• Journal of computational fluids engineering
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• v.8 no.4
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• pp.26-33
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• 2003

Smart UAV Development Program, one of the 21c Frontier R&D Program sponsored by MOST(Ministry of Science and Technology), was launched in 2002 As an air vehicle for the Smart UAV, CRW(Canard Rotor/wing) concept was one of the candidates compared in trade-off study. The CRW concept has not only been proven completely but its aerodynamic characteristics not known in detail yet. Two calculation methods were adopted in this study to obtain aerodynamic data for the CRW First method was the superpose DATCOM method which is capable of three lifting sufaces, and second one is the full Navier-Stokes computation around CRW configuration using overset grid method. Basic aerodynamic characteristics of the CRW configuration was analyzed and the minimum drag level with lift to drag ratio is presented. The peculiar flow characteristics around rotor/wing and hub were also examined and considered in the configuration design.

• 한국전산유체공학회:학술대회논문집
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• 2003.08a
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• pp.106-113
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• 2003

Smart UAV Development Program, one of the 21c Frontier R&D Program sponsored by MOST(Ministry of Science and Technology), was launched in 2002. As an air vehicle for the Smart UAV, CRW(Canard Rotor/Wing) concept was one of the candidates compared in trade-off study. The CRW concept has not only been proven completely but its aerodynamic characteristics not known in detail yet. Two calculation methods were adopted in this study to obtain aerodynamic data for the CRW. First method was the superpose DATCOM method which is capable of three lifting surfaces, and second one is the full Navier-Stokes computation around CRW configuration using overset grid method. Basic aerodynamic characteristics of the CRW configuration was analyzed and the minimum drag level with lift to drag ratio is presented. The peculiar flow characteristics around rotor/wing and hub were also examined and considered in the configuration design.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1572-1575
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• 2006

Water extract from Cnidii Rhizoma (CRW) was tested for colon cancer chemopreventive activity by measuring the induction of phase II detoxification enzyme activity [quinone reductase (QR) and glutathione S-transferase (GST)] and glutathion (GSH) levels and ornithine decarboxylase (ODC) activity in cultured human colorectal adenocarcinoma HT-29 cells. CRW inhibited cell proliferation in cultured HT-29 cells. CRW induced QR activity in a dose-dependent manner in a concentration range of 0.1${\sim}$5.0 $mg/m{\ell}$. GST activity was also induced with the treatment of CRW in HT-29 cells. In addition GSH levels was increased with CRW. CRW inhibited ODC activity, a key enzyme of polyamine biosynthesis, which is enhanced in tumor promotion. These results suggest that CRW has colon cancer chemopreventive activity by increasing phase II enzyme activity and GSH levels and inhibiting ODC activity in vitro.

• Korean Journal of Pharmacognosy
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• v.35 no.4 s.139
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• pp.283-287
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• 2004

The effect of water extract from Cnidii Rhizoma (CRW) on proliferation of human breast cancer cells, nitric oxide production, nitric oxide synthase expression, and ornithine decarboxylase activity was tested. CRW inhibited the growth of both estrogen-dependent MCF-7 and estrogen-independent MDA-MB-23I human breast cancer cells. Lipopolysaccharide-induced nitric oxide (NO) production was significantly reduced by CRW at the concentration of 0.5, 1.0 and 5.0 mg/ml. Expression of inducible nitric oxide synthase (iNOS) was also suppressed with the treatment of CRW in Raw 264.7 cells. CRW inhibited induction of ornithine decarboxylase by 12-0-tetradecanoylphorbol-13-acetate, a key enzyme of polyamine biosynthesis, which is enhanced in tumour promotion. Therefore, CRW is worth further investigation with respect to breast cancer chemoprevention or therapy.

• Korean Journal of Pharmacognosy
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• v.34 no.4 s.135
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• pp.297-302
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• 2003

Cnidii Rhizoma water extract (CRW) was tested for liver cancer chemopreventive potential by measuring the inhibition of phase I enzyme and benzo[a]pyrene-DNA adduct formation and induction of phase II detoxification enzymes. There was 17.0% inhibition in the activity of cytochrome P450 1A1 enzyme with the treatment of 150 mg/ml CRW. At concentration of 30 mg/ml CRW, the binding of $[^3H]B[a]P$ metablites to DNA of NCTC-clone 1469 cell was inhibited by 33.3%. CRW was potent inducer of quinone reductase (QR) and glutathione S-transferase (GST) activities in cultured murine hepatoma Hepalc1c7 cells. However, hepatic glutathione (GSH) level was not influenced by CRW. These findings suggest that CRW has chemopreventive potential of liver cancer by inhibiting cytochrome P450 1A1 activity and benzo[a]pyrene-DNA adduct formation and inducing QR and GST activities.

• Nuclear Engineering and Technology
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• v.50 no.8
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• pp.1266-1276
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• 2018

In this paper, three-dimensional neutronic calculations were performed in order to calculate the dependency of CRW on the temperature of fuel and moderator and the moderator void. Calculations were performed using the known MTR_PC computer codes in the core configuration 61 of TRR. The dependency of CRW on the fuel temperature in the range of $20-340^{\circ}C$ and the moderator temperature of each control rods were studied. Based on the positions of the control rods, the calculations were performed in three different cases, named case A, B and C. By the results, the worth of each control rods increases by increasing of the coolant temperature in all methods, however, the total CRW is somewhat independent of the fuel temperature. In addition, the results showed that the variation of CRW versus density depends on the positions of the control rods and the most change in CRW in the coolant temperature, $20-100^{\circ}C$ (279 pcm), belongs to SR4. Finally the effect of void on CRW was studied for different void fraction in coolant. The most worth change is about $2 for 40% void fraction related to SR1 and SR3 in case B. For 40% void fraction, the total CRW increases about $7.5, $6 and $7 in cases, A, B and C, respectively.

• Journal of the Korean Society of Propulsion Engineers
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• v.8 no.4
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• pp.76-83
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• 2004

A Propulsion System of the CRW(Canard Rotor Wing) type UAV(Unmanned Aerial Vehicle) was composed of the turbojet engine to generate the propulsive exhaust gas, and the duct system including main and rotary ducts, the nozzle subsystem including main and tip jet nozzle for three flight modes such as lift/landing mode, low speed transition flight mode and high speed forward flight mode. Transient simulation performance utilized the ICV (Inter-component volume) method and simulated using the SIMULINK. Transient performance analysis was performed on 3 cases. Fuel flow schedules to accelerate from Idle to maximum rotational speed were divided into the step increase of the most severe case and ramp increase cases to avoid the overshoot of turbine inlet temperature, and variations of thrust and the turbine inlet temperature were investigated in some transient analysis cases.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.10
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• pp.20-27
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• 2004

In this study, CFD analysis for 2D ellipse and 3D CRW UAV are performed. Furthermore, flow analysis around a hub connecting body and rotor is analyzed and a strategy to reduce the drag caused by the hub is sought. Also, the idea of fairing installation is confirmed by a wind tunnel test.

• Nuclear Engineering and Technology
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• v.41 no.3
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• pp.307-318
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• 2009

KAERI (Korea Atomic Energy Research Institute) has developed the GAMMA+ code for a thermo-fluid and safety analysis of a VHTR (Very High Temperature Gas-Cooled Reactor). A key safety issue of the VHTR design is to demonstrate its inherent safety features for an automatic reactor power trip and power stabilization during an anticipated transient without scram (ATWS) accident such as a loss of forced cooling by a trip of the helium circulator (LOFC) or a reactivity insertion by a control rod withdrawal (CRW). This paper intends to show the ATWS assessment capability of the GAMMA+ code which can simulate the reactor power response by solving the point-kinetic equations with six-group delayed neutrons, by considering the reactivity changes due to the effects of a core temperature variation, xenon transients, and reactivity insertions. The present benchmark calculations are performed by using the safety demonstration experiments of the 10 MW high temperature gas cooled-test module (HTR-10) in China. The calculation results of the power response transients and the solid core temperature behavior are compared with the experimental data of a LOFC ATWS test and two CRW ATWS tests by using a 1mk-control rod and a 5mk-control rod, respectively. The GAMMA+ code predicts the power response transients very well for the LOFC and CRW ATWS tests in HTR-10.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• v.y2005m4
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• pp.219-224
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• 2005

In order to investigate transient behaviour of the CRW(Canard Rotor Wing) type UAV(Uninhabited Aerial Vehicle) propulsion system during flight mode transition considering flow control valve operation, the propulsion system was modelled using SIMULINK commercial program. For transient simulation of the main engine system, the ICV(Inter-Component Volume) method was applied. The valve system is to control the gas flow of the rotary duct system and the main duct system, and the analysis was performed with an assumption that the total gas mass flow of the main engine is the same as summation of the rotary duct flow and the main duct flow, and with consideration of valve loss, flow rate and effective area in valve angle variation. The performance analysis was carried out during flight mode transitions from the rotary flight mode to the fixed wing flight mode and vice versa mode at altitude of 1Km, flight Mach number 0.1 and maximum engine rpm.