• Title/Summary/Keyword: CS model

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Detection for folding of the thrombin binding aptamer using label-free electrochemical methods

  • Cho, Min-Seon;Kim, Yeon-Wha;Han, Se-Young;Min, Kyung-In;Rahman, Md. Aminur;Shim, Yoon-Bo;Ban, Chang-Ill
    • BMB Reports
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    • v.41 no.2
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    • pp.126-131
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    • 2008
  • The folding of aptamer immobilized on an Au electrode was successfully detected using label-free electrochemical methods. A thrombin binding DNA aptamer was used as a model system in the presence of various monovalent cations. Impedance spectra showed that the extent to which monovalent cations assist in folding of aptamer is ordered as $K^+$ > $NH_4^+$ > $Na^+$ > $Cs^+$. Our XPS analysis also showed that $K^+$ and $NH_4^+$ caused a conformational change of the aptamer in which it forms a stable complex with these monovalent ions. Impedance results for the interaction between aptamer and thrombin indicated that thrombin interacts more with folded aptamer than with unfolded aptamer. The EQCM technique provided a quantitative analysis of these results. In particular, the present impedance results showed that thrombin participates a folding of aptamer to some extent, and XPS analysis confirmed that thrombin stabilizes and induces the folding of aptamer.

Primary Dispersion Patterns and Widths of Elements in Altered Granitic Wallrock around the Gold-bearing Quartz Veins at the Mugeug Mine (무극 함금석영맥광상 화강암질모암에서의 원소들의 분산형태와 분산범위)

  • Hwang, In Ho;Chon, Hyo Taek
    • Economic and Environmental Geology
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    • v.27 no.5
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    • pp.451-458
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    • 1994
  • Geochemical studies on gold-bearing quartz veins and granitic wallrocks from the Mugeug mine were carried out in order to investigate primary dispersion patterns of elements and to quantify primary dispersion widths of elements with distance from the gold-bearing quartz veins. The best fitting model of dispersion pattern in altered wallrock around the gold-bearing quartz veins is an exponential function for Au, As, Sb, $Na_2O$ and Sr, and a quadratic function for CaO, $K_2O$, MnO, Ba, Rb and Cs. The primary dispersion widths are 15~343 cm in the hanging wall, and 33~173 cm in the footwall. The width of primary dispersion in the hanging wall is twice as thick as that in the footwall mainly due to the thermal effect and volatile components. The primary dispersion width is increased as the increase of gold-bearing quartz vein width and contents of As and Sb in gold-bearing quartz veins, but is not related to Au content in gold-bearing quartz veins.

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Molecular Dynamics Simulation Study for Hydroxide Ion in Supercritical Water using SPC/E Water Potential

  • Lee, Song Hi
    • Bulletin of the Korean Chemical Society
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    • v.34 no.10
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    • pp.2925-2930
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    • 2013
  • We present results of molecular dynamics simulations for hydroxide ion in supercritical water of densities 0.22, 0.31, 0.40, 0.48, 0.61, and 0.74 g/cc using the SPC/E water potential with Ewald summation. The limiting molar conductance of $OH^-$ ion at 673 K monotonically increases with decreasing water density. It is also found that the hydration number of water molecules in the first hydration shells around the $OH^-$ ion decreases and the potential energy per hydrated water molecule also decreases in the whole water density region with decreasing water density. Unlike the case in our previous works on LiCl, NaCl, NaBr, and CsBr [Lee at al., Chem. Phys. Lett. 1998, 293, 289-294 and J. Chem. Phys. 2000, 112, 864-869], the number of hydrated water molecules around ions and the potential energy per hydrated water molecule give the same effect to cause a monotonically increasing of the diffusion coefficient with decreasing water density in the whole water density region. The decreasing residence times are consistent with the decreasing potential energy per hydrated water molecule.

A Study on the Determinants of Consumer Trust toward Internet-Only Banks (인터넷전문은행의 신뢰 결정요인 연구)

  • Nam, Sang-Wook
    • Journal of Convergence for Information Technology
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    • v.8 no.2
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    • pp.157-162
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    • 2018
  • The purpose of this study is to evaluate the level of trust by financial consumers and attempt to investigate the determinants that influence consumer trust in internet-only banks. For this aim, I conducted an empirical study and the survey results was used to test a structural equation model that analyzed the financial consumer trust and estimated the level of trust for internet-only banks. As a result of the analysis, the three most effective determinants of trust were security, convenience and benefit. Also, the level of financial consumer trust for the internet-only banks, based on the three factors, was later extended to relationship commitment such as renewal and recommendation intentions. Therefore, Internet-only banks need to focus on promoting their trust more effectively for future sustainable growth.

A Study on the Difference of SME's CSR Effects Using the Multi-Group Analysis (다집단 분석을 통한 중소기업의 CSR 효과 차이 연구)

  • Nam, Sang-Wook;Yang, Jin-Whan
    • Journal of Convergence for Information Technology
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    • v.7 no.6
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    • pp.253-258
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    • 2017
  • The purpose of this study is to measure the difference of corporate social responsibility(hereinafter referred to as "CSR") effects on SME's depending on the level of business risk perception. For this aim, we divided the analysis target SEM's into two groups according to the level of business risk perception and examine whether there is any difference in CSR effects through t-test and the test of the structural model invariance across the groups. As a results, the difference of CSR activities between the two groups occurred in the communication and strategy. In terms of CSR effects, there was a gap in the financial performance.

Factors Contributing to Marital Stability of Disabled Women (여성장애인의 결혼안정성 영향 요인 연구)

  • Yang, Jung-Bin
    • Journal of Convergence for Information Technology
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    • v.10 no.3
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    • pp.208-216
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    • 2020
  • This study investigates major contributing factors that determine the marital stability among the disabled women in South Korea. Data collected from 124 women with disabilities were analyzed for this purpose. Multiple regression analysis was used to explore the determinants of the marital instability among the participants. The multiple regression analysis revealed that age, welfare receipt, health condition, depression, marital intimacy, marital satisfaction, marital conflicts and drinking problems were statistically significant predictors to the extent of marital stability among the disabled women in the total model. Based on the study results, several implications such as development of programs to improve marital stability of women with disabilities were discussed.

A Study on the Factor Affecting the Service Commitment in Customer Satisfaction Education: Focused on Financial Institute Employee (고객만족교육에서 서비스몰입에 영향을 미치는 요인에 관한 연구: 금융기관 종사자를 중심으로)

  • Bae, Injoung;Park, Soeun;Choi, Jeongil
    • Journal of Korean Society for Quality Management
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    • v.44 no.1
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    • pp.121-138
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    • 2016
  • Purpose: Financial institute employees have various education programs for enhancing customer satisfaction. The purpose of this study is to explore critical factors that affect the service commitment in the financial institution and to propose the implication for employee's service involvement. Methods: This study is intended to identify how service quality of education, servicescape, and learning motivation affect the service commitment. The research model proposed in this study is tested via a survey of 322 employees for financial institution employees. Results: This study shows that tangibles, reliability, assurance and ambient condition, physical structure, symbolic artifacts and internal motivation, extrinsic motivation significantly influence education satisfaction. Tangibles, reliability and ambient condition, physical structure, symbolic artifacts and internal motivation significantly influence affective service orientation and that tangibles, reliability, assurance and extrinsic motivation significantly influence altruistic service orientation. It also verifies that education satisfaction affective service orientation, and altruistic service orientation positively affect service commitment. Conclusion: This study suggests critical factors to promote service commitment in the financial institute. It has focused on not only the service quality of education program, but also servicescape and learning motivation as the meaningful factors for increasing the employee's service involvement.

Temperature dependent buckling analysis of graded porous plate reinforced with graphene platelets

  • Wei, Guohui;Tahouneh, Vahid
    • Steel and Composite Structures
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    • v.39 no.3
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    • pp.275-290
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    • 2021
  • The main purpose of this research work is to investigate the critical buckling load of functionally graded (FG) porous plates with graphene platelets (GPLs) reinforcement using generalized differential quadrature (GDQ) method at thermal condition. It is supposed that the GPL nanofillers and the porosity coefficient vary continuously along the plate thickness direction. Generally, the thermal distribution is considered to be nonlinear and the temperature changing continuously through the thickness of the nanocomposite plates according to the power-law distribution. To model closed cell FG porous material reinforced with GPLs, Halpin-Tsai micromechanical modeling in conjunction with Gaussian-Random field scheme are used, through which mechanical properties of the structures can be extracted. Based on the third order shear deformation theory (TSDT) and the Hamilton's principle, the equations of motion are established and solved for various boundary conditions (B.Cs). The fast rate of convergence and accuracy of the method are investigated through the different solved examples and validity of the present study is evaluated by comparing its numerical results with those available in the literature. A special attention is drawn to the role of GPLs weight fraction, GPLs patterns through the thickness, porosity coefficient and distribution of porosity on critical buckling load. Results reveal that the importance of thermal condition on of the critical load of FGP-GPL reinforced nanocomposite plates.

Design of Service Provision Framework using Medical Big Data (의료 빅 데이터를 활용한 서비스 제공 프레임워크 설계)

  • Shin, Bong-Hi;Jeon, Hye-Kyoung
    • Journal of Convergence for Information Technology
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    • v.9 no.2
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    • pp.1-6
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    • 2019
  • In this article, we have presented a framework, designed to create new services for businesses, which use large sets of medical data. It is not a simple data analysis step, but it clarifies the purpose of data utilization, analyses it, extracts value from it, and designs a process from actual business or service to an operation. The designed frame work covers the basic architecture and social system model. It was designed, using basic data, which was focused on large sets of medical data, and to be applied to a social system with reference to the designed framework. We are looking forward to create various medical business alliances and services applying the designed framework to the available sets of basic medical data.

Anthropology of power and passion, active nihilism: theme analysis on Sung, Suk-je's novel

  • Lee, Chan
    • Cross-Cultural Studies
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    • v.28
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    • pp.37-53
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    • 2012
  • This paper examines 'an active nihilism' in Suk-je Sung's novels in detail. The focus of this study is formed from the critical mind in a critical perspective that in Korean novels before and after 2000s, characters who embody 'problematic individuals' of $Luk{\acute{a}}cs$ have disappeared and those close to 'active nihilists' has become the mainstream. The most representative example of this phenomenon is Suk-je Sung's novels. 'Active nihilists' in his novels are described as 'ascetics' who mastered various spheres such as 'billiard', 'baduk gambling', 'alcohol', 'dance', and 'book collecting', and so on. In the sense that they reject the transcendental conditions of the modern world and live in the space and time of play in which they can display their passion and potentiality to the maximum, they beings jumping over the 'reality principle'. Also, what they want to repeat is not the endless exchange of labor and capital according to the capitalist system of exchange but rather the repeated existence of their power and passion. This 'anthropology of power and passion' is 'active nihilism' which could be expressed as the 'subject of creating new value' and 'Dionysian affirmation' by Nietzsche. Suk-je Sung's novels sharply prove the stylistic essence of 'a novel' which has to create its own form every time, constantly renewing the narrative style of the past ideal model. In this respect, they are very problematic and his innovation of a form draws the attention. Further, this will certainly be the important object of research in the diachronic dimension of contemporary Korean novel.