• Title/Summary/Keyword: CNB

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Clinical Features and Surgical Outcome of Congenital Neuroblastoma of Adrenal Gland (부신 기원의 선천성 신경모세포종의 치료 경험)

  • Park, Hyo-Jun;Moon, Suk-Bae;Seo, Jeong-Meen;Lee, Suk-Koo
    • Advances in pediatric surgery
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    • v.15 no.1
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    • pp.38-43
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    • 2009
  • With the widespread use of the obstetrical ultrasound, identification of a fetal suprarenal mass becomes more common. Most of these masses prove to be congenital neuroblastomas (CNB) postnatally. However, the diagnosis is often confused with other benign lesions and the post-natal management remains controversial. The medical records of 13 patients that underwent primary surgical excision for an antenatally detected adrenal CNB, between January 1995 and April 2009, were reviewed retrospectively. The clinical, radiological, surgical, and pathological data on the suprarenal mass were collected. Staging evaluation was performed after histological confirmation of the CNB. Most of the CNBs were stage I (N=11), with 1 stage IV and 1 stage IV-S. Four patients (3 stage I and 1 stage IV-S) had N-myc gene amplification. The stage I patients were cured by surgery alone, and stage IV patients underwent 9 cycles of adjuvant chemotherapy and currently have no evidence of disease after 39 months of follow-up. The patient with stage IV-S is currently receiving chemotherapy. There were no post-operative complications. For early diagnosis and treatment, surgical excision should be considered as the primary therapy for an adrenal CNB detected before birth. The surgery can be safely performed during the neonatal period and provides a cure in most cases. Surgical diagnosis and treatment of CNB is recommended in neonatal period.

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Information System for Blind People (시각 장애인의 보행에 관한 연구)

  • Hahn, Sang-Il;Kim, Jong-Su;Cha, Hyung-Tai
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2009.11a
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    • pp.383-386
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    • 2009
  • 대부분의 시각 장애인은 보행을 위해 흰 지팡이 및 안내견의 도움을 받는다. 일반적으로 사용되는 흰 지팡이는 주변 정보의 수집에 한계가 있으며 안내견은 고도의 훈련비용에 따른 비용의 문제점이 있어 그 수가 매우 제한적이다. 따라서 본 논문에서는 시각 장애인의 보행을 위한 시스템을 제한하고자 한다. 제안하는 시스템은 다음과 같다. 먼저 카메라를 이용하여 보행에 필요한 점자유도블럭을 검출한 후 검출된 점자유도블럭의 상태를 HRTF를 이용한 입체음향으로 소리를 전달하여 시각장애인이 안전한 보행을 할 수 있도록 하였다.

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Fine Needle Aspiration Cytology vs. Core Needle Biopsy for Thyroid Nodules: A Prospective, Experimental Study Using Surgical Specimen (갑상선 결절에 대한 세침 흡인 세포 검사와 중심부 바늘 생검의 비교: 수술 검체를 기반으로 한 전향적, 실험적 비교 연구)

  • Hyuk Kwon;Jandee Lee;Soon Won Hong;Hyeong Ju Kwon;Jin Young Kwak;Jung Hyun Yoon
    • Journal of the Korean Society of Radiology
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    • v.83 no.3
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    • pp.645-657
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    • 2022
  • Purpose To evaluate and compare the diagnostic outcomes of ultrasonography (US)-guided fine needle aspiration (FNA) and core needle biopsy (CNB) performed on the same thyroid nodule using a surgical specimen for direct comparison. Materials and Methods We included 89 thyroid nodules from 88 patients from February 2015 to January 2016. The inclusion criterion was thyroid nodules measuring ≥ 20 mm (mean size: 40.0 ± 15.3 mm). Immediately after surgical resection, FNA and subsequent CNB were performed on the surgical specimen under US guidance. FNA and CNB cytopathologic results on the specimen were compared with the surgical diagnosis. Results Among the 89 nodules, 30 were malignant and 59 were benign. Significantly higher inconclusive rates were seen in FNA for malignant than benign nodules (80.0% vs. 39.0%, p < 0.001). For CNB, conclusive and inconclusive rates did not differ between benign and malignant nodules (p = 0.796). Higher inconclusive rates were seen for FNA among cancers regardless of US features, and in the subgroup of size ≥ 40 mm (62.5% vs. 22.9%, p = 0.028). Eleven cancers were diagnosed with CNB (36.7%, 11/30), while none was diagnosed using FNA. Conclusion In this experimental study using surgical specimens, CNB showed a potential to provide improved diagnostic sensitivity for thyroid cancer, especially when a conclusive diagnosis is limited with FNA.

A Study on the Brassiere Wearing Evaluation for Augmentation of Mammaplasty Patients (시판 유방 확대 수술 환자용 브래지어의 착의 평가)

  • Yi, Kyong-Hwa;Nam, Young-Ran
    • Journal of the Korean Society of Clothing and Textiles
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    • v.42 no.5
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    • pp.737-752
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    • 2018
  • The frequency of breast augmentation surgery continues to increase annually; however, the method of follow-up care varies from hospital to hospital. In particular, many different types of post-operative bras are available in the market. This study evaluated the wearing comfort of various commercial bras that were worn immediately after breast enlargement surgery prior to the manufacture of the bra. According to interviews of medical professionals and market research, five types of brassiere were selected and evaluated by wearing satisfaction, functional performance, and an external appearance test for 6 subjects with breast augmentation surgery. The evaluation questionnaires were based on a 5 point Likert scale with data analyzed using SPSS 20.0. The study results revealed that the bra with the highest degree of satisfaction was CNB (without bra cup) type. However, the use of CNB type showed dissatisfaction in functional evaluation questions regarding breast shaking and material & tactile sensation. In the future, it is necessary to develop a new post-operative brassiere based on a CNB type bra that showed the best evaluation. However, it is also necessary to identify the merits of the other four experimental bras and reflect these advantages.

Functional Screening of Plant Genes Suppressed Salt Sensitive Phenotype of Calcineurin Deficient Mutant through Yeast Complementation Analysis (애기장대의 염해 저항성 관련 유전자의 기능적 선별)

  • Moon, Seok-Jun;Park, Soo-Kwon;Hwang, Un-Ha;Lee, Jong-Hee;Han, Sang-Ik;Nam, Min-Hee;Park, Dong-Soo;Shin, Dongjin
    • Journal of Life Science
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    • v.23 no.1
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    • pp.1-7
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    • 2013
  • Understanding salt tolerance mechanisms is important for the increase of crop yields, and so, several screening approaches were developed to identify plant genes which are involved in salt tolerance of plants. Here, we transformed the Arabidopsis cDNA library into a salt-sensitive calcineurin (CaN)-deficient ($cnb{\Delta}$) yeast mutant and isolated the colonies which can suppress salt-sensitive phenotype of $cnb{\Delta}$ mutant. Through this functional complementation screen, a total of 34 colonies functionally suppressed the salt-sensitive phenotype of $cnb{\Delta}$ yeast cells, and sequencing analysis revealed that these are 9 genes, including CaS, AtSUMO1 and AtHB-12. Among these genes, the ectopic expression of CaS gene increased salt tolerance in yeast, and CaS transcript was up-regulated under high salinity conditions. CaS-antisense transgenic plants showed reduced root elongation under 100 mM NaCl treatment compared to the wild type plant, which survived under 150 mM NaCl treatment, whereas CaS-antisense transgenic plant leaves turned yellow under 150 mM NaCl treatment. These results indicate that the expression of CaS gene is important for stress tolerance in yeast and plants.

The Role of Ultrasound Guided Core Needle Biopsy in Thyroid Nodule (갑상선 결절에서 초음파 유도하 중심생검의 역할)

  • Ryu, Yoon-Jong;Ahn, Soon-Hyun
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.1-4
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    • 2015
  • Fine needle aspiration cytology(FNAC) holds a main role in assessing thyroid nodules. But nonnegligible rate of thyroid cytology is reported as uncertain, indeterminate or inadequate for diagnosis. Recently, the microhistologic evaluation by core needle biopsy(CNB) under ultrasound sonographical guidance has been reported to show high accuracy for the diagnose of thyroid nodules. Aim of this review was to furnish the state of the art of this topic by summarizing previous published data about indication, diagnostic performance, and complication of CNB in thyroid lesions compared with FNAC

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