• Title/Summary/Keyword: CGD

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Changes in cultural characteristics and biological activities of amaranth during fermentation (발효시간에 따른 아마란스 발효물의 배양특성 및 생리활성)

  • Lee, Rea-Hyun;Yang, Su-Jin;Hong, Joo-Heon
    • Food Science and Preservation
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    • v.23 no.4
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    • pp.568-575
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    • 2016
  • Bacillus amyloliquefaciens CGD3 was used as a starter for fermentation of amaranth and cultural characteristics and biological activities of amaranth were investigated. The viable cells in fermented amaranth was 4.54~8.01 log CFU/mL during 96 hr of fermentation period. Protease activities of amaranth showed the highest by 36.7 unit/mL after 72 hr of fermentation. The total phenolic and flavonoid contents of amaranth increased with fermentation time while its total sugar content decreased. The total protein content was the highest in amaranth fermented for 96 hr (0.25 mg/g). The DPPH scavenging activities, FRAP (ferric reducing antioxidant power), and reducing power of amaranth were highest in amaranth fermented for 72 hr, showing 84.46%, $551.91{\mu}M$, and 2.74, respectively. ACE (angiotensin converting enzyme) and ${\alpha}$-Glucosidase inhibition rates increased with fermentation time and showed the highest after 72 hr.

The Enlarged Sorting Algorithm of Tri - Point Comparsion Method for Bang - Bang Optimal Control (Bang - Bang 최적제어(最適制御)에 대한 3 점비교(点比校) 색출법(索出法)의 확장 알고리즘)

  • Kim, Joo-Hong;Jeong, In-Guk;Oh, Jun-Nam;Kim, Jin-Wan;Gho, Han-Jun
    • Proceedings of the KIEE Conference
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    • 1988.11a
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    • pp.64-67
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    • 1988
  • This paper proposes a algorithm to obtain a time-varing system parameters for the optimal controller. The proposed algorithm is enlarged from tile optimal sorting algorithm. It applies to Bang-Bang control and compares with CGD Method. We confirm that the proposed algorithm is excellent.

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The transition of dominant noise source for different CMOS process with Cgd consideration (Cgd 성분을 포함한 공정별 주요 잡음원 천이 과정 연구)

  • Koo, Minsuk
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.5
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    • pp.682-685
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    • 2020
  • In this paper, we analyze the dominant noise source of conventional inductively degenerated common-source (CS) cascode low noise amplifier (LNA) when width and gate length of stacked transistors vary. Analytical MOSFET and its noise model are used to estimate the contributions of noise sources. All parameters are based on measured data of 60nm, 90nm and 130nm CMOS devices. Based on the noise analysis for different frequencies and device parameters including process nodes, the dominant noise source can be analyzed to optimize noise figure on the configuration. We verified analytically that the intuctively degenerated CS topology can not sustain its benefits in noise above a certain operation frequency of LNA over different process nodes.

Computer Technologies as A Method to Create A Contemporary Ex-Libris

  • Romanenkova, Julia;Bratus, Ivan;Varyvonchyk, Anastasia;Sharikov, Denis;Karpenko, Olga;Tkachuk, Olena
    • International Journal of Computer Science & Network Security
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    • v.22 no.6
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    • pp.332-338
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    • 2022
  • The article is dedicated to the phenomenon of modern ex-libris created with the help of computer graphics. The process of evolution in the use of various techniques of book plate creating is analyzed, the role of computer technologies in the popularization of the modern book plate is emphasized. The debatable nature of the issue of the danger of displacement, replacement of traditional techniques of printed graphics with computer technologies is emphasized. Computer graphics are positioned as an effective way to popularize the Ukrainian ex-libris in the foreign art space. The characteristic features of the Ukrainian computer ex-libris are highlighted, a parallel with the book plate created with the help of computer graphics by masters of other countries (Belgium, China, the Netherlands, Poland, Turkey) is drawn

Occupational Lung Diseases: Spectrum of Common Imaging Manifestations

  • Alexander W. Matyga;Lydia Chelala;Jonathan H. Chung
    • Korean Journal of Radiology
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    • v.24 no.8
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    • pp.795-806
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    • 2023
  • Occupational lung diseases (OLD) are a group of preventable conditions caused by noxious inhalation exposure in the workplace. Workers in various industries are at a higher risk of developing OLD. Despite regulations contributing to a decreased incidence, OLD remain among the most frequently diagnosed work-related conditions, contributing to significant morbidity and mortality. A multidisciplinary discussion (MDD) is necessary for a timely diagnosis. Imaging, particularly computed tomography, plays a central role in diagnosing OLD and excluding other inhalational lung diseases. OLD can be broadly classified into fibrotic and non-fibrotic forms. Imaging reflects variable degrees of inflammation and fibrosis involving the airways, parenchyma, and pleura. Common manifestations include classical pneumoconioses, chronic granulomatous diseases (CGD), and small and large airway diseases. Imaging is influenced by the type of inciting exposure. The findings of airway disease may be subtle or solely uncovered upon expiration. High-resolution chest CT, including expiratory-phase imaging, should be performed in all patients with suspected OLD. Radiologists should familiarize themselves with these imaging features to improve diagnostic accuracy.

A Study on An Integrated GEO/TES with Geothermal Heat Exchanger and Thermal Ice Storage (지중열 교환기와 빙축열조(Thermal Ice Storage)를 연계시킨 통합 지중열-빙축열조 시스템(Integrated GEO/TES))

  • Lohrenz ED.;Hahn Jeongsang;Han Hyuk Sang;Hahn Chan;Kim Hyoung Soo
    • Economic and Environmental Geology
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    • v.38 no.6 s.175
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    • pp.717-729
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    • 2005
  • Peak cooling load of large buildings is generally greater than their peak heating load. Internal and solar heat gains are used fur selection of adquate equipment in large building in cold winter climate like Canada and even Korea. The cost of geothermal heat exchanger to meet the cooling loads can increase the initial cost of ground source heat pump system to the extend less costly conventional system often chosen. Thermal ice storage system has been used for many years in Korea to reduce chiller capacity and shift Peak electrical time and demand. A distribution system designed to take advantage of heat extracted from the ice, and use of geothermal loop (geothermal heat exchanger) to heat as an alternate heat source and sink is well known to provide many benifits. The use of thermal energy storage (TES) reduces the heat pump capacity and peak cooling load needed in large building by as much as 40 to $60\%$ with less mechanical equipment and less space for mechanical room. Additionally TES can reduce the size and cost of the geothermal loop by 1/3 to 1/4 compared to ground coupled heat pump system that is designed to meet the peak heating and cooling load and also can eliminate difficuties of geothermal loop installation such as space requirements and thermal conditions of soil and rock at the urban area.

Clinical Manifestation of Children with Failure to Thrive (Failure to Thrive를 주소로 내원한 환아들의 임상상)

  • Moon, Jeong-Hee;Kim, Ji-Young;Beck, Nam-Sun
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.68-74
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    • 2000
  • Purpose: This study was to investigate the clinical manifestations of FTT in children. Methods: From March 1997 to July 1999, clinical observations were made on patients with FTT who had visited to Samsung Medical Center. Detailed histories and through physical examinations were taken, and when suspected organic FTT, basic laboratory studies were done. Results: Upon the review of medical records, we investigated the clinical manifestations of 74 children, aged 1 month and 13 year 1 month. The causes of FTT were composed of either physiologic (47.8%) or pathologic (52.2%) ones. Among the physiologic FTT, were there familial short stature (FSS, 14.5%), intrauterine growth retardation (IUGR, 14.5%), constitutional growth delay (CGD, 11.6%), idiosyncrasy and prematurity. Among pathologic causes, neurologic disorders (20%) are the most common causes of FTT, and then follow by GI (13.4%), allergic and infectious disorders in decreasing order. The data showed that average caloric intake in patients with FTT was 76,2% of recommended amount. FTT patients with CGD, IUGR, and idiosyncrasy had tendency to take small foods. The FTT children with prematurity, IUGR and pathologic FTT, were short and thin for their ages. However FTT children with CGD and FSS had tendency to be thin with relatively normal heights for their ages, in comparison with those of the children with prematurity, IUGR and pathologic FTT. Conclusion: The diagnosis of FTT was easily obtained with simple and through medical history, physical examination, and minimal laboratory tests. In this study, organic FTT was more prevalent than physiologic one. This results indicate that early intervention is mandatory, because children may develop significant long-term sequelae from nutritional deficiency.

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Effect of Raw Broun Rice and Job식s Tear Supplemented Diet on Serum and Hepatic Lipid Concentrations, Antioxidative System, and Immune Function of Rats (현미 및 율무 함유 생식이 영양불균형이 유도된 흰쥐의 체내 지질농도, 항산화체계 및 면역기능에 미치는 영향)

  • 박진영;양미자;전혜승;이진희;배희경;박태선
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.2
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    • pp.197-206
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    • 2003
  • Physiological functions of raw grain diet composed of brown rice and Job's Tear (1 : 1) were evaluated in rats raised with nutritionally unbalanced diet including 1% cholesterol, high proportion of animal lipids (lard: soybean oil : 8 : 2), sub-optimal levels of vitamin and mineral mixture along with 0.5% ethanol in drinking water for 4 weeks. Control rats were fed the AIN-93G diet for 9 weeks, and nutritionally unbalanced rats were divided into 3 groups, and fed one of the following diets with 0.5% ethanol in drinking water for another 5 weeks: unbalanced control diet (UCD), raw grain diet (RGD) (UCD +20% brown rice and Job's Tear mixture, and cooked grain diet (CGD)(autoclaved RGD at 121$^{\circ}C$ for 3 hours). Feeding UCD for 5 weeks significantly lowered the food efficiency ratio (FER) of rats than the value for control animals, and dietary supplementation of brown rice and Job's Tear mixture to UCD significantly restored the FER. Serum total cholesterol concentration was significantly lowered in rats fed RGD (24% decrease) or CGD (16% decrease) compared to the value for rats fed UCD. Feeding RGD for 5 weeks significaly lowered the serum LDL+VLDL-cholesterol concentration (26% decrease), as well as the hepatic cholesterol level (16% decrease) than the values for UCD rats. Animals fed CGD (38% decrease) or RGU (59% decrease) showed significantly lower level of hepatic thiobarbituric acid reactive substances (TBARS) compared to the value for rats fed UCD (p<0.05), although hepatic activities of antioxidative enzymes were not influenced by dietary supplementation. Feeding RGD for 5 weeks significantly increased CD4$^{+}$ T-cell population along with CD4$^{+}$/CD8$^{+}$ ratio of mesenteric lymph nodes compared to those for UCD rats (p<0.05). In conclusion, dietary supplementation of brown rice and Job's Tear mixture as raw grains exhibited superior activity lowering blood and hepatic levels of cholesterol, and improving mesenteric lymph nodes immune function of rats to the cooked grain mixture of identical ingredients.

Design Guidlines of Geothermal Heat Pump System Using Standing Column Well (수주지열정(SCW)을 이용한 천부지열 냉난방시스템 설계지침)

  • Hahn, Jeong-Sang;Han, Hyuk-Sang;Hahn, Chan;Kim, Hyong-Soo;Jeon, Jae-Soo
    • Economic and Environmental Geology
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    • v.39 no.5 s.180
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    • pp.607-613
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    • 2006
  • For the reasonable use of low grade-shallow geothermal energy by Standing Column Well(SCW) system, the basic requirements are depth-wise increase of earth temperature like $2^{\circ}C$ per every 100m depth, sufficient amount of groundwater production being about 10 to 30% of the design flow rate of GSHP with good water quality and moderate temperature, and non-collapsing of borehole wall during reinjection of circulating water into the SCW. A closed loop type-vertical ground heat exchanger(GHEX) with $100{\sim}150m$ deep can supply geothermal energy of 2 to 3 RT but a SCW with $400{\sim}500m$ deep can provide $30{\sim}40RT$ being equivalent to 10 to 15 numbers of GHEX as well requires smaller space. Being considered as an alternative of vertical GHEX, many numbers of SCW have been widely constructed in whole country without any account for site specific hydrogeologic and geothermal characteristics. When those are designed and constructed under the base of insufficient knowledges of hydrgeothermal properties of the relevant specific site as our current situations, a bad reputation will be created and it will hamper a rational utilization of geothermal energy using SCW in the near future. This paper is prepared for providing a guideline of SCW design comportable to our hydrogeothermal system.

CysQ of $Cryptosporidium$ $parvum$, a Protozoa, May Have Been Acquired from Bacteria by Horizontal Gene Transfer

  • Lee, Ji-Young;Kim, Sang-Soo
    • Genomics & Informatics
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    • v.10 no.1
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    • pp.9-15
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    • 2012
  • Horizontal gene transfer (HGT) is the movement of genetic material between kingdoms and is considered to play a positive role in adaptation. $Cryptosporidium$ $parvum$ is a parasitic protozoan that causes an infectious disease. Its genome sequencing reported 14 bacteria-like proteins in the nuclear genome. Among them, cgd2_1810, which has been annotated as CysQ, a sulfite synthesis pathway protein, is listed as one of the candidates of genes horizontally transferred from bacterial origin. In this report, we examined this issue using phylogenetic analysis. Our BLAST search showed that $C.$ $parvum$ CysQ protein had the highest similarity with that of proteobacteria. Analysis with NCBI's Conserved Domain Tree showed phylogenetic incongruence, in that $C.$ $parvum$ CysQ protein was located within a branch of proteobacteria in the cd01638 domain, a bacterial member of the inositol monophosphatase family. According to Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, the sulfate assimilation pathway, where CysQ plays an important role, is well conserved in most eukaryotes as well as prokaryotes. However, the Apicomplexa, including $C.$ $parvum$, largely lack orthologous genes of the pathway, suggesting its loss in those protozoan lineages. Therefore, we conclude that $C.$ $parvum$ regained cysQ from proteobacteria by HGT, although its functional role is elusive.