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Technology Trends and Patents Analysis of Auger bit for Deep Cement Mixing (DCM) Method (심층혼합처리 공법용 오거비트의 기술동향 및 특허분석)

  • Min, Kyongnam;Lee, Dongwon;Lee, Jaewon;Kim, Keeseok;Yu, Jihyung;Jung, Chanmuk;Hoang, Truong Xuan;Kwon, Yong Kyu
    • The Journal of Engineering Geology
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    • v.28 no.3
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    • pp.431-441
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    • 2018
  • To set up the future research and development direction for Auger bit, this study analyzed publicized patent trends of Deep Cement Mixing method (DCM) in Korea, USA, Japan, and Europe. DCM method was firstly classified into wing shapes and the number of rods according to the technical scope, and secondly, classified into 8 types according to type of screw and rotation axial. A total of 2,815 patents were searched and 448 validated patents were selected through de-duplication and filtering. As a result of the analysis of the portfolio through the number of patents and growth stages, it was selected as the core technology that auger is deemed to have high growth potential and if there is a patent similar to core technology through a patent barrier analysis, the basic data is suggested to develop the design around and differentiated technologies.

A Case Study on the Test Execution for DCM using Vietnam CFBC Fly Ash Solidification Material (베트남 순환유동층 발전(CFBC) 플라이애시 고화재를 사용한 심층혼합 처리공법(DCM) 시험시공 사례)

  • Kim, Keeseok;Lee, Dongwon;Lee, Jaewon;Kwon, Yongkyu;Yu, Jihyung;Hoang, Truong Xuan;Jung, Chanmuk;Min, Kyongnam
    • Resources Recycling
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    • v.27 no.5
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    • pp.38-48
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    • 2018
  • Deep cement mixing method (DCM) is used to improve the quality of various ground type and its technical development proceeding based on performance improvements of solidification materials and mixing techniques with ground soil. In this study, it was possible to improve silty clay ground soil had 1 to 3 MPa compressive strength using solidification material that composed mainly circulating fluidized bed combustion (CFBC) power plant fly ash and reduce standard deviation of strengths from over 1.0 MPa to 0.322 MPa using improved auger bits in field test to forming more uniform bulbs than in case of using existing auger bit.

Evaluation of Antioxidant Effects of Vitamins C and E Alone and in Combination with Sorghum Bran in a Cooked and Stored Chicken Sausage

  • Shin, Dae-Keun;Yang, Han-Sul;Min, Byoung-Rok;Narciso-Gaytan, Carlos;Sanchez-Plata, Marcos X.;Ruiz-Feria, Ciro A.
    • Food Science of Animal Resources
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    • v.31 no.5
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    • pp.693-700
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    • 2011
  • To evaluate the antioxidant effects of vitamin C, vitamin E and sorghum bran, alone or in combination on chicken sausages, 9 kg of chicken thigh meat was prepared. All thigh meat was divided into seven different batches as follows; no antioxidant (CON); vitamin C (VTC), vitamin E (VTE) or sorghum bran (SOR) at 0.02%; or three different combination ratios of vitamin C, vitamin E and sorghum bran at 0.02% (VT2, 2:1:1; VT4, 4:1:1; VT6, 6:1:1). All cooked sausages were stored at $4^{\circ}C$, and six sausages per treatment were used for chemical analysis on five different storage days. As the addition of vitamin E was increased, sausages stored for 10 d had decreased redness; thereby, VTE showed the lowest CIE $a^*$ (p<0.05). Sausages mixed with vitamins and sorghum bran combinations had lower peroxide and free fatty acid values (p<0.05) when compared to sausages without antioxidants. The TBARS were the lowest in sausages containing vitamin C, vitamin E and sorghum bran at 6:1:1 ratio, and they significantly differed to CON, VTC and SOR treatments (p<0.05). Therefore, our results suggest that meat mixed with vitamins and sorghum bran had more antioxidant activity than the meat mixed with only antioxidant vitamins or without antioxidants.

Physicochemical Characteristics of Antidementia Acetylcholinesterase Inhibitor-containing Methanol Extract from Sorghum bicolor and Industrial Application (항치매성 Acetylcholinesterase저해물질을 함유하고 있는 수수 메탄올 추출물의 특성 및 산업적 응용)

  • Song, Jung-Eun;Lee, Jong-Soo
    • The Journal of Natural Sciences
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    • v.19 no.1
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    • pp.45-55
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    • 2008
  • Alzheimer's disease is charaterized by the acetylcholine depletion, amyloid b-protein aggregation and neurofibrillary tangles. The prevention of the breakdown of acetylcholine by acetylcholinesterase (AChE) inhibitor has the best clinically therapeutic efficacy for Alzheimer's disease patients. To develop new antidementia alternative drugs or nutraceuticals, methanol extracts of Sorghum bicolor was screened from various extracts of cereals and legumes as a potent AChE inhibitor-containing extract in previous paper. In this paper, physicochemical properties of the methanol extracts was investigated. The methanol extracts was soluble by water, methanol and DMSO and had 215 nm and 282nm of maximum absorption spectra. It was also stable at 20-$100^{\circ}C$ and pH 2.0-10.0 for 1 hr. Test product was prepared by using methanol extracts from Sorghum bicolor and changes of its quality during storge at $20^{\circ}C$ and $40^{\circ}C$ were investigated. It was very stable for 8 weeks at $40^{\circ}C$.

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Temperature Effect on the Functional Expression of Human Cytochromes P450 2A6 and 2E1 in Escherichia coli

  • Yim Sung-Kun;Ahn Taeho;Jung Heung-Chae;Pan Jae-Gu;Yun Chul-Ho
    • Archives of Pharmacal Research
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    • v.28 no.4
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    • pp.433-437
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    • 2005
  • Human cytochromes P450 (GYP) 2A6 and 2E1 are of great interest because of their important roles in the oxidation of numerous drugs and carcinogens. Bacterial expression systems, especially Escherichia coli cells, have been widely used for the production of various GYP enzymes in order to obtain high yield of proteins. The expression methods usually employ longer culture time (30-72 h) at lower temperature (usually under $30^{\circ}C$). Expression levels of GYPs 2A6 and 2E1 at $37^{\circ}C$ were compared to those at $28^{\circ}C$, which is a usual temperature used in most bacterial expression systems for human GYP expression. Within 18 h the expression levels of GYPs 2A6 and 2E1 reached up to 360 and 560 nmol per liter culture at $37^{\circ}C$, respectively, which are compatible with those of 36 h culture at $28^{\circ}C$. The activities of GYPs expressed at $37^{\circ}C$ were also comparable to those expressed at $28^{\circ}C$. The present over-expression system can be useful for rapid production of large amounts of active human GYPs 2A6 and 2E1 in E. coli.

Musculoskeletal Health of the Adults Over 50 Years of Age in Relation to Antioxidant Vitamin Intakes

  • Namhee Kim;Yeji Kang;Yong Jun Choi;Yunhwan Lee;Seok Jun Park;Hyoung Su Park;Miyoung Kwon;Yoon-Sok Chung;Yoo Kyoung Park
    • Clinical Nutrition Research
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    • v.11 no.2
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    • pp.84-97
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    • 2022
  • As the proportion of the elderly population increases rapidly, interest in musculoskeletal health is also emerging. Here, we investigated how antioxidant vitamin intake and musculoskeletal health are related. Adults aged 50 to 80 years with a body mass index (BMI) of 18.5 to 27.0 kg/m2 were included. Bone mineral density (BMD), lean mass (LM), appendicular skeletal muscle mass index (ASMI) were measured using dual-energy X-ray absorptiometry (DXA), and the grip strength and knee extension using hand dynamometer. Nutrient intakes were measured using a 24-hour recall questionnaire. A total of 153 adults (44 men and 109 women) participated in this study. A partial correlation analysis showed a significant positive relationship between vitamin E and BMD and between vitamin C and LM/Height. Participants were classified into three groups according to whether their vitamin E and C intake met the recommended intake for Dietary Reference Intakes for Koreans (KDRIs). The prevalence of having low T-score (< -1.0) and low ASMI (< 7.0 for men and < 5.4 for women) was 51.3% and 15.4% in the group with vitamins C and E intakes below KDRIs. After adjusting for sex, smoking status and energy, protein, vitamin D, and calcium intake, the group with vitamins C and E both below the KDRIs displayed a significantly lower BMD at all test sites and LM/Height compared with vitamin C and/or E intake above the KDRIs groups. We conclude that sufficient intake of vitamin E and C is important for maintaining BMD and lean mass in Korean adults over 50 years of age.

Comparative analysis of running-type brassieres on the market (런닝형 브래지어의 비교분석)

  • Park, Do Yoon;Jung, Heh Soon;Na, Mi Hyang
    • The Research Journal of the Costume Culture
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    • v.20 no.5
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    • pp.621-634
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    • 2012
  • With comparative analysis of running-type brassieres on the market about suitability for middle-aged women, this study is to provide basic data of running-type brassieres' pattern which is highly suitable. In the pursuit of this purpose, this study carried out wearing experiment targeting 3 middle-aged women with normal body shape which is 85B of chest circumference. The result is as follows. The significant difference was recognized in the breast. The products were rated in order of C>A>B>D, E, F, G>H by the observers, and C>B>D>A>F>E=G>H by the subjects. The significant difference was recognized in the armhole area. The products were ranked in the order of C, D>B, G, E>A, F, H by the observes and D, C>B>G>F>A>H by the subjects. The significant difference was also recognized in 6 categories(14~19) for the torso. According to the overall average values, the products were rated in the order of B, C, D>A, D, F, G by the observers and B=D>C>H>F>G>A>E by the subjects. The overall evaluation exhibited the significant difference. The products were ranked in the order of D>C>E>B>H>A>G>F by both observers and subjects. Therefore it was confirmed that the product D was appropriate in general. To conclude of comparative analysis about 8 kinds of running-type brassieres on the market, the average values of the product C and D in all categories had high marks for each category. The product C was comfortable and capable of covering the breast well, however, a gap was formed in outside-up part. The product D, made from lacy fabric, was very comfortable and well-fitted but there was inconsistency between the mold-cup and the breast shape.

The Clinical Analysis of Ventricular Septal Defect Review of 97 cases (심실중격결손증의 임상적 고찰)

  • 백광제
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.139-150
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    • 1985
  • From 1977 through 1984, 97 patients of V.S.D. were treated surgically at Department of Thoracic and Cardiovascular Surgery, Korea University college of Medicine. Among 97 patients, 3 patients were treated by PDA ligation, 3 patients were treated by PDA ligation and subclavian flap aortoplasty, 1 patient were treated by pulmonary artery banding. All of the above patients were analyzed clinically. The results were as follows; 1. Of the patients, 52 patients were male [55.5%] and 45 patients were female [44.5%]. Their age ranged from 7 days to 32 year, and the mean age was 9 year of age and 28.9% of patients were between 4 and 8 year of age. 2. The most common clinical symptoms were frequent U.R.l. and D.O.E.. 3. The most common chest PA findings were cardiomegaly and increased pulmonary vascularity. 4. Associated anomaly was founded in 27 cases and PDA was most common associated anomaly and others were A.S.D., pulmonary stenosis, aortic regurgitation, D.C.R.V.. 5. Pulmonary hypertension was founded in 37 patients and it`s incidence was increased by patient age and shunt amount. 6. On Kirklin`s anatomical classification, type 11 defect was most common [45.5%], and type 1 was 35.5%, and type 111 was 4.4%, and type 1V was 4.4%. 7. Mean E.C.C. time was 69.1 min. and varied by closing method and associated anomaly as in case of simple closure; 47.8 min., in case of patch closure; 77.2 min., in cases with associated anomaly; 92.7 min.. 8. Mean postoperative ventilatory assisted time was 7.3 hour and varied by preoperative pulmonary artery pressure and E.C.C. time, as the group with pulmonary hypertension; 10.5 hour, the group without pulmonary hypertension; 5.5 hour, the group of short E.C.C time [within 1 hour]; 4.4 hour, the group of long E.C.C. time [over 1 hour]; 8.4 hour. 9. Overall operative mortality was 9.3% [9 cases].

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Effect of Herb Extracts Mixed with Houttuynia Cordata on Antiatopic Dermatitis in DNCB-Induced BALB/c Mouse (DNCB 유도 BALB/c 생쥐에서 어성초 혼합 한방추출물의 항아토피 효과)

  • Park, Sang-Oh;Park, Byung-Sung;Ryu, Chae-Min;Ahn, Yong-Sik
    • Journal of the Korean Applied Science and Technology
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    • v.29 no.2
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    • pp.175-183
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    • 2012
  • This study was evaluated the antiatopic activity of cream containing a herb extracts mixed with Houttuynia cordata in DNCB-induced BALB/c atopy mouse. The randomized complete block design was done by BALB/c mouse into two groups, of which the control group with atopy and the cream treatment group. It was found that each level of IgE and histamine in blood was significantly decreased in the cream treatment group, compared with the DNCB-induced atopy control group. When the cream was applied to the atopy mouse, it could be observed that its skin recovered to normal condition with the skin surface being clean and smooth without any horny tissue. The results suggest that the application of herb extracts mixed with Houttuynia cordata has an antiatopic activity through a inhibition of histamin emissions with reducing the levels of blood IgE in BALB/C atopy mouse.