• Journal of Oriental Neuropsychiatry
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• v.33 no.3
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• pp.301-316
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• 2022

Objectives: To compare Korean medicine (KM) and traditional Chinese medicine (TCM) psychotherapy for anxiety. Methods: Databases including MEDLINE (via PubMed), EMBASE (via Elsevier), Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, and Oriental Medicine Advanced Searching Integrated System were comprehensively searched. Prospective clinical studies on KM or TCM psychotherapy for patients with anxiety disorder or individuals with elevated anxiety levels published up to August 3, 2022 were reviewed. Psychotherapy was divided into counselling, art therapy, and meditation according to its characteristics. Results: A total of 12 clinical studies were reviewed, including nine randomized controlled trials. The most common disorder investigated was post-traumatic stress disorder. Ten studies used TCM psychotherapy and two used KM psychotherapy. As for differences between TCM psychotherapy and KM psychotherapy, TCM psychotherapy utilized pattern identification in the procedure more actively than KM psychotherapy. In addition, some TCM studies have attempted to directly converge Western psychotherapy (i.e., hypnosis) and Eastern psychotherapy (i.e., Taoin qigong therapy). In the case of KM psychotherapy, there was an attempt to incorporate psychotherapy with Sasang constitutional medicine. Reported effects of TCM psychotherapy and KM psychotherapy on anxiety were positive. Conclusions: Research status of KM psychotherapy and TCM psychotherapy for anxiety was investigated, revealing some of their characteristics, commonalities, and differences. Findings of this review have the potential to provide a clue to the development of conventional KM psychotherapy and new medical technology for KM psychotherapy.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.67.2-68
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• 2003

A rice cultivar, Taebaegbyeo, is highly resistant to rice blast and moderately resistant to bacterial leaf blight (BLB) caused by Magnaporthe grisea and Xanthomonas oryzae pv. oryzae, respectively. To study the rice disease resistance mechanism, we generated rice deletion M3 mutants by gamma-ray irradiation. Blast and BLB responses of 16,000 M3 mutants were screened by inoculating mixtures of 4 races (KJ-201, H-1113a, KI-313, KI-409) of M. grisea and 3 Korean races of X. oryzae pv. oryzae. We selected so far 21 M3 mutants of Taebaegbyeo showing high susceptibility to the diseases. One of the mutants, KCT-6417, was susceptible to KI-1113a race of M. grisea, suggesting the deletion of a race-specific blast resistance gene in the mutant. To isolate rice genes involved in blast resistance and defense response, we take a PCR-based suppression subtractive hybridization approach using cDNAs of blast-inoculated wild type and the KCT-6417 as a tester and a driver, respectively. Genes specifically expressed in the wild type will be presented. The selected genes would give us a clue to understand mechanism for the race specific resistance and defense responses against M. grisea H-1113a in Taebaegbyeo.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.2
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• pp.1-9
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• 2023

Objectives : This study used a network pharmacology approach to analyze the treatment mechanisms of Yijin-tang on Meniere's disease, and comparative analysis the treatment mechanisms of drugs recommended in the Meniere's disease treatment guidelines. Methods : We collected information on the recommended drugs from the Meniere's disease treatment guidelines and their target proteins were screened via the STITCH database. The intersection targets were obtained through Venny 2.1.0. Gene Ontology(GO) analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway analysis were performed using ClueGO. Results : The 7 proteins(TNF, CASP9, PARP1, CCL2, CFTR, NOS2, NOS1) were associated with both Yijin-tang and Meniere's disease related genes. The 10 proteins(AQP2, KCNE1, AQP1, AVP, ACE, HRH1, HRH3, NOS1, CA1, CFTR) were associated with both the recommended drugs in the guidelines and Meniere's disease related genes. The 2 proteins(CFTR, NOS1) were common across all three groups. Further, GO/KEGG pathway analysis of the collected proteins revealed that the common mechanisms of action between Yijin-tang and the recommended drugs in the guidelines were related to pathways involving immune dysfunction and disturbances in lymphatic fluid homeostasis. In addition, the recommended drugs in the guidelines appeared to act through mechanisms that improve blood flow through vasodilation. Conclusions : Pharmacological network analysis can help to explain the treatment mechanisms of Yijin-tang on Meniere's disease.

• Nuclear Engineering and Technology
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• v.55 no.9
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• pp.3150-3163
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• 2023

To improve the performance of blanket: maximizing the tritium breeding rate (TBR) for tritium self-sufficiency, and minimizing the Dose of backplate for radiation protection, most previous studies are based on manual corrections to adjust the blanket structure to achieve optimization design, but it is difficult to find an optimal structure and tends to be trapped by local optimizations as it involves multiphysics field design, which is also inefficient and time-consuming process. The artificial intelligence (AI) maybe is a potential method for the optimization design of the blanket. So, this paper aims to develop an intelligent optimization method based on an improved multi-objective NSGA-III algorithm and an adaptive BP neural network to solve these problems mentioned above. This method has been applied on optimizing the radial arrangement of a conceptual design of CFETR HCSB blanket. Finally, a series of optimal radial arrangements are obtained under the constraints that the temperature of each component of the blanket does not exceed the limit and the radial length remains unchanged, the efficiency of the blanket optimization design is significantly improved. This study will provide a clue and inspiration for the application of artificial intelligence technology in the optimization design of blanket.

• The Journal of Korean-Japanese National Studies
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• no.34
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• pp.5-40
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• 2018

This paper is to take note of national, social and economic movement, social & economic publicness of religion surrounding Yeonggwang, Joennam around 1910s. At first I would like to look at this period because regional society was in the middle of change of large transition before and after Japan's forced occupation of Korea in 1910s and March 1st Independence Movement in 1919. In particular we focus on spatially Yeonggwang in Joennam because this area is not only called as advent area of Buddhism earlier but also is unique regional culture and ideological topology where Donghak, Protestantism, Catholic, Institute of Won Buddhism and etc. Through casting light upon the above, it is expected to offer one clue for the question of internalizing value to be sought for in the national and social and economic movement by Korean religion around 1910 and public goods in the strategy and tactics to be selected and further publicness and practice lying in their awareness and behavior. In particular it is thought to have advanced the accumulation of case study of Yeonggwang in Joennam with representative 'place-ness' related to this. Along with this it is considered that our challenge is to restore and casting light again on common foundation of existence shape and publicness of various religions in the middle of national and social movement and economic movement in Yeonggwang of Joennam area. In other words, we expect that religions will continue individual efforts and common practices to urge social justice for historic and public value based on common good encompassing historic value, in other words, individual responsibility and social justice among social and economic conditions originated from Japanese colonial era.

• BMB Reports
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• v.56 no.2
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• pp.96-101
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• 2023

Particulate matter is an air pollutant composed of various components, and has adverse effects on the human body. Particulate matter is known to induce cell death by generating an imbalance in the antioxidant system; however, the underlying mechanism has not been elucidated. In the present study, we demonstrated the cytotoxic effects of the size and composition of particulate matter on small intestine cells. We found that particulate matter 2.5 (PM_2.5) with extraction ion (EI) components (PM_2.5 EI), is more cytotoxic than PM containing only polycyclic aromatic hydrocarbons (PAHs). Additionally, PM-induced cell death is characteristic of ferroptosis, and includes iron accumulation, lipid peroxidation, and reactive oxygen species (ROS) generation. Furthermore, ferroptosis inhibitor as liproxstatin-1 and iron-chelator as deferiprone attenuated cell mortality, lipid peroxidation, iron accumulation, and ROS production after PM_2.5 EI treatment in human small intestinal cells. These results suggest that PM_2.5 EI may increase ferroptotic-cell death by iron accumulation and ROS generation, and offer a potential therapeutic clue for inflammatory bowel diseases in human small intestinal cells.

• Journal of the Institute of Convergence Signal Processing
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• v.23 no.4
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• pp.249-255
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• 2022

Potholes are an important clue to the structural defects of asphalt pavement and cause many casualties and property damage. Therefore, accurate pothole detection is an important task in road surface maintenance. Many machine learning technologies are being introduced for pothole detection, and data preprocessing is required to increase the efficiency of deep learning models. In this paper, we propose a preprocessing method that emphasizes important textures and shapes in pothole datasets. The proposed preprocessing method uses intensity transformation to reduce unnecessary elements of the road and emphasize the texture and shape of the pothole. In addition, the feature of the porthole is detected using Superpixel and Sobel edge detection. Through performance comparison between the proposed preprocessing method and the existing preprocessing method, it is shown that the proposed preprocessing method is a more effective method than the existing method in detecting potholes.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.140-147
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• 2009

Purpose: This study was conducted to investigate the relationship between primary dysmenorrhea. Methods: Intensity of dysmenorrhea was evaluated by scoring system of Andersch and Milsom. Anger state, trait, expression of the patients suffering from dysmenorrhea was measured by STAXI-K. And each value was analyzed by ANOVA testm as to intensity of dysmenorrhea, student t test as to existence of dysmenorrhea. Results: The numerical value of anger expression in the primary dysmenorrhea existent group was significantly higher than that in the primary dysmenorrhea non-existent group. There were significant differences among the numerical value of anger expression in the groups classified as intensity of primary dysmenorrhea, the value of three positive group() was significantly higher than that of negative group(-). Conclusion: This study showed the relationship between anger expression and primary dysmenorrhea. But there was no clue to find out their causal relationship, because this study was cross-sectional. So further study will be needed to prove the causality between them. And more precise scale has to been developed to evaluate various type of anger accurately.

• Journal of Engineering Education Research
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• v.25 no.6
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• pp.93-102
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• 2022

Due to COVID-19, all activities in society are emphasized non-face-to-face, and the educational environment is changing without exception. Looking at the results of the survey after conducting non-face-to-face education, there was a lot of rejection of non-face-to-face practical education. The biggest reason was that instructors were not familiar with the non-face-to-face education method, and feedback was not smooth during or after education. In particular, software practice education was not easy to share the software development environment, but communication and feedback on class contents and tasks were important. In particular, if face-to-face and non-face-to-face are alternately variable, it is not easy for practical education to be consistently connected. Even if non-face-to-face hands-on education is changed to face-to-face hands-on education, we will present a plan to use a data sharing system such as question-and-answer, assignment, practice content, and board content so that it can proceed smoothly. This study presents an efficient software education process that can provide learners with a software integrated practice environment based on a shared server, question-and-answer between instructors and learners, and share feedback on tasks. For the verification of the presented process, the effectiveness was confirmed through the survey results by applying the face-to-face/non-face-to-face education process to 220 trainees for 30 months in software education classes such as A university hands-on education, B company new employees, and ICT education courses.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.33 no.2
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• pp.61-70
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• 2023

This paper examines the way of thinking and limitations of physicists regarding the phenomenon of superconductivity and outlines how room-temperature and ambient-pressure superconductors can be developed through the statistical thermodynamic background of the liquid state theory. In hypothesis, the number of electron states should be limited by confining them to a state close to one-Dimension. Simultaneously, the electron-electron interactions should be frequent enough for the electrons to have liquid-like properties. As an example of implementing the hypothesis, our team reports the development of room-temperature and ambient-pressure superconductivity of a material named LK-99 (superconducting compound name developed in the research), whose structure was revealed through numerous experiments with a clue found by chance. Moreover, we summarize the theoretical and experimental basis for the characteristics and discovery of the world's first superconducting material surpassing the critical temperature of 97℃ at atmospheric pressure.