Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Evaluation of Hepatoprotective Potential of Cassia tora Leaf Extract

  • Maity, Tapan Kumar (College of Pharmaceutical Sciences At and P.O. -Mohuda, Berhampur, Dist.-Ganjam) ;
  • Mandal, Subhash C. (Department of Pharmaceutical Technology Faculty of Engineering and Technology Jadavpur University) ;
  • Mukherjee, Pulok K. (Department of Pharmaceutical Technology Faculty of Engineering and Technology Jadavpur University) ;
  • Saha, Kakali (Department of Pharmaceutical Technology Faculty of Engineering and Technology Jadavpur University) ;
  • Das, J. (University College of Medicine, University of Calcutta) ;
  • Saha, B.P. (Department of Pharmaceutical Technology Faculty of Engineering and Technology Jadavpur University) ;
  • Pal, M. (Department of Pharmaceutical Technology Faculty of Engineering and Technology Jadavpur University)
  • Published : 1997.12.01
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Abstract

Methanolic extract of the leaves of Cassia tom was evaluated for its hepatoprotective potentials in rats by inducing hepatotoxicity with carbon tetrachloride. The extract at a dose of 400 mg/kg orally showed significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.

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