• Title/Summary/Keyword: CVS

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Genotypic Variations among Human Caliciviruses in Korea: 1987-1994 (한국에 산재하는 사람 Caliciviruses의 다양한 유전자군: 1987-1994년)

  • Nam, Ki-Bum;Kim, Ji-Aee;Yang, Jai-Myung;Kim, Kyung-Hee
    • The Journal of Korean Society of Virology
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    • v.27 no.2
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    • pp.185-195
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    • 1997
  • Sequence comparison of the RNA-dependent RNA polymerase of human caliciviruses (HuCVs) from Korean children with gastroenteritis revealed significant genetic variation among them. cDNA clones were produced from the HuCVs collected from pediatric population during a period of 1987-1994. The application of reverse transcription-polymerase chain reaction (RT-PCR) using primers directed to the RNA-dependent RNA polymerase region within ORF1 of Norwalk virus (NV) showed that 13.7% of HuCVs yielded PCR products of similar size to the NV prototype, NV8FIIa/68/US, with exceptions of HuCV 185/87/Korea and HuCV 1115/90/Korea. Computer analyses showed that the PCR products had a continuous protein encoding frame on the positive strand, and contained GLPSG and YGDD amino acid motifs at the predicted distance from primers. Alignment of the amino acid sequences of HuCVs with previously published sequences for Snow Mountain agent (SMA), NV, and Sapporo/82/Japan indicated that these strains can be divided into four major genogroups. There were 10 (45%) SMA-like CVs, one (4.5%) NV-like HuCVs, two (9%) Sapporo-like HuCVs, and nine (41%) unidentified HuCVs. This fourth genogroup should be investigated further. HuCV 185/87/Korea and HuCV 1115/90/Korea, Sapporo-like CVs, were genetically distinct from previously characterized HuCVs and more closely related to known animal CVs. One of the animal CV-like strain, HuCV 185/87/Korea, showed nucleotide and amino acid homology of only 67% and 73% with the prototype Sapporo/82/Japan. Further characterization of animal and human CV genomes and studies of possible cross-transmission of CVs from animals to humans are likely to be beneficial in understanding the epidemiology of HuCVs.

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Clinical Outcome of Nonfistulous Cerebral Varices: the Analysis of 39 Lesions

  • Kim, Hye Seon;Park, Seong-Cheol;Ha, Eun Jin;Cho, Wong-Sang;Kim, Seung-Ki;Kim, Jeong Eun
    • Journal of Korean Neurosurgical Society
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    • v.61 no.4
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    • pp.485-493
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    • 2018
  • Objective : Cerebral varices (CVs) without an arteriovenous shunt, so called nonfistulous CVs, are very rare, and their etiology and natural course are not well understood. The aim of this study is to evaluate the clinical outcomes of nonfistulous CVs by the analysis of 39 cases. Methods : From 2000 to 2015, 22 patients with 39 nonfistulous CVs (${\geq}5mm$) were found by searching the medical and radiologic records of our institute. Clinical data and radiological data including numbers, sizes and locations of CVs and associated anomalies were retrospectively collected and analyzed. Previously reported cases in literature were reviewed as well. Results : The mean age of the patients was 21 years (range, 0-78 years). On average, $1.8{\pm}1.2CVs$ were found per patient. CVs were categorized as either fusiform or saccular depending on their shapes. Two patients had saccular type CVs, seventeen patients had fusiform types, and three patients had both fusiform and saccular CVs. Eight patients had associated compromise of the vein of Galen and the straight sinus. Four of those patients had sinus pericranii, as well. Five patients had CVs that were distal draining veins of large developmental venous anomalies. One patient had associated migration anomaly, and two patients had Sturge-Weber syndrome. Six patients with an isolated cerebral varix were observed. Of the 39 CVs in 22 patients, 20 lesions in 14 patients were followed up in outpatient clinics with imaging studies. The average follow-up duration was 6.6 years. During this period, no neurological events occurred, and all the lesions were managed conservatively. Conclusion : Nonfistulous CVs seemed to be asymptomatic in most cases and remained clinically silent. Hence, we suggest conservative management.

An Experimental Study on Exhaust Gas Reduction of Diesel Oxidation Catalyst by CVS-75 Mode in Light Duty Diesel Engine (小型디젤機關에서 CVS-75 모드에 따른 디젤 酸化觸媒裝置의 排出가스 低減에 關한 實驗的 硏究)

  • 한영출;김종춘;오용석
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.4
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    • pp.457-461
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    • 1999
  • Recently, increasing usage of diesel vehicle, many countries try to reduce the pollutant materials by emission regulation standard. Particularly, in our country, the supplement ratio of diesel vehicle is high, and air pollution by particulate matter(PM) is very serious. So, in theoretical study wer analyzed the formation principle of gaseous emission and PM, the characteristics of CVS-75 mode. In experimental study, we tested exhaust gas reduction of emission and PM, the characteristics of CVS-75 mode. In experimental study, we tested exhaust gas reduction of disel oxidation catalyst(DOC) by CVS-75 mode in light duty diesel vehicle. In case of an automobiletest with the 2,956cc diesel engine which DOC was equipped, CVS-75 mode which is similar to driving conditions on the road was chosen as the restrictive mode of light duty diesel automobile in our country. According to the Pt, the reduction rate of exhaust emission was estimated with using 0.1% high sulfur fuel and 0.05% low sulfur fuel.

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CATACLYSMIC VARIABLES : SOURCES OF STOCHASTIC GRAVITATIONAL WAVE BACKGROUND (격변 변광성 : 확률적 중력파동배경의 샘)

  • Song, Doo-Jong
    • Publications of The Korean Astronomical Society
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    • v.22 no.4
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    • pp.113-132
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    • 2007
  • On the framework of stochastic gravitational wave background(SGWB) by compact binary systems, we studied the strain spectra of SGWB produced by cosmological cataclysmic variables(CV). For this we reviewed the empirical properties of CVs by using newly published CV catalogue and calculated the cosmological densities of CVs considering the galaxy luminosity function and cosmic stellar birth rate function. Assuming the secular evolution of CVs, we calculated the time scale of CV gravitational wave(GW) radiation and derived formulae for the strain spectra of SGWB by cosmological CVs.

Long Term Follow-Up of Cyclic Vomiting Syndrome (주기성 구토증(cyclic vomiting syndrome)의 장기 추적 관찰 -이형 편두통(migraine variant)으로의 이행 과정인가?-)

  • Hwang, Jin-Bok;Oh, Hee-Jong;Choi, Kwang-Hae
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.75-83
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    • 2000
  • Cyclic vomiting syndrome(CVS) is a disorder of unknown etiology that is characterized by its clinical pattern of intermittent episodes of severe vomiting, similar in time of onset and duration, with no symptoms during the intervening period. By definition, CVS is an idiopathic disorder that requires exclusionary laboratory testing. Not only can it be mimicked by many specific disorders, eg, surgical, neurologic, endocrine, metabolic, renal, but within idiopathic CVS there may be specific subgroups that have different mechanisms. It has been reported that CVS usually begins in toddlers and resolves during adolescence. Migraine is also self-limiting episodic condition of children and the clinical features of migraine and CVS show considerable similarity. It is proposed that CVS is a condition related to migraine. This paper reports clinical courses of long term follow-up and reversible EEG changes in three patients whose history included CVS. Clinical situations of attack interval, duration and associated symptoms had changed variablely in each patients through long term follow-up period. Cyclic vomiting subsided in two cases. Abnormal delta activity was seen during episodes and resolved at follow-up, when the patient asymptomatic. The brain wave changes support the interpretation of CVS as a migraine variant.

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A Study on Relative Importance of Service Convenience in the Convenience Store Using AHP : Gap Analysis between Consumers and Store Owners (AHP를 활용한 편의점 서비스 편의성의 상대적 중요도 연구 : 경영자와 소비자 간의 Gap Analysis)

  • Kim, Kihyung;Han, SangLin;Kim, Juyeon
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.42 no.3
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    • pp.142-156
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    • 2019
  • [Purpose] It aims to suggest the differential factors to enhance the customer satisfaction and to activate the shopping in the convenience store (CVS). [Methodology] Convenience store service convenience (CVS SERVCON) was developed at the first time and the gap of relative importance level between the owners and the consumers was assessed by AHP analysis method..[Findings] First, the importance of access convenience was assessed as the first priority in both CVS owners' group and the consumers' group, while the detailed elements showed the differences which required the improvements. Based on the consumers' assessment, the importance of location was relatively low. They assessed relatively high on 24 hours operation of CVS and personal services. Second with respect to the transaction convenience, CVS owners' group rated it as the fourth priority while the consumers' group rated as the second, which requires the improvement. Third in terms of benefit utility and value-added service of post-benefit convenience which are the sub-factors of benefit convenience, the rate on the importance from the consumers showed higher than that from the owners, which requires the improvement. [Implications] Based on this study results, CVS operating companies are anticipated to be able to satisfy the customers, moreover, to secure the loyal customers if they concentrate the resources to develop the differentiation strategy on the areas where the consumers' demands are high while performs the maintenance strategy on the areas where their demands are low. In addition, this study contributed the theoretical expansion of SERVCON upon development of CVS SERVCON to comply with its definition.

TCA: A Trusted Collaborative Anonymity Construction Scheme for Location Privacy Protection in VANETs

  • Zhang, Wenbo;Chen, Lin;Su, Hengtao;Wang, Yin;Feng, Jingyu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.10
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    • pp.3438-3457
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    • 2022
  • As location-based services (LBS) are widely used in vehicular ad-hoc networks (VANETs), location privacy has become an utmost concern. Spatial cloaking is a popular location privacy protection approach, which uses a cloaking area containing k-1 collaborative vehicles (CVs) to replace the real location of the requested vehicle (RV). However, all CVs are assumed as honest in k-anonymity, and thus giving opportunities for dishonest CVs to submit false location information during the cloaking area construction. Attackers could exploit dishonest CVs' false location information to speculate the real location of RV. To suppress this threat, an edge-assisted Trusted Collaborative Anonymity construction scheme called TCA is proposed with trust mechanism. From the design idea of trusted observations within variable radius r, the trust value is not only utilized to select honest CVs to construct a cloaking area by restricting r's search range but also used to verify false location information from dishonest CVs. In order to obtain the variable radius r of searching CVs, a multiple linear regression model is established based on the privacy level and service quality of RV. By using the above approaches, the trust relationship among vehicles can be predicted, and the most suitable CVs can be selected according to RV's preference, so as to construct the trusted cloaking area. Moreover, to deal with the massive trust value calculation brought by large quantities of LBS requests, edge computing is employed during the trust evaluation. The performance analysis indicates that the malicious response of TCA is only 22% of the collaborative anonymity construction scheme without trust mechanism, and the location privacy leakage is about 32% of the traditional Enhanced Location Privacy Preserving (ELPP) scheme.

Analysis of the Driving Patterns Concerned with Fuel Economy in Seoul Metropolitan Area (서울특별시의 주행특성 분석에 관한 연구)

  • Lee, Y.J.;Kwon, O.S.;Koh, C.J.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.3 no.2
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    • pp.1-15
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    • 1995
  • The driving patterns in Seoul metropolitan area were surveyed in an experiment involving 1,212km of driving along seventeen representative routes. The speed and fuel consumption data were recorded and the influence of driving patterns on vehicle fuel economy was analyzed by statistical techniques. The results showed that characteristics of driving in Seoul metropolitan area are far different from that of CVS-75 mode and then on-road fuel economy in Seoul may be small as compared with that of CVS-75 mode. Finally, it was proposed that CVS-75 mode fuel economy should be modified by applying adjustment factor to represent actual on-road fuel economy.

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A Semi-empirical Mass-loss Rate in Short-period CVs

  • Kim, Woong-Tae;Sirotkin, Fedir V.
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.76.2-76.2
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    • 2010
  • We present the final results of our study on the mass-loss rate of donor stars in cataclysmic variables (CVs). Observed donors are oversized in comparison with those of isolated single stars of the same mass, which is thought to be a consequence of the mass loss. Using the empirical mass-radius relation of CVs and the homologous approximation for changes in effective temperature T2, orbital period P, and luminosity of the donor with the stellar radius, we find the semi-empirical mass-loss rate M2dot of CVs as a function of P. The derived M2dot is at ~10-9.5-10-10 $M\odot$/yr and depends weakly on P when P > 90 min, while it declines very rapidly towards the minimum period when P < 90 min. The semi-empirical M2dot is significantly different from, and has a less-pronounced turnaround behavior with P than suggested by previous numerical models. The semi-empirical P-M2dot relation is consistent with the angular momentum loss due to gravitational wave emission, and strongly suggests that CV secondaries with 0.075 $M\odot$ < M2 < 0.2 $M\odot$ are less than 2 Gyrs old. When applied to selected eclipsing CVs, our semi-empirical mass-loss rates are in good agreement with the accretion rates derived from the effective temperatures T1 of white dwarfs. Based on the semi-empirical M2dot, SDSS 1501 and 1433 systems that were previously identified as post-bounce CVs have yet to reach the minimal period.

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Chronic Administration of Monosodium Glutamate under Chronic Variable Stress Impaired Hypothalamic-Pituitary-Adrenal Axis Function in Rats

  • Seo, Hee-Jeong;Ham, Hyang-Do;Jin, Hyung-Yong;Lee, Woo-Hyung;Hwang, Hyun-Sub;Park, Soon-Ah;Kim, Yong-Sung;Choi, Suck-Chei;Lee, Seoul;Oh, Kyung-Jae;Kim, Byung-Sook;Park, Byung-Rim;Lee, Moon-Young
    • The Korean Journal of Physiology and Pharmacology
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    • v.14 no.4
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    • pp.213-221
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    • 2010
  • The hypothalamic-pituitary-adrenal (HPA) axis is the primary endocrine system to respond to stress. The HPA axis may be affected by increased level of corticotrophin-releasing factors under chronic stress and by chronic administration of monosodium glutamate (MSG). The purpose of this study was to investigate whether chronic MSG administration aggravates chronic variable stress (CVS)-induced behavioral and hormonal changes. Twenty-four adult male Sprague-Dawley rats, weighing 200~220 g, were divided into 4 groups as follows: water administration (CON), MSG (3 g/kg) administration (MSG), CVS, and CVS with MSG (3 g/kg) administration (CVS+MSG). In addition, for the purpose of comparing the effect on plasma corticosterone levels between chronic stress and daily care or acute stress, 2 groups were added at the end of the experiment; the 2 new groups were as follows: naive mice (n=7) and mice exposed to restraint stress for 2 h just before decapitation (A-Str, n=7). In an open field test performed after the experiment, the CVS+MSG group significant decrease in activity. The increase in relative adrenal weights in the CVS and CVS+MSG group was significantly greater than those in the CON and/or MSG groups. In spite of the increase in the relative adrenal weight, there was a significant decrease in the plasma corticosterone levels in the CVS+MSG group as compared to all other groups, except the naive group. These results suggest that impaired HPA axis function as well as the decrease in the behavioral activity in adult rats can be induced by chronic MSG administration under CVS rather than CVS alone.