• 제목/요약/키워드: CLUE

검색결과 699건 처리시간 0.03초

Visualizing Geographical Contexts in Social Networks

  • Lee, Yang-Won;Kim, Hyung-Joo
    • Spatial Information Research
    • /
    • 제14권4호
    • /
    • pp.391-401
    • /
    • 2006
  • 이 논문에서는 지리적 표현이 보강된 사회네트워크 모형을 제시하고, 이 모형을 통해 사회네트워크의 지리적 맥락을 시각화하는 3D 웹서비스를 구현한다. 이 연구에서 제안하는 사회네트워크 그래프 개선의 핵심요소는 (i) 네트워크 노드들의 상호작용 강도 및 공간적 인접성이 반영된 '지리적 가중치가 부여된 중심화 지수' 그리고 (ii) 이러한 중심화 지수를 3차원 심볼을 이용하여 표현함과 동시에 네트워크 노드들을 단계 구분도와 중첩하여 시각화하는 '지도와 결합된 사회네트워크 그래프'이다 개선된 사회네트워크 그래프는 X3D (Extensible 3D)를 이용하여 구현하였으며, 시도간 R&D 협력의 사례분석을 통해 그 적용가능성이 확인되었다. 이 논문에서 제시하는 방법론은 사회네트워크에 내재하는 공간적 집중화의 경향 등 기존의 네트워크 분석에서 간과되었던 사회네트워크의 지리적 맥락에 대한 시각적 단서를 제공한다.

  • PDF

개의 질병에 사용된 동아시아 전통의학 처방 연구 (Orthodox Oriental Medicine in East Asia used for Canine Diseases)

  • 박상영;오준호
    • 혜화의학회지
    • /
    • 제22권1호
    • /
    • pp.57-70
    • /
    • 2013
  • Objective: Today, the public concern for 'Companion Animal" as a family member is ever increasing. Accordingly, the cases of traditional veterinary medicine treatment targeting a companion animal has been increasing, but the traditional records in literature about this have hardly ever been introduced to academic circles. Hereupon, this writing is intending to collect the prescriptions, which were once used for treating canine diseases, in order to report them to academic circles first. Method: This writing recorded the information about canine diseases and their treatment from the books related to the orthodox oriental medicine in East Asia, and analyzed their meanings. Result: Intial records about canine diseases are found in East Asian traditional medicine books including "Bonchoseubyu"(741), "Ilwhajajegaboncho"(unidentifiable period), "Jeungryuboncho"(1082), etc. The disease perceived by humans at that time was "gwa"(a boil) which is a kind of skin ailments. In addition, these medicine books show that people at that time concentrated on the value of use of a dog as meat rather than a pain of a dog's diseases. "Hwalsujaju"(1873)which was established during the Qing Dynasty leaves the most abundant data on canine diseases. This book perceived a dog as a precious existence watching over human housing and property, according to which, canine diseases and treatment methods are subdivided. The prescriptions for a dog's disease in our country are identifiable only in "Jeungbodanbangshinpyeon"(1913)과 "Bijeongmanbyeongtongchibeop"(1933). These books include the prescriptions not only for a dog's disease but also for a disease of a cow, horse, sheep, chicken, and pig, etc. which are familiar to us. Conclusion: The prescriptions used for a dog in East Asia were different from those for people. It was found that they used a medicine noticeably for external application for easy treatment, and in case of the use of an internal medicine, they adopted a method of getting dogs to take a medicine mixed with rice or porridge for dogs. Such a clue will be applied to the traditional- medicine-based treatment of a companion animal for the time to come.

Inhibition of Monoamine Oxidase B by Cigarette Smoke Constituents

  • Lim, Heung-Bin;Sohn, Hyug-Ok;Lee, Young-Gu;Moon, Ja-Young;Kang, Young-Kook;Kim, Yong-Ha;Lee, Un-Chul;Lee, Dong-Wook
    • 한국연초학회지
    • /
    • 제19권2호
    • /
    • pp.136-144
    • /
    • 1997
  • Cigarette smoking is known to suppress both 1-methy14-phenyl-155,Ltetrahydropy-ridine (MPTP)-induced parkinsonism and idiopathic Parkinson's disease (PD). However, the precise mechanism underlying its protective action against PD is not clearly elucidated yet. In order to find possible clue on the mechanism of protective action of smoking, we investigated the inhibitory effect of cigarette smoke components on rat brain mitochondria1 monoamine oxidase B (MAO-B), responsible enzyme for the activation of MPTP to its toxic metabolitesr and identified the components having an inhibitory potency on this enzyme from cigarette smoke. Total 31 eligible constituents including nicotine were selected from cigarette smoke condensates via solvents partitioning and silica gel chromatographic separation, and inhibitory potencies of 19 components on MAO-B were determined. Hydroquinone and methylcatechol, the phenolic components, showed the strongest inhibitory potencies on MAO-B activity in the components tested. 3,4-Dihydroxybenzylamino, myosmine and indole in basic fracton, eugenol in phenolic fraction, and farnesol in neutral fraction also inhibited the enzyme activity dose-dependently. Among tobacco alkaloids tested only myosmine was effective for the inhibition of this enzyme. These results suggest that the decrease in MAO-B activity by such components derived from cigarette smoke seems to be related to the suppression of MPTP-induced neurotoxicity and to the less incidence of Parkinson's disease in smokers than in nonsmokers.

  • PDF

마이크로터널링으로 인한 활주로 기층의 전단 강성의 변화 : 크로스흘 시험과 SASW 실험에 의한 평가 (Evaluation of Subgrade Stiffness after Microtunnelling Operations at JFK Airport by Crosshole and SASW Tests)

  • 조성호
    • 한국지반공학회지:지반
    • /
    • 제14권2호
    • /
    • pp.67-78
    • /
    • 1998
  • 마이크로터널링은 비교적 연약한 사질토 지반을 통과하는 소규모의 터널을 시공할 때 적용하는 공법으로, 터널 시작 위치에서 일련의 짧은 원형 콘크리트 관을 유압으로 밀어서 전구간을 관통하는 공법이다. 미국 뉴욕의 JFK공항의 활주로에서는 활주로 하부를 통과하는 전력구의 설치를 위하여 이러한 마이l터널링 공법을 시도하였다. 마이크로터널링 공법에서는 콘크리트관을 전진시키기 위해 강력한 유압으로 벤토나이트를 분출하는데, 이로 인하여 활주로 하부의 지반이 교란될 가능성이 있었기에 본 연구에서는 터널시공으로 인한 교란의 정도를 평가하기 위하여 SASW 기법과 크로스흘 시험을 수행하였다. 구조물 비파괴 건전도 기법인 SASW 기법으로는 활주로 기층 부위의 지반강성 변화 정도를 평가하였고, 크로스흘 시험으로는 활주로 인접 지반의 깊이별 5파속도 변화를 조사하였다. 또한, JFK 공항 부지에서 결정한 5파 속도-N 치의 부지특유 관계식을 통하여 5파 속도를 N치로 변환함으로써 지반강성의 변화를 지반강도 변화의 측면으로도 지반교란의 정도를 파악하였다.

  • PDF

온라인 후기를 통한 맞춤 웨딩한복의 디자인 고찰 2016년~2017년 (A study on custom Hanbok design through on-line review - From 2016 To 2017 -)

  • 류경옥
    • 한국의상디자인학회지
    • /
    • 제20권3호
    • /
    • pp.27-32
    • /
    • 2018
  • Hanbok is a our own history and tradition and is an icon of Korean history and culture. Today, the costumes are moving around the world fashion trend due to the development of mass media and internet at the same time. This is an important clue to marketing activities and can be used for predictive analysis. Although Hanbok is changing little by little every year, research on the trend of Hanbok is rare. This study analyzed the results of searching for 'Hanbok' as a keyword in Portal Site Naver and posting a customized purchase of Hanbok for marriage between 2016 and 2017. The analysis was based on analyzing the photos uploaded, and analyzing purchase reason in the On-line review. Most buyer of Hanbok purchased for prepare marriage. The choice of a customized hanbok is mostly to search online or to use the fair. The most important factor in choosing a custom Hanbok that appeared in online reviews is color and then price. The color of the jacket is mostly light color and the off-white color is the most used and the long skirt such as the pink system, the chorale system and the red system, and it can be seen that the pink skirt is overwhelmingly large. In the design of Hanbok, The sleeves were straight and narrow, and the length was the chest line. The collar were enlarged and widened. 고름 used the sole color instead of the jacket and skirt color, and it was narrow not long. skirt's pleats was wide, and designed to overlap with double color of the fabric.

Looking for Direct Evidence of Triggered Star Formation: Gas Kinematics

  • Lim, Beomdu;Sung, Hwankyung;Lee, Jae Joon;Oh, Heeyoung;Kim, Hwihyun;Hwang, Narae;Park, Byeong-Gon
    • 천문학회보
    • /
    • 제41권2호
    • /
    • pp.54.1-54.1
    • /
    • 2016
  • Stellar wind and radiation pressure from massive stars can trigger the formation of new generation of stars. The sequential age distribution of stars, the morphology of cometary globules, and bright-rimmed clouds have been accepted as evidence of triggered star formation. However, these characteristics do not necessarily suggest that new generation of stars are formed by the feedback of massive stars. In order to search for any physical connection between star forming events, we have initiated a study of gas and stellar kinematics in NGC 1893, where two prominent cometary nebulae are facing toward O-type stars. The spectra of gas and stars in optical and near-infrared (NIR) wavelength are obtained with Hectochelle on the 6.5m MMT and Immersion GRating INfrared Spectrograph on the 2.7m Harlan J. Smith Telescope at McDonald observatory. In this study, the radial velocity field of gas across the cluster is investigated using $H{\alpha}$ and [N II] ${\lambda}$ 6584 emission lines, and that of the cometary nebula Sim 130 is also probed using 1-0 S(1) transition line of $H_2$. We report a distinctive velocity field of the cometary nebulae and many ro-vibrational transitions of $H_2$ even at high energy levels in the NIR spectra. These properties indicate the interaction between the cometary nebulae and O-type stars, and this fact can be a clue to triggered star formation in NGC 1893.

  • PDF

Sol-Gel법에 의한 $Li_2O-Al_2O_3-TiO_2-SiO_2$계 다공성 결정화 유리의 제조 : (I) Sol-Gel 방법에 의한 $Li_2O-Al_2O_3-TiO_2-SiO_2$계 다공성 겔체의 제조 (Preparation of Glass-Ceramics in $Li_2O-Al_2O_3-TiO_2-SiO_2$ System by Sol-Gel Technique : (I) Preparation of Porous Monolithic Gel in $Li_2O-Al_2O_3-TiO_2-SiO_2$ System by Sol-Gel Method)

  • 조훈성;양중식;권창오;이현호
    • 한국세라믹학회지
    • /
    • 제30권7호
    • /
    • pp.535-542
    • /
    • 1993
  • It was investigated in this study that a preparation method, activation energy, surface area, pore volume, pore size distribution and DTA analysis of the dry gel in process of producing monolithic porous gel in Li2O-Al2O3-TiO2-SiO2 system by the sol-gel technique using metal alkoxides. Activation energy for gellation according to the variation of water concentration and the kind of catalysts ranged from 10 to 20kcal/mole. Monolithic dry gels were prepared after drying at 9$0^{\circ}C$ when the amount of water for gellation was 4~8 times more than the stoichiometric amount, that was necessary for the full hydrolysis of the mixed metal alkoxide. The specific surface area, the pore volume, the average pore radius of the dried gel at 18$0^{\circ}C$ according to the various kinds of catalyst were about 348~734$m^2$/g, 0.35~0.70ml/g and 10~35$\AA$, respectively. It showed that the dry gels were porous body. As a result ofthe analysis of DTA, it was confirmed that the exothermaic peaks at 715$^{\circ}C$ and 77$0^{\circ}C$ was clue to the crystallization of dried gel.

  • PDF

수용성 EPCR에 의한 활성화된 단백질 C의 항염증 작용에 관한 연구 (Effect of Soluble EPCR on the Anti-Inflammatory Effects by Activated Protein C)

  • 배종섭;박문기;박상욱
    • Korean Chemical Engineering Research
    • /
    • 제47권4호
    • /
    • pp.501-505
    • /
    • 2009
  • 본 논문에서는 혈관내피세포에서 활성화된 단백질 C(Activated Protein C, APC)의 항염증 작용에서 수용성 EPCR(Soluble Endothelial Protein C Receptor, sEPCR)의 효과를 관찰하였다. sEPCR은 APC가 매개하는 항염증 작용에 있어 내피세포막의 보호효과를 저해하고, 혈관내피세포에 대한 백혈구의 부착저해 효과를 억제하며, 혈관내피세포를 관통하는 백혈구의 이동을 저해하는 효과를 억제한다. 그리고 흥미롭게도 sEPCR은 내피세포에서 TNF-alpha에 의한 세포부착단백질의 발현을 억제하는 APC의 기전을 저해함으로써 APC가 가지는 항염증 효과를 억제한다. 이것은 APC의 Gla 도메인이 내피세포의 수용체인 EPCR에 결합할 수 있는 부위에 sEPCR이 상호작용함으로써 더 이상 APC이 세포막에 존재하는 EPCR과 결합을 못함으로써 APC의 항염증 작용은 억제되는 것을 의미한다. 이 결과는 향후 중증 패혈증 및 염증질환을 효과적으로 치료할 수 있는 신약개발에 중요한 단서를 제공할 것이고 내피세포에서 아직 명확하게 밝혀지지 않은 APC의 항염증 작용의 기전을 밝히는 데 좋은 정보를 제공할 것이다.

사례기반추론기법을 적용한 침해사고 프로파일링 시스템 (Applying CBR algorithm for cyber infringement profiling system)

  • 한미란;김덕진;김휘강
    • 정보보호학회논문지
    • /
    • 제23권6호
    • /
    • pp.1069-1086
    • /
    • 2013
  • 최근에 발생하는 웹 사이트 해킹은 기업의 이미지와 평판에 악영향을 끼치는 큰 위협이 되고 있다. 이러한 웹 사이트 변조 행위는 해커의 정치적인 동기나 성향을 반영하기도 하므로, 행위에 대한 분석은 해커나 해커 그룹을 추적하기 위한 결정적인 단서를 제공할 수 있다. 웹 사이트에 남겨진 특정한 메시지나 사진, 음악 등의 흔적들은 해커를 추적하기 위한 단서를 제공할 수 있고, 인코딩 방법과 해커가 남긴 메시지에 사용된 폰트, 트위터나 페이스북 같은 해커의 SNS ID 또한 해커의 정보를 추적하는데 도움을 준다. 본 논문에서는 zone-h.org의 웹 해킹 사례들로부터 특성들을 추출하고, CBR(Case-Based Reasoning) 알고리즘을 적용하여 침해사고 프로파일링 시스템을 구현하였다. 해커의 흔적과 습관에 관한 분석 및 연구는 추후 사이버 수사에 있어 공격 의도를 파악하고 그에 따른 대응책을 마련하는 데 있어 IDSS(Investigation Detection Support System)로써 중요한 역할을 기대 할 수 있으리라 본다.

조선후기(朝鮮後期) 상한(傷寒) 연구(硏究)의 일면(一面) - 조선후기(朝鮮後期) 상한(傷寒) 연구서(硏究書) "상한경험방요촬(傷寒經驗方要撮)"의 구성과 내용 - (Composition and Contents of the Monograph on Theory of Cold Damage - "Sanghankyeongheombangyochal"(傷寒經驗方要撮) in the Late Joseon Dynasty)

  • 오준호;박상영;김현구;권오민
    • 한국한의학연구원논문집
    • /
    • 제18권1호
    • /
    • pp.25-34
    • /
    • 2012
  • Objective : This study was carried out with focus on written by Joh, Taek-seung (曺澤承) and Joh, Byeong-who(曺秉矦) in the relation of father and son in 1933. This book is a medical book including rare data, which has never been reported to academic circles all this while. Method : First, this study looked into the authors of this book and its history of publication. Further, this study analyzed the composition and contents of this book. Lastly, this study summed up the meaning of this book from the standpoint of medical history. Result : The authors were Confucian doctors who were active in the latter era of the Joseon Dynasty and also in the period of Japanese colonial rule. They lived in Haenam district of Jeonlanam-do, and cured its neighboring local residents while studying. They published the book of by putting together their own medical experiences. The authors suggested their remedial prescription according to gender and age whereas Zhang Zhongjing(張仲景) suggested the remedial prescription according to Six-Meridian Pattern Identification & Syndrome Differentiation(六經辨證). In addition, the authors of gave weight to the relationship with internal damage. Additionally, the authors not only thought much of the relationship between internal damage and external damage but also thought of the weakness and strength of the healthy qi, and the new and the old of a disease as an important clue to medical treatment. It seems that such contents was influenced by (東醫寶鑑). Conclusion : shows the results of the research on which was spontaneously conducted in Joseon.