• Title/Summary/Keyword: CD34+

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Highly efficient blue phosphorescent organic light-emitting device using new host materials

  • Seo, Yu-Seok;Kim, Tae-Yong;Moon, Dae-Gyu
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.817-819
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    • 2009
  • We have developed highly efficient blue phosphorescent organic light-emitting devices (PHOLEDs) with simplified architectures using new host materials. The Blue PHOLED with new host:FIrpic emitting layer exhibits a maximum luminance efficiency of 34 cd/A and a low operating voltage 5 V at a high luminance of 1212 cd/$m^2$.

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Substituent Effects on Conformational Changes in (+)-CSA Doped Polyaniline Derivatives

  • Lee, Eung;Kim, Eunok
    • Bulletin of the Korean Chemical Society
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    • v.34 no.7
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    • pp.2111-2116
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    • 2013
  • This paper reports substituent effects on the conformational changes in polyaniline (PAni) derivatives. PAni, poly-o-toluidine (POT), and poly-o-anisidine (POA) were formed by potentiodynamic electropolymerization in aqueous solution containing (+)-camphorsulfonic acid (CSA) as a dopant. UV-Vis spectroscopy and cyclic voltammetry measurements revealed that the methyl group showed a greater steric hindrance than the methoxy group. Further, the doping level decreased with increasing steric hindrance. The sign pattern of the circular dichroism (CD) bands for POA was opposite to that for PAni. However, no CD bands were observed in POT. The steric hindrance caused helical inversion, but at a high level of steric hindrance, the helical conformation could not be adopted, because of the reduced doping level. The reduced crystallinity was greatly affected by the decreased doping level. The steric effect influenced the polymer conformation and the doping level, thus determining the optical activity, morphology, and crystallinity of the PAni derivatives.

Synthesis, Crystal Structures and Properties of Two 3D CdII and ZnII Complexes with a 3-Fold Interpenetrating Feature

  • Lin, Hongyan;Sui, Fangfang;Liu, Peng;Wang, Xiuli;Liu, Guocheng
    • Bulletin of the Korean Chemical Society
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    • v.34 no.7
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    • pp.2138-2142
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    • 2013
  • Two new 3D coordination complexes [Cd(3-bpcd)(pht)] (1) and [Zn(3-bpcd)(pht)] (2) [3-bpcd = N,N'-bis(pyridin-3-yl)cyclohexane-1,4-dicarboxamide, $H_2pht$ = phthalic acid] have been hydrothermally synthesized. X-ray diffraction analysis reveals that the complexes 1 and 2 represent a 4-connected diamondoid topology with a 3-fold interpenetrating feature. Moreover, the fluorescent properties of complexes 1 and 2 are studied.

Intracranial Solitary Fibrous Tumor

  • Jang, Jun-Won;Kim, Chang-Hyun;Yoo, Chong-Woo;Moon, Jae-Gon
    • Journal of Korean Neurosurgical Society
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    • v.39 no.1
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    • pp.64-67
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    • 2006
  • Solitary fibrous tumor is a spindle cell neoplasm that can arise in any place of the body. Intracranial solitary fibrous tumors are rare. To our knowledge, only 57 cases with intracranial lesion have been reported. In Korea three cases have been reported. Our case was a 23-year-old woman who presented with morning headache. MRI showed a large intra-axial mass involving falx with typically isointense and heterogeneous strong enhancement on T1 weighted image in the right parieto-occipital region. Histologically the tumor showed spindle shaped cells within matrix with thick collagen deposition, hypercellularity, focal necrosis, and pleomorphism. Immunohistochemical study demonstrated diffuse positivity for CD34, Vimentin, Reticulin. In case of the intracranial tumors involving the meninges, we also should consider the solitary fibrous tumor with immunohistochemical staining for accurate diagnosis.

Meningeal Solitary Fibrous Tumor

  • Lee, Jong-Myong
    • Journal of Korean Neurosurgical Society
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    • v.37 no.3
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    • pp.232-234
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    • 2005
  • We report a rare case of a patient with meningeal solitary fibrous tumor. A 60-year-old woman presented with right leg monoparesis. Brain magnetic resonance imaging demonstrates a well enhancing huge mass, located in left parietal lobe. Cerebral angiography demonstrating increased vascularity in area of the tumor, which had feeder vessels extending from the internal carotid artery and external carotid artery. A presumptive diagnosis of meningioma or hemangiopericytoma was considered. At surgery, the consistency was firm and had destroyed the dura and skull. A gross total resection was performed. Immunohistochemically, tumor was strongly, and widely, positive for CD34 and vimentin. There was no staining for epithelial membrane antigen(EMA), S-100 protein, cytokeratin, and glial fibrillary acidic protein (GFAP). Differential diagnosis of intracranial solitary fibrous tumor includes fibroblastic meningioma, meningeal hemangiopericytoma, neurofibroma, and schwannoma.

Solitary Fibrous Tumor of the Meninges - A Case Report - (수막의 고립성 섬유성 종양 - 1예 보고 -)

  • Kong, Tae Shik;Son, Hyun Jin;Choi, Ha Young;Moon, Woo Sung;Chung, Myoung Ja
    • Journal of Korean Neurosurgical Society
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    • v.30 no.12
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    • pp.1439-1442
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    • 2001
  • Solitary fibrous tumor(SFT) is a spindle cell neoplasm that usually arises in the pleura. Its involvement of the meninges is rare but increasingly being reported. Our case was a 33-year-old man who presented with clonic seizure around the right mouth angle and sensory disturbance at the right hand. Radiological studies showed a large extra-axial, dural-based mass in the left fronto-parietal region, typically isointense with gray matter and heterogeneous strong enhancement on T1-weighted images. Histologically, the tumor was composed of spindle-shaped cells growing in fascicles within the collagenous matrix. Immunohistochemical staining demonstrated diffuse CD34 positivity. Awareness of this neoplasm is necessary to accurate diagnosis.

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Effect of Deer Blood on Aplastic Anemia Induced Mouse (녹혈이 빈혈유발 Mouse에 미치는 영향)

  • Kim, Sang-Mi;Ha, Hye-Kyung;Hong, Soon-Bok;Kim, Chung-Sook
    • Korean Journal of Oriental Medicine
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    • v.10 no.1
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    • pp.127-135
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    • 2004
  • Hematopoietic stem cells in bone marrow form all kinds of blood cells. In traditional medicine, functions of bone marrow cells are very similar to those of Essence(精) which is a fundamental factor of physical development and reproduction. Our experiment examined the effect of deer blood on aplastic anemia induced mouse using cyclophosphamide 150 mg/kg i.p injection before experiment and then another cyclophosphamide 120 mg/kg i.p injection on day 10. Then we administrated dried deer blood in distilled water for 5 days, 9 days and 10 days. We examined blood and marrow samples. In results, deer blood showed a trend of effectiveness on recovery of red blood cells and erythropoietin although they were not statistical significant. And deer blood did not show changes in CD34.

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Phosphorescent Iridium Complexes for OLEDs Based on 1-Phenylpyrazole Ligands with Fluorine and Methyl Moieties

  • Yoon, Seung Soo;Song, Ji Young;Na, Eun Jae;Lee, Kum Hee;Kim, Seong Kyu;Lim, Dong Whan;Lee, Seok Jae;Kim, Young Kwan
    • Bulletin of the Korean Chemical Society
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    • v.34 no.5
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    • pp.1366-1370
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    • 2013
  • A series of phosphorescent iridium(III) complexes 1-4 based on phenylpyrazole were synthesized and their photophysical properties were investigated. To evaluate their electroluminescent properties, OLED devices with the structure of ITO/NPB/mCP: 8% Iridium complexes (1-4)/TPBi/Liq/Al were fabricated. Among those, the device with 3 showed the most efficient white emission with maximum luminance of 100.6 $cd/m^2$ at 15 V, maximum luminous efficiency of 1.52 cd/A, power efficiency of 0.71 lm/W, external quantum efficiency of 0.59%, and CIE coordinates of (0.35, 0.40) at 15.0 V, respectively.

Association of the Porcine Cluster of Differentiation 4 Gene with T Lymphocyte Subpopulations and Its Expression in Immune Tissues

  • Xu, Jingen;Liu, Yang;Fu, Weixuan;Wang, Jiying;Wang, Wenwen;Wang, Haifei;Liu, Jianfeng;Ding, Xiangdong;Zhang, Qin
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.4
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    • pp.463-469
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    • 2013
  • Cluster of differentiation 4 (CD4) is mainly expressed on $CD4^+$ T cells, which plays an important role in immune response. The aim of this study was to detect the association between polymorphisms of the CD4 gene and T lymphocyte subpopulations in pigs, and to investigate the effects of genetic variation on the CD4 gene expression level in immune tissues. Five missense mutations in the CD4 gene were identified using DNA pooling sequencing assays, and two main haplotypes (CCTCC and AGCTG) in strong linkage disequilibrium (with frequencies of 50.26% and 46.34%, respectively) were detected in the population of Large White pigs. Our results indicated that the five SNPs and the two haplotypes were significantly associated with the proportions of $CD4^-CD8^-$, $CD4^+CD8^+$, $CD4^+CD8^-$, $CD4^+$ and $CD4^+/CD8^+$ in peripheral blood (p<0.05). Gene expression analysis showed the mRNA level of the CD4 gene in thymus was significantly higher than that in lymph node and spleen (p<0.05). However, no significant difference was observed between animals with CCTCC/CCTCC genotype and animals with AGCTG/AGCTG genotype in the three immune tissues (p>0.05). These results indicate that the CD4 gene may influence T lymphocyte subpopulations and can be considered as a candidate gene affecting immunity in pigs.