• Title/Summary/Keyword: CT R&D

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3D Medical Image Data Augmentation for CT Image Segmentation (CT 이미지 세그멘테이션을 위한 3D 의료 영상 데이터 증강 기법)

  • Seonghyeon Ko;Huigyu Yang;Moonseong Kim;Hyunseung Choo
    • Journal of Internet Computing and Services
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    • v.24 no.4
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    • pp.85-92
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    • 2023
  • Deep learning applications are increasingly being leveraged for disease detection tasks in medical imaging modalities such as X-ray, Computed Tomography (CT), and Magnetic Resonance Imaging (MRI). Most data-centric deep learning challenges necessitate the use of supervised learning methodologies to attain high accuracy and to facilitate performance evaluation through comparison with the ground truth. Supervised learning mandates a substantial amount of image and label sets, however, procuring an adequate volume of medical imaging data for training is a formidable task. Various data augmentation strategies can mitigate the underfitting issue inherent in supervised learning-based models that are trained on limited medical image and label sets. This research investigates the enhancement of a deep learning-based rib fracture segmentation model and the efficacy of data augmentation techniques such as left-right flipping, rotation, and scaling. Augmented dataset with L/R flipping and rotations(30°, 60°) increased model performance, however, dataset with rotation(90°) and ⨯0.5 rescaling decreased model performance. This indicates the usage of appropriate data augmentation methods depending on datasets and tasks.

An Experimental Comparative Study of Radiography, Ultrasonography and CT Imaging in the IV Catheter Fragment (정맥내 카테터 조각의 엑스선, 초음파 및 CT 영상의 실험적 비교 연구)

  • Kweon, Dae Cheol
    • Journal of radiological science and technology
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    • v.39 no.2
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    • pp.185-191
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    • 2016
  • The objective of this study was to detect the fragments generated during IV (intravenous) catheter injection of contrast medium and drug administration in a clinical setting and removal was performed by experimentally producing a phantom, and to compare the radiography, ultrasonography, and multi-detector computed tomography (MDCT) imaging and radiation dose. A 1 cm fragment of an 18 gage Teflon$^{(R)}$ IV catheter with saline was inserted into the IV control line. Radiography, CT, and ultrasonography were performed and radiography and CT dose were calculated. CT and ultrasonography showed an IV catheter fragment clinically and radiography showed no visible difference in the ability to provide a useful image of an IV catheter fragment modality (p >.05). Radiography of effective dose ($0.2139mSv{\cdot}Gy^{-1}{\cdot}cm^{-2}$) form DAP DAP ($0.93{\mu}Gy{\cdot}m^2 $), and dose length product (DLP) ($201mGy{\cdot}cm$) to effective dose was calculated as 0.483 mSv. IV catheter fragment were detected of radiography, ultrasonography and CT. These results can be obtained by menas of an excellent IV catheter fragment of detection capability CT. However, CT is followed by radiation exposure. IV catheter fragment confirming the position and information recommend an ultrasonography.

Cut-Through versus Cut-Out: No Easy Way to Predict How Single Lag Screw Design Cephalomedullary Nails Used for Intertrochanteric Hip Fractures Will Fail?

  • Garrett W. Esper;Nina D. Fisher;Utkarsh Anil;Abhishek Ganta;Sanjit R. Konda;Kenneth A. Egol
    • Hip & pelvis
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    • v.35 no.3
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    • pp.175-182
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    • 2023
  • Purpose: This study aims to compare patients in whom fixation failure occurred via cut-out (CO) or cut-through (CT) in order to determine patient factors and radiographic parameters that may be predictive of each mechanism. Materials and Methods: This retrospective cohort study includes 18 patients with intertrochanteric (IT) hip fractures (AO/OTA classification 31A1.3) who underwent treatment using a single lag screw design intramedullary nail in whom fixation failure occurred within one year. All patients were reviewed for demographics and radiographic parameters including tip-to-apex distance (TAD), posteromedial calcar continuity, neck-shaft angle, lateral wall thickness, and others. Patients were grouped into cohorts based on the mechanism of failure, either lag screw CO or CT, and a comparison was performed. Results: No differences in demographics, injury details, fracture classifications, or radiographic parameters were observed between CO/CT cohorts. Of note, a similar rate of post-reduction TAD>25 mm (P=0.936) was observed between groups. A higher rate of DEXA (dual energy X-ray absorptiometry) confirmed osteoporosis (25.0% vs. 60.0%) was observed in the CT group, but without significance. Conclusion: The mechanism of CT failure during intramedullary nail fixation of an IT fracture did not show an association with clinical data including patient demographics, reduction accuracy, or radiographic parameters. As reported in previous biomechanical studies, the main predictive factor for patients in whom early failure might occur via the CT effect mechanism may be related to bone quality; however, conduct of larger studies will be required in order to determine whether there is a difference in bone quality.

Reference Implementation of OpenVG for Embedded System (임베디드 시스템용 OpenVG 참조 구현)

  • Lee, Sang-Yun;Lee, Kyung-Hee;Kim, Sung-Hwan;Chung, Ji-Hoon;Choi, Byung-Uk
    • Proceedings of the Korean Information Science Society Conference
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    • 2007.06b
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    • pp.161-166
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    • 2007
  • 본 논문에서는 크로노스 그룹에서 제정한 스케일러블 벡터 그래픽 하드웨어 가속을 위한 표준인 OpenVG를 소프트웨어 렌더링 방식으로 구현한 참조 구현을 제안한다. EGL과 OpenVG 엔진이 다양한 임베디드 환경에 쉽게 이식이 가능하도록 설계한 방식을 제시한다 또한 성능 개선을 위해, 채택한 수학 함수와 알고리즘의 선택 배경을 기술하고 최적의 렌더링 방법을 제안한다. 소프트웨어 렌더링 방법으로 구현한 OpenVG를 통해 벡터 이미지를 화면에 출력하는 모습을 보인다. 또한 호환성 테스트 툴인 CTS의 테스트 결과를 제시하며 기존 참조 구현인 Hybrid 사의 참조 구현과 성능 비교 실험 결과를 보인다.

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Effect of Vigna angularis Ethanol Extract on Papain-induced Arthritis in Mice (팥 에탄올 추출물의 Papain 유도 관절염 마우스에서의 항 골관절염 효과)

  • Jeoung, See Hwa;Kim, Seung Hyung;Kim, Hyun Kyu;Yun, Bo Ra;Lee, Hee Woong;Lim, Ju Hwan;Rho, Mun Chual;Kim, Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.665-671
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    • 2012
  • The purpose of this study is to examine the effect of Vigna angularis ethanol extract (VA-E) on papain induced arthritis in C57BL/10 mice. The C57BL/10 mice were injected with papain and oral administration of Vigna angularis ethanol extract (VA-E) at different doses (100 and 200 mg/kg) once a day for 42 days and compared with untreated mice. Histological examination and the measurement of inflammatory cytokine release were performed. The results showed that comparing with untreated mice, the treatment with Vigna angularis ethanol extract (VA-E) decreased the pathological changes of knee joint tissue. The level of inflammatory cytokine secreted from the tissues, such as IL-$1{\beta}$ (interleukin-$1{\beta}$), IL-6 (interleukin-6), TNF-${\alpha}$ (Tumor Necrosis Factor-${\alpha}$), were decreased. These results were confirmed by the quantification of cartilage volume using micro CT scanning. Consequently, Vigna angularis ethanol extract (VA-E) has a therapeutic potential in inflammatory joint diseases such as osteoarthritis.

Characterization of Phosphatidylinositol Glycan, Class K (PIGK) Gene and Analysis of Association with Quantitative Traits in Pigs (돼지 Phosphatidylinositol Glycan, Class K (PIGK) 유전자의 동정과 양적형질과의 연관성 분석)

  • Lim, H.T.;Kim, J.H.;Choi, B.H.;Lee, S.H.;Park, E.W.;Kim, T.H.;Cho, I.C.;Oh, S.J.;Lee, J.G.;Jeon, J.T.
    • Journal of Animal Science and Technology
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    • v.47 no.2
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    • pp.167-176
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    • 2005
  • PIGK(phosphatidylinositol glycan, class K) is a subunit of GPI transamidase that cleaves the signal peptide in proproteins and replaces it with GPI. In addition, the structure and synthesis of GPI are critically involved in some of the cellular actions of insulin. Therefore, PIGK would be essential for mammalian development and many specific cellular functions as well as for metabolic activity of insulin associated with GPI. Two types of" full-length cDNAs of porcine PIGK were cloned through RT-PCR and RACE experiments. One is thought to be a normal form(consist of 395 amino acids) and the other is considered as an alternative spliced form(consist of 371 amino acids) which contains additional 63 bps in intron 7. Since a stop codon was contained within the insertion, the spliced form has a shorter coding sequence than that of normal form. A missense mutation (T314I) in exon 6 was detected and used for genotyping to estimate association with the growth and fat deposition traits for 545 $F_2$ animals(Korean native boars ${\times}$ Landrace). From the PCR-RFLP analysis using HpyCH4III, CT genotype showed highly significant relationship(P< 0.01) with carcass fat contents.

Measurement of Prostate Phantom Volume Using Three-Dimensional Medical Imaging Modalities (3차원 의료영상진단기기를 이용한 가상 전립선 용적 측정)

  • Seoung, Youl-Hun;Joo, Yong-Hyun;Choe, Bo-Young
    • Journal of Biomedical Engineering Research
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    • v.31 no.4
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    • pp.285-291
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    • 2010
  • Recently, advance on various modalities of diagnosing, prostate volume estimation became possible not only by the existing two-dimension medical images data but also by the three-dimensional medical images data. In this study, magnetic resonance image (MRI), computer tomography (CT) and ultrasound (US) were employed to evaluate prostate phantom volume measurements for estimation, comparison and analysis. For the prostate phantoms aimed at estimating the volume, total of 17 models were developed by using devils-tongue jelly and changing each of the 5ml of capacity from 20ml to 100ml. For the volume estimation through 2D US, the calculation of the diameter with C9-5Mhz transducer was conducted by ellipsoid formula. For the volume estimation through 3D US, the Qlab software (Philips Medical) was used to calculate the volume data estimated by 3D9-3Mhz transducer. Moreover, the images by 16 channels CT and 1.5 Tesla MRI were added by the method of continuous cross-section addition and each of imaginary prostate model's volume was yielded. In the statistical analysis for comparing the availability of volume estimation, the correlation coefficient (r) was more than 0.9 for all indicating that there were highly correlated, and there were not statistically significant difference between each of the correlation coefficient (p=0.001). Therefore, the estimation of prostate phantom volume using three-dimensional modalities of diagnosing was quite closed to the actual estimation.

Synthesis and Thermal Properties of Poly(cyclohexylene dimethylene terephthalate-co-butylene terephthalate

  • Lee, Sang-Won;Wansoo Huh;Hong, Yoo-Seok;Lee, Kyung-Mi
    • Macromolecular Research
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    • v.8 no.6
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    • pp.261-267
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    • 2000
  • It is well known that poly(cyclohexylene dimethylene terephthalate) (PCT) is used as the engineering plastics with high melting temperature and fast crystallization rate compared with poly(butylene terephthalate)(PBT). However, poor thermal stability of PCT has limited its practical application due to the drastic decrease of molecular weight during the processing temperature. In order to improve the thermal stability of PCT homopolymer, the copolymer of PCT and PBT was synthesized and the thermal properties of the copolymer have been studied. P(CT/BT) copolymer was obtained by condensation polymerization of DMT, CHDM, and 1,4-butanediol. The chemical structure and composition of the copolymer was investigated by FTIR and NMR analysis. The thermal behavior of copolymer was studied using DSC and it was found that the crystallization-melting behavior of the copolymer was observed for the whole composition range. TGA analysis exhibited that P(CT/BT) copolymer is more stable at the initial stage of thermal decomposition compared with PCT and PBT homopolymers.

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Measurement of the Mucosal Surface Distance in the Early Gastric Cancer Using CT Gastrography (조기 위암에서 CT Gastrography를 이용한 위점막 표면 거리 측정)

  • Choi, Hyang-Hee;Yu, Wan-Sik;Ryeom, Hun-Kyu;Lee, Jae-Hyuk;Choi, Jae-Jeong;Kim, Hee-Su;Cleary, Kevin;Mun, Seong-Ki;Chung, Ho-Young
    • Journal of Gastric Cancer
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    • v.6 no.3
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    • pp.161-166
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    • 2006
  • Purpose: Recently, the incidence of early gastric cancer (EGC) patients is rapidly increased in Korea. However, they're often not perceptible by surgical palpation or inspection. The aim of this study is 1) to develope a software that can locate the tumor and measure the mucosal distance from an anatomic landmark to the tumor using CT gastrography and 2) to compare the distance measured by the developed software with the distance measured by the pathologic findings. Materials and Methods: Between January 2004 and September 2005, sixty patients (male=45, female=15, mean 57.8 years old) estimated for EGC with preoperative CT scans and undergone gastrectomies in Kyungpook National University Hospital were enrolled in this study. Preoperative CT scans were performed after insufflations of room air via 5 Fr NG tube. The scans included the following parameters: (slice thickness/reconstruction interval: 0.625 mm, kVp: 120, mAs: 200). 3D volume rendering and measurement of the surface distance from the pylorus to the EGC were performed using the developed software. Results: The average difference between the lesion to pylorus distances measured from pathologic specimens and CT gastrography was $5.3{\pm}2.9\;mm(range,\;0{\sim}23\;mm)$. The lesion to pylorus distance measured from CT gastrography was well correlated with that measured from the pathologic specimens (r=0.9843, P<0.001). Conclusion: These results suggest that the surface distance from an anatomic landmark to the EGC can be measured accurately by CT gastrography. This technique could be used for preoperative localization of early gastric carcinomas to determine the optimal extent of surgical resection.

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Detecting and Tracking Changes of Mechanical Characteristics in the Trabecular and Cortical Bone of the Lumbar Vertebrae for an Ovariectomised Rat using In-Vivo Micro-CT and Micro Finite Element Analysis (IN-VIVO MICRO-CT 와 미세 유한요소법를 이용한 쥐의 골다공증 해면골과 피질골의 구조적 특성 추적관찰 및 기계적 특성 분석)

  • Ko C.Y.;Woo D.G.;Kim H.S.;Lee B.L.;Tack G.R.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.892-895
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    • 2005
  • This study investigated changes of mechanical characteristics in the trabecular and cortical bone of the lumbar vertebrae of the ovariectomised(OVX) rat. In previous researches, there were many studies for morphology of osteoporotic bones based on Micro-CT (Micro - Computed Tomography). However, there were few studies for detecting and tracking changes of mechanical characteristics in the trabecular bone and cortical bone of the lumbar vertebrae for the OVX rat. For this study, one female Sprague-Dawley rat was used: an OVX rat. The 4th lumbar of the OVX rat was utilized as a specimen. Detecting and tracking changes of mechanical characteristics could be investigated in the trabecular and cortical bone of the lumbar vertebrae for an OVX rat using In-vivo Micro-CT. An OVX rat was scanned at week 0 (just before surgery), at week 4, and week 8 after surgery. Micro finite element(${\mu}\;FE$) analysis was used to investigate mechanical characteristics in the trabecular and cortical bone of the lumbar vertebrae for an OVX rat.

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