• Asian-Australasian Journal of Animal Sciences
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• v.21 no.11
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• pp.1629-1634
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• 2008

A trial was conducted to determine the effect of low crude protein (CP) diets with constant metabolizable energy to crude protein (ME:CP) ratio on growth, body composition and nutrient utilization of broiler chicks from 1 to 26 days of age. Four dietary treatments having four levels of CP and ME as 23, 22, 21 and 20% and 3,036, 2,904, 2,772 and 2,640 kcal/kg, respectively, were formulated and a ME:CP ratio of 132 was maintained in all the diets. Digestible lysine was maintained at 1.10 of the diet. A total of 1,760 day-old Hubbard broiler chicks were randomly divided into 16 experimental units and each diet was offered to four experimental units at random. Feed intake was increased (p<0.05) while weight gain and feed conversion ratio were adversely affected (p<0.05) when the diets with low CP and ME were fed to broilers. Total protein intake and total ME intake were linearly decreased (p<0.05) and protein efficiency ratio and energy efficiency ratio were lower (p<0.05) than in the chicks fed dietary regimen with 22% CP and 2,904 kcal/kg ME. The whole body analysis of the birds revealed that chicks fed the lowest dietary regimens retained less (p<0.05) nitrogen and more ether extract than chicks fed the control diet, however, body dry matter, total body ash and fat free body protein were not affected. Similarly, protein and energy utilization were also unaffected by the dietary treatments. In summary, chicks fed low CP diets with constant ME:CP ratio grew slower, used feed less efficiently and retained less protein and more body fat than chicks fed the control diet.

• Membrane Journal
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• v.11 no.4
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• pp.170-178
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• 2001

PVC microfiltration membrane was prepared by phase immersion method and applied to membrane bioreactor (MBR) contained activated sludge. The hydrophilicity of membrane and the pore size increase with the amount of additive(PVP) ducting the preparation of membrane. Permeation characteristics and the membrane fouling behavior were investigated by varying the internal environment in MBR using the prepared membranes. When there is a sludge bulking in MBR caused by microorganism, membrane fouling was accumulated. The cake layer resistance, R$_{c}$, of membrane increased in the order of CP-0 > CP-1.0 > CP-1.5. Rc increased up to 3.5~7 fold where the sludge bulking occurred in MBR. CP-1.5 seems to be appropriated membrane on the basis of the surface characteristics and the flux. The average flux of all the test membrane was 12(${\pm}$2) L/$m^2$hr whereas the COD removal efficiency was 98.8%. The ratio of bulking sludge and the type and the size of microorganism in operating MBR accelerate the membrane fouling and flux decline. It is concluded that the characteristic of membrane filtration depends on the hydrophilicity of membrane, the internal environment of MBR reactor and the growth factor of sludge.

• Molecules and Cells
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• v.42 no.4
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• pp.363-375
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• 2019

Fungal sectorization is a complex trait that is still not fully understood. The unique phenotypic changes in sporadic sectorization in mutants of CpBck1, a mitogen-activated protein kinase kinase kinase (MAPKKK) gene, and CpSlt2, a mitogen-activated protein kinase (MAPK) gene, in the cell wall integrity pathway of the chestnut blight fungus Cryphonectria parasitica have been previously studied. Although several environmental and physiological factors cause this sectoring phenotype, genetic variants can also impact this complex morphogenesis. Therefore, RNA sequencing analysis was employed to identify candidate genes associated with sectorization traits and understand the genetic mechanism of this phenotype. Transcriptomic analysis of CpBck1 and CpSlt2 mutants and their sectored progeny strains revealed a number of differentially expressed genes (DEGs) related to various cellular processes. Approximately 70% of DEGs were common between the wild-type and each of CpBck1 and CpSlt2 mutants, indicating that CpBck1 and CpSlt2 are components of the same MAPK pathway, but each component governs specific sets of genes. Functional description of the DEGs between the parental mutants and their sectored progenies revealed several key pathways, including the biosynthesis of secondary metabolites, translation, amino acid metabolism, and carbohydrate metabolism; among these, pathways for secondary metabolism and translation appeared to be the most common pathway. The results of this comparative study provide a better understanding of the genetic regulation of sector formation and suggest that complex several regulatory pathways result in interplays between secondary metabolites and morphogenesis.

• Bulletin of the Korean Chemical Society
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• v.17 no.11
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• pp.1040-1044
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• 1996

The catalytic dehydrocoupling of bis(1-sila-3-butyl)benzene, 1 by Cp2ZrCl2/Red-Al and Cp2ZrCl2/n-BuLi combination catalysts yielded a mixture of oily and solid polymers. While the catalytic dehydrocoupling of 2-phenyl-l,3-disilapropane, 2 by Cp2ZrCl2/n-BuLi combination catalyst produced a mixture of oily and solid polymers, the catalytic redistribution/dehydrocoupling of 2 by Cp2ZrCl2/Red-Al combination catalyst gave oily polymer. The dehydrocoupling of 1 and 2, unless the prior silane redistribution occurs, seems to initially produce a low-molecular-weight polymer, which then undergoes an extensive cross-linking reaction of backbone Si-H bonds, leading to an insoluble polymer.

• The Korea Journal of Herbology
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• v.23 no.2
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• pp.145-150
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• 2008

Objectives : SimJeok-Hwan (CP, Cardiotonic Pills) is the traditional remedy to treat patients with coronary arteriosclerosis, angina pectoris and hyperlipidemia. This study was designed to investigate the effects of CP on changes in serum cholesterol levels in hyperlipidemic rats. Methods : In this study, we investigated the effects of CP on changes in body weights, food and water uptake, fasting blood glucose, total cholesterols, HDL-cholesterol, and triglyceride in hyperlipidemic rats. Results : In our results, body weights of hyperlipidemic rats induced by high fat diet did not changed, and treatment with CP did not affect body weights in hyperlipidemic rats. For experimental period, food and water uptake in CP administered group were the same as those in hyperlipidemic control group. In this experiment, treatment with CP decreased total cholesterol and triglyceride in serum which elevated by high fat diet respectively. Conclusions : These results suggest that CP is useful to treat patients with disease related to hyperlipidemia because CP can decrease cholesterol in serum

• BMB Reports
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• v.52 no.11
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• pp.635-640
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• 2019

CpG-DNA triggers the proliferation and differentiation of B cells which results in the increased production of antibodies. The presence of bacteria-reactive IgM in normal serum was reported; however, the relevance of CpG-DNA with the production of bacteria-reactive IgM has not been investigated. Here, we proved the function of CpG-DNA for the production of bacteria-reactive IgM. CpG-DNA administration led to increased production of bacteria-reactive IgM both in the peritoneal fluid and serum through TLR9 signaling pathway. When we stimulated B cells with CpG-DNA, production of bacteria-reactive IgM was reproduced in vitro. We established a bacteria-reactive monoclonal IgM antibody using CpG-DNA stimulated-peritoneal B cells. The monoclonal IgM antibody enhanced the phagocytic activity of RAW 264.7 cells against S. aureus MW2 infection. Therefore, we suggest that CpG-DNA enhances the antibacterial activity of the immune system by triggering the production of bacteria-reactive IgM. We also suggest the possible application of the antibodies for the treatment of antibiotics-resistant bacterial infections.

• The Journal of Korean Medicine
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• v.42 no.2
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• pp.62-71
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• 2021

Objectives: This study was aimed to share the development process of the critical pathway (CP) for the treatment and management of stroke patients admitted to a Korean medicine hospital. Methods: A draft CP was prepared based on a review of relevant literature and medical records in the hospital, and its validity was reviewed by the in-hospital CP review committee. Each member evaluated all items in the CP on a 5-point Likert scale. Items with an average score of 3.5 or higher or an agreement rate of more than 80% were considered valid. In addition, free described opinions to improve the CP were also received from the review committee. Results: The horizontal axis of the CP was composed of a time domain, including 7 time points from hospitalization to discharge. The vertical axis was composed of 9 domains of medical practice. All items in the CP satisfied the validity criteria. The CP was revised, supplemented, and completed by reflecting the opinions of the committee. Conclusions: This CP will be taught to in-hospital users and will continue to be used with regular monitoring and a feedback plan. This study is expected to serve as a useful reference for standardizing the treatment process and delivering measures to improve the adequacy of Korean medicine treatment for stroke patients.

• The Korea Journal of Herbology
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• v.36 no.6
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• pp.9-16
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• 2021

Objectives : The researcher had investigated the efficacy of ginseng using Microneedle Therapy System (MTS) and confirmed the effect of ginseng Cold Process (CP) soap just before and after washing face. The purpose of this study was to find out what kind of effect appeared through a period of 6 weeks when environmental factors were involved using ginseng CP soap. Methods : The researcher selected 47 subjects, 37 as the experimental group and 10 as the control group. The researcher asked participants to wash their face twice a day in the morning and evening using ginseng CP soap, and the period was set for 6 weeks. The researcher had the people who selected as the control group use a commercially available foam cleanser. They performed a skin test before the start of the test, and the change status was continuously investigated 2 weeks, 4 weeks, and 6 weeks after using the soap. Results : In the case of T-zone oil, there was a significant decrease in the use of foam cleansing and ginseng CP soap, and in the case of pores and pigmentation, a significant decrease was observed only in the use of ginseng CP soap. In skin tone change, there was a significant effect in both the experimental group and the control group, but the significance was greatly increased in the case of ginseng CP soap compared to foam cleansing. Conclusions : Ginseng CP soap is considered to be a more suitable cleanser for skin care compared to foam cleansing.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.237-240
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• 2008

The objective of this study is to evaluate the seismic performance of the low-rise RC apartment buildings having piloties at ground level by using nonlinear static analysis with regards to the maximum considered and design earthquakes in Korea. To do this, the target displacement at roof was estimated according to FEMA356 (or ASCE/SEI-41), and the deformations of the critical members were compared with the failure criteria of Life Safety(LS) and Collapse Prevention(CP) given in FEMA356. The conclusions are as follows: (1) columns satisfy criteria of LS and CP, but (2) the shear wall in the longitudinal direction failed to satisfy those of both LS and CP while those in the transverse direction satisfy that of LS, but failed that of CP.

• Journal of the Korean Society for Precision Engineering
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• v.34 no.2
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• pp.77-81
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• 2017

CP (Commercially Pure) titanium has been widely used in various industries such as in energy plants and bio-materials because of an excellent corrosion resistance and its non-toxicity to the human body. But there are limitations for usage as structural materials due to low strength. The tensile properties of CP titanium could be improved by microstructure refinement such as in a SPD (Severe Plastic Deformation) process. However, high strengthening of CP titanium wire is impossible by SPD processes like ECAP (Equal Channel Angular Pressing), HPT (High-Pressure Torsion), and the ARB (Accumulative Roll Bonding) process. The study purposes are to increase the strength of CP titanium wire by optimization of the cold drawing process and the harmonization with mechanical properties by heat treatments for the next forming process. The optimization process was investigated with regard to the design of drawing dies and the reduction ratio of cross sections. The elongations of high strength CP titanium were controlled by heat treatment.