• The Journal of the Korea Contents Association
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• v.17 no.1
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• pp.201-212
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• 2017

This study presented the new evaluation index which can evaluate the discrimination of DEA models. To evaluate the discrimination of DEA models, data were analyzed using importance index as suggested in previous study and the coefficient of variation as suggested in this study for the discrimination evaluation. This study selected the CCR-DEA, BCC-DEA, entropy, bootstrap, super efficiency, and cross efficiency DEA model for the discrimination evaluation and accomplished empirical analysis. In order to grasp the rank correlation of the models, this study implemented the rank correlation analysis between the efficiency of CCR model and BCC model and entropy, bootstrap, super efficiency, and efficiency of the cross efficiency model. The obtained results of this study are as follows. First, the discrimination rank of models using the importance index and the coefficient of variation was shown to be identical. Therefore, the coefficient of variation can be used the discrimination evaluation index of DEA model. Second, the discrimination of the super efficiency model was found to be the highest rank among 4 models according to the analysis of this present study. Third, the highest rank correlation with CCR model was the super efficiency model. In addition, the super efficiency model was found to be the highest rank correlation with BCC model.

• The Journal of Fisheries Business Administration
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• v.46 no.2
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• pp.111-125
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• 2015

This study is to analyze the efficiency of Korean sea food manufacturing using Data Envelopment Analysis. Firstly, based on an output oriented traditional CCR, BCC model, the study estimated the efficiency scores. The average estimates of technical, pure technical, and scale efficiency turned out 0.6517, 0.7184, 0.9074 respectively, which are separated for 50 marine corporations. The 10 DMUs were efficient under CCR model while the 17 DMUs under BCC model. Also, the study suggested that the operating profit of the two output factors should be more increased relatively and averagely from the viewpoint of efficiency improvement. Secondly, super efficiency scores are estimated under super efficiency and SBM model. As a result, it came to be possible to distinguish and rank the efficiency of the efficient DMUs. The highest score was 4.2975 under Super-CCR, was 2.4947 under Super-BCC, was 2.7160 under SBM-Super-CCR, and was 1.5319 under SBM-Super-BCC model. The average estimates of super efficiency were 0.76 and 0.82 under Super-CCR and Super-BCC model respectively, and were 0.61 and 0.67 under SBM-Super-CCR and SBM-Super-BCC model. Finally, the study conducted a rank-sum test, Wilcoxon-Mann-Whitney test, to find a statistical significance of heterogeneity existing in efficiencies among the sample corporations. The result showed that there was a significant difference in average efficiency between Dried, Salted product manufacturing and Frozen product manufacturing under BCC-Super efficiency model at 10% level of significance. Furthermore, TOBIT model was applied to find out the potential factors that might influence the efficiency, Wilcoxonand the results showed debt and sales cost influenced all of the technical, pure technical, and scale efficiency, while net profit influenced only the technical efficiency.

• Journal of Navigation and Port Research
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• v.34 no.7
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• pp.577-585
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• 2010

This paper analyzes the efficiency of Korean Ship Component Part Manufacturer firms using DEA model. We evaluated the CCR, BCC efficiency and RTS of 30 Korea Ship Component Part Manufacturer firms. We also suggested the Korean Ship Component Part Manufacturer firms that can be benchmarked based on analyzed information. The result showed five enterprises whose values of CCR efficiency are 1, and eleven enterprises whose values of BCC efficiency are 1. RTS indicated IRS of 1 firms, DRS of 24 firms and CRS of 5 firms.

• Journal of Integrative Natural Science
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• v.7 no.4
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• pp.234-240
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• 2014

C-C chemokine receptor type 4 (CCR4) is a chemokine receptor with seven transmembrane helices and it belongs to the GPCR family. It plays an important role in asthma, lung disease, atopic dermatitis, allergic bronchopulmonary aspergillosis, cancer, inflammatory bowel disease, the mosquito-borne tropical diseases, such as dengue fever and allergic rhinitis. Because of its role in wide spectrum of disease processes, CCR4 is considered to be an important drug target. Three dimensional structure of the protein is essential to determine the functions. In the present study homology modeling of human CCR4 was performed based on crystal structure of CCR5 chemokine receptor. The generated models were validated using various parameters. Among the generated homology models the best one is selected based on validation result. The model can be used for performing further docking studies to identifying the critical interacting residues.

• Journal of Korea Port Economic Association
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• v.33 no.4
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• pp.135-148
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• 2017

This study fist raises the following research question. How does the port congestion affect port operational efficiency? To answer the question, this study adopts slacks based measure data envelopment analysis (SBM-DEA) model to analyze the efficiency of port considering the congestion. As a result of the DEA-CCR(Chanres, Cooper and Rhodes) model, both Busan(2011) and Ulsan(2011) are the most efficient decision making units(DMUs). As a result of the DEA-BCC(Banker, Chanrnes, and Cooper) model, Busan(2011), Ulsan(2011), Ulsan(2012), Busan(2012), and Yeosu Gwangyang(2012) are the most efficient DMUs. As a result of SBM-DEA model, Ulsan(2012), Busan(2011), Busan(2012), Incheon(2011), and Ulsan(2011) are the most efficient DMUs considering the port congestion. The result of DEA-CCR BCC model is not identical with the result of SBM-DEA model analysis. It means the port congestion does less affect the port operational efficiency. Should the number of the vessels with the port congestion minimize, Incheon and Yeosu Gwangyang port could save lots of the port congestion cost for a total of three years.

• The Journal of the Korea Contents Association
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• v.12 no.7
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• pp.284-294
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• 2012

In the study, we estimate efficiencies using CCR model of DEA, Super efficiency(AP) model, and super-SBM model with the data of 32 regional public hospitals in Korea from 205 to 2009. With Wilcoxon-Mann-Whitney statistics, we analyze efficiency differences for environmental factors(regions, type of hospital, type of operations, type of education training, relative importance of madicaids) among regional public hospitals. The results can be summarized as follows. Firstly, technical inefficiencies of regional public hospitals range from 15% to 17% in CCR model, 13% to 15% in AP model, 7% to 12.6% in SuperSBM model. Second, we confirm that environmental factors of hospitals cause different inefficiencies among them. The implication of this study is that policy and institutional change may need to improve the efficiencies along with internal managerial reform.

• Journal of Integrative Natural Science
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• v.6 no.3
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• pp.163-169
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• 2013

The chemokine receptor CCR1 a GPCR super family protein contains seven transmembrane domains. It plays an important role in rheumatoid arthritis, organ transplant rejection, Alzheimer's disease and also causes inflammation. Because of its role in disease processes, antagonism of CCR1 became an attractive therapeutic target. In the current study, we have taken a novel series of recently reported CCR1 antagonist of 1-(4-Phenylpiperazin-1-yl_-2-(1H-Pyrazol-1-yl) ethanone derivatives and performed a HQSAR analysis. The model was developed with Atom (A) and bond (B) parameters and with different set of atom counts to improve the model. The results of HQSAR showed good predictive ability in terms of $r^2$ (0.904) and $q^2$ (0.590) with 0.710 as standard error of prediction and 0.344 as standard error of estimate. The contribution map depicted the atom contribution in inhibitory effect. Compound-14 which was reported to be a highly active compound showed positive atom contribution in three R groups ($R^3$. $R^{5a}$ and $R^{2b}$) in inhibitory effect, which could be the reason why this compound is highly active compound whereas, the lowest active compound-6 showed negative contribution to inhibitory effect.

• The Journal of the Korea Contents Association
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• v.13 no.1
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• pp.366-375
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• 2013

Recently, management of Newspaper developmet of the internet news, broadcasting and free newspapers escalated competition between newspaper companies and other media companies as well as competition among newapaper companies. This paper analyzes the efficiency of Korean Newapaper using DEA model. We evaluate the CCR-O, BCC-O efficiency, SE and RTS of 30 Newspaper. We also suggest the Newpaper which can be benchmarked based on analyzed information. The result shows that ten Nespaper whose values of CCR-O efficiency are 1, and Fourteen Nespaper whose values of BCC efficiency are 1. RTS indicates IRS of 1 firms, DRS of 16 firms and CRS of 13 firms. To variables on the effectiveness of newspaper publishing companies for the understanding and performance analysis.

• Journal of Korean Society for Quality Management
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• v.35 no.3
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• pp.21-36
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• 2007

This article is to analyze the service efficiency of public sector using Data Envelopment Analysis(DEA). We tried to measure the public service quality and overall satisfaction by using several DEA models, degree of combination and top2box which is a little bit different methodology from traditional ones. We used CCR, Super-efficiency and Slack based measure(SBM) model in DEA to measure public service efficiency of the 16 public institutions(7 City Halls and 9 Provincial offices). Since the traditional method based on the measurement model(CCR, BCC) has the fundamental problems without taking account of the existence of slacks inputs and outputs in several efficient units, we suggest to measure the exact amount of efficiency and inefficiency of the public sector and rank analysis many efficient units exactly through the slacks-based measure model(SBM)

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3429-3443
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• 2013

Chemokine receptor (CCR2) is a G protein-coupled receptor that contains seven transmembrane helices. Recent pharmaceutical research has focused on the antagonism of CCR2 and candidate drugs are currently undergoing clinical studies for the treatment of diseases like arthritis, multiple sclerosis, and type 2 diabetes. In this study, we analyzed the time dependent behavior of CCR2 docked with a potent 4-azetidinyl-1-aryl-cyclohexane (4AAC) derivative using molecular dynamics simulations (MDS) for 20 nanoseconds (ns). Homology modeling of CCR2 was performed and the 4AAC derivative was docked into this binding site. The docked model of selected conformations was then utilized to study the dynamic behavior of the 4AAC enzyme complexes inside lipid membrane. MDS of CCR2-16b of 4AAC complexes allowed us to refine the system since binding of an inhibitor to a receptor is a dynamic process and identify stable structures and better binding modes. Structure activity relationships (SAR) for 4AAC derivatives were investigated and reasons for the activities were determined. Probable binding pose for some CCR2 antagonists were determined from the perspectives of binding site. Initial modeling showed that Tyr49, Trp98, Ser101, Glu291, and additional residues are crucial for 4AAC binding, but MDS analysis showed that Ser101 may not be vital. 4AAC moved away from Ser101 and the hydrogen bonding between 4AAC and Ser101 vanished. The results of this study provide useful information regarding the structure-based drug design of CCR2 antagonists and additionally suggest key residues for further study by mutagenesis.