• Title/Summary/Keyword: CNR1

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RESVERATROL APPEARS TO AFFECT IN A DIFFERENT WAY PRIMARY VS. FIXED DNA DAMAGE INDUCED BY $H_2O_2$ IN MAMMALIAN CELLS IN VITRO

  • Salvia, Rosella-De;Fabiola Festa;Ruggero Ricordy;Paolo Perticone;Cristina Mucc;Renata Cozzi
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.108-109
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    • 2001
  • Resveratrol (3, 5, 4'-trihydroxystilbene) is a naturally occuring molecule, synthesized by several plants in response to different stresses. Recently many studies performed in human and mammalian cells demonstrated the involment of resveratrol in the modulation of several biological processes (inhibition of lipidic peroxidation, platelet aggregation, estrogenic activity). It has also been found to possess scavenging and antioxidant properties (1).(omitted)

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FT-IR Study of Dopant-wool Interactions During PPy Deposition

  • Varesano Alessio;Aluigi Annalisa;Tonin Claudio;Ferrero Franco
    • Fibers and Polymers
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    • v.7 no.2
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    • pp.105-111
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    • 2006
  • Coating the fibre surface by in situ oxidative chemical polymerisation of polypyrrole (using $FeCl_3$ as oxidant) is a readily industrial applicable way to give electrical properties to wool with good ageing stability [1], although pre-treatments are required to avoid damage of the cuticle surface due to the acidic condition of the process. FT-IR and EDX analysis reveal that organic sulphonates and sulphates, used as dopants, are absorbed by wool, while chlorine ions are preferably embedded on the polypyrrole layer. The resulting electrical conductivity seems mainly due to the presence of chlorine as counter-ion of polypyrrole; nevertheless, the presence of arylsulphonate in the polymerisation bath increases the electrical conductivity of the coating layer.

APPLICATION OF STABLE EMULSIONS TO LIPASE IMMOBILISED MEMBRANE REACTORS FOR KINETIC RESOLUTION OF RACEMIC ESTERS

  • Giorno, Lidietta;Na, Li;Drioli, Enrico
    • Proceedings of the Membrane Society of Korea Conference
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    • 2003.07a
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    • pp.65-68
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    • 2003
  • The paper discusses the use of stable emulsion, prepared by membrane emulsification technology, to improve the enantiocatalytic performance of immobilised lipase in multiphasic membrane reactors. The production of optical pure (S)-naproxen from racemic naproxen methyl ester has been used as model reaction system. The enzyme was immobilised in the sponge layer (shell side) of capillary polyamide membrane with 50 kDa cut-off, The O/W emulsion, containing the substrate in the organic dispersed phase, was fed to the enzyme membrane reactor from shell-to-lumen. The results evidenced that lipase maintained stable activity during all the operation time (more than 250 hours), showing an enantiomeric excess (96 $\pm$2%) comparable to the free enzyme (98 $\pm$ 1%) and much higher compared to similar lipase-loaded membrane reactors used in two-separate phase systems (90%). The study showed that immobilised enzymes can achieve high stability as well as high catalytic activity and enantioselectivity.

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Performance Analysis of QPSK and QDPSK Signals with Diversity Reception and Coding Techniques in Fading Plus Impulsive Noise Environments (임펄스 잡음과 페이딩이 함께 존재하는 환경에서 다이버시티 수신 기법과 부호화 기법을 채용하는 QPSK 및 QDPSK 신호의 성능 해석)

  • Leem, Kill-Yong;Cho, Sung-Joon;Lee, Jin
    • The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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    • v.5 no.4
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    • pp.3-17
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    • 1994
  • The error probability of QPSK and DPSK signals with diversity reception technique in m-distribution fading plus impulsive noise environments has been derived and the error probability is evaluated and compared with that in Gaussian noise environment. The error performance degrades as impulsive noise becomes strong and degree of degradation of signal performance in QDPSK signal is larger than that in QPSK signal. The diversity reception technique can improve the error performance not only in fading plus Gaussian noise environment but in fading plus impulsive noise environment. When diversity reception technique is used, the improvement of error performance attains about 10dB to 15dB in terms of CNR as compared with that in non diversity reception. Among diversity techniques the maximal ratio combining is must effective. When diversity reception and coding techniques are used together in impulsive noise plus Rayleigh fading environments, the improvement of error performance attains about 12dB to 15dB in terms of CNR as compared with that of only diversity reception technique case and the improvement of error perform- ance in RS coding attains about 2dB in terms of CNR as compared with that of BCH coding case.

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Usefulness of DECT Application for Compensation of Image Contrast Difference According to CT Contrast Agent Density (CT 조영제 농도에 따른 영상 대조도 차 보상을 위한 DECT 적용의 유용성)

  • Hyeon-Ju Kim
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.417-422
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    • 2023
  • In this study, normal saline was diluted with the contrast medium at a certain ratio for the purpose of reducing the image quality poor and side effects caused by the contrast medium during CT examination. At this time, by finding the energy level of DECT that can compensate for the decrease in contrast of the image according to the degree of dilution, the usefulness of applying DECT for compensating the difference in image contrast was investigated through comparative analysis by applying SNR, CNR, and SSIM. As a result, when a dilution ratio of 4 (contrast medium): 6 (normal saline) and the energy level of DECT of 65 keV were applied, the contrast difference was the most similar to that when using the undiluted contrast medium. At this time, SNR was 813.71 ± 37.6, CNR was the highest at 921.87 ± 17.1, and SSIM index was measured at 0.851, which is the most similar to 1. The results of this study are meaningful in providing basic information for finding the appropriate dilution rate and energy level for each examination site through future clinical studies. It is believed that it can be reduced.

Evaluation of TlBr semiconductor detector in gamma camera imaging: Monte Carlo simulation study

  • Youngjin Lee;Chanrok Park
    • Nuclear Engineering and Technology
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    • v.54 no.12
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    • pp.4652-4659
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    • 2022
  • Among the detector materials available at room temperature, thallium bromide (TlBr), which has a relatively high atomic number and density, is widely used for gamma camera imaging. This study aimed to verify the usefulness of TlBr through quantitative evaluation by modeling detectors of various compound types using Monte Carlo simulations. The Geant4 application for tomographic emission was used for simulation, and detectors based on cadmium zinc telluride and cadmium telluride materials were selected as a comparison group. A pixel-matched parallel-hole collimator with proven excellent performance was modeled, and phantoms used for quality control in nuclear medicine were used. The signal-to-noise ratio (SNR), contrast to noise ratio (CNR), sensitivity, and full width at half maximum (FWHM) were used for quantitative analysis to evaluate the image quality. The SNR, CNR, sensitivity, and FWHM for the TlBr detector material were approximately 1.05, 1.04, 1.41, and 1.02 times, respectively, higher than those of the other detector materials. The SNR, CNR and sensitivity increased with increasing detector thickness, but the spatial resolution in terms of FWHM decreased. Thus, we demonstrated the feasibility and possibility of using the TlBr detector material in comparison with commercial detector materials.

T1-weighted MR Imaging of the Neonatal Brain at 3.0 Tesla: Comparison of Spin Echo, Fast Inversion Recovery, and Magnetization-prepared Three Dimensional Gradient Echo Techniques (3T 자기공명영상 장비에서 신생아 뇌의 T1 강조 영상: 스핀에코, 고속 역전회복, 자기화 삼차원 경사에코기법의 비교)

  • Jeong, Jee-Young;Yoo, So-Young;Jang, Kyung-Mi;Eo, Hong;Lee, Jung-Hee;Kim, Ji-Hye
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.2
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    • pp.87-94
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    • 2007
  • Purpose: The purpose of this study was to evaluate the usefulness of fast inversion recovery (FIR) and magnetization-prepared three dimensional gradient echo sequence (3D GRE) T1-weighted sequences for neonatal brain imaging compared with spin echo (SE) sequence in a 3T MR unit. Materials and Methods: T1-weighted axial SE, FIR and 3D GRE sequences were evaluated from 3T brain MR imaging in 20 neonates. The signal-to-noise ratio (SNR) of different tissues was measured and contrast-to-noise ratios (CNR) were determined and compared in each of the sequences. Visual analysis was carried out by grading gray-white matter differentiation, myelination, and artifacts. The Wilcoxon signed ranked test was used for evaluation of the statistical significance of CNR differences between the sequences. Results: Among the three sequences, the 3D GRE had the best SNRs. CNRs obtained with FIR and 3D GRE were statistically superior to those obtained with SE; these CNRs were better on the 3D GRE compared to the FIR. Gray to white matter differentiation and myelination were better delineated on the FIR and 3D GRE than the SE. However, motion artifacts were more commonly observed on the 3D GRE and flow-related artifacts of vessels were frequently seen on the FIR. Conclusion: FIR and 3D GRE are valuable alternative T1-weighted sequences to conventional SE imaging of the neonatal brain at 3T providing superior image quality.

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Susceptibility Weighted Image for Stem Cell Tracking in Rat Photothrombotic Infarction (흰쥐 광 혈전 뇌경색 모델에서 줄기세포 추적을 위한 자화강조영상)

  • Ha, Bon-Chul;Lim, Cheong-Hwan
    • The Journal of the Korea Contents Association
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    • v.10 no.8
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    • pp.249-256
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    • 2010
  • To the detect of SPIO-labelled hMSC, in vitro study on various cell concentration and in vivo molecular magnetic resonance imaging(MRI) technique using T2, $T2^*$ and SWI are compared with pathology. Cell concentration was $1.56{\times}10^4$, $3.13{\times}10^4$, $6.25{\times}10^4$, $1.25{\times}10^5$, $2.5{\times}10^5$, $5{\times}10^5\;cells/m{\ell}$ and for control $5{\times}10^5\cells/m{\ell}$. MRI technique using T2, $T^2$ and SWI. Photothrombotic infarction was located 2.5mm from bregma right, posterior. Cell injected through the tail vein of rat for 8 rats. MRI performed pre injection and post injection of 1, 3, 7 and 14days and sacrifice for pathology. MRI analysed on quantitatively. In vitro result, SWI was highest CNR as compared with $T2^*WI$, T2WI and $2.5{\times}10^5\;cells/m{\ell}$ cell concentration. In vivo result among the T2WI, $T2^WI$, SWI, T2WI is highest CNR between normal and infarction. CNR in normal-SPIO and infarction-SPIO is high score in SWI. Therefore, T2WI is good distinguish between normal and infarction, SWI are well detect SPIO-labelled hMSC from normal and infarction. Nowaday, SWI are mostly used on hemorrhage, calcification etc. in clinically, but for the future, stem cell therapy is commonly application at all disease which is good observing tool for SPIO-labelled stem cells.

Development of a Quality Check Algorithm for the WISE Pulsed Doppler Wind Lidar (WISE 펄스 도플러 윈드라이다 품질관리 알고리즘 개발)

  • Park, Moon-Soo;Choi, Min-Hyeok
    • Atmosphere
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    • v.26 no.3
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    • pp.461-471
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    • 2016
  • A quality check algorithm for the Weather Information Service Engine pulsed Doppler wind lidar is developed from a view point of spatial and temporal consistencies of observed wind speed. Threshold values for quality check are determined by statistical analysis on the standard deviation of 3-component of wind speed obtained by a wind lidar, and the vertical gradient of horizontal wind speed obtained by a radiosonde system. The algorithm includes carrier-to-noise ratio (CNR) check, data availability check, and vertical gradient of horizontal wind speed check. That is, data sets whose CNR is less than -29 dB, data availability is less than 90%, or vertical gradient of horizontal wind speed is less than $-0.028s^{-1}$ or larger than $0.032s^{-1}$ are classified as 'doubtful', and flagged. The developed quality check algorithm is applied to data obtained at Bucheon station for the period from 1 to 30 September 2015. It is found that the number of 'doubtful' data shows maxima around 2000 m high, but the ratio of 'doubtful' to height-total data increases with increasing height due to atmospheric boundary height, cloud, or rainfall, etc. It is also found that the quality check by data availability is more effective than those by carrier to noise ratio or vertical gradient of horizontal wind speed to remove an erroneous noise data.

Evaluation of Validity Thyroid Scintigraphy Using Parallel Hole Collimator (갑상샘 신티그래피 검사 시 평행다공형 조준기 적용의 유효성 평가)

  • Su-Young Park;Ji-Youn Kim;Sung-Min Ahn
    • Journal of the Korean Society of Radiology
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    • v.18 no.1
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    • pp.27-36
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    • 2024
  • In this study, When acquisition thyroid scintigraphy images, a parallel hole collimator was applied, and the difference from the pinhole collimator was quantitatively analyzed under each image acquisition condition. Visual size, resolution, sensitivity, signal to noise ratio (SNR), and contrast to noise ratio (CNR) were evaluated using thyroid phantom and point source. When comparing visual size, it was confirmed that an image similar to the size of the pinhole collimator could be obtained only when a magnification ratio of about 2.00 to 2.09 times when applying a parallel hole collimator. There was no tendency in FWHM(mm) measurement using a point source, and sensitivity was high in the parallel hole collimator. SNR and CNR were high when using a low magnification ratio, matrix size of 128×128, and a parallel hole collimator. In images of similar size to the naked eye, when the matrix size was the same, both SNR and CNR were high in the pinhole collimator. Therefore, when performing a thyroid scintigraphy test, if appropriate conditions are set according to the situation of each hospital and a parallel hole collimator is applied, it can be a good option in terms of equipment utilization and work efficiency.