• 제목/요약/키워드: CCI$_4$

검색결과 140건 처리시간 0.022초

수컷 SD(rat)에 $CCI_4$ 처리후 지구자 추출액의 간 보호효과 연구 (Effect of Hovenia dulcis on liver protection in SD male rats treated with $CCl_4$)

  • 김상웅;마진열
    • 한국한의학연구원논문집
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    • 제12권1호
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    • pp.103-109
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    • 2006
  • We investigated liver protection effect of the Hovenia dulcis Thunb extraction which has treated with carbon tetrachloride ($CCl_4$, 1.0 ML/kg) in SD male rat (20 weeks). We observed the amount of leukocyte, erythrocyte, hemoblobin and hematocrit are increased and the number of plaque is decreased for treatment of $CCl_4$, However, after treatment of Hovenia dulcis Thunb extraction (15 mL/kg), we have same result that of control group which has treated with $CCl_4$ The blood biological data showed that the value of AST (Aspartate aminotransferase), ALT(Alanine aminotransferase) and LDH (Lactate dehydronase) are increased significantly for the negative control group compared to that of control group. For experimental group, respectively, In addition, it was confirmed that the recovery effect of a mysterious death of an interstitial cell of the experimental group is to be compared to that of the negative control group for a sample of pathological tissue.

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장애인 건강주치의 시범사업 수요자의 등록 및 이용수준 영향 요인 분석 (Factors Affecting the Registration and Access Levels of the Pilot Project for the General Physician System among People with Disabilities)

  • 최은희;구여정;임승지
    • 보건행정학회지
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    • 제34권2호
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    • pp.185-195
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    • 2024
  • 연구배경: 장애인의 일상적 건강관리 미흡과 낮은 의료접근성으로 인해 다양한 건강문제 발생 및 과다한 의료비 지출 부담이 발생하고 있다. 이에 "장애인건강권법"에 근거하여 2018년 장애인 건강주치의제도 시범사업을 시행하였으나 2021년 기준 전체 중증장애인 중 시범사업 참여자는 0.2%에 불과하다. 이에 본 연구는 수요자의 장애인 건강주치의 참여 활성화를 위한 시사점을 얻고자, 시범사업 등록 여부와 시범사업 이용수준의 영향요인을 규명하고자 하였다. 방법: 2018년 5월 30일부터 2021년 12월 31일까지 시범사업 정보와 국민건강보험 데이터를 연계하여 이분형 로지스틱 회귀분석과 위계적 다중회귀분석을 통해, 장애인건강주치의 참여 장애인의 시범사업 등록 및 서비스 이용횟수에 영향을 미치는 요인을 분석하였다. 독립변수는 장애유형, 인구사회경제학적 특성과 건강상태(만성질환의 개수, 찰슨동반상병지수(Charlson comorbidity index [CCI]), 외래민감질환 및 복약불순응과 다제약제관리 필요의 해당 여부), 시범사업 서비스 이용 관련 변수를 포함하였다. 결과: 시범사업의 등록 여부에 영향을 주는 요인 분석결과, 주장애관리 가입 대상에 해당하는 장애유형(지체, 뇌병변, 시각, 지적, 정신, 자폐성 장애인)이 그 외 장애유형(odds ratio [OR], 4.157)보다, 군 지역 거주자보다 특별광역시 거주자(OR, 4.330)와 시 지역 거주자(OR, 3.332)가 시범사업에 등록할 확률이 높았으며, CCI와 만성질환 개수와 같은 건강수준의 영향도 있었다. 그러나 주치의 서비스 이용수준의 결정요인으로 참여자의 인구사회학적 특성(장애유형, 연령, 의료보장 형태, 거주지역)과 건강수준(만성질환 개수, CCI) 등 개인적 요인보다 시범사업 서비스 가입 형태에 해당하는 변수군(수요자가 등록한 주치의의 소속 및 서비스 유형)이 더 높은 설명력(20.4%)을 보였다. 결론: 수요자의 장애유형과 지역과 건강수준에 따른 시범사업의 참여 편차를 고려하여 향후 서비스 개발이 필요하며, 수요자의 서비스 이용수준에 공급자의 요양기관 형태나 서비스 유형의 영향력이 큰 바 향후 공급자의 참여 양상과 수요자의 참여수준과의 관계를 분석하는 연구가 필요할 것이다.

Bacillus thuringiensis subsp. indlana(TH109)가 생산한 $\delta$-endotoxin에 관한 연구 (Study on the $\delta$-endotoxin by Bacillus thuringiensis subsp. indiana(TH109))

  • 이광배;채용곤
    • 환경위생공학
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    • 제9권1호
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    • pp.89-96
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    • 1994
  • This report was investigate the biological characteristic of $\delta$-endotoxin of product by TH109 strain, one strain TH109 which has toxicity on Cockroach is isolate and identification. Generally the $\delta$-endotoxin of product by 3. thuringiensis strain was easily soluble in acid, alkaline and organic solvents but $\delta$-endotoxin of product by TH109 strain are insoluble in HCI, NaOH Thiol- reagent(25mM Dithiotheritol, 25mM Dithioeryritol, 25mM Nathioglycolate, 0.2M ESCN, 2% v/v $\beta$-mecaptethanol), organic solvents( acetone, $CCI_{4}$, ether, dioxin MeOH chloroforrh xylene ), Protease. Through this study of $\delta$-endotoxin produced by TH109 strain is insoluble in acid, alkaline, organic solvents and pretense etc. In the point of view, it is greater possibility that $\delta$-endotoxin will be transform into toxin by the reducible materials instead of the reaction of protease in the intestine.

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MC기법과 QA기법을 이용한 직접위성방송채널 성능평가 (Performance Evaluation of Direct Broadcasting Satellite Channel using a MC and QA Method)

  • 정지원;조형래;고성찬
    • 한국정보통신학회논문지
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    • 제3권4호
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    • pp.839-847
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    • 1999
  • 본 논문에서는 MC 시뮬레이션 기법과 QA 시뮬레이션 기법을 이용하여 인접채널간섭, 동위상간섭, 가우시안 잡음이 존재하는 직접위성방송 채널을 성능 평가하였다. 시뮬레이션을 하기 위한 시스템 파라미터들은 현재 무궁화호 위성에서 사용하고 있는 파라미터 및 링크 설계를 기초로 하여 설정하였으며, 두 가지 기법 모두 성능이 수학적 이론 성능에 근접함을 알 수 있었다.

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Evaluation of Hepatoprotective Potential of Cassia tora Leaf Extract

  • Maity, Tapan Kumar;Mandal, Subhash C.;Mukherjee, Pulok K.;Saha, Kakali;Das, J.;Saha, B.P.;Pal, M.
    • Natural Product Sciences
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    • 제3권2호
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    • pp.122-126
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    • 1997
  • Methanolic extract of the leaves of Cassia tom was evaluated for its hepatoprotective potentials in rats by inducing hepatotoxicity with carbon tetrachloride. The extract at a dose of 400 mg/kg orally showed significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.

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부성기체를 용해시킨 불포화 폴리에스터의 Tree 성장과 절연파괴 특성 (The Tree Growth and Breakdown Characteristics of Unsaturated Polyester Dissolving the Electronegative Gases)

  • 이보호;전춘생
    • 대한전기학회논문지
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    • 제41권2호
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    • pp.178-184
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    • 1992
  • This study treats the improvement of the dielectric strength of polymer by eliminating the air in it and dissolving electronegative gases. As experimental material, unsaturated polyester resin was used and the specimen was made by dissolving NS12T. SFS16T abd CCIS12TFS12T gases which have strong electron affinity. And also the electrical properties (tree growth and breakdown characteristics) of them were tested and discussed. The results are as follows. When the specimen dissolved with electronegative gas compared with one with air` 1) The tree breakdown voltage of the former is higher than that of the latter. 2) The tree growth of the former is slower than that of the latter. 3) The temperature dependence of the former is smaller than that of the latter. 4) The breakdown voltage of the specimen dissolved with electronegative gas is much higher than that dissolved with air.

A Multi-Dimensional Radio Resource Scheduling Scheme for MIMO-OFDM Wireless Systems

  • Li, Lei;Niu, Zhisheng
    • Journal of Communications and Networks
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    • 제8권4호
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    • pp.401-409
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    • 2006
  • Orthogonal frequency division multiplexing (OFDM) and multiple input multiple output (MIMO) technologies provide additional dimensions of freedom with spectral and spatial resources for radio resource management. Multi-dimensional radio resource management has recently been identified to exploit the full dimensions of freedom for more flexible and efficient utilization of scarce radio spectrum while provide diverse quality of service (QoS) guarantees. In this work, a multi-dimensional radio resource scheduling scheme is proposed to achieve above goals in hybrid orthogonal frequency division multiple access (OFDMA) and space division multiple access (SDMA) systems. Cochannel interference (CCI) introduced by frequency reuse under SDMA is eliminated by frequency division and time division between highly interfered users. This scheme maximizes system throughput subjected to the minimum data rate guarantee. for heterogeneous users and transmit power constraint. By numerical examples, system throughput and fairness superiority of the our scheduling scheme are verified.

MIND 식단교육을 이용한 치매예방 영양프로그램이 고위험 치매노인의 인지기능 변화에 미치는 영향 (The Effect of Dementia Prevention Nutrition Program Using MIND Diet on the Changes in Cognitive Function of the Elderly with High-Dementia Risks)

  • 송재은;최성혜;홍창형;정지향;문소영;나해리;박희경;박유경
    • 대한영양사협회학술지
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    • 제27권4호
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    • pp.248-262
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    • 2021
  • This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60~79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.

Hepatoprotective Effect of Lactic Acid Bacteria, Inhibitors of $\beta$-Glucuronidase Production Against Intestinal Microflora

  • Han Song Yi;Huh Chul Sung;Ahn Young Tae;Lim Kwang Sei;Baek Young Jin;Kim Dong Hyun
    • Archives of Pharmacal Research
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    • 제28권3호
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    • pp.325-329
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    • 2005
  • The hepatoprotective activity of lactic acid bacteria (Lactobacillus brevis HY7401, Lactobacillus acidophilus CSG and Bifidobacterium longum HY8001), which inhibited $\beta$-glucuronidase productivity of intestinal microflora, on t-BHP- or CCl$_4$-induced hepatotoxicity of mice were evaluated. These oral administration of lactic acid bacteria lowered $\beta$-glucuronidase production of intestinal microflora as well as Escherichia coli HGU-3. When lactic acid bacteria at a dose of 0.5 or 2 g (wet weight)/kg was orally administered on CCl$_4$-induced liver injury in mice, these bacteria significantly inhibited the increase of plasma alanine transferase and aspartate transferase activities by $17-57\%$ and $57-66\%$ of the $CCI_4$ control group, respectively. These lactic acid bacteria also showed the potent hepatoprotective effect against t-BHP-induced liver injury in mice. The inhibitory effects of these lactic acid bacteria were more potent than that of dimethyl diphenyl bicarboxylate (DDB), which have been used as a commercial hepatoprotective agent. Among these lactic acid bacteria, L. acidophilus CSG exhibited the most potent hepatoprotective effect. Based on these findings, we insist that an inhibitor of $\beta$-glucuronidase production in intestine, such as lactic acid bacteria, may be hepatoprotective.

RGB 컬러 이미지를 이용한 콩의 군락 피복과 엽면적에 대한 저비용 평가 (Low-cost Assessment of Canopy Light Interception and Leaf Area in Soybean Canopy Cover using RGB Color Images)

  • 이윤호;상완규;백재경;김준환;조정일;서명철
    • 한국농림기상학회지
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    • 제22권1호
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    • pp.13-19
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    • 2020
  • 본 연구는 저비용·저 노동력을 위해 RGB 컬러 이미지에서 획득한 녹색영역 값과 엽면적 그리고 군락피복 측정을 비교하였다. 시험에 사용된 품종은 국내에서 가장 많이 재배되고 있는 대원콩, 대풍콩 및 풍산나물콩을 재배하였다. 측정 시기는 엽의 4.5엽기부터 종실비대기까지 RGB 컬러 이미지를 획득하여 군락 엽면적과 피복을 비교하였다. 이미지 분석은 ExGR로 토양으로부터 식물체의 녹색 영역을 분리하였다. 분리한 녹색 영역과 실제 측정한 엽면적과 피복과는 고도의 유의성을 보였다. 본 연구 결과에서 알 수 있듯이 실제 측정한 군락 엽면적과 군락 피복과는 정의 상관관계(r2=0.84)를 보였다. 군락 이미지와 실제 측정한 군락 피복과는 고도의 정의상관관계(r2=0.94)를 보였다. 또한 군락 이미지와 실제 측정한 군락 엽면적과는 고도의 정의상관관계(r2=0.74)를 보였다. 따라서 향후 RGB 컬러 이미지로 저비용·저 노동력으로 군락 단위에서 엽면적과 피복을 손쉽게 측정할 수 있을 것으로 기대된다.