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Preliminary Imaging Analysis for Enhanced Intestinal Uptake of Non-soluble Polystyrene Microspheres in the Presence of Oleic Acid using Rat Intestine

  • Tran, Huyen Thi Thanh;Tran, Phuong Ha Lien;Tran, Thao Truong-Dinh;Lee, Kyung-Ho;Lee, Beom-Jin
    • Journal of Pharmaceutical Investigation
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    • v.39 no.3
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    • pp.155-159
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    • 2009
  • In vitro intestinal uptake of non-soluble polystyrene microspheres (NPMS) was visualized with and without oleic acid using a fluorescence microscopy. Fluorescent polystyrene latex microspheres with 1${\mu}$m larger size were used as models for nonspecifically absorbed nonbiodegradable particulates. The NPMS could not penetrate the enterocytes but a few NPMS could be penetrated via Peyer's patches. When the oleic acid was mixed with NPMS, the transporting efficiency of NPMS through enterocytes as well as Peyer's patches was significantly enhanced. The modification of the intestinal membrane permeability and surface feature of the NPMS in the presence of oleic acid might be a clue to the transport of NSPM although the detailed mechanism is still under investigation.

A Measurement Error Correction Algorithm of Road Structure for Traveling Vehicle's Fluctuation Using VF Modeling (VF 모델링을 이용한 주행차량의 진동에 대한 도로 계측오차 보정 알고리듬)

  • Jeong, Yong-Bae;Kim, Jung-Hyun;Seo, Kyung-Ho;Kim, Tae-Hyo
    • Proceedings of the Korea Institute of Convergence Signal Processing
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    • 2005.11a
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    • pp.190-200
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    • 2005
  • In this paper, the image modelling of road's lane markings is established using view frustum(VF) modeling. This algorithm also involve the real time processing of the 3D position coordinate and the distance data from the camera to the points on the 3D world coordinate by the camera calibration. In order to reduce their measurement error, an useful algorithm for which analyze the geometric variations clue to traveling vehicle's fluctuation using VF model is proposed. In experiments, without correction, for instance, the $0.4^{\circ}$ of pitching rotation gives the error of $0.4^{\sim}0.6m$ at the distance of 10m, but the more far distance cause exponentially the more error. We confirmed that this algorithm can be reduced less than 0.1m of error at the same condition.

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A study on the Six-surface theory in Shang-Han-Lun - Focussed on the Ke-qin's Shang-Han-Lun-Yi - ("상한론(傷寒論)" 육경지면설(六經地面說)에 관한 연구(硏究))

  • Lee, Sang-Hyup
    • Journal of Korean Medical classics
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    • v.26 no.3
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    • pp.33-52
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    • 2013
  • Objective : Zhang Zhong-jing's Shang-Han-Lun is based on Six-channels system(六經) to classified a disease, but the notion of this seems to be a very various angles. Among them, Ke-qin(柯琴)'s Six-surface theory(六經地面說) is very clearly explained the notion of Six-channels system(六經) and it provide crucial clue to understanding a Shang-Han-Lun Method : I will try to describe the Six-surface theory(六經地面說) through the Ke-qin's Shang-Han-Lun-Yi(傷寒論翼). At the core of this paper, The diaphragm is the most important criterion to understand a Six-channels system(六經), and it is based on the human body to divided into Yin-Yang(陰陽). Result : Ke-qin's Six-surface theory(六經地面說) is connected with Meridian system(經絡), Viscera and Bowels(臟腑), and their functions. It is the concept of comprehensive to including those related were grouped into the surface. Conclusion : Six-surface(六經地面) is far beyond the simple concept of Meridian, and it include organization of pathology concepts carrying up to what happens on the human body caused by disease. We can see that Zhong-jing's(仲景) medical treatment from syndrome differentiation(辨證) is associated with a holism(整體觀).

Korean medical treatments for metabolic syndrome accompanied with diabetes: a case report (당뇨를 동반한 대사증후군 환자의 한의학적 치료 1례)

  • Kim, Yang-Seob;Yim, Yun-Kyoung
    • Journal of Haehwa Medicine
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    • v.23 no.1
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    • pp.149-156
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    • 2014
  • A 30 year old female patient suffering from metabolic syndrome, who was diagnosed with hyperglycemia, dyslipidemia and diabetes 2 years ago, was treated with Traditional Korean Medicine including acupuncture, herbal medicine and tuina for one month. After the treatments, her fasting blood sugar level was remarkably decreased (from $304mg/d{\ell}$ to $74mg/d{\ell}$). And the levels of blood lipids were decreased as well ; the level of TG was decreased from $330mg/d{\ell}$ to $90mg/d{\ell}$, the level of total cholesterol was decreased from $217mg/d{\ell}$ to $111mg/d{\ell}$, the level of LDL was decreased from $119mg/d{\ell}$ to $53mg/d{\ell}$). The waist circumference was also decreased from 96 cm to 90.5 cm. Korean Medical therapies may bring a new clue for the treatment of metabolic syndrome with diabetes.

A Study on the Brand Space Characteristics from the Aspect of Social Psychology - Focused on the Advance Research through Analyzing the Theoretical Methodology of Realism and Relationship - (사회심리학 기반의 브랜드공간 특성 연구 - 실재론적·관계론적 분석을 통한 선행연구를 중심으로 -)

  • Shin, Hye-Won
    • Korean Institute of Interior Design Journal
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    • v.22 no.6
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    • pp.49-57
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    • 2013
  • This study aims to provide direction for the brand goals approaching and analyzing previous studies in social psycholog y perspective, focusing on man and society relationship. 526 preceding 'brand space' associated papers from 1992 to 2012 were collected and analyzed them by year, by space and by theme utilizing the realism methodology, the theor etical relationship methodology. The numbers of the study for 'brand space' had increased gradually from 2003 to 2010 then climbed vertically and the most common study was about place, that shows there is a relationship between variou s social phenomena and human psychology. For the thematic analysis, 'Social psychological components of the brand' based on social psychology was used for analyzing the cognitive aspects, the relational aspects, and the attitudinal aspects. The most common study was the study of the cognitive aspects, and relational aspects, and lastly the attitud inal aspects in order. The strategy was the most common research for the brand associated study. The ultimate point of the strategy is to get 'attitude'. From social psychology perspective, there is a cycle in the minds of consumers, 'Identification', 'Internalization', 'Conformity' and 'Compliance'. Structure of these relationships can provide a clue that consumers' attitude lead the consumers' action.

A Study for the Restoration of Hong Dae-Yong Honsangui - Focusing on the structure and operating mechanism -

  • Lee, Yong Sam;Kim, Sang Hyuk;Park, Je Hoon
    • Journal of Astronomy and Space Sciences
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    • v.30 no.3
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    • pp.187-192
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    • 2013
  • Honsangui (celestial globe) which is a water-hammering method astronomical clock is recorded in "Juhaesuyong" which is Volume VI of supplement from "Damheonseo", written by Hong Dae-Yong (1731~1783). We made out the conceptual design of Hong Dae-Yong's Honsangui through the study on its structure and working mechanism. Honsangui consist of three rings and two layers, the structure of rings which correspond to outer layer is similar to his own Tongcheonui (armillary sphere) which is a kind of armillary sphere. Honsang sphere which correspond to inner layer depicts constellations and milky way and two beads hang on it as Sun and Moon respectively for realize the celestial motion. Tongcheonui is operated by the pendulum power but Honsangui is operated by water-hammering method mechanism. This Honsangui's working mechanism is the traditional way of Joseon and it was simplified the working mechanism of Shui y$\ddot{u}$n i hsiang t'ai which is a representative astronomical clock of China. This record of Honsangui is the only historical record about the water-hammering method working mechanism of Joseon Era and it provide the study of water-hammering method mechanism with a vital clue.

Nursing Students' Clinical Judgment Skills in Simulation: Using Tanner's Clinical Judgment Model (시뮬레이션에서의 간호대학생의 임상적 판단 기술 분석: Tanner의 Clinical Judgment Model을 적용하여)

  • Kim, Eun Jung
    • The Journal of Korean Academic Society of Nursing Education
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    • v.20 no.2
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    • pp.212-222
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    • 2014
  • Purpose: The purpose of this study was to evaluate the nursing students' clinical judgment skills in simulation using Tanner's Clinical Judgment Model. Method: Forty-five teams of a total 93 nursing students participated in a post-operative patient care scenario using human patient simulator. Data were collected from students' responses in scenario and guided reflective journaling according to the framework of Tanner's model which comprised noticing, interpreting, responding, and reflecting on response. Data were analyzed using descriptive statistics. Results: The students' responses of the situation were in accordance with the goals of scenario, i.e. relieving patient' pain and preventing pulmonary complications. However, most of students needed clinical cues and focused on a given clue to solve the issues. They were lack of ability to collect additional information as well as connect the relevant clues in simulated clinical situation. Conclusion: The nursing students have difficulty in what they notice, how they interpret finding, and respond appropriately to the situation. The simulation training using Tanner's model could provide faculty and nursing students with an effective teaching and learning strategy to develop the clinical judgment skills.

A Study on the Context of Affordance in Smart-phone Interface (스마트폰 인터페이스의 어포던스 맥락에 관한 연구)

  • Kim, Hyung Woo
    • Journal of Korea Multimedia Society
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    • v.18 no.5
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    • pp.663-670
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    • 2015
  • In this study, I have researched the theories about Gibson's real affordance and Norman's perceived affordance which are central fact of affordance, And I have examined the context of affordance in smart-phone interface which was consist of affordance and signifier with viewpoint of amalgamation of Gibson & Norman. The results of this study are as follows; The first, Gibson's real affordance is a physical space in ubiquitous environment that interact through the behavioral space is composed with physical space and electronic space. Norman's perceived affordance is mediated to electronic space and signifier makes a behaviroal space which provide the clue of interaction. The second, signifier can be categorized into visceral, behavioral and reflective signifier based on three brain actions which are visceral, behavior, and reflection. Through the categorization, we can grasp that behavioral and reflective signifies generate visceral signifier. The third, the context of affordance in smart-phone has the structure of circulation. The structure of circulation is as follows: Real affordance makes the perceived affordance, the perceive affordance makes the signifiers and the signifiers make new real affordance. This study could provide the theoretical basis for using signifier in smart-phone interface design.

Affordance in Multimedia environment with emphasis on Mobile Games (멀티미디어 환경에서의 어포던스에 관한 연구 -모바일 게임을 중심으로-)

  • Kim, H.J.;You, Si-Cheon
    • Smart Media Journal
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    • v.1 no.1
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    • pp.72-79
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    • 2012
  • This paper deals with usability issue that is one of the important user interface issues in multimedia environment. The purpose of this study is to define the concept of affordance in multimedia environment, which is adapted from product design fields and to seek development plan of more efficient interface and assurance interaction with interface. As a result, it is useful that the concept of affordance in multimedia design is applied as a 'useful clue for performing task.' Furthermore, it is possible that the concept of affordance is used as one of the improving methods of usability for users in multimedia environment.

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DEBRIS DISKS EXPLORED BY AKARI AND IRSF

  • Kiriyama, Y.;Ishihara, D.;Nagayama, T.;Kaneda, H.;Oyabu, S.;Onaka, T.;Fujiwara, H.
    • Publications of The Korean Astronomical Society
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    • v.27 no.4
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    • pp.181-182
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    • 2012
  • Using the AKARI mid-infrared all-sky survey catalogue, we are searching for debris disks which are important objects as an observational clue to on-going planetary system formation. Debris disk candidates are selected through a significant excess of the measured flux over the predicted flux for the stellar photospheric emission at $18{\mu}m$. The fluxes were originally estimated based on the near-infrared spectral energy distributions (SEDs) of central stars constructed from the 2MASS J-, H-, and Ks-band fluxes. However, we found that in many cases the 2MASS photometry has large errors due to saturation in the central part of a star image. Therefore we performed follow-up observations with the IRSF 1.4m near-infrared telescope in South Africa to obtain accurate fluxes in the J-, H-, and Ks-bands. As a result, we have succeeded in improving the SEDs of the central stars. This improvement of the SEDs allows us to make more reliable selection of the candidates.