• 제목/요약/키워드: CD18

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LC-MS/MS 및 ICP를 이용한 당뇨환의 화학적 특성 분석 (Characteristic Effects of Dangnyo-hwan for Diabetes Control Studied Using LC-MS/MS and ICP)

  • 인정도;임대식;문승호;김원일
    • 대한한방내과학회지
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    • 제36권3호
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    • pp.217-227
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    • 2015
  • Objectives: The primary aim of this study was to identify bioactive compounds in Dangnyo-hwan, a Korean herbal medicine, through instrumental analysis using LC-MS/MS and ICP, and investigate its potential use in diabetes treatment. Methods: The extract of Dangnyo-hwan has 12 medicinal herbs; these were compared with 18 marker substances selected from literature survey. Results: LC-MS/MS analysis could detect 9 of the 18 bioactive compounds: citruline, catalpol, berberine, ginsenoside Rb1, ginsenoside Rg1, oleanolic acid, β-sitosterol, mangiferin, and schizandrin. While harmful heavy metals such as As, Pb, Cd, Hg, Ni, and Cu were not present in high concentrations, Zn concentration was 4.2 mg in 100 g Dangnyo-hwan. Conclusions: Instrumental analysis such as LC-MS/MS and ICP was successfully used to identify bioactive compounds in Dangnyo-hwan. Detection of 9 bioactive substances and Zn from the herb medicine is a valuable finding, and suggests that Dangnyo-hwan is a candidate medicine for diabetes. Further investigations like in vitro assay, percent GPR 119 activity, and percent human DGAT-1 inhibition are underway.

원통형 ICP 광원 모드변환의 안테나 의존성 (Antenna Dependency of Mode Transition in Cylindrical ICP Light-source)

  • 양종경;백광현;이종찬;박대희;윤양웅
    • 한국전기전자재료학회논문지
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    • 제18권8호
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    • pp.772-778
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    • 2005
  • In this paper, we designed the cylindrical type light source that had a electromagnetic principle of inductively coupled plasma, and measured its electrical-optical properties. Using the principle of transformer, electrically equivalent circuit of cylindrical type light source was analyzed. According to the parameters of electromagnetic induction which were diameter of coil with $0.3\~1.2\;mm{\Phi}$, number of turns with $4\~12$ turns, distance with $40\~120$ mm and RF power with $10\~150$ W, the electrical and optical properties were measured. When diameter of coil was $0.3\;mm{\Phi}$, number of turns was 8 turns and distance was 40 mm, the highest brightness of 29,730 $cd/m^2$ was shown with RF power 150 W. The relationship between electromagnetic induction and plasma discharges was shown by mode transition from E-mode to H-mode.

SI 가솔린 엔진의 과급 및 흡기가 엔진 성능에 미치는 영향에 대한 연구 (A Study About the Effect of Supercharging and Intake Charge on Engine Performance in Spark Ignition Gasoline Engine)

  • 김기복;진석준;김치원;윤창식;한성현
    • 한국산업융합학회 논문집
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    • 제18권2호
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    • pp.110-118
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    • 2015
  • In this study, it is designed and used the test engine bed which is installed with turbocharger, and in addition to equipped using by oxygen adder. It has been controlled the oxygen volumetric fraction of intake air chrge, and supercharged flow rate into the cylinder of SI 4-stroke engine, and then, has been analyzed engine performance, combustion characteristics, and exhaust emission as analysis parameters. The tested parameters were the oxygen fraction and the variation of engine speed and air-fuel ratio.

하수슬러지의 Biochar특성을 이용한 토양내 중금속 제거 연구 (A Study on the Removal of Heavy Metals in Soil by Sewage Sludge Biochar)

  • 김혜원;배선영;이재영
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제18권3호
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    • pp.58-64
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    • 2013
  • This study proposed a low temperature hydrothermal carbonization to treat and recycle sewage sludge and determined the optimal conditions for the biochar production. The physical and chemical properties of biochar were analyzed and its sorption capacity for heavy metals was evaluated. To produce biochar, 50 g of sewage sludge was heated at 220, 230, and $240^{\circ}C$ for 1, 2, 3, 5, 8, and 10 hours in a reactor. The optimal conditions to produce biochar was $230^{\circ}C$ and 8 hours. Sorption capacity tests were conducted for arsenic (As), cadmium (Cd), copper (Cu), lead (Pb), zinc (Zn) and nickel (Ni). Among them, lead was shown the highest heavy metal adsorption efficiency of biochar, followed by copper, cadmium, zinc, and nickel, but arsenic was hardly adsorbed overall.

서울한강 둔치 및 안양천 하류부 둔치주변 토양오염 조사연구 (Estimated Toxic Metal Concentrations in Riverbank Soil of the Han and Anyang Rivers)

  • 김설아;이재영;오병택
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제18권7호
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    • pp.12-17
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    • 2013
  • Heavy metal contamination of soil and water from industrial sources remains a worldwide environmental concern. Concentrations of toxic metals were measured in soil from banks of the Han and Anyang rivers. Pre-monsoon samples contained the highest heavy metal concentrations (Cu > As > Pb > Cd > $Cr^{6+}$; up to 57.80, 38.23, 25.43, 2.21, 0.32 mg/kg, respectively), but concentrations decreased at all sites during the monsoon and post-monsoon seasons. Higher heavy metal concentrations in pre-monsoon samples may be attributed to dust pollution, especially from roads near the river. A gradual reduction in heavy metal concentrations during the rainy season may be due to washing out. The high concentration of metals could cause health problems, especially in residential areas.

수질 모니터링을 위한 암모니아 분석 칩과 중금속 센서

  • 박준식;황길호;강성군
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2011년도 춘계학술발표대회
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    • pp.18.2-18.2
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    • 2011
  • 생활수준이 향상되고, 환경오염이 가속되면서 환경에 대한 관심이 더욱 증대되고 있다. 수질센서의 경우, 그 측정 항목이 매우 다양하고, 높은 정밀도를 요하고 있을 뿐만 아니라 지속적인 실시간 모니터링을 요구하고 있어, 기술적으로 해결해야 할 문제가 많이 남아 있다. 또한, 현재 약 15% 정도로 매우 낮은 국산화율을 보이고 있어, 대부분의 주요 센서들이 수입에 의존하고 있는 실정이다. 수질을 측정하기 위한 센서는 크게 두 가지 형태로 나누어 질 수 있는데, 하나는 flow injection analysis (FIA) 방식이며, 다른 하나는 Probe 방식의 센서이다. 본 발표에서는 수질 센서에 대한 최근 국내 기술 동향과, 수질 모니터링을 위한 Lab-on-a-chip 형 암모니아 분석 칩, Probe 형 중금속 센서 연구 개발 결과를 요약하고자 한다. 암모니아 분석 칩은 마이크로 유체 소자 내에서 Berthelot reaction을 유도하고, 흡광법에 의하여 물 속에 존재하는 암모니아를 간접적으로 측정하는 방법이다. 또한, 중금속 센서로 일반적인 working electrode 소재로 사용되는 독성이 있는 Hg 보다 친환경적인 개발된 bismuth-modified carbon nanotube와 같은 Bi계 복합소재를 적용하여 물 속에 존재하는 저 농도의 Pb, Cd, Zn을 측정 분석할 수 있었다. 본 연구를 통해 개발된 분석칩과 중금속 센서를 이용하여 하천에서 샘플링된 물에서의 암모니아 및 중금속 농도를 각각 분석할 수 있었다.

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Assessment of Heavy Metal (loid) Pollution Using Pollution Index in Agricultural Field Adjacent to Industrial Area

  • Min, Kyungjun;Hong, Youngkyu;Choi, Wonsuk;Kim, Daebok;Kim, Sungchul
    • 한국토양비료학회지
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    • 제49권6호
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    • pp.768-775
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    • 2016
  • Heavy metal pollution in arable field is an critical problem due to crop safety. For this reason, national survey of heavy metal pollution in the arable field near at the industrial area has been conducted from 1999 in Korea. The main purpose of this research was to monitor heavy metal pollution in Chungnam/chungbuk province and to evaluate pollution index (PI) in soil. Total of 15 sampling locations were examined and average concentration of each heavy metals were following: As - $2.99{\pm}2.63$, Cd - $0.23{\pm}0.07$, Cu - $9.35{\pm}6.48$, Ni - $9.26{\pm}8.03$, Pb - $10.18{\pm}3.32$, Zn - $52.9{\pm}17.18$. No sampling site was exceeded threshold level of each heavy metals. Calculated PI in soil was ranged between 0.03 - 0.27 indicating that also no heavy metal pollution is occurred in examined sampling locations. Although, no heavy metal pollution was observed in the examined sites but monitoring of heavy metal pollution should be continued for possible accidental pollution in arable field near at the industrial area.

Preparation and Characterization of White Phosphorescence Polymer Light Emitting Diodes Using PFO:Ir(ppy)3:MDMO-PPV Emission Layer

  • Park, Byung-Min;Chang, Ho-Jung
    • 마이크로전자및패키징학회지
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    • 제18권4호
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    • pp.79-83
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    • 2011
  • White phosphorescence polymer light emitting diodes (WPhPLEDs) with a glass/ITO/PEDOT:PSS/PFO:$Ir(ppy)_3$:MDMO-PPV/TPBI/LiF/Al structure were fabricated to investigate the effects of $Ir(ppy)_3$ doping concentrations on the optical and electrical properties of the devices. PFO, $Ir(ppy)_3$ and MDMO-PPV conjugated polymers as host and guest materials in the emission layer were spin coated at various concentrations of $Ir(ppy)_3$ ranging from 0.0 to 20.0 vol.%. As the concentration of $Ir(ppy)_3$ increased from 5.0 to 20.0 vol.%, the luminance and current efficiency values of the devices decreased clearly, which are attributable to the quenching effect at a high doping concentration. The maximum luminance and current density were 2850 $cd/m^2$ and 741 $mA/cm^2$, respectively for a WPhPLED with an $Ir(ppy)_3$ concentration of 5.0 vol.%. The CIE color coordinates were about x=0.33 and y=0.34 at 11V, showing a good white color.

노면배수에 함유된 미량오염물질 및 제거에 관한 연구 (A Study on the Micropollutants and Removal of Micropollutants Contained in Road Runoff)

  • 김부길;박흥재;장성호
    • 한국환경과학회지
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    • 제18권2호
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    • pp.215-219
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    • 2009
  • Micropollutants, which can be caused by imperfect combustion, are toxic chemical compound that flows into the river system after being contained in road runoff, a non-point source pollutant and accumulates in the body. The micropollutants that have characteristics such as toxicity, persistence, bio-accumulation, long-range transportation behave so similarly to micro particles that they can be removed by means of filtration or absorption. This study has examined the kinds and concentrations of micropollutants contained in deposited road particles. It has revealed that the kinds of micropollutants contained in the clarified supernatant liquid of deposited road particles are heavy metals and polycyclic aromatic hydrocarbons(PAHs) composed of two or three benzene rings, including naphthalene and acenaphthalene. Their concentrations have been shown to be low, with 0.418 mg/L, 0.058 mg/L, 0.104 mg/L, 0.014 mg/L, 0.00075 mg/L for Zn, Pb, Cu, Cr, Cd, respectively and 0.00156 mg/L and 0.00184 mg/L for naphthalene and acenaphthalene.

회전안정탄약의 비행운동 모사장치에 대한 실험적·수치해석적 연구 (Experimental and Numerical Studies on a Test Equipment for the Replication of Flight Motions of Spin-Stabilized Ammunition)

  • 이영기;박성택;송이화;최민수
    • 한국군사과학기술학회지
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    • 제18권6호
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    • pp.728-735
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    • 2015
  • A gas gun system to replicate the flight motions of large caliber spin-stabilized ammunition has been investigated experimentally and numerically. The system is specially designed to study aerodynamic characteristics and dynamics of a flight body ejected from a cargo shell or a subsonic projectile itself at up to 2,000 rpm and 100 m/s. Raynolds-averaged Navier-Stokes equations with a overset mesh technique and 6-DOF dynamics were solved to decide the chamber pressure according to the muzzle velocity input by users. The predicted velocity values show less than 6 % of discrepancies compared to experimental data. The system has successfully been tested for the simulation of deployment of a parafoil for a 155 mm gun-launched projectile.