• Journal of the Korean Society of Radiology
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• v.83 no.1
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• pp.3-27
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• 2022

Cardiac CT has been proven to provide diagnostic and prognostic evaluation of coronary artery disease for cardiovascular risk stratification and treatment decision-making based on rapid technological development and various research evidence. Coronary CT angiography has emerged as a gateway test for coronary artery disease that can reduce invasive angiography due to its high negative predictive value, but the diagnostic specificity is relatively low. However, coronary CT angiography is likely to overcome its limitations through functional evaluation to identify the hemodynamic significance of coronary artery disease by analyzing myocardial perfusion and fractional flow reserve through cardiac CT. Recently, studies have been actively conducted to incorporate artificial intelligence to make this more objective and reproducible. In this review, functional imaging techniques of cardiac computerized tomography are explored.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.32-34
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• 2002

Over the past two decades there has been a tremendous growth in the number of synchrotron radiation facilities in the world and also in Japan. The high flux and brightness radiation which derive from the third generation low emittance rings provide an ideal source for many applications in the medical sciences. The application of synchrotron radiation to medical imaging started in the early 80's in U.S.A, followed by European countries such as Germany and Russia. In Japan, researchs on intravenous coronary angiography started in 1884 at the Institute for High Energy Phisics(KEK) in Tsukuba. At present, it is the only application of syncrotron radiation which is at the stage of human study. In '90s, newer techniques such as phase and refraction contrast imaging appeared which are at the in vitro or animal study stage. Various types of x-ray CT have also been developed for three-dimensional imaging of the subjects. The present status of medical applications of synchrotron radiation in Japan is reviewed.

• 제어로봇시스템학회:학술대회논문집
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• 1995.10a
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• pp.248-251
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• 1995

Nowadays, the internal images of a human body can be easily provided by the ultrasound imaging, the X-ray CT, or the MRI device, among which the ultrasound imaging device has good resolution for soft tissues of a human body compared with the other devices. Furthermore, the use of ultrasound imaging devices will increase in future especially in the obstetrics, territory, since it does not give harm to the human body. Although several techniques have been investigated until now in order to extract organs from ultrasound images, very few of them have achieved satisfactory results because of low contrast and high noise nature of images. This paper proposes a technique for automatic extraction of the gall bladder area from ultrasound images. The proposed technique first extracts a small reliable area of a gall bladder from an ultrasound image employing smoothing, binarization, expanding and shrinking, and labeling, and then expands the area referring to the binarized version of the original image. The technique is examined its performance by real ultrasound images of a gall bladder and satisfactory results are obtained. Some problems to be solved are discussed finally.

• Journal of Information Processing Systems
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• v.15 no.2
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• pp.288-304
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• 2019

The growth of telemedicine-based wireless communication for images-magnetic resonance imaging (MRI) and computed tomography (CT)-leads to the necessity of learning the concept of image compression. Over the years, the transform based and spatial based compression techniques have attracted many types of researches and achieve better results at the cost of high computational complexity. In order to overcome this, the optimization techniques are considered with the existing image compression techniques. However, it fails to preserve the original content of the diagnostic information and cause artifacts at high compression ratio. In this paper, the concept of histogram based multilevel thresholding (HMT) using entropy is appended with the optimization algorithm to compress the medical images effectively. However, the method becomes time consuming during the measurement of the randomness from the image pixel group and not suitable for medical applications. Hence, an attempt has been made in this paper to develop an HMT based image compression by utilizing the opposition based improved harmony search algorithm (OIHSA) as an optimization technique along with the entropy. Further, the enhancement of the significant information present in the medical images are improved by the proper selection of entropy and the number of thresholds chosen to reconstruct the compressed image.

• Journal of Periodontal and Implant Science
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• v.48 no.4
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• pp.202-212
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• 2018

Purpose: Bone-to-implant contact (BIC) is difficult to measure on micro-computed tomography (CT) because of artifacts that hinder accurate differentiation of the bone and implant. This study presents an advanced algorithm for measuring BIC in micro-CT acquisitions using a spiral scanning technique, with improved differentiation of bone and implant materials. Methods: Five sandblasted, large-grit, acid-etched implants were used. Three implants were subjected to surface analysis, and 2 were inserted into a New Zealand white rabbit, with each tibia receiving 1 implant. The rabbit was sacrificed after 28 days. The en bloc specimens were subjected to spiral (SkyScan 1275, Bruker) and round (SkyScan 1172, SkyScan 1275) micro-CT scanning to evaluate differences in the images resulting from the different scanning techniques. The partial volume effect (PVE) was optimized as much as possible. BIC was measured with both round and spiral scanning on the SkyScan 1275, and the results were compared. Results: Compared with the round micro-CT scanning, the spiral scanning showed much clearer images. In addition, the PVE was optimized, which allowed accurate BIC measurements to be made. Round scanning on the SkyScan 1275 resulted in higher BIC measurements than spiral scanning on the same machine; however, the higher measurements on round scanning were confirmed to be false, and were found to be the result of artifacts in the void, rather than bone. Conclusions: The results of this study indicate that spiral scanning can reduce metal artifacts, thereby allowing clear differentiation of bone and implant. Moreover, the PVE, which is a factor that inevitably hinders accurate BIC measurements, was optimized through an advanced algorithm.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.11
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• pp.1664-1671
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• 2004

It is necessary to have a model that describes the feature of the knee Joint with a sufficient accuracy. Koreans, however, do not have their own knee joint model to be used in the total knee replacement arthroplasty. They have to use European or American models which do not match Koreans. Three-dimensional visualization techniques are found to be useful in a wide range of medical applications. Three-dimensional imaging studies such as CT(computed tomography) and MRI(magnetic resonance image) provide the primary source of patient-specific data. Three-dimensional knee joint models were constructed by image processing of the CT data of 10 subjects. Using the constructed model, the dimensions of Korean knee joint were measured. And this study proposed a three-dimensional model and data, which can be helpful to develop Korean knee implants and to analyze knee joint movements.

• Nuclear Engineering and Technology
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• v.38 no.3
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• pp.239-250
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• 2006

Computational anthropomorphic phantoms are computer models of human anatomy used in the calculation of radiation dose distribution in the human body upon exposure to a radiation source. Depending on the manner to represent human anatomy, they are categorized into two classes: stylized and tomographic phantoms. Stylized phantoms, which have mainly been developed at the Oak Ridge National Laboratory (ORNL), describe human anatomy by using simple mathematical equations of analytical geometry. Several improved stylized phantoms such as male and female adults, pediatric series, and enhanced organ models have been developed following the first hermaphrodite adult stylized phantom, Medical Internal Radiation Dose (MIRD)-5 phantom. Although stylized phantoms have significantly contributed to dosimetry calculation, they provide only approximations of the true anatomical features of the human body and the resulting organ dose distribution. An alternative class of computational phantom, the tomographic phantom, is based upon three-dimensional imaging techniques such as magnetic resonance (MR) imaging and computed tomography (CT). The tomographic phantoms represent the human anatomy with a large number of voxels that are assigned tissue type and organ identity. To date, a total of around 30 tomographic phantoms including male and female adults, pediatric phantoms, and even a pregnant female, have been developed and utilized for realistic radiation dosimetry calculation. They are based on MRI/CT images or sectional color photos from patients, volunteers or cadavers. Several investigators have compared tomographic phantoms with stylized phantoms, and demonstrated the superiority of tomographic phantoms in terms of realistic anatomy and dosimetry calculation. This paper summarizes the history and current status of both stylized and tomographic phantoms, including Korean computational phantoms. Advantages, limitations, and future prospects are also discussed.

• The Journal of Korean Medicine
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• v.35 no.3
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• pp.70-92
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• 2014

Objectives: Due to advance of science and IT technology, high tech imaging equipment like ultrasonography, CT, MRI and PET scan is constantly being developed and progressed; use of these techniques is needed for Korean medicine. Methods: Historical study was undertaken on the evidence of using ultrasonography. Normal organs and various sorts of diseases were also observed by ultrasonography. Results: Korean medicine judges disease of internal organs and condition of health by symptoms of functional disease and organic disease based on anatomical theory. Ultrasonography based on anatomical theory is non-invasive and free from radiation exposure and can be performed directly from clinical practice in real-time. Ultrasonography can be a big help for securing the stability of the internal organs in inserting needles in the thorax and abdomen as well as diagnosing functional and organic diseases based on anatomical theory. Conclusion: We look forward to a great development of scientification and objectification of Korean medicine by using and researching imaging equipment based on anatomical theory as well as ultrasonography.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.1
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• pp.1-8
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• 2022

Erythrocyte sedimentation rate (ESR) evaluation is a useful tool for monitoring disease activity in various inflammatory and non-inflammatory conditions. ESR is known to be influenced by a multitude of confounding factors. The present study aimed to assess the possible determinants of the ESR and its relationship with various risk factors involved in ischemic stroke. ESR and other hematological and biochemical parameters were investigated in 163 ischemic stroke patients (107 males and 56 females) selected based on imaging techniques including magnetic resonance imaging (MRI) or computed tomography (CT) scans. Statistical analysis was performed using the SPSS 16.0 software. Linear regression analysis showed a significant inverse relationship of hemoglobin (Hb) and hematocrit or packed cell volume (PCV) (P<0.001 for females; P<0.01 for males) with the ESR. It was observed that the red blood cell (RBC) count was not strongly correlated with the ESR (P<0.05 for both males and females). It was also observed that sex significantly affected the variables determining the ESR levels, whereas age had no effect. Gender differences were also observed with respect to Hb, RBC, PCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ESR. The possible determinants of higher ESR levels in ischemic stroke may be sex, Hb, hematocrit, and RBC count, but the role of other clinical and laboratory parameters cannot be underestimated.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.1 s.173
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• pp.196-205
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• 2000

Computed Tomography (CT), Nuclear Magnetic Resonance Imaging (MR1) and some ultrasound techniques make it possible to obtain cross sections of human body or mechanical parts. In CAD system, a series of sectional surfaces can also be obtained from solid models of 3D objects. In this paper we introduce a tetrahedral meshing algorithm from these series of general sections using basic operators. In this scheme. general sections of three-dimensional object are triangulated first and side surfaces between two sections are triangulated by the use of tiling process. Finally tetrahedral meshing process is performed on each layer of 3D objects, which is composed of two general sections and one side surface.