• 대한의생명과학회지
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• 제12권4호
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• pp.303-310
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• 2006

Ankyrins are a ubiquitously expressed family of intracellular adaptor proteins involved in targeting diverse proteins to specialized membrane domains in both the plasma membrane and the endoplasmic reticulum. We described here that the C-terminal domain of ankyrin-B interact specifically with Z-line portion of titin in yeast two-hybrid analysis, in vitro pull-down assays and localization experiments in COS-7 cells. In this study we provide the first experimental evidence that Z-line portion of titin is necessary for the localization of ankyrin-B and ankyrin-B links between the sarcolemma and the myofibril in costameres.

• Parasites, Hosts and Diseases
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• 제43권3호
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• pp.111-114
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• 2005

The present study investigated the prevalence rate of Cryptosporidium parvum as a cause of diarrhea. We examined 942 stools of unidentified reasons occurring in patients in whom no immunosuppression had been detected. We examined the stools for Cryptosporidium parvum via modified acid-fast staining. The clinical records of all of the positive patients were then analyzed. Nine ($1\%$) of the stools among the 942 diarrheal patients were positive for C. parvum. The positive rate in the males was $1.1\%$ (6/522) and the positive rate of the females was $0.7\%$ (3/420). Age distribution revealed that the highest positive rates were in patients in their sixties, with a positive rate of $2.5\%$ (4/158). In the clinical tests, levels of c-reactive protein, erythrocyte sedimentation rates, and neutrophil proportions were normally increased in the peripheral blood, whereas the lymphocyte proportion exhibited a tendency towards decrease. The pathological findings were compatible with an inflammatory reaction in the host.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2012년도 정기총회 및 춘계학술발표회
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• pp.20-20
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• 2012

Isoprenoids represent the most diverse group of metabolites, which are functionally and structurally identified in plant organism to date. Ginsenosides, glycosylated triterpenes, are considered to be the major pharmaceutically active ingredient of ginseng. Its backbones, categorized as protopanaxadiol (PPD), protopanaxatriol (PPT), and oleanane saponin, are synthesized via the isoprenoid pathway by cyclization of 2,3-oxidosqualene mediated with dammarenediol synthase or beta-amyrin synthase. The rate-limiting 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), which is the first committed step enzyme catalyzes the cytoplasmic mevalonate (MVA) pathway for isoprenoid biosynthesis. DXP reductoisomerese (DXR), yields 2-C-methyl-D-erythritol 4-phosphate (MEP), is partly involved in isoprenoid biosynthesis via plastid. Squalene synthase and squalene epoxidase are involved right before the cyclization step. The triterpene backbone then undergoes various modifications, such as oxidation, substitution, and glycosylation. Here we will discuss general biosynthesis pathway for the production of ginsenoside and its modification based on their subcellular biological functions.

• 대한의생명과학회지
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• 제11권2호
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• pp.109-113
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• 2005

From the RT-PCR amplifications using mRNA templates isolated from Sprague-Dawley rat brains, we isolated a cDNA fragment of 1,524 bp which covered the full coding information of the rat brain CYP2El. Its nucleotide sequence was identical to the previously reported rat liver CYP2El mRNA except for the difference of one base (A to C at the nucleotide position 73). This difference also altered the amino acid Lys to GIn. However, no insertion or deletion of nucleotide(s) which could alter the reading frame was found within the structure of this rat brain CYP2El. This study should provide the molecular basis regarding the pathophysiological function of CYP2El in the brain.

• Mycobiology
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• 제47권4호
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• pp.430-440
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• 2019

Fungal contamination of built-in furniture is a frequent problem in Korea when new apartment is built. However, domestic information on the contaminating fungi is very limited. This study was conducted to isolate, identify and characterize the fungi of the problem in one of the apartment houses where the fungi were claimed in the built-in furniture before the house owner moves in. Fungi present in the furniture installed in a main room, dress room, and kitchen side were visually and microscopically confirmed and purely isolated on PDA. The isolated fungi were identified by analyzing the morphological characteristics and nucleotide sequence of the ITS, calmodulin gene, and TEF-1α gene. Aspergillus creber, A. niger, A. pseudoglacus, A. ruber, Cladosporium perangustum and Penicillium commune were identified. Four out of the six fungal species were positive for at least one enzyme in six kinds of extracellular enzyme assays. When these four species (A. creber, A. niger, C. perangustum and P. commune) were inoculated onto four kinds of wood chips of furniture materials, they were able to colonize all of the wood chips. Their settlement was better at 95% humidity condition than at 30% humidity condition. Among the four species, C. perangustum caused the darkest discoloration and secreted the most number of extracellular enzymes. The four species were re-isolated from the colonized wood chips and confirmed as the problematic fungi in the built-in furniture.

• 한국응용과학기술학회지
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• 제31권4호
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• pp.541-548
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• 2014

This study was performed to obtain high conversion efficiency of $C_7H_8$ using non-thermal plasma and metal-supported catalyst. Adsorption-desorption characteristics of toluene was performed using 4A type (Zeolite) filled in a concentration reactor. Through this test, it was found that the concentration reactor has 0.020 g/g of adsorption capacity (at ambient temperature and pressure) and 3,600 ppm of desorption property at $150^{\circ}C$ (with in 20 min). In case of developed catalyst, toluene decomposition rate of Pd-AO (Pd coated catalyst) was better than Pd/Cu-AO and Pd/Ag-AO (Pd/Ag composite metal catalyst). Developed non-thermal plasma system was obtained flame amplification effect using injection process of desorbed tolune, and 98% of removal efficiency.

• 한국지리정보학회지
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• 제1권2호
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• pp.37-43
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• 1998

본 논문에서는 우리별3호 영상데이터의 검색 및 분배시스템의 개발에 대하여 기술한다. 영상데이터 카탈로그의 검색 시스템은 위성영상 데이터 수신처리국의 운영에서 영상 사용자들과 가장 밀접하게 연결되는 부분이기 때문에 그 속도 및 사용의 편이성이 가장 중요하다. 사용자가 지상국에서 수신, 보유하고 있는 위성영상을 쉽고 빠르게 접근, 검색, 주문할 수 있는 인터페이스를 제공하는 것이 위성영상의 활용을 극대화 시킬 수 있기 때문이다. 사용자들은 자신이 원하는 영상의 검색조건을 가장 단순하게 입력할 수 있기를 바라며 검색결과가 빠르고 쉽게 이해할 수 있게 출력되기를 원한다. 본 논문에서 소개되는 개발된 우리별 3호 영상의 카탈로그 검색 및 주문 시스템은 이러한 사용자의 요구를 최대한 만족시키며 최소의 시스템 구축비용을 요구한다.

• 한국균학회지
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• 제40권4호
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• pp.187-190
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• 2012

다양한 향미를 가진 막걸리의 개발을 위해 전통누룩으로부터 분리한 곰팡이로 입국을 제조한 후 품질특성을 분석하여 입국의 규격에 적합하며 이취가 없고 관능이 우수한 9균주를 입국 제조용 우수균주로 최종 선발하였다. 선발된 균주는 Aspergillus oryzae(C1-5-2-2, C20-7-3, CN1.3.1-4, CN16.19.1-1, N152-1, N220-1), Mycocladus corymbiferus(N162-2), Rhizopus oryzae(N20), Lichtheimia corymbifera(N21)로 동정되었으며, 제조한 입국의 산도는 5.0~6.8, 당화력은 128~241sp이었다.

• Food Science and Biotechnology
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• 제16권4호
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• pp.641-645
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• 2007

Delphinidin, an aglycone form of anthocyanins, was demonstrated to have anti-carcinogenic potential. The compound at $50\;{\mu}g/mL$ caused a significant increase of quinone reductase activity, an anti-carcinogenic marker enzyme, in mouse hepatoma cell lines (Hepa1c1c7 and BPRc1). Delphinidin enhanced the expression of other detoxifying or antioxidant enzymes including glutathione s-transferase, gamma-glutamylcysteine synthetase, heme oxygenase 1, and glutathione reductase. It suppressed the proliferation of murine hepatoma cells in a dose-dependent manner, with approximately $IC_{50}$ of $70\;{\mu}g/mL$. These results suggest that delphinidin might be useful for cancer prevention.

• 정보와 통신
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• 제22권9호
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• pp.138-163
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• 2005

2세대 이동통신의 본격적인 상용화 이후, 보다 향상된 무선 멀티미디어 서비스를 지원하기 위해 ITU는 IMT-2000이라고 불리는 복수의 국제 무선 규격을 2000년에 승인하였으며 이을 통칭하여 3G(Third Generation) 이동통신 시스템이라고 부르고 있다. 특히 여러 3G 기술 표준들 가운데 3GPP(Third Generation Partnership Project)와 3GPP2(Third Generation Partnership Project)라는 양대 국제 표준화 기구에서 완성된 UMTS와 cdma20()0 @ 시스템은 현재 일본, 유럽, 미국, 국내 등지에서 본격적인 상용 서비스를 시행 또는 준비 중에 있다. 초기 3G 표준의 제정 이후, 각 표준화 기구들은 상향과 하향 링크의 양방향 모두에서의 고속 패킷 데이터 전송, 무선 성능 향상, IP 네트워크를 위한 구조의 진화, 향상된 서비스 등을 목표로 하여 3G 무선 규격에 대한 성능 향상 및 진화를 위한 표준화 작업을 진행해 왔으며 또한 현재에도 진행 중에 있다. 최근에 이르러3GPP에서는 장기적 관점에서 향후 시스템의 진화 (Long-Term Evolution: LTE) 방향에 대한 논의가 활발히 진행되고 있으며, 3GPP2 TSG-C에서도 진화 방향에 대한 논의가 구체화되기 시작하였다. 본 논문 에서는 3GPP/3GPP2 표준화 동향 및 각 표준화 단체의 최종 진화 시스템에 대한 다양한 방향성을 가늠해 본다.