• Journal of Microbiology and Biotechnology
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• 제26권10호
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• pp.1808-1816
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• 2016

As a scaffolding subunit of the PIK3C3/VPS34 complex, Beclin 1 recruits a variety of proteins to class III phosphatidylinositol-3-kinase (VPS34), resulting in the formation of a distinct PIK3C3/VPS34 complex with a specific function. Therefore, the investigation of a number of Beclin 1 domains required for the protein-protein interactions will provide important clues to understand the PIK3C3/VPS34 complex, of which Beclin1-VPS34 interaction is the core unit. In the present study, we have designed a bacterial overexpression system for the Beclin 1 domain corresponding to VPS34 binding (Vps34-BD) and set up the denaturing purification protocol due to the massive aggregation of Vps34-BD in Escherichia coli. The expression and purification conditions determined in this study successfully provided soluble and functional Vps34-BD.

• 정보처리학회논문지C
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• 제12C권2호
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• pp.207-216
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• 2005

CC내의 보안기능(클래스-패밀리-컴포넌트)을 실제 정보보호 제품이나 PP에서 사용하는 빈도에 대한 연구결과가 없으므로, 어떤 보안기능이 중요한지를 판단하기가 어렵다. 본 논문에서는 기존의 33종의 제품유형별 PP들이 CC내의 어떤 보안기능을 사용했는지를 조사하여, CC내의 보안기능들의 사용율과 제품유형별 보안기능의 사용율을 구하였다. 이 결과는 제품의 새로운 분류, 제품유형별 개발 및 평가비 산정 등에 활용할 수 있을 것이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제22권2호
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• pp.174-183
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• 2000

This study was performed to investigate the characteristics of soft tissue profile of the class III malocclusion and to test the yardstick far differential diagnosis between surgical and orthodontic patients. Initial lateral cephalograms of orthodontic group(30 patients) that have acceptable occlusion and profile by orthodontic treatment alone and surgical group(30 patients) that have favorable occlusion and profile by combined surgical-orthodontic treatment were selected in Ajou university hospital. Powell and Burstone II analysis were made on the tracing. Descriptive, comparative, factor, cluster, and discriminant analysis were carried out with computer program. The results were as followings : 1. Patients who received surgery had a more concave profile and a longer lower facial height than patients who received orthodontic treatment alone. 2. Nasolabial angle, ratio of vertical height, and mentolabial sulcus were significantly different at the 5% level. And facial protuberance, upper lip protuberance, mentocervical angle, nasofrontal angle, nasomental angle, mandibular vertical height, angle between cervix and lower face, ratio of mandibular vertical height divided by cervical depth, ratio of vertical height between upper and lower lip, and maxillary protuberance were significantly different at the 1% level. 3. 8 factors were extracted and factor 2, 3, and 8 showed significant differences by factor analysis. 4. Orthodontic group (25) and surgical group (35) were classified by cluster analysis. 5. Discriminant function was D = 0.079Nasomental angle + 0.081Sn-Gn + 3.343Sn-Gn/C-Gn + 1.734Sn-St/St-Me' -26.460, and cutting score was 0, so we can discriminate that orthodontic group has the score above 0, and surgery group below 0. And 91.7% of original grouped cases were correctly classified.

• 한국문헌정보학회지
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• 제22권
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• pp.259-304
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• 1992

This paper examines 'Religion Class' in the scheme of the DDC. The major findings of the study are summerized as follows. 1. The first edition of DDC was published in 1876 in order to classify Amherst College Library collections. In spite of the continuous study and revision of the experts, the frameworks of the DDC systems are still kept unchanged. Only their subdivisions, reflecting those developments in the academic world, are developed and detailed more sophisticatedly. 2. The division of 200 does not function as generalities for all class of religion. Therefore, it is necessary to amend the division of 200 to serve generalities for all the religions of the world. 3. Standard subdivision for the christian religion and for the non-christian religion is different. So, the mnemonic nature has become weakened due to the dual standard subdivisions and the classification number becomes much longer and complicated. Therefore, one standard subdivision for all religions of the world is required. 4. Religion science was organized in late 19 C and developed continuously, but the DDC does not accomodate the religion science as a science. Accodingly, the DDC should be revised recognize religion science as a science not the christian science. 5. The deployment of classification scheme in Dewey's 200 is severely biased. That is to say, 9 division were assigned for christian religion, whereas only 1 division was assigned for non-christian religion. Therefore, an adjustment should be made to allocate subdivisions equally to all religions of the world. 6. General classification order of religion is prehistoric, primitive, ancient, modem and world religion in religion science. But, DDC does not accept this general classification order of religion, sticking to the biased expansion towards christianity. Therefore, DDC must adopt the general classification order of religion in the religion science. 7. Lastly, because of the limitation of decimal notation in DC, DDC does not accomodate new subject equally and classification number becomes longer. Therefore, centesimal expansion is proposed in order to make the classification number short, to enlarge its capacity of inclusion of new subject and to maintain consistency in the scheme.

• Journal of Oral Medicine and Pain
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• 제16권1호
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• pp.85-93
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• 1991

In this study, 88 dental students were examined to evaluate the relationship between occlusal states and TM disorders for the epidemiologic study of TM disorders. The clinical evaluation were composed of mandibular movement, TMJ noise, occlusal states and muscle palpation. The following results were disclosed. 1. The frequencies of pain on mandibular movement were 3.4% on maximum opening, 1.13% on protrusion and no pain on laterotrusion. 2. The frequencies on TMJ sound were 21.6% in click, 1.13% in crepitus. 3. The frequency of tenderness on palpation was 12.5% on extra oral, intraoral and neck muscles, tenderness on palpation of TMJ capsule were reported 5 cases, and 4 of them were female. 4. The distribution of Angle's classification was found 79.5% in class I, 4.5% in clasII-div.1 and 15.9% in class III. There was no significant differences on TM disorders between Angles classifications. 5. There was no significant differences on TM disorders between the subjects of canine guided occlusion and group function occlusion, and also for the differences between the subjects of nonworking side interferences and no interferences on laterotrusion. 6. There was no significant differences on TM disorders between the subjects of anterior teeth trauma in C.C. and no anterior teeth trauma, but there were significant differences between the subjects of posterior protrusive contact and no posterior protrusive contact.

• 천문학회보
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• 제41권1호
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• pp.80.1-80.1
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• 2016

There are probabilistic forecast models for solar flare occurrence, which can be evaluated by various skill scores (e.g. accuracy, critical success index, heidek skill score, and true skill score). Since these skill scores assume that two types of forecast errors (i.e. false alarm and miss) are equal or constant, which does not take into account different situations of users, they may be unrealistic. In this study, we make an evaluation of a probabilistic flare forecast model [Lee et al., 2012] which use sunspot groups and its area changes as a proxy of flux emergence. We calculate daily solar flare probabilities from 2011 to 2014 using this model. The skill scores are computed through contingency tables as a function of forecast probability, which corresponds to the maximum skill score depending on flare class and type of a skill score. We use a value score with cost/loss ratio, relative importance between the two types of forecast errors. The forecast probability (y) is linearly changed with the cost/loss ratio (x) in the form of y=ax+b: a=0.88; b=0 (C), a=1.2; b=-0.05(M), a=1.29; b=-0.02(X). We find that the forecast model has an effective range of cost/loss ratio for each class flare: 0.536-0.853(C), 0.147-0.334(M), and 0.023-0.072(X). We expect that this study would provide a guideline to determine the probability threshold and the cost/loss ratio for space weather forecast.

• 한국물환경학회지
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• 제35권4호
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• pp.340-351
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• 2019

In this study, the relationship between trophic state indices was analyzed based on the monthly or weekly water quality data of 81 lakes (mostly man-made) in Korea between 2013-2017. Carlson's $TSI_C$ and Aizaki's $TSI_m$ were calculated using the summer (Jun.-Sep.) average data at the upper water layer. The previous Korean trophic state index ($TSI_{KO}$) and the newly suggested index ($TSI_{KON}$) was calculated using the annual average data at the whole layer and at the upper layer, respectively. While previous trophic state index (TSI) such as Carlson's TSI included logarithmic function, we devised newly Monod-type $TSI_{KON}$(Chl) that is 50 when half-saturation concentration of chlorophyll ${\alpha}$ ($Chl.{\alpha}$) measured by UNESCO-method is $10{\mu}gL^{-1}$. MMF-type $TSI_{KON}$(TP) was derived based on the relationship between TP and $Chl.{\alpha}$. A comprehensive $TSI_{KON}$ was decided as the larger one of the two $TSI_{KON}$ values. The range of previous TSI was usually 40-50 for the mesotrophic state, which seemed narrow to discriminate trophic characteristics of the class. The upper limits of $TSI_{KON}$ for oligotrophic, mesotrophic, and eutrophic state were set to 23, 50 and 75, respectively. Classification by $TSI_C$ and $TSI_m$ showed higher frequency of eutrophic class compared to $TSI_{KO}$ and $TSI_{KON}$. This means that the estimation by TSIs developed in foreign natural lakes can lead to distorted results in the classification of the trophic state of Korean lakes. This is due to the decrease of transparency by non-algal material and the reduction in phosphorus availability to algal growth, particularly in Monsoon period.

• 생명과학회지
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• 제17권3호통권83호
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• pp.427-434
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• 2007

본 실험에서는 일부 한약재를 이용하여 수지상세포의 활성화에 미치는 영향을 알아보았다. 그 결과, 실험에 사용한 여섯 가지 한약재 중 선별된 천궁과 당귀는 수지상세포의 항원 제시 능력에 영향을 미쳐, T 세포 증식 반응을 증가시켰고, IL-2와 IFN-r의 분비를 증가시키는 것으로 나타났다. 또한 이러한 T 세포의 활성은 수지상세포의 세포표면 단백질인 MHC classII와 CD86, 그리고 CD11c의 발현 증가에 의한 것임을 확인 할 수 있었다. 이상의 실험 결과, 본 실험에서 선별된 천궁과 당귀는 수지상세포를 활성화시키는 효과가 있는 것으로 생각된다.

• Journal of Communications and Networks
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• 제17권5호
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• pp.491-498
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• 2015

Recognition of radar emitter signals is one of core elements in radar reconnaissance systems. A novel method based on singular value decomposition (SVD) and the main ridge slice of ambiguity function (AF) is presented for attaining a higher correct recognition rate of radar emitter signals in case of low signal-to-noise ratio. This method calculates the AF of the sorted signal and ascertains the main ridge slice envelope. To improve the recognition performance, SVD is employed to eliminate the influence of noise on the main ridge slice envelope. The rotation angle and symmetric Holder coefficients of the main ridge slice envelope are extracted as the elements of the feature vector. And kernel fuzzy c-means clustering is adopted to analyze the feature vector and classify different types of radar signals. Simulation results indicate that the feature vector extracted by the proposed method has satisfactory aggregation within class, separability between classes, and stability. Compared to existing methods, the proposed feature recognition method can achieve a higher correct recognition rate.

• 대한수학회지
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• 제60권3호
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• pp.565-586
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• 2023

We study the Dirichlet problem for the degenerate nonlocal parabolic equation u_t - a(||∇u||²_L²(Ω))∆u = C_b ||u||^β_L²(Ω) |u|^q(x,t)-2 u log |u| + f in Q_T, where Q_T := Ω × (0, T), T > 0, Ω ⊂ ℝ^N, N ≥ 2, is a bounded domain with a sufficiently smooth boundary, q(x, t) is a measurable function in Q_T with values in an interval [q^-, q⁺] ⊂ (1, ∞) and the diffusion coefficient a(·) is a continuous function defined on ℝ₊. It is assumed that a(s) → 0 or a(s) → ∞ as s → 0⁺, therefore the equation degenerates or becomes singular as ||∇u(t)||2 → 0. For both cases, we show that under appropriate conditions on a, β, q, f the problem has a global in time strong solution which possesses the following global regularity property: ∆u ∈ L²(Q_T) and a(||∇u||²_L²(Ω))∆u ∈ L²(Q_T ).