$ systems.

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The Effects of CdO Addition on the Orientation Process of Bi-Sr-Ca-Cu-O Supercoducting Thick Film (Bi계 초전도 후막의 배향과정에 CdO 첨가의 영향)

  • 한영희;성태현;한상철;이준성;정상진
    • Proceedings of the Korea Institute of Applied Superconductivity and Cryogenics Conference
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    • 1999.02a
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    • pp.47-50
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    • 1999
  • The orientation mechanism of an amorphous $Bi_{2}$$Sr_{2}$$Ca_{2 x}$$Cd_{x}$$Cu_{3}$$O_{y}$ phase were studied by using the dilatometry. The amorphous $Bi_{2}$$Sr_{2}$$Ca_{2 x}$$Cd_{x}$$Cu_{3}$$O_{y}$ samples brought about a volume shrinkage at the onset of the crystallization of a $Bi_{2}$$Sr_{2}$$CaCu_{2}$$O_{6}$phase around $400^{\circ}C$. The random crystal growth of $Bi_{2}$$Sr_{2}$$CaCu_{2}$$O_{8}$ phase around $800^{\circ}C$. yielded a rapid volume expansion and after then samples shrinmed, accompanied with the crystal orientation. The$Bi_{2}$$Sr_{2}$$Ca_{2 x}$$Cd_{x}$$Cu_{3}$$O_{y}$ (x=0.4) sample exhibited the best-oriented structure because the liquid phase formed seemed to have the lowest viscosity which would contributed to the easy collapse of the card-house structure.

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Properties of Hydration and Strength of Sol-gol Derived Fine Particle in the System $CaO-P_2O_5-SiO_2$ (졸겔법에 의한 $CaO-P_2O_5-SiO_2$계 미세분말의 수화 및 강도특성)

  • 이형우;김정환
    • Journal of the Korean Ceramic Society
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    • v.31 no.10
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    • pp.1231-1239
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    • 1994
  • In this study, gel powder which had relatively high hydration reactivity in CaO and P2O5 rich composition of CaO-P2O5-SiO2-H2O system was prepared by sol-gel process and its hydrated specimen was manufactured. The it was investigated to appropriate calcination temperature in sol-gel process which hydrated specimen of gel powder have proven to strength and the effect of factors influenced strength in hydration process. The major product of before and after hydration reaction was hydroxyapatite, and crystalline phase of C-S-H was already formed during gelation process. After hydration reaction of pressed specimen, crystalline phase of C-S-P-H was formed. It was hydrated product of silicocarnotite (5CaO.P2O5.SiO2). Gel phases of C-S-H and C-S-P-H occured as a result of partial substitution of amorphous silica by P2O5 was formed. The strength of hydrated hardened body is developed by strong bonding and bridging between the gel phases of C-S-H or C-S-P-H and the crystalline products such as hydroxyapatite, Ca(OH)2 C-S-H and C-S-P-H. In addition, the ultrafine gel powder have an great effect on increase of hydration reaction.

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Carbonation of Circulating Fluidized Bed Combustion Fly Ash with Hybrid Reaction

  • Lee, Ki Gang;Bae, Soon Jong
    • Journal of the Korean Ceramic Society
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    • v.55 no.2
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    • pp.160-165
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    • 2018
  • This paper investigates the reaction rate of $CO_2$ storing carbonation hybrid reaction by comparing the behavior of carbonation between $Ca(OH)_2$ and fly ash with that of CFBC (Circulating Fluidized Bed Combustion) containing plenty of Free-CaO. Because fly ash with CFBC contains a lot of unreacted CaO, it cannot be used as a raw material for concrete admixtures and its usages are limited. To reuse such material, we stabilized unreacted CaO by carbonation and investigated the carbonation rate. We used a pH meter and a thermometer to check the rate of the carbonization. Also, we set the contents of fly ash with CFBC, $Ca(OH)_2$, flow and fluid of $CO_2$, respectively, to 100 g, 50 g, 100 ~ 1000 cc/min and 400 g based on the content of Free-CaO. We used carbonated water instead of water, and added an alkaline activator to promote the carbonation rate. As a result, the addition of the alkaline activator and carbonated water promoted the rate of carbonation via a hybrid reaction.

Effects of Fluoride Additions on Sintering and Microwave Dielectric Properties of CaWO$_4$ (Fluoride 첨가에 따른 CaWO$_4$의 소결 및 고주파 유전특성)

  • 이경호;김용철;방재철
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.127-130
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    • 2002
  • In this study, development of a new LTCC material using a non-glassy system was attempted with respect to reducing the fabrication process steps and cost down. Lowering the sintering temperature can be achieved by liquid phase sintering. For LTCC application, the starting material must have quality factor as high as possible in microwave frequency range. And also, the material should have a low dielectric constant for enhancing the signal propagation speed. Regarding these factors, dielectric constants of various materials were estimated by the Clausius-Mosotti equation. Among them, CaWO$_4$ was tamed out the suitable LTCC material. CaWO$_4$ can be sintered up to 98% of full density at 1200$^{\circ}C$ for 3 hours. It's measured dielectric constant, quality factor, and temperature coefficient of resonant frequency were 10.15, 62880GHz, and -27.8ppm/$^{\circ}C$, respectively. In order to modify the dielectric properties and densification temperature, 0.5∼1.5 wt% LiF were added to CaWO$_4$. LiF addition reduced the sintering temperature/time down to 800$^{\circ}C$/10∼30min due to the reactive liquid phase sintering. Dielectric constant lowered from 10.15 to 9.38 and Q x fo increased up to 92000GHz with increasing LiF content.

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Multiple Candidate Matching Pursuit (다중 후보 매칭 퍼슛)

  • Kwon, Seokbeop;Shim, Byonghyo
    • Journal of Broadcast Engineering
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    • v.17 no.6
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    • pp.954-963
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    • 2012
  • As a greedy algorithm reconstructing the sparse signal from underdetermined system, orthogonal matching pursuit (OMP) algorithm has received much attention. In this paper, we multiple candidate matching pursuit (MuCaMP), which builds up candidate support set in every iteration and uses the minimum residual at last iteration. Using the restricted isometry property (RIP), we derive the sufficient condition for MuCaMP to recover the sparse signal exactly. The MuCaMP guarantees to reconstruct the K-sparse signal when the sensing matrix satisfies the RIP constant ${\delta}_{N+K}<\frac{\sqrt{N}}{\sqrt{K}+3\sqrt{N}}$. In addition, we show a recovery performance both noiseless and noisy measurements.

The Effects of Wood Rotting Fungi and Laccase on Destaining of Dyes and KP Bleaching Effluen

  • Cho, Nam-Seok;Park, J.M.;Choi, T.H.;Matuszewska, A.;Jaszek, M.;Grzywnowicz, K.;Malarczyk, E.;Trojanowski, K.;Leonowicz, A.
    • Journal of the Korean Wood Science and Technology
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    • v.27 no.4
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    • pp.72-79
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    • 1999
  • The ability of several wood rotting fungi for decolorization of two anthracene derivatives, Carminic acid (CA) and Remazol brilliant blue R (RBBR), and hardwood KP bleaching liquor (BL) as well as laccase activities in these fungi were studied. The enzyme activity appeared exclusively in fungi destaining RBBR and CA, but in the case of BL, such relationship was not observed. The laccase enzyme was released into the decolorization media and its inducible (but not constitutive) forms shown destaining activity. The purified inducible forms of Kuehneromyces mutabilis and Pleurotus ostreatus laccase destained CA. Thus the possible differentiation between specificity of particular LAC forms was confirmed. In addition the nitrogen starvation induced both laccase and CA destaining activities, but the increase was higher for decolorization of CA than LAC activity. Probably LAC would be only partly responsible for decolorization of this dye. This results suggested that purified LACs decolorize CA, however its destaining activities were considerably lower than the activities on syringaldazine.

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